phenytoin has been researched along with Deficiency, Mental in 112 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty severely retarded institutionalized epileptic adults with phenytoin-induced gingival hyperplasia were divided into two groups and received a daily 3 mg capsule of either folic acid or lactose for 16 weeks in a randomized, double-blind, parallel study." | 9.07 | The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study. ( Beaver, WT; Bottomley, WK; Brown, RS; Di Stanislao, PT, 1991) |
| "A 28-year-old male developed total external ophthalmoplegia following oral administration of phenytoin." | 7.72 | Total external ophthalmoplegia induced by phenytoin: a case report and review of literature. ( Chaudhry, N; Puri, V, 2004) |
| "The relationship among the serum concentration of phenytoin, pneumoencephalographic measurements describing, in particular, cerebellar atrophy, and various other clinical variables was analyzed statistically in a series of 131 phenytoin-treated mentally retarded epileptics." | 7.65 | Cerebellar atrophy in phenytoin-treated mentally retarded epileptics. ( Helle, EP; Iivanainen, M; Viukari, M, 1977) |
| " The long-term use of phenytoin is not recommended for patients with loss of locomotion, marked cognitive impairment, or symptoms and signs of cerebellar disease." | 6.40 | Phenytoin: effective but insidious therapy for epilepsy in people with intellectual disability. ( Iivanainen, M, 1998) |
| "Twenty severely retarded institutionalized epileptic adults with phenytoin-induced gingival hyperplasia were divided into two groups and received a daily 3 mg capsule of either folic acid or lactose for 16 weeks in a randomized, double-blind, parallel study." | 5.07 | The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study. ( Beaver, WT; Bottomley, WK; Brown, RS; Di Stanislao, PT, 1991) |
| "It has recently been reported that folic acid supplementation reduced DPH-induced gingival hyperplasia in cat and in a pilot study also in man." | 5.06 | Folate treatment of diphenylhydantoin-induced gingival hyperplasia. ( Bäckman, N; Blomquist, HK; Hänström, L; Heijbel, J; Holm, AK; Säfström, G, 1989) |
| "The purpose of this clinical study was to evaluate the effect of a 3-min daily toothbrushing with 1% chlorhexidine gluconate toothpaste on dental plaque, gingivitis and gingival hyperplasia in 30 mentally retarded epileptic children treated with phenytoin." | 5.04 | Oral use of chlorhexidine gluconate toothpaste in epileptic children. ( Bay, LM; Russell, BG, 1978) |
| "A 28-year-old male developed total external ophthalmoplegia following oral administration of phenytoin." | 3.72 | Total external ophthalmoplegia induced by phenytoin: a case report and review of literature. ( Chaudhry, N; Puri, V, 2004) |
| " Following treatment with antiepileptic drugs (AEDs), the patient developed several rare complications: after beginning therapy with phenytoin, the patient developed pseudolymphoma; after monotherapy with carbamazepine (CBZ), the patient thereafter developed myoclonic jerks of upper and lower limbs upon awakening; after one year of treatment with valproate (VPA) the patient developed clinical and immuno-haematological signs of SLE." | 3.69 | Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p. ( Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G, 1996) |
| "The case of a mentally handicapped female patient is presented who developed typical pellagra with dermatitis, diarrhoea and mental alteration following a long-term antiepileptic treatment with phenytoin, ethosuximide and valproic acid." | 3.68 | [Pellagra in anticonvulsive therapy]. ( Bartels, H; Hebestreit, H; Mingers, AM; Pannenbecker, J, 1990) |
| "In a cross-sectional, epidemiological study of phenytoin induced gingival overgrowth in 77 institutionalized persons with epilepsy, the severity of the gum lesions was quantified by means of a precise new technique." | 3.67 | Phenytoin induced gingival overgrowth in institutionalized epileptics. ( Best, H; Hassell, T; Murphy, T; O'Donnell, J; Pearlman, J; Tesini, D, 1984) |
| "The relationship among the serum concentration of phenytoin, pneumoencephalographic measurements describing, in particular, cerebellar atrophy, and various other clinical variables was analyzed statistically in a series of 131 phenytoin-treated mentally retarded epileptics." | 3.65 | Cerebellar atrophy in phenytoin-treated mentally retarded epileptics. ( Helle, EP; Iivanainen, M; Viukari, M, 1977) |
| " The long-term use of phenytoin is not recommended for patients with loss of locomotion, marked cognitive impairment, or symptoms and signs of cerebellar disease." | 2.40 | Phenytoin: effective but insidious therapy for epilepsy in people with intellectual disability. ( Iivanainen, M, 1998) |
| "The prevalence of unrecognized primary hypothyroidism and hyperthyroidism was 5·2% and 2·8%, respectively." | 1.37 | Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study. ( de Rijke, YB; van Toor, H; Visser, TJ; Visser, WE, 2011) |
| " Since phenytoin has a narrow therapeutic index and genotyping may be carried out rapidly and at low cost, dosage adjustment based on CYP2C9 genotype, especially at the induction of therapy, would be of value in order to lower the risk of concentration dependent drug intoxications in carriers." | 1.31 | The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement. ( de Haan, K; Steijns, LS; van der Weide, J; van Weelden, MJ, 2001) |
| "She had growth retardation, mental deficiency, craniofacial dysmorphism and iris colomobata specific to FHS." | 1.30 | Polydactyly and fetal hydantoin syndrome: an additional component of the syndrome? ( Cenani, A; Somay, G; Tüysüz, B; Yalçinkaya, C, 1997) |
| "Authors report about a boy with Rasmussen syndrome." | 1.29 | [Rasmussen syndrome]. ( Lombay, B; Velkey, I, 1993) |
| "2) Most local gingival recessions were found on the labial gingiva of the mandibular anterior teeth." | 1.28 | [Oral findings in severely handicapped patients participating in the periodic dental check-up system for five years--dental caries, gingival recessions and hyperplasias, periodontal diseases]. ( Hiraide, Y; Hosaka, K; Itou, A; Kasahara, H; Kawashima, S; Nohara, S; Ogasawara, T; Watanabe, T, 1990) |
| "Most patients have quiescent seizure disorders and can manage well on monotherapy." | 1.27 | Reduction of polypharmacy for epilepsy in an institution for the retarded. ( Bennett, HS; Dunlop, T; Ziring, P, 1983) |
| " Data were excluded for patients who required dosage adjustments because of toxicity or seizures." | 1.27 | Effect of influenza vaccine on serum anticonvulsant concentrations. ( Fidone, GS; Jann, MW, 1986) |
| "Hyperthyroidism was found in 3/402 (0." | 1.26 | The prevalence of thyroid dysfunction in mentally handicapped in-patients. ( Cameron, J; Goonetilleke, AS; Hughes, VC, 1982) |
| "The fetal hydantoin syndrome is a variable pattern of altered growth (pre and postnatal), mental deficiency, unusual facies, distal phalangeal hypoplasia, and other defects occurring in some infants exposed in utero to hydantoins." | 1.26 | [The fetal hydantoin syndrome (author's transl)]. ( Cabezuelo-Huerta, G; Frontera-Izquierdo, P; Mulas, F, 1981) |
| "Hirsutism was rare in black patients." | 1.26 | Effects of diphenylhydantoin in 41 epileptics institutionalized since childhood. ( Herberg, KP, 1977) |
| "Two cases of hemophilia in severely mentally retarded patients with drug-induced gingival hyperplasia are presented." | 1.26 | The management of drug induced gingival hyperplasia in mentally retarded patients with hemophilia: a report of two cases. ( Clark, A; Murphy, JB; Nersasian, R, 1978) |
| " Monitoring drug levels and electroencephalograms appears to be the method of choice for ensuring safe and effective medication in intractable epilepsy." | 1.26 | Electroencephalography and phenytoin toxicity in mentally retarded epileptic patients. ( Helle, EP; Iivanainen, M; Seppäläinen, AM; Viukari, M, 1978) |
| "Phenytoin is a central anticholinergic agent and a central stimulant of serotonin, and may induce movement disorders as a result of altering these neurotransmitters in the brain." | 1.26 | Phenytoin-induced dystonia and choreoathetosis in two retarded epileptic children. ( Chalhub, EG; Devivo, DC; Volpe, JJ, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 89 (79.46) | 18.7374 |
| 1990's | 10 (8.93) | 18.2507 |
| 2000's | 6 (5.36) | 29.6817 |
| 2010's | 6 (5.36) | 24.3611 |
| 2020's | 1 (0.89) | 2.80 |
| Authors | Studies |
|---|---|
| Lhamu, T | 1 |
| Sadh, K | 1 |
| Dahale, AB | 1 |
| Mohan, V | 1 |
| Loganathan, S | 1 |
| Ortiz-Madinaveitia, S | 1 |
| Serrano-Madrid, ML | 1 |
| Conejo-Moreno, D | 1 |
| Sagarra-Mur, D | 1 |
| Jimenez-Corral, C | 1 |
| Gutierrez-Alvarez, AM | 1 |
| Coffey, MJ | 1 |
| Maeda, S | 1 |
| Tomoyasu, Y | 1 |
| Higuchi, H | 1 |
| Ishii-Maruhama, M | 1 |
| Egusa, M | 1 |
| Miyawaki, T | 1 |
| Kira, S | 1 |
| Visser, WE | 1 |
| de Rijke, YB | 1 |
| van Toor, H | 1 |
| Visser, TJ | 1 |
| Chaudhary, SC | 1 |
| Sonkar, SK | 1 |
| Kumar, V | 1 |
| Golchha, S | 1 |
| Premachandra, BN | 1 |
| Radparvar, A | 1 |
| Burman, K | 1 |
| Williams, IK | 1 |
| BUTTERWORTH, T | 2 |
| STREAN, LP | 1 |
| NELSON, CT | 1 |
| GROVES, R | 1 |
| SCHLOESSER, PT | 1 |
| WILSKE, KR | 1 |
| SHALIT, IE | 1 |
| WILLKENS, RF | 1 |
| DECKER, JL | 1 |
| SNYDER, CH | 1 |
| Puri, V | 1 |
| Chaudhry, N | 1 |
| Margari, L | 1 |
| Lucia, M | 1 |
| Presicci, A | 1 |
| Anna, P | 1 |
| Ventura, P | 1 |
| Patrizia, V | 1 |
| Buttiglione, M | 1 |
| Maura, B | 1 |
| Andreula, C | 1 |
| Cosma, A | 1 |
| Perniola, T | 1 |
| Tommaso, P | 1 |
| Sonohata, M | 1 |
| Asami, A | 1 |
| Tsunoda, K | 1 |
| Hotokebuchi, T | 1 |
| Caselli, R | 1 |
| Mencarelli, MA | 1 |
| Papa, FT | 1 |
| Ariani, F | 1 |
| Longo, I | 1 |
| Meloni, I | 1 |
| Vonella, G | 1 |
| Acampa, M | 1 |
| Auteri, A | 1 |
| Vicari, S | 1 |
| Orsi, A | 1 |
| Hayek, G | 1 |
| Renieri, A | 1 |
| Mari, F | 1 |
| Hughes, VC | 1 |
| Cameron, J | 1 |
| Goonetilleke, AS | 1 |
| Postellon, DC | 1 |
| Russell, BG | 2 |
| Bay, LM | 2 |
| Hassell, T | 2 |
| O'Donnell, J | 2 |
| Pearlman, J | 2 |
| Tesini, D | 2 |
| Murphy, T | 2 |
| Best, H | 2 |
| Bennett, HS | 1 |
| Dunlop, T | 1 |
| Ziring, P | 1 |
| Linnoila, M | 1 |
| Viukari, M | 3 |
| Vaisanen, K | 1 |
| Auvinen, J | 1 |
| Girgis, SS | 1 |
| Staple, PH | 1 |
| Miller, WA | 1 |
| Sedransk, N | 1 |
| Thompson, T | 1 |
| Steinberg, SC | 1 |
| Steinberg, AD | 1 |
| Davis, VJ | 2 |
| Schroeder, SR | 1 |
| Kanoy, RC | 1 |
| Mulick, JA | 1 |
| Rojahn, J | 1 |
| Thios, SJ | 1 |
| Stephens, M | 1 |
| Hawk, B | 1 |
| Lorente, CA | 1 |
| Tassinari, MS | 1 |
| Keith, DA | 1 |
| Frontera-Izquierdo, P | 1 |
| Cabezuelo-Huerta, G | 1 |
| Mulas, F | 1 |
| Poling, AD | 1 |
| Wysocki, T | 1 |
| Breuning, SE | 1 |
| Branford, D | 1 |
| Collacott, RA | 1 |
| Velkey, I | 1 |
| Lombay, B | 1 |
| Roed-Petersen, B | 1 |
| Gigli, GL | 1 |
| Scalise, A | 1 |
| Silvestri, G | 1 |
| Diomedi, M | 1 |
| Placidi, F | 1 |
| Pomponi, MG | 1 |
| Masala, C | 1 |
| Yalçinkaya, C | 1 |
| Tüysüz, B | 1 |
| Somay, G | 1 |
| Cenani, A | 1 |
| Iivanainen, M | 4 |
| Kobayashi, Y | 1 |
| Yoshino, A | 1 |
| van der Weide, J | 1 |
| Steijns, LS | 1 |
| van Weelden, MJ | 1 |
| de Haan, K | 1 |
| Herberg, KP | 1 |
| Murphy, JB | 1 |
| Nersasian, R | 1 |
| Clark, A | 1 |
| Knuutila, S | 1 |
| Siimes, M | 1 |
| Simell, O | 1 |
| Tammisto, P | 5 |
| Weber, T | 1 |
| Livingston, S | 1 |
| Pauli, LL | 1 |
| Pruce, I | 1 |
| Kramer, II | 1 |
| Meistrup-Larsen, KI | 1 |
| Hermann, S | 1 |
| Permin, H | 1 |
| Char, F | 1 |
| Hearty, JB | 1 |
| Dungan, WT | 1 |
| Schain, RJ | 1 |
| Seppäläinen, AM | 1 |
| Helle, EP | 2 |
| Janz, D | 1 |
| Maclay, E | 1 |
| Hadden, DR | 1 |
| McIlrath, EM | 1 |
| Nesbitt, GS | 1 |
| Jubiz, W | 1 |
| Haussler, MR | 1 |
| McCain, TA | 1 |
| Tolman, KG | 1 |
| Vose, GP | 1 |
| Rawley, R | 1 |
| Ashby, J | 1 |
| Chalhub, EG | 1 |
| Devivo, DC | 1 |
| Volpe, JJ | 1 |
| Oettinger, B | 1 |
| Van Buren, JM | 1 |
| Ajmone-Marsan, C | 1 |
| Mutsuga, N | 1 |
| Sadowsky, D | 1 |
| Barden, HS | 1 |
| Smith, E | 1 |
| Curtis, JL | 1 |
| Swicord, W | 1 |
| Brown, RS | 1 |
| Di Stanislao, PT | 1 |
| Beaver, WT | 1 |
| Bottomley, WK | 1 |
| Hebestreit, H | 1 |
| Pannenbecker, J | 1 |
| Mingers, AM | 1 |
| Bartels, H | 1 |
| Ogasawara, T | 1 |
| Kasahara, H | 1 |
| Hosaka, K | 1 |
| Itou, A | 1 |
| Nohara, S | 1 |
| Hiraide, Y | 1 |
| Kawashima, S | 1 |
| Watanabe, T | 1 |
| Bäckman, N | 1 |
| Holm, AK | 1 |
| Hänström, L | 1 |
| Blomquist, HK | 1 |
| Heijbel, J | 1 |
| Säfström, G | 1 |
| Aman, MG | 2 |
| Singh, NN | 1 |
| Sheppard, LC | 1 |
| Ballinger, BR | 1 |
| Fenton, GW | 1 |
| Poppell, TD | 1 |
| Burtner, AP | 1 |
| Deb, S | 1 |
| Cowie, VA | 1 |
| Richens, A | 1 |
| Bhatia, MS | 1 |
| Singhal, PK | 1 |
| Kaur, N | 1 |
| Paxton, JW | 1 |
| Field, CJ | 1 |
| Foote, SE | 1 |
| Jann, MW | 1 |
| Fidone, GS | 1 |
| Agran, M | 1 |
| Martin, JE | 1 |
| Sandman, CA | 1 |
| Barron, JL | 1 |
| Parker, L | 1 |
| Royer, P | 1 |
| Lennox-Buchthal, MA | 1 |
| Arakawa, T | 2 |
| Afifi, AK | 1 |
| Van Allen, MW | 1 |
| Tchicaloff, M | 1 |
| McKinney, W | 1 |
| McGreal, DA | 1 |
| Liu, MC | 1 |
| Griffiths, WC | 1 |
| Diamond, I | 1 |
| Annegers, JF | 1 |
| Elveback, LR | 1 |
| Hauser, WA | 1 |
| Kurland, LT | 1 |
| Eeg-Olofsson, O | 1 |
| Gertenrich, RL | 1 |
| Brown, CA | 1 |
| Rundle, AT | 1 |
| Clothier, B | 1 |
| Sudell, B | 1 |
| Yoshida, T | 1 |
| Honda, Y | 1 |
| Narisawa, K | 1 |
| Hirono, H | 1 |
| Lifshitz, F | 1 |
| Maclaren, NK | 1 |
| Schlack, HG | 1 |
| Vogt, HJ | 1 |
| Partington, MW | 1 |
| Tu, JB | 1 |
| Wong, CY | 1 |
| Vallarta, JM | 1 |
| Bell, DB | 1 |
| Reichert, A | 1 |
| Goldberg, JB | 1 |
| Kurland, AA | 1 |
| Lipman, RS | 1 |
| Babcock, JR | 1 |
| Commiskey, LV | 1 |
| White, GO | 1 |
| Viukari, NM | 6 |
| Soyka, LF | 1 |
| Moe, PJ | 1 |
| Wefring, KW | 1 |
| Houben, PF | 1 |
| Hommes, OR | 1 |
| Knaven, PJ | 1 |
| Logan, WJ | 1 |
| Freeman, JM | 1 |
| Matti, N | 1 |
| Viukari, A | 1 |
| Edmundson, WF | 1 |
| Davies, JE | 1 |
| Maceo, A | 1 |
| Morgade, C | 1 |
| Kalensky, J | 1 |
| Herzka, HS | 1 |
| Gillen, HW | 1 |
| Pippinger, CE | 1 |
| Meeuwisse, G | 1 |
| Gamstorp, I | 1 |
| Tryding, N | 1 |
| Reynolds, EH | 1 |
| Buchanan, RA | 2 |
| Heffelfinger, JC | 2 |
| Weiss, CF | 2 |
7 reviews available for phenytoin and Deficiency, Mental
| Article | Year |
|---|---|
Diagnosis and treatment of congenital hypothyroidism.
Topics: Cholestyramine Resin; Congenital Hypothyroidism; Drug Interactions; Female; Humans; Hypothyroidism; | 1983 |
Phenytoin: effective but insidious therapy for epilepsy in people with intellectual disability.
Topics: Anticonvulsants; Brain; Dose-Response Relationship, Drug; Epilepsy; Humans; Intellectual Disability; | 1998 |
Febrile convulsions: diagnosis, treatment, and prognosis.
Topics: Child; Epilepsy; Humans; Infant; Intellectual Disability; Intelligence; Meningitis; Phenobarbital; P | 1979 |
Establishing socially validated drug research in community settings.
Topics: Anticonvulsants; Behavior; Community Mental Health Services; Humans; Intellectual Disability; Phenyt | 1985 |
Febrile convulsions. A reappraisal.
Topics: Age Factors; Animals; Animals, Newborn; Body Temperature; Brain; Brain Damage, Chronic; Child, Presc | 1973 |
Congenital and acquired disturbances of histidine metabolism.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Animals; Biopsy; Carbon Radioisotopes; Chil | 1974 |
Pharmacotherapy of children.
Topics: Antidepressive Agents; Bibliographies as Topic; Brain Damage, Chronic; Brain Diseases; Child; Glutam | 1971 |
8 trials available for phenytoin and Deficiency, Mental
| Article | Year |
|---|---|
Apparent increase in type I 5'-deiodinase activity induced by antiepileptic medication in mentally retarded subjects.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Hormones; Humans; Intellectual Disability; Iodide Per | 2002 |
Long-term use of phenytoin: effects on bone-marrow chromosomes in man.
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Chromosome Aberrations; | 1977 |
Oral use of chlorhexidine gluconate toothpaste in epileptic children.
Topics: Administration, Oral; Adolescent; Biguanides; Child; Child, Preschool; Chlorhexidine; Clinical Trial | 1978 |
The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study.
Topics: Adult; Dental Care for Disabled; Dental Plaque Index; Double-Blind Method; Epilepsy; Female; Folic A | 1991 |
Folate treatment of diphenylhydantoin-induced gingival hyperplasia.
Topics: Adolescent; Child; Epilepsy; Female; Folic Acid; Gingival Hyperplasia; Humans; Intellectual Disabili | 1989 |
Treatment of Dilantin gingival hyperplasia with Proxigel.
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Female; Gels; Gingival Hyperplasia; Gingivitis; Hu | 1974 |
Dilantin treatment of hospitalized cultural-familial retardates.
Topics: Adolescent; Aggression; Attention; Child; Child Behavior; Clinical Trials as Topic; Hospitalization; | 1970 |
Diphenylhydantoin as an anticonvulsant: evaluation of treatment in forty mentally subnormal epileptics.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Electroencephalography; Epilepsies, Par | 1969 |
97 other studies available for phenytoin and Deficiency, Mental
| Article | Year |
|---|---|
Valproate-Induced Pancytopenia and Phenytoin Toxicity in a Young Adult With Intellectual Disability and Mesial Temporal Lobe Sclerosis.
Topics: Humans; Intellectual Disability; Pancytopenia; Phenytoin; Sclerosis; Temporal Lobe; Valproic Acid; Y | 2021 |
[Early onset epileptic encephalopathy in a patient with mutation in
Topics: Age of Onset; Amino Acid Substitution; Anticonvulsants; Child, Preschool; Drug Resistant Epilepsy; D | 2017 |
Resolution of self-injury with phenytoin in a man with autism and intellectual disability: the role of frontal lobe seizures and catatonia.
Topics: Anticonvulsants; Autistic Disorder; Catatonia; Electroencephalography; Frontal Lobe; Humans; Impulsi | 2013 |
Independent predictors of delay in emergence from general anesthesia.
Topics: Adult; Ambulatory Care; Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthetic | 2015 |
[Resistance to vecuronium induced muscle relaxation in a patient with mental retardation receiving phenytoin for chronic anticonvulsant therapy].
Topics: Adult; Anesthesia, General; Drug Interactions; Drug Resistance; Epilepsy; Female; Humans; Intellectu | 2011 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, | 2011 |
Sturge Weber syndrome.
Topics: Adolescent; Anticonvulsants; Brain; Calcinosis; Child; Female; Humans; Intellectual Disability; Magn | 2011 |
BEHAVIOR DISORDERS OF INTEREST TO DERMATOLOGISTS.
Topics: Adolescent; Behavior; Bites and Stings; Child; Child Behavior Disorders; Dermatology; Epilepsy; Fing | 1963 |
CONVULSIONS.
Topics: Black People; Diagnosis, Differential; Epilepsy; Humans; Intellectual Disability; Phenobarbital; Phe | 1964 |
A STATE PROGRAM TO CONTROL PHENYLKETONURIA.
Topics: Adolescent; Blood; Child; Diet; Diet Therapy; Genetics, Medical; Humans; Infant; Intellectual Disabi | 1964 |
FINDINGS SUGGESTIVE OF SYSTEMIC LUPUS ERYTHEMATOSUS IN SUBJECTS ON CHRONIC ANTICONVULSANT THERAPY.
Topics: Anticonvulsants; Barbiturates; Drug Therapy; Intellectual Disability; Lupus Erythematosus, Systemic; | 1965 |
SYNDROME OF GINGIVAL HYPERPLASIA, HIRSUTISM, AND CONVULSIONS; DILANTIN INTOXICATION WITHOUT DILANTIN.
Topics: Ataxia; Brain Diseases; Child; Chlorpheniramine; Diagnosis, Differential; Diencephalon; Drug Therapy | 1965 |
Total external ophthalmoplegia induced by phenytoin: a case report and review of literature.
Topics: Adult; Anticonvulsants; Humans; Intellectual Disability; Male; Ophthalmoplegia; Phenobarbital; Pheny | 2004 |
Congenital bilateral perisylvian syndrome with partial epilepsy. Case report with long-term follow-up.
Topics: Adolescent; Cerebral Cortex; Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; | 2005 |
Purple glove syndrome associated with intravenous phenytoin administration in a patient with severe mental and motor retardation.
Topics: Adolescent; Anticonvulsants; Comorbidity; Diazepam; Disabled Children; Extravasation of Diagnostic a | 2006 |
Delineation of the phenotype associated with 7q36.1q36.2 deletion: long QT syndrome, renal hypoplasia and mental retardation.
Topics: Adult; Anticonvulsants; Base Sequence; Child; Chromosome Deletion; Chromosomes, Human, Pair 7; DNA P | 2008 |
Psychoactive drug treatment in retarded populations.
Topics: Adolescent; Adult; Antipsychotic Agents; Behavior; Child; Dyskinesia, Drug-Induced; Humans; Intellec | 1982 |
The prevalence of thyroid dysfunction in mentally handicapped in-patients.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cross-Sectional Studies; Down Syndrome; Female; Hu | 1982 |
Systemic effects of oral use of chlorhexidine gel in multihandicapped epileptic children.
Topics: Adolescent; Adult; Child; Child, Preschool; Chlorhexidine; Dental Care for Disabled; Double-Blind Me | 1981 |
Phenytoin induced gingival overgrowth in institutionalized epileptics.
Topics: Adolescent; Adult; Aged; Epilepsy; Female; Gingival Hyperplasia; Gingivitis; Humans; Institutionaliz | 1984 |
Reduction of polypharmacy for epilepsy in an institution for the retarded.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Huma | 1983 |
Salivary phenytoin levels in institutionalized epileptics.
Topics: Adolescent; Adult; Aged; Chromatography, Gas; Epilepsy; Humans; Institutionalization; Intellectual D | 1983 |
Effect of anticonvulsants on plasma haloperidol and thioridazine levels.
Topics: Adult; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Haloperidol; Humans; Intellectual | 1980 |
Dental root abnormalities and gingival overgrowth in epileptic patients receiving anticonvulsant therapy.
Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Humans; Intellectual Disability; M | 1980 |
Phenytoin-induced gingival overgrowth control in severely retarded children.
Topics: Adolescent; Child; Child, Preschool; Dental Plaque; Gingiva; Gingival Hyperplasia; Humans; Intellect | 1982 |
Effects of phenytoin withdrawal on matching to sample and workshop performance of mentally retarded individuals--a brief report.
Topics: Adolescent; Adult; Discrimination, Psychological; Female; Humans; Intellectual Disability; Male; Phe | 1982 |
Environmental antecedents which affect management and maintenance of programs for self-injurious behavior.
Topics: Adolescent; Adult; Behavior Therapy; Child; Day Care, Medical; Ecology; Female; Follow-Up Studies; H | 1982 |
The effects of phenytoin on rat development: an animal model system for fetal hydantoin syndrome.
Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Female; Growth Disorders; Humans; Inte | 1981 |
[The fetal hydantoin syndrome (author's transl)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Facial Expression; Female; Growth Disorders; H | 1981 |
Effects of phenytoin withdrawal on matching to sample and workshop performance of mentally retarded persons.
Topics: Adolescent; Adult; Color Perception; Discrimination Learning; Epilepsy; Female; Humans; Intellectual | 1981 |
Comparison of community and institutional prescription of antiepileptic drugs for individuals with learning disabilities.
Topics: Adult; Ambulatory Care; Anticonvulsants; Cognition Disorders; Day Care, Medical; Drug Therapy, Combi | 1994 |
[Rasmussen syndrome].
Topics: Acyclovir; Carbamazepine; Child, Preschool; Electroencephalography; Encephalitis; Epilepsies, Partia | 1993 |
The potential use of CO2-laser gingivectomy for phenytoin-induced gingival hyperplasia in mentally retarded patients.
Topics: Adolescent; Adult; Female; Gingival Hyperplasia; Gingivectomy; Humans; Intellectual Disability; Lase | 1993 |
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromoso | 1996 |
Polydactyly and fetal hydantoin syndrome: an additional component of the syndrome?
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child, Preschool; Craniofacial Abnormalities; | 1997 |
[A case of inv dup (15) mosaic with mental retardation and symptomatic generalized epilepsy].
Topics: Adult; Anticonvulsants; Chromosomes, Human, Pair 15; Epilepsy, Generalized; Female; Humans; Intellec | 1999 |
The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement.
Topics: Adolescent; Adult; Aged; Alleles; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 C | 2001 |
Effects of diphenylhydantoin in 41 epileptics institutionalized since childhood.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anemia; Central Nervous System Diseases; Child; Epilepsy; F | 1977 |
The management of drug induced gingival hyperplasia in mentally retarded patients with hemophilia: a report of two cases.
Topics: Adult; Child; Gingival Hemorrhage; Gingival Hyperplasia; Hemophilia A; Humans; Intellectual Disabili | 1978 |
Chronic diphenyl hydantoin encephalopathy in mentally retarded children and adolescent with severe epilepsy.
Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Chronic Disease; Epilepsy; Female; Human | 1979 |
Problems in counseling the epileptic mother.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Barbiturates; Epilepsy; Female; Genetic Counseling; | 1979 |
Problems with the use of conventional anticonvulsant drugs in mentally retarded individuals.
Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Cognition; Epilepsy; Humans; Intellec | 1979 |
Electroencephalography and phenytoin toxicity in mentally retarded epileptic patients.
Topics: Adolescent; Adult; Brain; Child; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; | 1978 |
[Do antiepileptics have a teratogenic effect?].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Congenital Abnormalities; Epilepsy; Female; Humans; In | 1978 |
Hypocalcaemia and secondary hyperparathyroidism in institutionalised mentally-retarded patients receiving anticonvulsant drugs: a survey of 292 patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; Hydroxycholecalci | 1978 |
Plasma 1,25-dihydroxyvitamin D levels in patients receiving anticonvulsant drugs.
Topics: Adult; Alkaline Phosphatase; Calcium; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; In | 1977 |
Cerebellar atrophy in phenytoin-treated mentally retarded epileptics.
Topics: Adolescent; Adult; Atrophy; Cerebellum; Child; Child, Preschool; Epilepsy; Female; Humans; Intellect | 1977 |
Skeletal status in mentally retarded patients on anticonvulsive therapy.
Topics: Absorptiometry, Photon; Adolescent; Adult; Anticonvulsants; Bone Development; Child; Female; Humans; | 1977 |
Phenytoin-induced dystonia and choreoathetosis in two retarded epileptic children.
Topics: Athetosis; Child; Chorea; Epilepsy; Humans; Intellectual Disability; Male; Muscular Diseases; Phenyt | 1976 |
[Psychotropic drugs for behavior disorder treatment in oligophrenic epileptics].
Topics: Adult; Epilepsy; Humans; Intellectual Disability; Methotrimeprazine; Phenytoin; Primidone; Promazine | 1976 |
Surgery of temporal lobe epilepsy.
Topics: Adolescent; Adult; Astrocytes; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Electroenc | 1975 |
Bone mineral in mentally retarded patients receiving long-term anticonvulsive therapy.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Body Weight; Bone and Bones; Child; Female; Humans; | 1975 |
Letter: Effects of medication of plasma vitamin A concentrations.
Topics: Humans; Intellectual Disability; Isosorbide Dinitrate; Phenobarbital; Phenytoin; Thioridazine; Vitam | 1976 |
[Pellagra in anticonvulsive therapy].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Intellect | 1990 |
[Oral findings in severely handicapped patients participating in the periodic dental check-up system for five years--dental caries, gingival recessions and hyperplasias, periodontal diseases].
Topics: Dental Care for Disabled; Dental Caries; DMF Index; Gingival Hyperplasia; Gingival Recession; Humans | 1990 |
A critical appraisal of recent drug research in mental retardation: the Coldwater studies.
Topics: Aggression; Antipsychotic Agents; Attitude of Health Personnel; Discrimination Learning; Humans; Ins | 1986 |
Anticonvulsant medication in a mental handicap hospital: 1972-1982.
Topics: Anticonvulsants; Carbamazepine; Female; Hospitals, Psychiatric; Humans; Intellectual Disability; Mal | 1987 |
Cholesterol--a factor in phenytoin-induced gingival enlargement?
Topics: Adolescent; Adult; Aged; Cholesterol; Female; Gingival Hyperplasia; Humans; Institutionalization; In | 1987 |
Folate metabolism and problem behaviour in mentally handicapped epileptics.
Topics: Adolescent; Adult; Aged; Epilepsy; Female; Folic Acid; Humans; Intellectual Disability; Male; Mental | 1987 |
Psychosis associated with anticonvulsant toxicity.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Humans; Intellectual Disability; Male; Phenytoin; | 1987 |
Prevalence of toxic anticonvulsant drug concentrations in mentally retarded persons with epilepsy.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Intellectual Disability; Kinetics; Male; Phenytoin; | 1986 |
Effect of influenza vaccine on serum anticonvulsant concentrations.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Influenza Vaccines; Inf | 1986 |
Disregulation of hypothalamic-pituitary-adrenal axis in the mentally retarded.
Topics: Adult; Depressive Disorder; Dexamethasone; Hospitalization; Humans; Hydrocortisone; Hypothalamo-Hypo | 1985 |
[Postnatal effects of intrauterine chemical stress].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Dyskinesia, Drug-Induced; Failure to Thrive; Female; Fet | 1985 |
Dermatologic disorders in institutionalized mental defectives.
Topics: Adenoma; Angiomatosis; Antipsychotic Agents; Cheilitis; Dermatitis, Seborrheic; Down Syndrome; Drug | 1971 |
Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.
Topics: Adult; Brain; Cerebellar Ataxia; Cerebral Ventriculography; Chlorpromazine; Diplopia; Electroconvuls | 1968 |
[Epilepsy and perinatal injury].
Topics: Adolescent; Adrenocorticotropic Hormone; Barbiturates; Birth Injuries; Brain Diseases; Cerebral Hemo | 1973 |
An aphasic syndrome in children.
Topics: Adolescent; Adrenocorticotropic Hormone; Aphasia; Biopsy; Brain; Child; Child Development; Child, Pr | 1974 |
Clinical experience with sulthiame (Ospolot).
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Epilepsy, Temporal Lobe; Female; Humans; | 1966 |
Emergency testing and routine monitoring of therapeutic drugs in a comprehensive analytical system.
Topics: Adolescent; Amobarbital; Chromatography, Gas; Chromatography, Thin Layer; Electroencephalography; Ep | 1974 |
Do anticonvulsants have a teratogenic effect?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital | 1974 |
Infratentorial gas encephalogram and mental retardation.
Topics: Abnormalities, Drug-Induced; Cerebellum; Female; Humans; Infant, Newborn; Intellectual Disability; M | 1972 |
Experiences with Bivotril in treatment of epilepsy--particularly minor motor epilepsy--in mentally retarded children.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Child; Child, Preschool; Chlor | 1973 |
Haptoglobin phenotype frequencies in mentally retarded persons.
Topics: Acid Phosphatase; Adenine Nucleotides; Adenosine; Alanine Transaminase; Aminohydrolases; Blood Prote | 1972 |
Effect of diphenylhydantoin therapy on folate metabolism of mentally retarded epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Azo Compounds; Child; Epilepsy; Female; FIGLU Test; Folic Acid; | 1973 |
Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy. I. A survey of 288 patients.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Child, Preschool; Female; Humans; | 1973 |
[Development inhibition in brain-damaged children due to anticonvulsants].
Topics: Anticonvulsants; Carbamazepine; Child; Child Development; Electroencephalography; Humans; Intellectu | 1973 |
Blood serotonin levels in severe mental retardation.
Topics: Age Factors; Blood Pressure; Child; Child, Preschool; Defecation; Diazepam; Diet; Female; Humans; Hy | 1973 |
Progressive encephalopathy due to chronic hydantoin intoxication.
Topics: Adolescent; Brain Diseases; Cerebellar Ataxia; Cerebellum; Child; Electroencephalography; Face; Fema | 1974 |
Oral bilateral symmetrical fibromas. Report of a case.
Topics: Adult; Ear Deformities, Acquired; Epilepsy, Tonic-Clonic; Fibroma; Humans; Hydantoins; Intellectual | 1966 |
Diphenylhydantoin as an anticonvulsant: protein binding and fluctuation of the serum and cerebrospinal fluid levels in forty mentally subnormal epileptics.
Topics: Epilepsy; Epilepsy, Tonic-Clonic; Humans; Intellectual Disability; Phenytoin; Protein Binding; Seizu | 1969 |
Drug interactions. 3. Therapeutic implications of enzyme induction.
Topics: Age Factors; Child; Child, Preschool; Drug Interactions; Drug Synergism; Enzyme Induction; Epilepsy; | 1972 |
[Megaloblastic anemia in children].
Topics: Adolescent; Anemia, Macrocytic; Blood Transfusion; Child; Female; Folic Acid; Humans; Intellectual D | 1971 |
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Human | 1971 |
Pseudodegenerative disease due to diphenylhydantoin intoxication.
Topics: Adolescent; Adult; Age Factors; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Hu | 1969 |
Central effects of diphenylhydantoin (dilantin) in epileptic oligophrenics during phenobarbital-primidone withdrawal, sodium bicarbonate, and ammonium chloride administration.
Topics: Adolescent; Adult; Ammonium Chloride; Bicarbonates; Epilepsy; Female; Humans; Hydrogen-Ion Concentra | 1969 |
Central effect of diphenylhydantoin (Dilantin) in epileptic oligophrenics during phenobarbital-primidone withdrawal, sodium bicarbonate, and ammonium chloride administration.
Topics: Adolescent; Adult; Ammonium Chloride; Bicarbonates; Epilepsy; Female; Humans; Hydrogen-Ion Concentra | 1969 |
Drug and environmental effects on DDT residues in human blood.
Topics: Adult; DDT; Environment; Female; Humans; Intellectual Disability; Male; Phenobarbital; Phenytoin; Ra | 1970 |
Ammonium chloride as an adjuvant to diphenyl-hydantoin therapy, and bulk ions in the CSF and serum in forty mentally subnormal epileptics.
Topics: Ammonium Chloride; Bicarbonates; Calcium; Carbon Dioxide; Chlorides; Epilepsy; Humans; Intellectual | 1970 |
[Therapy of epilepsy in mentally retarded children. Neuropsychiatric disorders caused by diphenylhydantoin].
Topics: Adolescent; Affective Symptoms; Ataxia; Child; Epilepsy; Humans; Intellectual Disability; Male; Musc | 1970 |
Effects of diphenylhydantoin, pH and total carbon dioxide in the cerebrospinal fluid during sodium bicarbonate and ammonium chloride intake in forty mentally sub-normal epileptics.
Topics: Acid-Base Equilibrium; Adolescent; Adult; Ammonium Chloride; Bicarbonates; Calcium; Carbon Dioxide; | 1970 |
Ammonium chloride as an adjuvant to diphenylhydantoin therapy, and pH, base bicarbonate and sodium in the serum of forty mentally subnormal epileptics.
Topics: Acid-Base Equilibrium; Ammonium Chloride; Bicarbonates; Chlorides; Epilepsy; Humans; Hydrogen-Ion Co | 1970 |
Low specific gravity syndrome.
Topics: Adult; Anticonvulsants; Calcium; Chlorides; Chronic Disease; Creatinine; Epilepsy; Female; Humans; I | 1968 |
Effect of phenytoin on the tryptophan load test.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Diagnosis, Differential; Epilepsy; Female; Humans; | 1968 |
Mental effects of anticonvulsants, and folic acid metabolism.
Topics: Age Factors; Anemia, Macrocytic; Anticonvulsants; Brain; Epilepsy; Female; Folic Acid; Folic Acid De | 1968 |
The effect of phenobarbital on diphenylhydantoin metabolism in children.
Topics: Child; Child, Preschool; Drug Synergism; Humans; Intellectual Disability; Phenobarbital; Phenytoin | 1969 |
Serial dilantin levels in mentally retarded children.
Topics: Child; Child, Preschool; Humans; Intellectual Disability; Phenytoin | 1969 |