Page last updated: 2024-10-21

phenytoin and Dystonia

phenytoin has been researched along with Dystonia in 13 studies

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
" Phenytoin induced dystonia."7.88Phenytoin induced dystonia. ( Acar, T; Alkan, G; Çaksen, H; Cander, B; Ergin, M; Ertekin, B; Koçak, S, 2018)
" Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate."4.77Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985)
" Rare reports have been made for dyskinesia, a type of dystonia caused by phenytoin."4.31Phenytoin-induced dyskinesia: a case report. ( Chavda, VP; Khadela, A; Patel, NS; Shah, KC; Vasani, P; Vora, L, 2023)
" Phenytoin induced dystonia."3.88Phenytoin induced dystonia. ( Acar, T; Alkan, G; Çaksen, H; Cander, B; Ergin, M; Ertekin, B; Koçak, S, 2018)
"She also had a past history of partial seizures with secondary generalization in her childhood."1.43Paroxysmal Kinesigenic Dyskinesia. ( Mallik, R; Nandi, SS, 2016)
"We have observed acute dystonias in the absence of antipsychotic treatment and in the context of seizure activity (or paroxysmal dyskinetic activity)."1.33High vulnerability to acute dystonic reactions: a case of antipsychotic exposure and uncontrolled seizure activity. ( Botts, SR; Coffey, GL; de Leon, J, 2005)
"Treatment with phenytoin resulted in a marked reduction in the frequency of the episodes."1.27Concurrent hypnogenic and reflex paroxysmal dystonia. ( De Arbelaiz, R; Lehkuniec, E; Micheli, F; Paradiso, G; Torres, M, 1988)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Shah, KC1
Patel, NS1
Vasani, P1
Khadela, A1
Chavda, VP1
Vora, L1
Acar, T1
Alkan, G1
Çaksen, H1
Ertekin, B1
Ergin, M1
Koçak, S1
Cander, B1
Mallik, R1
Nandi, SS1
Hamann, M1
Meisler, MH1
Richter, A1
Coffey, GL1
Botts, SR1
de Leon, J1
Choonara, IA1
Rosenbloom, L1
Jacome, DE1
Risko, M1
Corey, A1
Koller, W1
Auchus, AP1
Freeman, A1
Green, RC1
Moss, W1
Ojukwu, C1
Chiriboga, CA1
Fredow, G1
Löscher, W1
Reynolds, EH1
Trimble, MR1
Lehkuniec, E1
Micheli, F1
De Arbelaiz, R1
Torres, M1
Paradiso, G1

Reviews

1 review available for phenytoin and Dystonia

ArticleYear
Adverse neuropsychiatric effects of anticonvulsant drugs.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba

1985

Other Studies

12 other studies available for phenytoin and Dystonia

ArticleYear
Phenytoin-induced dyskinesia: a case report.
    Journal of medical case reports, 2023, Jul-21, Volume: 17, Issue:1

    Topics: Anticonvulsants; Dyskinesia, Drug-Induced; Dystonia; Humans; Levetiracetam; Middle Aged; Phenytoin

2023
Phenytoin induced dystonia.
    The Turkish journal of pediatrics, 2018, Volume: 60, Issue:1

    Topics: Anticonvulsants; Child, Preschool; Dystonia; Epilepsy; Humans; Male; Phenytoin; Primidone

2018
Paroxysmal Kinesigenic Dyskinesia.
    The Journal of the Association of Physicians of India, 2016, Volume: 64, Issue:4

    Topics: Adult; Anticonvulsants; Chorea; Dystonia; Female; Humans; Phenytoin; Seizures; Young Adult

2016
Motor disturbances in mice with deficiency of the sodium channel gene Scn8a show features of human dystonia.
    Experimental neurology, 2003, Volume: 184, Issue:2

    Topics: Animals; Anti-Dyskinesia Agents; Anticonvulsants; Biperiden; Brain; Diazepam; Disease Models, Animal

2003
High vulnerability to acute dystonic reactions: a case of antipsychotic exposure and uncontrolled seizure activity.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:5

    Topics: Anticonvulsants; Antipsychotic Agents; Chronic Disease; Cytochrome P-450 CYP2D6; Dibenzothiazepines;

2005
Focal dystonic reaction to phenytoin.
    Developmental medicine and child neurology, 1984, Volume: 26, Issue:5

    Topics: Adolescent; Drug Therapy, Combination; Dystonia; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Hu

1984
Photic induced-driven PLEDs in paroxysmal dystonic choreoathetosis.
    Clinical EEG (electroencephalography), 1984, Volume: 15, Issue:3

    Topics: Aged; Athetosis; Chorea; Drug Resistance; Dystonia; Electroencephalography; Female; Humans; Movement

1984
Phenytoin-induced dystonia.
    Annals of neurology, 1983, Volume: 14, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Dystonia; Epilepsy, Temporal Lobe; Humans; Male; Phenytoin

1983
Agitated behavior relieved following treatment of cervical dystonia in dementia.
    Neurology, 1995, Volume: 45, Issue:2

    Topics: Alzheimer Disease; Botulinum Toxins; Chlorpromazine; Dystonia; Female; Humans; Isoxazoles; Middle Ag

1995
Phenytoin-induced movement disorder. Unilateral presentation in a child and response to diphenhydramine.
    Clinical pediatrics, 1994, Volume: 33, Issue:10

    Topics: Child, Preschool; Diphenhydramine; Dyskinesia, Drug-Induced; Dystonia; Facial Muscles; Female; Hemip

1994
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
    European journal of pharmacology, 1991, Jan-10, Volume: 192, Issue:2

    Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Amin

1991
Concurrent hypnogenic and reflex paroxysmal dystonia.
    Movement disorders : official journal of the Movement Disorder Society, 1988, Volume: 3, Issue:4

    Topics: Adult; Dystonia; Electroencephalography; Foot; Humans; Male; Phenytoin; Reflex; Sleep Stages; Touch

1988