phenytoin has been researched along with Dental Plaque in 41 studies
Dental Plaque: A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of folic acid (5mg/day) in combination with oral hygiene measures (group II) vis-a-vis oral hygiene measures alone (group I) in prevention of phenytoin-induced gingival overgrowth was investigated in a one-year follow-up study on sixty, 8-13-year-old epileptic children receiving phenytoin." | 9.11 | Folic acid and phenytoin induced gingival overgrowth--is there a preventive effect. ( Chawla, HS; Gauba, K; Goyal, A; Prasad, VN; Singhi, P, 2004) |
| "We investigated the relationship between phenytoin-induced gingival overgrowth (GO) and the harboring of periodontal bacteria." | 7.73 | Relationship of periodontal bacteria and Porphyromonas gingivalis fimA variations with phenytoin-induced gingival overgrowth. ( Akiyama, S; Amano, A; Kato, T; Kimura, KR; Morisaki, I; Takada, Y, 2006) |
| "Microbial flora and gingival conditions were compared between a group of patients with phenytoin-induced gingival hyperplasia as a test group, a control group of patients who were administered phenytoin without gingival hyperplasia and a blank group who took no phenytoin and no gingival hyperplasia in mentally retarded patients." | 7.72 | The subgingival microflora in phenytoin-induced gingival hyperplasia. ( Hirasawa, M; Mega, J; Sugiyama, H; Takada, K; Umezawa, K, 2003) |
| " The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene." | 7.68 | Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990) |
| "The role of folic acid (5mg/day) in combination with oral hygiene measures (group II) vis-a-vis oral hygiene measures alone (group I) in prevention of phenytoin-induced gingival overgrowth was investigated in a one-year follow-up study on sixty, 8-13-year-old epileptic children receiving phenytoin." | 5.11 | Folic acid and phenytoin induced gingival overgrowth--is there a preventive effect. ( Chawla, HS; Gauba, K; Goyal, A; Prasad, VN; Singhi, P, 2004) |
| "The purpose of this clinical study was to evaluate the effect of a 3-min daily toothbrushing with 1% chlorhexidine gluconate toothpaste on dental plaque, gingivitis and gingival hyperplasia in 30 mentally retarded epileptic children treated with phenytoin." | 5.04 | Oral use of chlorhexidine gluconate toothpaste in epileptic children. ( Bay, LM; Russell, BG, 1978) |
| "We investigated the relationship between phenytoin-induced gingival overgrowth (GO) and the harboring of periodontal bacteria." | 3.73 | Relationship of periodontal bacteria and Porphyromonas gingivalis fimA variations with phenytoin-induced gingival overgrowth. ( Akiyama, S; Amano, A; Kato, T; Kimura, KR; Morisaki, I; Takada, Y, 2006) |
| "Microbial flora and gingival conditions were compared between a group of patients with phenytoin-induced gingival hyperplasia as a test group, a control group of patients who were administered phenytoin without gingival hyperplasia and a blank group who took no phenytoin and no gingival hyperplasia in mentally retarded patients." | 3.72 | The subgingival microflora in phenytoin-induced gingival hyperplasia. ( Hirasawa, M; Mega, J; Sugiyama, H; Takada, K; Umezawa, K, 2003) |
| " The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene." | 3.68 | Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990) |
| "Thus dental plaque accumulation enhanced, but was not essential for the development of the PHT-induced gingival overgrowth." | 1.28 | Phenytoin-induced gingival overgrowth in rats infected with Streptococcus sobrinus 6715. ( Adachi, C; Hamada, S; Kato, K; Kitamura, K; Mihara, J; Morisaki, I; Sobue, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (65.85) | 18.7374 |
| 1990's | 10 (24.39) | 18.2507 |
| 2000's | 4 (9.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takada, K | 1 |
| Sugiyama, H | 1 |
| Umezawa, K | 1 |
| Mega, J | 1 |
| Hirasawa, M | 1 |
| Prasad, VN | 1 |
| Chawla, HS | 1 |
| Goyal, A | 1 |
| Gauba, K | 1 |
| Singhi, P | 1 |
| Akiyama, S | 1 |
| Amano, A | 1 |
| Kato, T | 1 |
| Takada, Y | 1 |
| Kimura, KR | 1 |
| Morisaki, I | 3 |
| Smith, QT | 3 |
| Wilson, MM | 1 |
| Germaine, GR | 1 |
| Pihlstrom, BL | 3 |
| O'Neil, TC | 1 |
| Figures, KH | 1 |
| Lundström, A | 1 |
| Eeg-Olofsson, O | 1 |
| Hamp, SE | 1 |
| Carlson, JF | 1 |
| Bastien, SA | 1 |
| Keenan, KM | 1 |
| Steinberg, SC | 1 |
| Steinberg, AD | 2 |
| Seymour, RA | 1 |
| Thomason, JM | 1 |
| Ellis, JS | 1 |
| Nishikawa, S | 1 |
| Nagata, T | 1 |
| Oka, T | 1 |
| Ishida, H | 1 |
| Ciancio, SG | 2 |
| Casetta, I | 1 |
| Granieri, E | 1 |
| Desiderá, M | 1 |
| Monetti, VC | 1 |
| Tola, MR | 1 |
| Paolino, E | 1 |
| Govoni, V | 1 |
| Calura, G | 1 |
| Hassell, TM | 1 |
| Burtner, AP | 1 |
| McNeal, D | 1 |
| Smith, RG | 1 |
| Taylor, BA | 1 |
| Staple, PH | 2 |
| Reed, MJ | 2 |
| Mashimo, PA | 2 |
| Sedransk, N | 1 |
| Umemoto, T | 1 |
| Jones, JH | 1 |
| Yamada, S | 1 |
| Sato, T | 1 |
| Miake, K | 1 |
| Church, HA | 1 |
| Dolby, AE | 1 |
| Hikima, T | 1 |
| Nakamura, Y | 1 |
| Iwakami, K | 1 |
| Miyake, T | 1 |
| Ikeda, K | 1 |
| Russell, BG | 1 |
| Bay, LM | 1 |
| Munthe-Kaas, A | 1 |
| Storhaug, K | 1 |
| Romanos, GE | 1 |
| Schröter-Kermani, C | 1 |
| Hinz, N | 1 |
| Bernimoulin, JP | 1 |
| Brown, RS | 1 |
| Beaver, WT | 1 |
| Bottomley, WK | 1 |
| Mihara, J | 1 |
| Kato, K | 1 |
| Kitamura, K | 1 |
| Adachi, C | 1 |
| Sobue, S | 1 |
| Hamada, S | 1 |
| Kinane, DF | 1 |
| Drummond, JR | 1 |
| Chisholm, DM | 1 |
| Modéer, T | 2 |
| Dahllöf, G | 2 |
| Suzuki, Y | 1 |
| Maita, E | 1 |
| Suzuki, R | 1 |
| Horiuchi, H | 1 |
| Fernandez Lorente, P | 1 |
| Hinrichs, JE | 1 |
| Bostanci, H | 1 |
| Aksoy, N | 1 |
| Aydin, N | 1 |
| Maisonneuve, C | 1 |
| Yaffe, SJ | 1 |
| Catz, CC | 1 |
| Lonberg, B | 1 |
| Korff, M | 1 |
| Mutschelknauss, R | 1 |
| Newcomb, GM | 1 |
| Polson, AM | 1 |
| Glickman, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Genes Associated With Hereditary and Drug-Induced Gingival Overgrowth[NCT00104026] | 45 participants (Actual) | Observational | 2005-02-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for phenytoin and Dental Plaque
| Article | Year |
|---|---|
The pathogenesis of drug-induced gingival overgrowth.
Topics: Adult; Age Factors; Anticonvulsants; Calcium Channel Blockers; Child; Cyclosporine; Dental Plaque; F | 1996 |
Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model.
Topics: Age Factors; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Diseas | 1996 |
Medications as risk factors for periodontal disease.
Topics: Aging; Alveolar Process; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvuls | 1996 |
Oral problems and genetic aspects of individuals with epilepsy.
Topics: Dental Care for Chronically Ill; Dental Plaque; Dental Prophylaxis; Epilepsy; Fibroblasts; Gingival | 1994 |
On the mechanism of drug-induced gingival hyperplasia.
Topics: Dental Plaque; Diltiazem; Epidermal Growth Factor; Fibroblasts; Folic Acid; Gingival Hyperplasia; Gl | 1991 |
[Dental plaque and gingival hyperplasia due to Dilantin].
Topics: Dental Plaque; Gingival Hyperplasia; Humans; Phenytoin | 1985 |
Host factors in the aetiology of periodontal disease.
Topics: Aged; Animals; Antibody Formation; Antigen-Antibody Complex; Complement System Proteins; Dental Occl | 1973 |
Periodontal disease.
Topics: Adult; Ascorbic Acid Deficiency; Bone Resorption; Child; Dental Deposits; Dental Plaque; Endotoxins; | 1971 |
3 trials available for phenytoin and Dental Plaque
| Article | Year |
|---|---|
Folic acid and phenytoin induced gingival overgrowth--is there a preventive effect.
Topics: Adolescent; Anticonvulsants; Child; Dental Plaque; Epilepsy; Folic Acid; Follow-Up Studies; Gingival | 2004 |
Phenytoin-induced gingival overgrowth: a community-based cross-sectional study in Ferrara, Italy.
Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Anticonvulsants; Child; Child, Preschool | 1997 |
Oral use of chlorhexidine gluconate toothpaste in epileptic children.
Topics: Administration, Oral; Adolescent; Biguanides; Child; Child, Preschool; Chlorhexidine; Clinical Trial | 1978 |
30 other studies available for phenytoin and Dental Plaque
| Article | Year |
|---|---|
The subgingival microflora in phenytoin-induced gingival hyperplasia.
Topics: Adolescent; Adult; Bacteria, Anaerobic; Case-Control Studies; Dental Plaque; Female; Gingival Hyperp | 2003 |
Relationship of periodontal bacteria and Porphyromonas gingivalis fimA variations with phenytoin-induced gingival overgrowth.
Topics: Adolescent; Adult; Aggregatibacter actinomycetemcomitans; Anticonvulsants; Bacteroides; Child; Denta | 2006 |
Microbial flora and clinical parameters in phenytoin associated gingival overgrowth.
Topics: Bacteria; Dental Plaque; Female; Gingival Hyperplasia; Humans; Male; Phenytoin | 1983 |
The effects of chlorhexidine and mechanical methods of plaque control on the recurrence of gingival hyperplasia in young patients taking phenytoin.
Topics: Adolescent; Adult; Chlorhexidine; Dental Care for Disabled; Dental Plaque; Female; Gingival Hyperpla | 1982 |
Effects of anti-epileptic drug treatment with carbamazepine or phenytoin on the oral state of children and adolescents.
Topics: Adolescent; Adult; Carbamazepine; Child; Dental Plaque; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clo | 1982 |
Prevention of phenytoin associated gingival enlargement--a 15-month longitudinal study.
Topics: Adolescent; Adult; Calibration; Child; Dental Plaque; Dental Prophylaxis; Female; Gingival Hyperplas | 1980 |
Phenytoin-induced gingival overgrowth control in severely retarded children.
Topics: Adolescent; Child; Child, Preschool; Dental Plaque; Gingiva; Gingival Hyperplasia; Humans; Intellect | 1982 |
Management of drug-induced gingival enlargement with orthodontic complications.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Esthetics, Dental; Feeding a | 2000 |
Diphenylhydantoin gingival hyperplasia in Macaca arctoides: prevention by inhibition of dental plaque deposition.
Topics: Actinomyces; Administration, Topical; Animals; Bacteria; Biguanides; Chlorhexidine; Dental Plaque; F | 1978 |
Healthy and diseased gingiva.
Topics: Adult; Child; Chronic Disease; Dental Plaque; Diabetes Complications; Gingiva; Gingival Diseases; Gi | 1975 |
Experimental pathological studies on dilantin gingival hyperplasia in rat. (I) Macroscopical and light-microscopical observations.
Topics: Animals; Dental Plaque; Gingival Hyperplasia; Inflammation; Microscopy; Phenytoin; Rats | 1977 |
The effect of dilantin on the cellular immune response to dento-gingival plaque extract.
Topics: Adult; Dental Plaque; DNA; Female; Fetal Blood; Humans; Immune Sera; Immunity, Cellular; Lymphocyte | 1978 |
[A case of dilantin hyperplasia (author's transl)].
Topics: Adult; Dental Plaque; Denture, Partial, Removable; Gingival Hyperplasia; Gingivectomy; Humans; Male; | 1977 |
Diphenylhydantoin gingival hyperplasia in Macaca arctoides: a new human model.
Topics: Adult; Animals; Dental Plaque; Disease Models, Animal; Female; Gingiva; Gingival Hyperplasia; Gingiv | 1977 |
[Tooth health, drugs, and gingival hyperplasia].
Topics: Adolescent; Child; Child, Preschool; Chlorhexidine; Dental Plaque; Gingival Hyperplasia; Humans; Ora | 1978 |
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia.
Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque; | 1992 |
Prevention and treatment of Dilantin-associated gingival enlargement.
Topics: Adult; Dental Plaque; Dental Scaling; Gingival Hyperplasia; Gingivectomy; Humans; Male; Oral Hygiene | 1990 |
Phenytoin-induced gingival overgrowth in rats infected with Streptococcus sobrinus 6715.
Topics: Animals; Dental Plaque; Dental Plaque Index; Diet, Cariogenic; Gingival Hyperplasia; Male; Phenytoin | 1990 |
Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia.
Topics: Adult; Cell Count; Chronic Disease; Dental Plaque; Gingival Hyperplasia; Gingivitis; Humans; Langerh | 1990 |
Development of phenytoin-induced gingival overgrowth in non-institutionalized epileptic children subjected to different plaque control programs.
Topics: Adolescent; Child; Dental Care for Disabled; Dental Plaque; Dental Plaque Index; Epilepsy; Female; G | 1987 |
The effect of a plaque control program on the development of phenytoin-induced gingival overgrowth. A 2-year longitudinal study.
Topics: Adolescent; Child; Dental Plaque; Dental Prophylaxis; Female; Gingival Hyperplasia; Gingivitis; Huma | 1986 |
[Clinical study of gingival hyperplasia caused by diphenylhydantoin].
Topics: Adolescent; Adult; Child; Dental Plaque; Gingival Hyperplasia; Humans; Periodontal Diseases; Phenyto | 1986 |
[Hydantoin gingival hyperplasia].
Topics: Adolescent; Adult; Child; Chlorhexidine; Dental Plaque; Female; Gingival Hyperplasia; Gingivectomy; | 1986 |
Phenytoin and 5-(p-hydroxyphenyl)-5-phenylhydantoin do not alter the effects of bacterial and amplified plaque extracts on cultures of fibroblasts from normal and overgrown gingivae.
Topics: Actinomyces; Adult; Bacterial Physiological Phenomena; Cell Count; Cell Division; Cells, Cultured; D | 1987 |
[Phenytoin and gingival hyperplasia].
Topics: Adolescent; Adult; Child; Dental Plaque; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Ph | 1987 |
Office management of phenytoin-induced gingival overgrowth.
Topics: Chlorhexidine; Dental Plaque; Dental Prophylaxis; Gingival Hyperplasia; Humans; Phenytoin | 1985 |
Gingival hyperplasia and diphenylhydantoin.
Topics: Child; Dental Plaque; Gingival Hyperplasia; Humans; Oral Health; Phenytoin; Saliva | 1972 |
[Epileptic children as patients in a systematic school dental service].
Topics: Adolescent; Anticonvulsants; Child; Dental Plaque; Epilepsy; Female; Gingiva; Gingival Hyperplasia; | 1973 |
[Hydantoin-induced hyperplasia].
Topics: Adolescent; Adult; Child; Dental Plaque; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Human | 1973 |
Gingival and periodontal problems in children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Dental Plaque; Gingival Hyperplasia; Gin | 1974 |