phenytoin has been researched along with Depressive Disorder, Major in 3 studies
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenytoin was the first non-sedative anticonvulsant introduced and is still the anticonvulsant most widely used worldwide in neurology." | 2.71 | Controlled double-blind trial of phenytoin vs. fluoxetine in major depressive disorder. ( Belmaker, RH; Bersudsky, Y; Nemets, B, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Narasimha, VL | 1 |
| Basavaraju, R | 1 |
| Mangalore, S | 1 |
| Mehta, UM | 1 |
| Nemets, B | 2 |
| Bersudsky, Y | 1 |
| Belmaker, RH | 2 |
| Shapira, B | 1 |
| Trachtenberg, A | 1 |
2 trials available for phenytoin and Depressive Disorder, Major
| Article | Year |
|---|---|
Controlled double-blind trial of phenytoin vs. fluoxetine in major depressive disorder.
Topics: Adult; Age of Onset; Anticonvulsants; Depressive Disorder, Major; Double-Blind Method; Drug Administ | 2005 |
Phenytoin as an augmentation for SSRI failures: a small controlled study.
Topics: Adult; Aged; Anticonvulsants; Depressive Disorder, Major; Double-Blind Method; Drug Resistance; Drug | 2006 |
1 other study available for phenytoin and Depressive Disorder, Major
| Article | Year |
|---|---|
Precuneus and psychiatric manifestations: Novel neurobiological formulations through lesion based connectivity mapping of psychopathology.
Topics: Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brain Mapping; Brai | 2019 |