phenytoin has been researched along with Drug Overdose in 55 studies
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is some evidence that long-term phenytoin (PHT) use may occasionally give rise to irreversible cerebellar atrophy, but it is unclear whether such changes can occur after acute PHT intoxication." | 7.69 | Cerebellar atrophy after acute phenytoin intoxication. ( Bharucha, NE; Kuruvilla, T, 1997) |
| "He also had visual hallucinations and temporary high blood pressure." | 5.37 | Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report. ( Kato, S; Kobayashi, T; Saito, N; Shioda, K; Suda, S, 2011) |
| "Phenytoin is commonly prescribed to prevent postoperative seizures." | 4.31 | Phenytoin Intoxication in a Patient Receiving a Therapeutic Dose for Postoperative Seizure Prophylaxis: A Case Study. ( Chomchai, S; Mekavuthikul, P; Phuditshinnapatra, J; Prasertsup, W, 2023) |
| " Using this assay, we examined polymorphisms in 20 Japanese pediatric patients prescribed phenytoin for the treatment of epilepsy, and classified their polymorphisms into four groups: group I, CYP2C9*1/*1 and CYP2C19*1/*1; group II, CYP2C9*1/*1 and CYP2C19*1/*2 or *1/*3; group III, CYP2C9*1/*1 and CYP2C19*2/*2; and group IV, CYP2C9*1/*3 and CYP2C19*1/*2 or *1/*3." | 3.77 | [Development of rapid genotyping methods for single nucleotide polymorphisms of cytochrome P450 2C9 (CYP2C9) and cytochrome P450 2C19 (CYP2C19) and their clinical application in pediatric patients with epilepsy]. ( Ikumi, Y; Kagawa, Y; Mishima, N; Nishimura, S; Takahashi, Y; Yamamoto, Y, 2011) |
| "A women with a prehistory of cerebral seizures was presented following a severe iatrogenic phenytoin overdose with a peak plasma concentration of 117 mg/L." | 3.74 | Treatment of severe intravenous phenytoin overdose with hemodialysis and hemoperfusion. ( Eyer, F; Felgenhauer, N; Pfab, R; Thürmel, K; Zilker, T, 2008) |
| " Following phenytoin administration, the patient developed acute severe bradycardia, refractory to atropine and adrenaline." | 3.73 | Is phenytoin administration safe in a hypothermic child? ( Arora, R; Bhagat, H; Bithal, PK; Chouhan, RS, 2006) |
| " We report a child presenting with ileus, hypothermia and lethargy after receiving supratherapeutic dosing of phenytoin after a concentration miscalculation." | 3.73 | Unusual presentation of iatrogenic phenytoin toxicity in a newborn. ( DeGreeff, J; Lowry, JA; Scalzo, AJ; Vandover, JC, 2005) |
| "A 31-year-old woman who had a severe head injury was treated with oral phenytoin (100 mg 3 times a day) to prevent posttraumatic seizures." | 3.71 | Severe phenytoin intoxication in a subject homozygous for CYP2C9*3. ( Brandolese, R; Gusella, M; Padrini, R; Scordo, MG; Spina, E, 2001) |
| "There is some evidence that long-term phenytoin (PHT) use may occasionally give rise to irreversible cerebellar atrophy, but it is unclear whether such changes can occur after acute PHT intoxication." | 3.69 | Cerebellar atrophy after acute phenytoin intoxication. ( Bharucha, NE; Kuruvilla, T, 1997) |
| "A 19-year-old woman presented with status epilepticus and ventricular dysrhythmias less than one hour after ingesting 5,000 mg dimenhydrinate (Dramamine)." | 3.68 | Fatality secondary to massive overdose of dimenhydrinate. ( McDonnell, KP; Winn, RE, 1993) |
| "Phenytoin toxicity may result from intentional overdose, dosage adjustments, drug interactions, or alterations in physiology." | 2.43 | Phenytoin poisoning. ( Craig, S, 2005) |
| "Epilepsy affects 1." | 2.41 | New antiepileptic drugs and preparations. ( Jagoda, A; Yoon, Y, 2000) |
| "Moreover, the seizure and the epilepsy type may have been incorrectly diagnosed." | 2.40 | Antiepileptic drug-induced worsening of seizures in children. ( Belmonte, A; Genton, P; Guerrini, R, 1998) |
| "Tonic seizures occurred several times on hospital day 2; thus, we resumed levetiracetam via a nasogastric tube." | 1.43 | Acute onset of a tonic seizure in a phenytoin-overdosed patient who had taken phenytoin and levetiracetam daily. ( Hayakawa, K; Kinoshita, T; Kitamoto, T; Nakamori, Y; Saito, F, 2016) |
| "To unmask or exacerbate a Brugada ECG pattern, class IA or IC antiarrhythmic agents are used, and clinicians can predict sudden cardiac death in a high-risk patient." | 1.43 | Type 1 Brugada pattern ECG due to supra-therapeutic phenytoin level. ( Bhattarai, B; Dufresne, A; Swe, T, 2016) |
| "He also had visual hallucinations and temporary high blood pressure." | 1.37 | Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report. ( Kato, S; Kobayashi, T; Saito, N; Shioda, K; Suda, S, 2011) |
| "Marked cerebellar dysfunction and persistent vomiting were observed, with an initial serum phenytoin concentration of 181 micromol/L." | 1.32 | Phenytoin overdose complicated by prolonged intoxication and residual neurological deficits. ( Craig, S, 2004) |
| "Phenytoin toxicity was defined by clinical features and correlated with drug levels." | 1.31 | Elimination of phenytoin in toxic overdose. ( Chan, SP; Chua, HC; Tjia, H; Venketasubramanian, N, 2000) |
| "Free phenytoin concentration was measured by the Amicon multi-micro ultrafiltration system." | 1.29 | A graphical nomogram method for predicting toxic concentrations of unbound phenytoin. ( Pelclová, D; Pospisil, J, 1994) |
| "Phenytoin elimination was more rapid than was expected, based on previously reported phenytoin pharmacokinetic parameters." | 1.28 | Pharmacokinetic simulation of the effect of multiple-dose activated charcoal in phenytoin poisoning--report of two pediatric cases. ( Dolgin, JG; Nix, DE; Sanchez, J; Watson, WA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (7.27) | 18.7374 |
| 1990's | 14 (25.45) | 18.2507 |
| 2000's | 23 (41.82) | 29.6817 |
| 2010's | 13 (23.64) | 24.3611 |
| 2020's | 1 (1.82) | 2.80 |
| Authors | Studies |
|---|---|
| Prasertsup, W | 1 |
| Chomchai, S | 1 |
| Mekavuthikul, P | 1 |
| Phuditshinnapatra, J | 1 |
| Kitamoto, T | 1 |
| Nakamori, Y | 1 |
| Hayakawa, K | 1 |
| Saito, F | 1 |
| Kinoshita, T | 1 |
| Grageda, M | 1 |
| Saini, AP | 1 |
| Trout, LC | 1 |
| Cyran, SE | 1 |
| Halstead, ES | 1 |
| Kang, CK | 1 |
| Kim, MK | 1 |
| Kim, MJ | 1 |
| Jun, KI | 1 |
| Kim, KW | 1 |
| Park, SH | 1 |
| Song, KH | 1 |
| Hoffman, RS | 2 |
| Gross, MH | 1 |
| Fuh, L | 1 |
| Hays, H | 1 |
| Brown, N | 1 |
| Shirk, MB | 1 |
| Avcil, M | 1 |
| Duman, A | 1 |
| Turkdogan, KA | 1 |
| Kapci, M | 1 |
| Akoz, A | 1 |
| Canakci, SE | 1 |
| Ozluer, YE | 1 |
| Swe, T | 1 |
| Bhattarai, B | 1 |
| Dufresne, A | 1 |
| Cormier, MJ | 1 |
| Desmeules, S | 1 |
| St-Onge, M | 1 |
| Ghannoum, M | 2 |
| NAUTH-MISIR, TN | 1 |
| Nixon, AC | 1 |
| Doak, MW | 1 |
| Crozier, H | 1 |
| Crooks, DP | 1 |
| Waring, WS | 1 |
| Eyer, F | 1 |
| Felgenhauer, N | 1 |
| Pfab, R | 1 |
| Thürmel, K | 1 |
| Zilker, T | 1 |
| Troyanov, S | 1 |
| Ayoub, P | 1 |
| Lavergne, V | 1 |
| Hewlett, T | 1 |
| Yamamoto, Y | 1 |
| Takahashi, Y | 1 |
| Nishimura, S | 1 |
| Ikumi, Y | 1 |
| Mishima, N | 1 |
| Kagawa, Y | 1 |
| Kobayashi, T | 1 |
| Saito, N | 1 |
| Suda, S | 1 |
| Shioda, K | 1 |
| Kato, S | 1 |
| Skinner, CG | 1 |
| Chang, AS | 1 |
| Matthews, AS | 1 |
| Reedy, SJ | 1 |
| Morgan, BW | 1 |
| Venci, JV | 1 |
| Rowcliffe, MM | 1 |
| Wollenberg, L | 1 |
| Rainka, MM | 1 |
| Gengo, FM | 1 |
| Berger, I | 1 |
| Steinberg, A | 1 |
| Schlesinger, Y | 1 |
| Seelenfreund, M | 1 |
| Schimmel, MS | 1 |
| Nghiem, DD | 1 |
| Sen, S | 1 |
| Ratnaraj, N | 1 |
| Davies, NA | 1 |
| Mookerjee, RP | 1 |
| Cooper, CE | 1 |
| Patsalos, PN | 1 |
| Williams, R | 1 |
| Jalan, R | 1 |
| Isbister, GK | 1 |
| Balit, CR | 1 |
| Whyte, IM | 1 |
| Dawson, A | 1 |
| FIER, M | 1 |
| GOLDBERG, MA | 1 |
| Craig, S | 2 |
| Sung, SF | 1 |
| Chiang, PC | 1 |
| Tung, HH | 1 |
| Ong, CT | 1 |
| Wilding, P | 1 |
| Heath, DA | 1 |
| Adams, BK | 1 |
| Mann, MD | 1 |
| Aboo, A | 1 |
| Isaacs, S | 1 |
| Evans, A | 1 |
| Vannaprasaht, S | 1 |
| Tawalee, A | 1 |
| Mayurasakorn, N | 1 |
| Yodwut, C | 1 |
| Bansong, R | 1 |
| Reungjui, S | 1 |
| Tiamkao, S | 1 |
| Bhagat, H | 1 |
| Bithal, PK | 1 |
| Chouhan, RS | 1 |
| Arora, R | 1 |
| Cook, MD | 1 |
| Williams, SR | 1 |
| Clark, RF | 1 |
| Lowry, JA | 1 |
| Vandover, JC | 1 |
| DeGreeff, J | 1 |
| Scalzo, AJ | 1 |
| Stork, CM | 1 |
| Luef, G | 2 |
| Chemelli, A | 1 |
| Birbamer, G | 2 |
| Aichner, F | 2 |
| Bauer, G | 2 |
| Wiley, JF | 1 |
| Pospisil, J | 1 |
| Pelclová, D | 1 |
| Sauter, K | 1 |
| Kaufman, HH | 1 |
| Bloomfield, SM | 1 |
| Cline, S | 1 |
| Banks, D | 1 |
| Winn, RE | 1 |
| McDonnell, KP | 1 |
| Burtscher, J | 1 |
| Kremser, C | 1 |
| Felber, S | 1 |
| Stevenson, CM | 1 |
| Kim, J | 1 |
| Fleisher, D | 1 |
| Kuruvilla, T | 1 |
| Bharucha, NE | 1 |
| Guerrini, R | 1 |
| Belmonte, A | 1 |
| Genton, P | 1 |
| Kawasaki, C | 1 |
| Nishi, R | 1 |
| Uekihara, S | 1 |
| Hayano, S | 1 |
| Otagiri, M | 1 |
| Chua, HC | 1 |
| Venketasubramanian, N | 1 |
| Tjia, H | 1 |
| Chan, SP | 1 |
| Hood, C | 1 |
| Lezama, JL | 1 |
| Shah, RP | 1 |
| Adelman, HM | 1 |
| Yoshikawa, H | 1 |
| Abe, T | 1 |
| Oda, Y | 1 |
| Yoon, Y | 1 |
| Jagoda, A | 1 |
| Buchwald, AL | 1 |
| Brandolese, R | 1 |
| Scordo, MG | 1 |
| Spina, E | 1 |
| Gusella, M | 1 |
| Padrini, R | 1 |
| Spiller, HA | 1 |
| Carlisle, RD | 1 |
| Bey, P | 1 |
| Bey, TA | 1 |
| Dolgin, JG | 1 |
| Nix, DE | 1 |
| Sanchez, J | 1 |
| Watson, WA | 1 |
| Wyte, CD | 1 |
| Berk, WA | 1 |
| Scharf, J | 1 |
| Ruder, H | 1 |
| Harms, D | 1 |
| Ros, SP | 1 |
| Black, LE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Randomized Study of Multidose Activated Charcoal in Supratherapeutic Phenytoin Serum Levels[NCT00823264] | 17 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
We enrolled patients with elevated phenytoin levels into the study with greater than 30 ug/cc. The treatment arm received multiple doses of activated charcoal and the control arm received no activated charcoal. We obtained serum phenytoin levels every 6 hours for 24 hours then once every 24 hours. The time to reach a subtoxic level was determined in each arm by looking at serum phenytoin levels and documenting when it was below 25 ug/cc. (NCT00823264)
Timeframe: Serum phenytoin levels were obtained every 6 hours for 24 hours then once every 24 hours
| Intervention | hours (Median) |
|---|---|
| Control | 41.1 |
| Multiple Doses of Activated Charcoal | 19.3 |
4 reviews available for phenytoin and Drug Overdose
| Article | Year |
|---|---|
Severe cardiomyopathy in an infant after iatrogenic fosphenytoin overdose.
Topics: Anticonvulsants; Cardiomyopathies; Drug Overdose; Echocardiography, Doppler; Female; Heart Function | 2014 |
Phenytoin poisoning.
Topics: Anticonvulsants; Charcoal; Drug Interactions; Drug Overdose; Heart Diseases; Humans; Nervous System | 2005 |
Antiepileptic drug-induced worsening of seizures in children.
Topics: Acute Disease; Anticonvulsants; Child; Drug Overdose; Drug-Related Side Effects and Adverse Reaction | 1998 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; | 2000 |
1 trial available for phenytoin and Drug Overdose
| Article | Year |
|---|---|
Randomized controlled study on the use of multiple-dose activated charcoal in patients with supratherapeutic phenytoin levels.
Topics: Adult; Aged; Anticonvulsants; Antidotes; Charcoal; Drug Overdose; Gait Ataxia; Hospitals, Teaching; | 2012 |
50 other studies available for phenytoin and Drug Overdose
| Article | Year |
|---|---|
Phenytoin Intoxication in a Patient Receiving a Therapeutic Dose for Postoperative Seizure Prophylaxis: A Case Study.
Topics: Craniotomy; Cytochrome P-450 CYP2C9; Drug Overdose; Female; Humans; Middle Aged; Phenytoin; Seizures | 2023 |
Acute onset of a tonic seizure in a phenytoin-overdosed patient who had taken phenytoin and levetiracetam daily.
Topics: Acute Disease; Adult; Anticonvulsants; Drug Combinations; Drug Overdose; Female; Humans; Levetiracet | 2016 |
Acute respiratory failure caused by phenytoin overdose.
Topics: Acute Disease; Anticonvulsants; Diagnosis, Differential; Drug Overdose; Humans; Male; Middle Aged; P | 2013 |
Could there be an alternative explanation for cardiomyopathy in an infant following fosphenytoin overdose?
Topics: Anticonvulsants; Cardiomyopathies; Drug Overdose; Humans; Infant; Phenytoin | 2014 |
Characterization of drug overdoses in an Ohio incarcerated population.
Topics: Adult; Aged; Anticonvulsants; Cohort Studies; Critical Care; Drug Overdose; Drug-Related Side Effect | 2016 |
Phenytoin intoxication with no symptoms correlated with serum drug level: a case study.
Topics: Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Overdose; Fema | 2015 |
Type 1 Brugada pattern ECG due to supra-therapeutic phenytoin level.
Topics: Aftercare; Anticonvulsants; Brugada Syndrome; Drug Overdose; Electrocardiography; Humans; Male; Memo | 2016 |
Phenytoin overdose treated with hemodialysis using a high cut-off dialyzer.
Topics: Anticonvulsants; Drug Overdose; Female; Humans; Male; Middle Aged; Phenytoin; Renal Dialysis | 2017 |
A case of gross overdosage of soluble phenytoin.
Topics: Drug Overdose; Humans; Phenytoin | 1948 |
Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Humans; Lamotrigine; Male; Middle Aged | 2009 |
Treatment of severe intravenous phenytoin overdose with hemodialysis and hemoperfusion.
Topics: Adult; Anticonvulsants; Drug Overdose; Female; Hemoperfusion; Humans; Phenytoin; Renal Dialysis; Sei | 2008 |
Successful hemodialysis in a phenytoin overdose: case report and review of the literature.
Topics: Adult; Anticonvulsants; Benzodiazepines; Clobazam; Drug Overdose; Ethanol; Female; Humans; Lorazepam | 2010 |
[Development of rapid genotyping methods for single nucleotide polymorphisms of cytochrome P450 2C9 (CYP2C9) and cytochrome P450 2C19 (CYP2C19) and their clinical application in pediatric patients with epilepsy].
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Child, Preschool; Cytochrome P-450 CYP2C19; Cytochro | 2011 |
Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report.
Topics: Anticonvulsants; Bipolar Disorder; Coma; Diazepam; Drug Overdose; Drug Resistance; Hallucinations; H | 2011 |
Pharmacokinetic simulation of fatal carbamazepine intoxication in 23-month old child following phenytoin discontinuation.
Topics: Anticonvulsants; Autopsy; Biotransformation; Carbamazepine; Computer Simulation; Drug Administration | 2013 |
Neonatal mydriasis: intravenous lidocaine adverse reaction.
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Diagnosis, Differential; Drug Overdose; Drug Therapy, Combi | 2002 |
Role of pharmacologic enhancement of p-450 in cyclosporine overdose.
Topics: Cyclosporine; Cytochrome P-450 Enzyme System; Drug Overdose; Humans; Male; Middle Aged; Phenytoin; P | 2002 |
Treatment of phenytoin toxicity by the molecular adsorbents recirculating system (MARS).
Topics: Anticonvulsants; Drug Overdose; Equipment Design; Hemofiltration; Humans; Kidney Failure, Chronic; L | 2003 |
Valproate overdose: a comparative cohort study of self poisonings.
Topics: Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Cohort Studies; Critical Care; Drug Ove | 2003 |
CONVULSIVE SEIZURES IN CHLORPROTHIXENE OVERDOSE.
Topics: Black People; Chlorprothixene; Drug Overdose; Humans; Methylphenidate; Phenytoin; Seizures; Toxicolo | 1964 |
Phenytoin overdose complicated by prolonged intoxication and residual neurological deficits.
Topics: Adult; Cerebellar Diseases; Charcoal; Critical Care; Drug Overdose; Emergency Medicine; Hemoperfusio | 2004 |
Charcoal hemoperfusion in an elderly man with life-threatening adverse reactions due to poor metabolism of phenytoin.
Topics: Aged; Anticonvulsants; Charcoal; Drug Hypersensitivity; Drug Overdose; Hemoperfusion; Humans; Male; | 2004 |
Effect of paracetamol on uric acid determination.
Topics: Acetaminophen; Adult; Anticonvulsants; Autoanalysis; Bromides; Diazepam; Dose-Response Relationship, | 1975 |
Prolonged gastric emptying half-time and gastric hypomotility after drug overdose.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsant | 2004 |
Ceftazidime overdose-related nonconvulsive status epilepticus after intraperitoneal instillation.
Topics: Aged; Anti-Bacterial Agents; Anticonvulsants; Ceftazidime; Drug Overdose; Electroencephalography; Fe | 2006 |
Is phenytoin administration safe in a hypothermic child?
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Atrioventricular Node; Atropine; Body Temperature; Bradycar | 2006 |
Phenytoin-potentiated hepatotoxicity following acetaminophen overdose? A closer look.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Drug Overdose; Drug Synergism; Humans; Liv | 2007 |
Unusual presentation of iatrogenic phenytoin toxicity in a newborn.
Topics: Abdomen; Administration, Oral; Ampicillin; Anti-Bacterial Agents; Anticonvulsants; Cefotaxime; Drug | 2005 |
Characterization of 4-aminopyridine in overdose.
Topics: 4-Aminopyridine; Adult; Drug Overdose; Female; Humans; Middle Aged; Multiple Sclerosis; Phenytoin | 1994 |
Phenytoin overdosage and cerebellar atrophy in epileptic patients: clinical and MRI findings.
Topics: Adult; Atrophy; Cerebellar Diseases; Cerebellum; Drug Overdose; Epilepsy; Female; Humans; Magnetic R | 1994 |
Electrocardiogram showing changes consistent with desipramine overdose.
Topics: Desipramine; Drug Overdose; Emergencies; Heart; Humans; Phenytoin; Physostigmine | 1994 |
A graphical nomogram method for predicting toxic concentrations of unbound phenytoin.
Topics: Adult; Drug Overdose; Humans; Middle Aged; Phenytoin; Predictive Value of Tests; Protein Binding; Se | 1994 |
Treatment of high-dose intrathecal morphine overdose. Case report.
Topics: Drug Overdose; Female; Humans; Infusion Pumps; Injections, Spinal; Middle Aged; Morphine; Naloxone; | 1994 |
Fatality secondary to massive overdose of dimenhydrinate.
Topics: Adult; Arrhythmias, Cardiac; Cardiopulmonary Resuscitation; Charcoal; Colon; Dimenhydrinate; Diphenh | 1993 |
Magnetic resonance volumetry of the cerebellum in epileptic patients after phenytoin overdosages.
Topics: Adult; Cerebellum; Drug Overdose; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Male; Middle | 1996 |
Colonic absorption of antiepileptic agents.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biological Transport; Chromatography, High Pressure Liqu | 1997 |
Cerebellar atrophy after acute phenytoin intoxication.
Topics: Acute Disease; Adult; Atrophy; Cerebellar Diseases; Cerebellum; Drug Overdose; Humans; Magnetic Reso | 1997 |
Charcoal hemoperfusion in the treatment of phenytoin overdose.
Topics: Adult; Charcoal; Drug Overdose; Female; Hemoperfusion; Humans; Phenytoin; Poisoning | 2000 |
Elimination of phenytoin in toxic overdose.
Topics: Adult; Aged; Anticonvulsants; Drug Overdose; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; | 2000 |
An unresponsive patient with a history of stroke.
Topics: Aged; Anticonvulsants; Diagnosis, Differential; Drug Overdose; Epilepsy; Female; Humans; Phenytoin; | 1999 |
Purple glove syndrome caused by oral administration of phenytoin.
Topics: Administration, Oral; Anticonvulsants; Child; Drug Overdose; Edema; Epilepsy; Extremities; Humans; M | 2000 |
Mephenytoin overdose--phenytoin poisoning incognito? Case report and mephenytoin/phenytoin comparison.
Topics: Adult; Drug Overdose; Female; Humans; Mephenytoin; Molecular Structure; Phenytoin | 2000 |
Severe phenytoin intoxication in a subject homozygous for CYP2C9*3.
Topics: Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Craniocerebral Trauma; Cytochrome P-450 CYP2C | 2001 |
Timely antemortem and postmortem concentrations in a fatal carbamazepine overdose.
Topics: Absorption; Adult; Amobarbital; Anticonvulsants; Carbamazepine; Drug Overdose; Fatal Outcome; Female | 2001 |
Debate over use of phenytoin.
Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Drug Overdose; Humans; Phenytoin; Poisoning; Trea | 2001 |
Index of suspicion.
Topics: Adolescent; Anticonvulsants; Ataxia; Cellulitis; Child; Child, Preschool; Creatinine; Diagnosis, Dif | 2002 |
Pharmacokinetic simulation of the effect of multiple-dose activated charcoal in phenytoin poisoning--report of two pediatric cases.
Topics: Charcoal; Child, Preschool; Drug Overdose; Humans; Male; Phenytoin | 1991 |
Severe oral phenytoin overdose does not cause cardiovascular morbidity.
Topics: Administration, Oral; Adult; Cardiovascular Diseases; Drug Overdose; Electrocardiography; Female; He | 1991 |
[Plasma separation in acute, intravenous phenytoin poisoning].
Topics: Dose-Response Relationship, Drug; Drug Overdose; Electroencephalography; Epilepsy, Tonic-Clonic; Hum | 1990 |
Multiple-dose activated charcoal in management of phenytoin overdose.
Topics: Adolescent; Charcoal; Drug Overdose; Humans; Male; Phenytoin | 1989 |