Compounds > phenytoin
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phenytoin and Dyskinesia, Drug-Induced

phenytoin has been researched along with Dyskinesia, Drug-Induced in 34 studies

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
" Rare reports have been made for dyskinesia, a type of dystonia caused by phenytoin."4.31Phenytoin-induced dyskinesia: a case report. ( Chavda, VP; Khadela, A; Patel, NS; Shah, KC; Vasani, P; Vora, L, 2023)
" He developed partial complex status epilepticus, requiring benzodiazepines, phenytoin, propofol and intubation."3.81Medication-induced acute dystonic reaction: the challenge of diagnosing movement disorders in the intensive care unit. ( Digby, G; Jalini, S; Taylor, S, 2015)
" She had been diagnosed with idiopathic epilepsy and was given phenytoin 2 months before admission to our hospital."3.72Use of biperiden hydrochloride in a child with severe dyskinesia induced by phenytoin. ( Anlar, O; Caksen, H; Odabaş, D, 2003)
"A 56-year-old man with a small glioblastoma multiforme in the right parasagittal region developed orofacial dyskinesia and slight writhing movement of his hands during treatment with phenytoin and phenobarbitone."3.67Phenytoin-induced orofacial dyskinesia. A case report. ( Nakanishi, T; Ozaki, Y; Yamada, S; Yoshida, M, 1985)
"Chorea is a rare side effect of anticonvulsants."1.31Anticonvulsants-induced chorea: a role for pharmacodynamic drug interaction? ( Beach, RL; D'Cruz, O; Tennison, M; Zaatreh, M, 2001)
"Phenytoin is an effective antiepileptic drug, although, it can be associated with many side effects, including dyskinesia."1.30Dyskinesia induced by phenytoin. ( Cendes, F; Montenegro, MA; Scotoni, AE, 1999)
" She had been treated for hypothyroidism as well as migraine with abnormal electroencephalogram since age 47, and was given a daily dosage of 70 mg phenytoin, 80 mg phenobal, and 125 mg dried thyroid."1.28[A case of involuntary movements probably produced by low doses of phenytoin intoxication]. ( Itou, H; Morimatsu, M; Noda, S; Umezaki, H; Yamamoto, K, 1990)
" PHT dosage had been increased 4 months earlier."1.27[Recurrent acute dyskinesia as the sole manifestation of phenytoin poisoning]. ( Koskas, P; Mahieux, F; Marteau, R; Roullet, E, 1987)
"We conclude that phenytoin induced hyperkinesias reflect a specific effect of phenytoin on an abnormal neural substrate and suggest the presence of an otherwise silent pathological alteration of the corpus striatum."1.26Clinical and experimental studies of phenytoin-induced hyperkinesias. ( Klawans, HL; Koller, WC; Nausieda, PA; Weiner, WJ, 1979)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199016 (47.06)18.7374
1990's7 (20.59)18.2507
2000's5 (14.71)29.6817
2010's4 (11.76)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Marefi, A1
Srour, M1
Shah, KC1
Patel, NS1
Vasani, P1
Khadela, A1
Chavda, VP1
Vora, L1
Rajasekharan, C1
Tina, AM1
Renjith, SW1
Gunduz, T1
Kocasoy-Orhan, E1
Hanagasi, HA1
Digby, G1
Jalini, S1
Taylor, S1
Thodeson, DM1
Reiber, DC1
Dolce, AM1
Sirsi, D1
Caksen, H1
Odabaş, D1
Anlar, O1
Luszczki, JJ1
Antkiewicz-Michaluk, L1
Czuczwar, SJ1
Lee, CH1
Li, JY1
Alphs, L1
Davis, JM1
Dravet, C1
Dalla Bernardina, B1
Mesdjian, E1
Galland, MC1
Roger, J1
Moss, W1
Ojukwu, C1
Chiriboga, CA1
Harrison, MB1
Lyons, GR1
Landow, ER1
Meisheri, YV1
Chaudhary, N1
Ravat, SH1
Shah, PU1
Montenegro, MA1
Scotoni, AE1
Cendes, F1
Chi, WM1
Chua, KS1
Kong, KH1
Zaatreh, M1
Tennison, M1
D'Cruz, O1
Beach, RL1
Rasmussen, S1
Kristensen, M1
Nausieda, PA2
Koller, WC2
Weiner, WJ2
Klawans, HL2
Fanø, N1
DeVeaugh-Geiss, J1
Chadwick, D1
Reynolds, EH1
Marsden, CD1
Sethi, KD1
Hitri, A1
Diamond, BI1
Yamamoto, K1
Noda, S1
Itou, H1
Umezaki, H1
Morimatsu, M1
Yoshida, M1
Yamada, S1
Ozaki, Y1
Nakanishi, T1
Lepore, V1
Di Reda, N1
Defazio, G1
Pedone, D1
Giovine, A1
Lanzi, C1
Tartaglione, B1
Livrea, P1
Kurata, K1
Kido, H1
Kobayashi, K1
Yamaguchi, N1
Roullet, E1
Koskas, P1
Mahieux, F1
Marteau, R1
Maiti, B1
Saha, P1
Howrie, DL1
Crumrine, PK1
Royer, P1

Reviews

1 review available for phenytoin and Dyskinesia, Drug-Induced

ArticleYear
Phenytoin and dyskinesias: a report of two cases and review of the literature.
    Movement disorders : official journal of the Movement Disorder Society, 1993, Volume: 8, Issue:1

    Topics: Aged; Cerebral Infarction; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Epilepsy, Tem

1993

Other Studies

33 other studies available for phenytoin and Dyskinesia, Drug-Induced

ArticleYear
The epilepsy-movement disorder phenotypic spectrum and phenytoin-induced dyskinesia associated with GABRB3 pathogenic variants.
    Epileptic disorders : international epilepsy journal with videotape, 2021, Dec-01, Volume: 23, Issue:6

    Topics: Dyskinesia, Drug-Induced; Epilepsy; Humans; Movement Disorders; Phenytoin; Receptors, GABA-A

2021
Phenytoin-induced dyskinesia: a case report.
    Journal of medical case reports, 2023, Jul-21, Volume: 17, Issue:1

    Topics: Anticonvulsants; Dyskinesia, Drug-Induced; Dystonia; Humans; Levetiracetam; Middle Aged; Phenytoin

2023
Orofaciolingual dyskinesia due to diphenylhydantoin sodium.
    BMJ case reports, 2013, May-23, Volume: 2013

    Topics: Anticonvulsants; Dyskinesia, Drug-Induced; Female; Humans; Middle Aged; Phenytoin

2013
Orolingual dyskinesia and involuntary neck movements caused by phenytoin intoxication.
    The Journal of neuropsychiatry and clinical neurosciences, 2013,Fall, Volume: 25, Issue:4

    Topics: Aged, 80 and over; Anticonvulsants; Dyskinesia, Drug-Induced; Female; Humans; Movement; Neck; Phenyt

2013
Medication-induced acute dystonic reaction: the challenge of diagnosing movement disorders in the intensive care unit.
    BMJ case reports, 2015, Sep-21, Volume: 2015

    Topics: Antipsychotic Agents; Benzodiazepines; Brain; Diphenhydramine; Dyskinesia, Drug-Induced; Haloperidol

2015
Fosphenytoin-induced dyskinesias in an infant with Sturge-Weber syndrome.
    Neurology, 2016, 04-19, Volume: 86, Issue:16

    Topics: Anticonvulsants; Dyskinesia, Drug-Induced; Electroencephalography; Female; Humans; Infant; Phenytoin

2016
Use of biperiden hydrochloride in a child with severe dyskinesia induced by phenytoin.
    Journal of child neurology, 2003, Volume: 18, Issue:7

    Topics: Anticonvulsants; Biperiden; Child, Preschool; Dyskinesia, Drug-Induced; Electroencephalography; Epil

2003
1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model.
    Neuropharmacology, 2006, Volume: 50, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Electroshoc

2006
Phenytoin intoxication and upper facial dyskinesia: an unusual presentation.
    Movement disorders : official journal of the Movement Disorder Society, 2008, Jun-15, Volume: 23, Issue:8

    Topics: Anticonvulsants; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Epilepsy, Tonic-Clonic;

2008
Psychoactive drug treatment in retarded populations.
    Psychopharmacology bulletin, 1982, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Behavior; Child; Dyskinesia, Drug-Induced; Humans; Intellec

1982
Noncatecholaminergic treatments of tardive dyskinesia.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Amantadine; Anti-Anxiety Agents; Benzodiazepines; Cyproheptadine; D-Ala(2),MePhe(4),Met(0)-ol-enkeph

1982
[Paroxysmal dyskinesia during treatment with diphenylhydantoin].
    Revue neurologique, 1980, Volume: 136, Issue:1

    Topics: Adult; Brain Diseases; Child; Child, Preschool; Diazepam; Dyskinesia, Drug-Induced; Epilepsy; Female

1980
Phenytoin-induced movement disorder. Unilateral presentation in a child and response to diphenhydramine.
    Clinical pediatrics, 1994, Volume: 33, Issue:10

    Topics: Child, Preschool; Diphenhydramine; Dyskinesia, Drug-Induced; Dystonia; Facial Muscles; Female; Hemip

1994
Simultaneous phenytoin and warfarin toxicity on chronic concomitant therapy.
    The Journal of the Association of Physicians of India, 1996, Volume: 44, Issue:9

    Topics: Adult; Anticoagulants; Anticonvulsants; Diplopia; Drug Therapy, Combination; Dysarthria; Dyskinesia,

1996
Phenytoin induced dyskinesia.
    Indian pediatrics, 1998, Volume: 35, Issue:3

    Topics: Anticonvulsants; Child; Dyskinesia, Drug-Induced; Humans; Male; Phenytoin; Seizures

1998
Dyskinesia induced by phenytoin.
    Arquivos de neuro-psiquiatria, 1999, Volume: 57, Issue:2B

    Topics: Anticonvulsants; Child; Child, Preschool; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Age

1999
Phenytoin-induced asterixis--uncommon or under-diagnozed?
    Brain injury, 2000, Volume: 14, Issue:9

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans;

2000
Anticonvulsants-induced chorea: a role for pharmacodynamic drug interaction?
    Seizure, 2001, Volume: 10, Issue:8

    Topics: Anticonvulsants; Child, Preschool; Chorea; Drug Synergism; Drug Therapy, Combination; Dyskinesia, Dr

2001
Choreoathetosis during phenytoin treatment.
    Acta medica Scandinavica, 1977, Volume: 201, Issue:3

    Topics: Aged; Athetosis; Chorea; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Epilepsy, Tonic

1977
Clinical and experimental studies of phenytoin-induced hyperkinesias.
    Journal of neural transmission, 1979, Volume: 45, Issue:4

    Topics: Aged; Animals; Apomorphine; Basal Ganglia; Corpus Striatum; Dextroamphetamine; Disease Models, Anima

1979
[Choreoathetosis and orofacial dyskinesia during phenytoin treatment].
    Ugeskrift for laeger, 1978, Nov-20, Volume: 140, Issue:47

    Topics: Adolescent; Adult; Athetosis; Chorea; Dyskinesia, Drug-Induced; Female; Humans; Male; Phenytoin; Pre

1978
Aggravation of tardive dyskinesia by phenytoin.
    The New England journal of medicine, 1978, Feb-23, Volume: 298, Issue:8

    Topics: Acute Disease; Dyskinesia, Drug-Induced; Humans; Male; Middle Aged; Phenytoin

1978
Phenytoin and choreic movements.
    The New England journal of medicine, 1978, May-11, Volume: 298, Issue:19

    Topics: Chorea; Dyskinesia, Drug-Induced; Female; Humans; Phenytoin; Tranquilizing Agents

1978
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.
    Journal of neurology, neurosurgery, and psychiatry, 1976, Volume: 39, Issue:12

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Chorea; Dyskinesia, Dr

1976
Phenytoin potentiation of neuroleptic-induced dyskinesias.
    Movement disorders : official journal of the Movement Disorder Society, 1990, Volume: 5, Issue:4

    Topics: Animals; Chlorpromazine; Corpus Striatum; Drug Synergism; Dyskinesia, Drug-Induced; Male; Phenytoin;

1990
[A case of involuntary movements probably produced by low doses of phenytoin intoxication].
    Rinsho shinkeigaku = Clinical neurology, 1990, Volume: 30, Issue:5

    Topics: Administration, Oral; Dyskinesia, Drug-Induced; Electromyography; Female; Humans; Middle Aged; Migra

1990
Phenytoin-induced orofacial dyskinesia. A case report.
    Journal of neurology, 1985, Volume: 231, Issue:6

    Topics: Brain Neoplasms; Cerebral Cortex; Dyskinesia, Drug-Induced; Electroencephalography; Face; Glioblasto

1985
Dopaminomimetic action of diphenylhydantoin in rat striatum: effect on homovanillic acid and cyclic AMP levels.
    Psychopharmacology, 1985, Volume: 86, Issue:1-2

    Topics: Animals; Apomorphine; Corpus Striatum; Cyclic AMP; Dyskinesia, Drug-Induced; Haloperidol; Homovanill

1985
Long-lasting movement disorder induced by intravenous phenytoin administration for status epilepticus. A case report.
    Clinical neuropharmacology, 1988, Volume: 11, Issue:5

    Topics: Adult; Dyskinesia, Drug-Induced; Female; Humans; Injections, Intravenous; Meningoencephalitis; Pheny

1988
[Recurrent acute dyskinesia as the sole manifestation of phenytoin poisoning].
    Revue neurologique, 1987, Volume: 143, Issue:12

    Topics: Adult; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Humans; Phenytoin; Recurr

1987
Phenytoin intoxication with activated seizure and dyskinesia.
    The Journal of the Association of Physicians of India, 1987, Volume: 35, Issue:8

    Topics: Adolescent; Dyskinesia, Drug-Induced; Humans; Male; Phenytoin; Seizures

1987
Phenytoin-induced movement disorder associated with intravenous administration for status epilepticus.
    Clinical pediatrics, 1985, Volume: 24, Issue:8

    Topics: Child; Diagnostic Errors; Dyskinesia, Drug-Induced; Female; Humans; Infant; Male; Monitoring, Physio

1985
[Postnatal effects of intrauterine chemical stress].
    Archives francaises de pediatrie, 1985, Volume: 42, Issue:5

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Dyskinesia, Drug-Induced; Failure to Thrive; Female; Fet

1985