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phenytoin and Deficiency, Vitamin D

phenytoin has been researched along with Deficiency, Vitamin D in 27 studies

Research Excerpts

ExcerptRelevanceReference
" She was receiving phenytoin for epilepsy for 2 years."7.76Phenytoin induced vitamin D deficiency presenting as proximal muscle weakness. ( Aggarwal, A; Faridi, MM, 2010)
" She was receiving phenytoin for epilepsy for 2 years."3.76Phenytoin induced vitamin D deficiency presenting as proximal muscle weakness. ( Aggarwal, A; Faridi, MM, 2010)
"To report a case of loss of seizure control due to hypocalcemia resulting from long-term treatment with phenytoin and phenobarbital."3.72Loss of seizure control due to anticonvulsant-induced hypocalcemia. ( Al-Busairi, WA; Al-Bustan, MA; Al-Mulla, FA; Ali, FE, 2004)
"Phenytoin is a highly effective anticonvulsant medication that is considered to be the treatment of choice for generalized major motor and focal epileptic seizures."3.66Phenytoin: pharmacokinetics and clinical therapeutics. ( Finn, AL; Olanow, CW, 1981)
" Soon after the drug was introduced into clinical practice, gingival enlargement was noticed as a side effect and, despite much research effort, the etiology of this condition remains unknown."2.36Side effects of diphenylhydantoin: a review. ( Keith, DA, 1978)
" Hypocalcaemia was related to high dosage of anticonvulsant drugs, to multiple drug therapy, and to the use of individual anticonvulsant drugs in the following order, with decreasing order of importance: pheneturide, primidone, phenytoin, phenobarbitone."1.25Disturbance of calcium metabolism by anticonvulsant drugs. ( Richens, A; Rowe, DJ, 1970)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199019 (70.37)18.7374
1990's2 (7.41)18.2507
2000's4 (14.81)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nseir, G1
Golshayan, D1
Barbey, F1
Kashyap, AS1
Anand, KP1
Kashyap, S1
Faridi, MM1
Aggarwal, A1
Ali, FE1
Al-Bustan, MA1
Al-Busairi, WA1
Al-Mulla, FA1
Seymour, HM1
Glendenning, P1
Karceski, SC1
Olanow, CW1
Finn, AL1
De Wolff, FA1
Broadus, AE1
Hanson, TA1
Bartter, FC1
Walton, J1
Keith, DA1
Gascon-Barré, M1
Côte, MG1
Brodeur, J1
Robinson, PB1
Rowe, DJ2
Harris, M1
Gascon Barré, M1
Fehlinger, R1
Seidel, K1
Hosking, DJ1
Williams, A1
Godwin-Austen, RB1
Allison, SP1
Bouillon, R1
Reynaert, J1
Claes, JH1
Lissens, W1
De Moor, P1
Petrides, PE1
Bartl, R1
Büchele, W1
Moser, E1
Ronin, DI1
Wu, YC1
Sahgal, V1
MacLean, IC1
Silver, J1
Davies, TJ1
Kupersmitt, E1
Orme, M1
Petrie, A1
Vajda, F1
Villareale, M1
Gould, LV1
Wasserman, RH1
Barr, A1
Chiroff, RT1
Bergstrom, WH1
Schaefer, K2
von Herrath, D2
Kraft, D2
Reynolds, EH1
Koch, HU1
Varkey, K1
Raman, PT1
Bhaktaviziam, A1
Taori, GM1
Genuth, SM1
Klein, L1
Rabinovich, S1
King, KC1
Richens, A1

Reviews

4 reviews available for phenytoin and Deficiency, Vitamin D

ArticleYear
Side effects of diphenylhydantoin: a review.
    Journal of oral surgery (American Dental Association : 1965), 1978, Volume: 36, Issue:3

    Topics: Animals; Anticonvulsants; Culture Techniques; Fibroblasts; Forecasting; Gingiva; Gingival Hypertroph

1978
[Vitamin D: influence of anticonvulsant drugs on its metabolism].
    L'union medicale du Canada, 1977, Volume: 106, Issue:5

    Topics: Animals; Anticonvulsants; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; Hydroxylation;

1977
[Critical remarks on the concept of "osteopathia antiepileptica"].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1976, Volume: 28, Issue:9

    Topics: Anticonvulsants; Bone Resorption; Calcium; Epilepsy; Humans; Osteomalacia; Phenytoin; Tetany; Vitami

1976
Disordered calcium metabolism during anticonvulsant treatment.
    German medicine, 1973,Winter, Volume: 3, Issue:3-4

    Topics: Adolescent; Animals; Anticonvulsants; Biliary Tract; Bone Diseases; Calcium; Child; Cholecalciferol;

1973

Other Studies

23 other studies available for phenytoin and Deficiency, Vitamin D

ArticleYear
Phenytoin-associated severe hypocalcemia with seizures in a patient with a TSC2-PKD1 contiguous gene syndrome.
    Renal failure, 2013, Volume: 35, Issue:6

    Topics: Adult; Anticonvulsants; Humans; Hypocalcemia; Male; Phenytoin; Renal Insufficiency, Chronic; Syndrom

2013
Case 3-2009: a 9-month-old boy with seizures.
    The New England journal of medicine, 2009, Apr-09, Volume: 360, Issue:15

    Topics: Anticonvulsants; Humans; Hypocalcemia; Infant; Male; Phenytoin; Seizures; Vitamin D; Vitamin D Defic

2009
Phenytoin induced vitamin D deficiency presenting as proximal muscle weakness.
    Indian pediatrics, 2010, Volume: 47, Issue:7

    Topics: Child; Epilepsy; Female; Gait; Humans; Hyperparathyroidism, Secondary; Muscle Weakness; Phenytoin; V

2010
Loss of seizure control due to anticonvulsant-induced hypocalcemia.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:6

    Topics: Adult; Anticonvulsants; Humans; Hypocalcemia; Male; Phenobarbital; Phenytoin; Seizures; Vitamin D De

2004
Fit for a fracture.
    The Medical journal of Australia, 2005, Aug-15, Volume: 183, Issue:4

    Topics: Anticonvulsants; Epilepsy; Ergocalciferols; Female; Femoral Neck Fractures; Follow-Up Studies; Fract

2005
Bone health.
    Neurology, 2008, Apr-29, Volume: 70, Issue:18

    Topics: Adult; Anticonvulsants; Bone Diseases, Metabolic; Epilepsy; Female; Humans; Patient Dropouts; Phenyt

2008
Phenytoin: pharmacokinetics and clinical therapeutics.
    Neurosurgery, 1981, Volume: 8, Issue:1

    Topics: Abnormalities, Drug-Induced; Biological Availability; Drug Interactions; Humans; Kidney Diseases; Li

1981
Stimulation of vitamin D-dependent Ca-ATPase and of intestinal caldium absorption by diphenylhydantoin.
    European journal of pharmacology, 1975, Volume: 33, Issue:1

    Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Calcium; In Vitro Techniques; Intestinal A

1975
Primary hyperparathyroidism presenting as anticonvulsant-induced osteomalacia.
    The American journal of medicine, 1977, Volume: 63, Issue:2

    Topics: Adenoma; Adult; Antigens; Calcium; Cyclic AMP; Diagnosis, Differential; Female; Humans; Hyperparathy

1977
Hepatic drug metabolism after phenobarbital and diphenylhydantoin administration in the rat--influence of vitamin D3 status.
    Biochemical pharmacology, 1979, Volume: 28, Issue:2

    Topics: Animals; Calcium; Cholecalciferol; Hexobarbital; Liver; Male; Mixed Function Oxygenases; Pharmaceuti

1979
The effects of diphenylhydantoin and vitamin D deficiency on developing teeth in the rat.
    Archives of oral biology, 1978, Volume: 23, Issue:3

    Topics: Animals; Body Weight; Odontometry; Phenytoin; Rats; Time Factors; Tooth; Vitamin D Deficiency

1978
Osteomalacia presenting as chorea.
    British medical journal, 1975, Jul-19, Volume: 3, Issue:5976

    Topics: Adolescent; Alkaline Phosphatase; Chorea; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Humans; H

1975
Vitamin D supplements: requirements in special circumstances in children.
    Canadian Medical Association journal, 1975, May-17, Volume: 112, Issue:10

    Topics: Animals; Barbiturates; Birth Weight; Canada; Cattle; Child; Humans; Infant, Newborn; Nutritional Req

1975
The effect of anticonvulsant therapy on serum levels of 25-hydroxy-vitamin D, calcium, and parathyroid hormone.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:06

    Topics: Calcium; Cholesterol; Epilepsy; Female; Humans; Hyperparathyroidism, Secondary; Hypocalcemia; Parath

1975
[Chief symptoms: bone pain and muscle weakness].
    Der Internist, 1991, Volume: 32, Issue:1

    Topics: Aged; Alkaline Phosphatase; Biopsy; Bone and Bones; Diagnosis, Differential; Epilepsy, Absence; Fema

1991
Intractable muscle pain syndrome, osteomalacia, and axonopathy in long-term use of phenytoin.
    Archives of physical medicine and rehabilitation, 1991, Volume: 72, Issue:10

    Topics: Aged; Humans; Male; Muscular Diseases; Nervous System Diseases; Osteomalacia; Pain; Phenytoin; Vitam

1991
Prevalence and treatment of vitamin D deficiency in children on anticonvulsant drugs.
    Archives of disease in childhood, 1974, Volume: 49, Issue:5

    Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Cholecalciferol; Diet; Enzyme Induction;

1974
Diphenylhydantoin: effects on calcium metabolism in the chick.
    Science (New York, N.Y.), 1974, Feb-15, Volume: 183, Issue:4125

    Topics: Animals; Body Weight; Bone and Bones; Calcium; Calcium Radioisotopes; Chickens; Cholecalciferol; Dos

1974
Iatrogenic nutritional effects of anticonvulsants.
    The Proceedings of the Nutrition Society, 1974, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Blood Coagulation Disorders; Bone Diseases; Child; Child, Presch

1974
Influence of diphenylhydantoin and phenobarbital on intestinal calcium transport in the rat.
    Epilepsia, 1972, Volume: 13, Issue:6

    Topics: Animals; Binding, Competitive; Calcium; Calcium Isotopes; Calcium Metabolism Disorders; Epilepsy; In

1972
Osteomalacia due to phenytoin sodium. A case report with review of literature.
    Journal of the neurological sciences, 1973, Volume: 19, Issue:3

    Topics: Adult; Bone and Bones; Calcium; Carbamazepine; Clavicle; Deficiency Diseases; Female; Folic Acid; Hu

1973
Osteomalacia accompanying chronic anticonvulsant therapy.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 35, Issue:3

    Topics: Adolescent; Alkaline Phosphatase; Biopsy; Bone and Bones; Calcium; Epilepsy; Humans; Hydroxyproline;

1972
Disturbance of calcium metabolism by anticonvulsant drugs.
    British medical journal, 1970, Oct-10, Volume: 4, Issue:5727

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Calcium Metabolism Disorders; Enzyme

1970