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phenytoin and Deficiency, Folic Acid

phenytoin has been researched along with Deficiency, Folic Acid in 83 studies

Research Excerpts

ExcerptRelevanceReference
" Although phenytoin dosage remained relatively constant, plasma phenytoin concentrations during pregnancy were significantly lower than nonpregnant concentrations."5.26Hematologic effects of phenytoin therapy during pregnancy. ( Ramsay, RE; Strauss, RG; Wilder, BJ; Willmore, LJ, 1978)
" Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate."4.77Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985)
"During earlier investigations of the hepatic effects in dogs of long-term administration of phenytoin alone or in combination with primidone, erythrocytic macrocytosis, neutropenia, neutrophilic hypersegmentation, and thrombocytopenia were observed."3.68Hematologic values and plasma and tissue folate concentrations in dogs given phenytoin on a long-term basis. ( Bunch, SE; Cullen, JM; Easley, JR, 1990)
"In a survey of the red cell folate status of 200 patients with epilepsy, compared to 72 controls, we found that median red cell folate levels were reduced significantly in patients treated with phenytoin (p less than 0."3.67A comparative study of the relative effects of anticonvulsant drugs and dietary folate on the red cell folate status of patients with epilepsy. ( Baker, M; Bissessar, A; Callaghan, N; Crowley, M; Goggin, T; Gough, H, 1987)
" The treatment of status epilepticus with intravenous phenytoin is effective."3.66Epilepsy and pregnancy. ( Bruni, J; Willmore, LJ, 1979)
" Although one of the first associations between anticonvulsant therapy and an adverse development effect in humans was noted in 1964 (104), the mechanism(s) whereby these adverse effects occur has thus far eluded research efforts."2.38The embryotoxicity of phenytoin: an update on possible mechanisms. ( Hansen, DK, 1991)
" Although phenytoin dosage remained relatively constant, plasma phenytoin concentrations during pregnancy were significantly lower than nonpregnant concentrations."1.26Hematologic effects of phenytoin therapy during pregnancy. ( Ramsay, RE; Strauss, RG; Wilder, BJ; Willmore, LJ, 1978)
" This indicates that long-term use of phenytoin does not cause a clinically significant state of folate deficiency, unless some other contributing factors are present."1.26Long-term of phenytoin: Effects on whole blood and red cell folate and haematological parameters. ( Knuutila, S; Tammisto, P; Tontti, K; Weber, TH, 1977)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199078 (93.98)18.7374
1990's4 (4.82)18.2507
2000's1 (1.20)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PODESTA, LD1
DEVOTO, RA1
PRECERUTTI, AS1
HANSEN, HA1
NORDQVIST, P1
SOURANDER, P1
HAMFELT, A1
KILLANDER, A1
MALERS, E1
DEVERDIER, CH1
Dahlke, MB1
Mertens-Roesler, E1
Rivey, MP1
Schottelius, DD1
Berg, MJ1
Reynolds, EH12
Billings, RE1
Inoue, F1
Walsh, RJ1
Colman, N1
Hettiarachchy, N1
Herbert, V2
Mallek, HM1
Nakamoto, T1
Blair, JA1
Lucas, ML1
Swanston-Flatt, SK1
Drinka, PJ1
Langer, EH1
Voeks, SK1
Goodwin, JS1
Schwaninger, M1
Ringleb, P1
Winter, R1
Kohl, B1
Fiehn, W1
Rieser, PA1
Walter-Sack, I1
Blain, H1
Hamdan, KA1
Blain, A1
Jeandel, C1
Ziegler, DK1
Netzloff, ML1
Streiff, RR2
Frias, JL1
Rennert, OM1
Bruni, J1
Willmore, LJ2
Strauss, RG1
Ramsay, RE1
Wilder, BJ1
Weber, TH1
Knuutila, S1
Tammisto, P1
Tontti, K1
Trimble, MR3
Williams, DL1
Spray, GH2
Hansen, DK1
Bunch, SE1
Easley, JR1
Cullen, JM1
Shalev, O1
Gilon, D1
Nubani, NH1
Goggin, T1
Gough, H1
Bissessar, A1
Crowley, M1
Baker, M1
Callaghan, N1
Tucker, AN1
Hong, L1
Boorman, GA1
Luster, MI1
Corbett, JA1
Nichol, TC1
Pereira, A1
Cervantes, F1
Rozman, C1
Baylis, EM1
Crowley, JM1
Preece, JM1
Sylvester, PE1
Marks, V1
Korczyn, AD1
Elian, M1
Don, R1
Bornstein, B1
Hoffbrand, AV2
Necheles, TF1
Rosenberg, IH1
Godwin, HA1
Castle, WB1
Viukari, NM1
Fehling, C1
Jägerstad, M1
Lindstrand, K1
Westesson, AK1
Brubakk, O1
Elsborg, L2
Mercier-Parot, L1
Tuchmann-Duplessis, H1
Taguchi, H3
Gibberd, FB1
Robenberg, IH1
Stein, GM1
Lewis, H1
Arakawa, T2
Perrault, M1
Dry, J1
Hara, K1
Hasei, T1
Iwasaki, I1
Hiraki, K1
Loyning, Y1
Henriksen, O1
Narisawa, K1
Honda, Y1
Reizenstein, P1
Lund, L1
Magnus, E1
Bowe, JC1
Cornish, EJ1
Dawson, M1
Maxwell, JD1
Hunter, J1
Stewart, DA1
Ardeman, S1
Williams, R1
Richens, A1
Burns, DG1
Ellegaard, J1
Esmann, V1
Kariks, J1
Perry, SW1
Wood, D1
Preece, J1
Johnson, AL1
Chanarin, I2
Milner, G1
Matthews, DM2
Allen, CD2
Bernstein, LH1
Gutstein, S1
Weiner, SV1
Boykin, ME1
Hooshmand, H1
Klipstein, FA1
Doe, WF1
Reed, PI1
Scott, JM1
Pritchard, JA1
Scott, DE1
Whalley, PJ1
Andreasen, PB1
Hansen, JM1
Skovsted, L1
Siersbaek-Nielsen, K1
Miller, DR1
Rothman, D1
Ward, A1
Perry, J1
Gordon, N1
Tisman, G1
Jensen, ON1
Olesen, OV1
Osuntokun, BO1
Hallpike, JF1
Phillips, BM1

Reviews

8 reviews available for phenytoin and Deficiency, Folic Acid

ArticleYear
Phenytoin-folic acid: a review.
    Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:4

    Topics: Folic Acid; Folic Acid Deficiency; Humans; Nervous System Diseases; Phenytoin; Tissue Distribution

1984
Mental effects of antiepileptic medication: a review.
    Epilepsia, 1983, Volume: 24 Suppl 2

    Topics: Adolescent; Adult; Anticonvulsants; Attention; Barbiturates; Brain Chemistry; Carbamazepine; Child;

1983
Toxicity to the nervous system of diphenylhydantoin: a review.
    International journal of neurology, 1978, Volume: 11, Issue:4

    Topics: Adrenal Cortex Hormones; Animals; Cardiovascular Diseases; Cerebellar Ataxia; Cerebellar Diseases; C

1978
The embryotoxicity of phenytoin: an update on possible mechanisms.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 197, Issue:4

    Topics: Animals; Biotransformation; Folic Acid Deficiency; Glucocorticoids; Humans; Phenytoin; Teratogens

1991
Adverse neuropsychiatric effects of anticonvulsant drugs.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba

1985
[Disorders of folate metabolism--primary and secondary metabolic disorders].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1972, Volume: 17, Issue:3

    Topics: Animals; Child; DNA; Folic Acid; Folic Acid Deficiency; Formamides; Histidine; Humans; Liver; Metabo

1972
The five possible causes of all nutrient deficiency: illustrated by deficiencies of vitamin B 12 and folic acid.
    Australian and New Zealand journal of medicine, 1972, Volume: 2, Issue:1

    Topics: Bile; Biological Transport, Active; Enzymes; Folic Acid; Folic Acid Deficiency; Food Deprivation; Ga

1972
Cerebrospinal folate levels in epileptics and their response to folate therapy.
    Nutrition reviews, 1974, Volume: 32, Issue:3

    Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Def

1974

Trials

5 trials available for phenytoin and Deficiency, Folic Acid

ArticleYear
Influence of folic acid on blood-phenytoin levels.
    Lancet (London, England), 1971, Jan-09, Volume: 1, Issue:7689

    Topics: Adult; Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenobarbital; Ph

1971
Impairment of intestinal deconjugation of dietary folate. A possible explanation of megaloblastic anaemia associated with phenytoin therapy.
    Lancet (London, England), 1968, Sep-07, Volume: 2, Issue:7567

    Topics: Anemia, Macrocytic; Biological Assay; Folic Acid; Folic Acid Deficiency; Gastrointestinal Hormones;

1968
Cerebrospinal folate levels in epileptics and their response to folate therapy.
    Nutrition reviews, 1974, Volume: 32, Issue:3

    Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Def

1974
Evaluation of folic acid supplements in children taking phenytoin.
    Developmental medicine and child neurology, 1971, Volume: 13, Issue:3

    Topics: Adolescent; Child; Child Behavior Disorders; Clinical Trials as Topic; Electroencephalography; Epile

1971
Folate status and requirement in pregnancy.
    British medical journal, 1968, May-18, Volume: 2, Issue:5602

    Topics: Abortion, Spontaneous; Anemia, Macrocytic; Birth Weight; Diet; Female; Folic Acid; Folic Acid Defici

1968

Other Studies

71 other studies available for phenytoin and Deficiency, Folic Acid

ArticleYear
[MEGALOBLASTIC ANEMIA PRODUCED BY ANTICONVULSANTS].
    Prensa medica argentina, 1963, Oct-25, Volume: 50

    Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Argentina; Barbiturates; Blood C

1963
MEGALOBLASTIC ANEMIA AND NEUROLOGIC DISTURBANCES COMBINED WITH FOLIC ACID DEFICIENCY. OBSERVATIONS ON AN EPILEPTIC PATIENT TREATED WITH ANTICONVULSANTS.
    Acta medica Scandinavica, 1964, Volume: 176

    Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Avitaminosis; Barbiturates; Brai

1964
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT DRUGS: STUDIES ON A CASE WITH FOUR RELAPSES.
    Acta medica Scandinavica, 1965, Volume: 177

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Drug Therapy; Electrophoresis; Epilepsy;

1965
Malabsorption of folic acid due to diphenylhydantoin.
    Blood, 1967, Volume: 30, Issue:3

    Topics: Anemia, Macrocytic; Animals; Body Fluids; Child; Erythrocytes; Folic Acid; Folic Acid Deficiency; Hu

1967
Interactions between folate metabolism, phenytoin metabolism, and liver microsomal cytochrome P450.
    Drug-nutrient interactions, 1984, Volume: 3, Issue:1

    Topics: Animals; Diet; Folic Acid; Folic Acid Deficiency; In Vitro Techniques; Liver; Male; Microsomes, Live

1984
Folate supplements and phenytoin-salicylate interaction.
    Neurology, 1983, Volume: 33, Issue:1

    Topics: Adult; Aspirin; Drug Interactions; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenytoin; Seizu

1983
Detection of a milk factor that facilitates folate uptake by intestinal cells.
    Science (New York, N.Y.), 1981, Mar-27, Volume: 211, Issue:4489

    Topics: Animals; Calcium; Carrier Proteins; Cattle; Edetic Acid; Female; Folate Receptors, GPI-Anchored; Fol

1981
Anticonvulsants and mental symptoms.
    Acta neurologica Scandinavica. Supplementum, 1980, Volume: 80

    Topics: Anticonvulsants; Barbiturates; Biogenic Amines; Epilepsy; Folic Acid Deficiency; Hormones; Humans; M

1980
Dilantin and folic acid status. Clinical implications for the periodontist.
    Journal of periodontology, 1981, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Anemia, Megaloblastic; Child; Female; Folic Acid; Folic Acid Deficiency; Gingival

1981
Intestinal folic acid absorption and the acid microclimate. The effects of compounds relevant to folate malabsorption.
    Pflugers Archiv : European journal of physiology, 1981, Volume: 392, Issue:1

    Topics: Animals; Ethanol; Folic Acid; Folic Acid Deficiency; Hydrogen-Ion Concentration; In Vitro Techniques

1981
Low serum folic acid levels in a nursing home population: a clinical experience.
    Journal of the American College of Nutrition, 1993, Volume: 12, Issue:2

    Topics: Aged; Aged, 80 and over; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Hemoglobins

1993
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
    Epilepsia, 1999, Volume: 40, Issue:3

    Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epi

1999
Aplastic anemia induced by phenytoin: a geriatric case with severe folic acid deficiency.
    Journal of the American Geriatrics Society, 2002, Volume: 50, Issue:2

    Topics: Aged; Anemia, Aplastic; Anticonvulsants; Folic Acid Deficiency; Humans; Male; Phenytoin; Pneumonia

2002
Folate antagonism following teratogenic exposure to diphenylhydantoin.
    Teratology, 1979, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Resorption; Fetus; Folic Acid Antagonists; Folic

1979
Epilepsy and pregnancy.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1979, Volume: 6, Issue:3

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Blood Coagulation Disorders; Chromosome Aberrations; C

1979
Hematologic effects of phenytoin therapy during pregnancy.
    Obstetrics and gynecology, 1978, Volume: 51, Issue:6

    Topics: Carotenoids; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Hematologic Tests; Humans; Phenyto

1978
Long-term of phenytoin: Effects on whole blood and red cell folate and haematological parameters.
    Scandinavian journal of haematology, 1977, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Anemia, Megaloblastic; Child; Child, Preschool; Epilepsy; Erythrocyte Count; Eryt

1977
Anticonvulsant drugs and mental symptoms: a review.
    Psychological medicine, 1976, Volume: 6, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Folic Acid

1976
Effect of some anticonvulsant drugs on depletion of folate in rats on a vitamin B12-deficient diet.
    British journal of haematology, 1976, Volume: 33, Issue:2

    Topics: Animals; Dietary Proteins; Female; Folic Acid Deficiency; Formiminoglutamic Acid; Liver; Phenobarbit

1976
Hematologic values and plasma and tissue folate concentrations in dogs given phenytoin on a long-term basis.
    American journal of veterinary research, 1990, Volume: 51, Issue:11

    Topics: Animals; Blood Cell Count; Dog Diseases; Dogs; Erythrocytes; Female; Folic Acid; Folic Acid Deficien

1990
Masked phenytoin-induced megaloblastic anemia in beta-thalassemia minor.
    Acta haematologica, 1987, Volume: 77, Issue:3

    Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Folic Acid Deficiency; Humans; Phenytoin;

1987
A comparative study of the relative effects of anticonvulsant drugs and dietary folate on the red cell folate status of patients with epilepsy.
    The Quarterly journal of medicine, 1987, Volume: 65, Issue:247

    Topics: Adult; Anticonvulsants; Carbamazepine; Diet; Drug Therapy, Combination; Epilepsy; Erythrocytes; Fema

1987
Alterations in bone marrow cell cycle kinetics by diphenylhydantoin and folate deficiency are restored by thymic peptides.
    Thymus, 1986, Volume: 8, Issue:3

    Topics: Animals; Cell Cycle; Colony-Forming Units Assay; Female; Folic Acid Deficiency; Hematopoietic Stem C

1986
Behavioral and cognitive impairments in children with epilepsy: the long-term effects of anticonvulsant therapy.
    Journal of the American Academy of Child Psychiatry, 1985, Volume: 24, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child Behavior Disorders; Child, Preschool; Electroencephalograp

1985
[Macrocytic anemia due to folic acid deficiency and non-Hodgkin's lymphoma associated with prolonged diphenylhydantoin ingestion].
    Medicina clinica, 1985, Oct-19, Volume: 85, Issue:12

    Topics: Aged; Anemia, Macrocytic; Epilepsy; Female; Folic Acid Deficiency; Humans; Lymphoma; Phenytoin; Time

1985
Phenytoin and folate deficiency: failure to show dose dependency.
    Journal of neurology, 1974, Jun-27, Volume: 207, Issue:2

    Topics: Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenytoin; Time Factors

1974
Effects of folic acid on the mental state and fit-frequency of drug-treated epileptic patients.
    Lancet (London, England), 1967, May-20, Volume: 1, Issue:7499

    Topics: Adolescent; Adult; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Humans; M

1967
Mechanism of folate deficiency in patients receiving phenytoin.
    Lancet (London, England), 1968, Sep-07, Volume: 2, Issue:7567

    Topics: Aged; Biological Assay; Dietary Proteins; Female; Folic Acid; Folic Acid Deficiency; Gastrointestina

1968
Phenytoin, folates, and A.T.P.ase.
    Lancet (London, England), 1970, May-09, Volume: 1, Issue:7654

    Topics: Adenosine Triphosphatases; Folic Acid; Folic Acid Deficiency; Humans; Phenytoin

1970
The effect of anticonvulsant therapy upon the absorption of folates.
    Clinical science, 1973, Volume: 44, Issue:6

    Topics: Adult; Aged; Anticonvulsants; Biological Assay; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans;

1973
[Phenytoin-induced folic acid deficiency].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Jun-30, Volume: 93, Issue:18

    Topics: Adult; Aged; Anemia, Macrocytic; Epilepsy; Epilepsy, Post-Traumatic; Female; Folic Acid; Folic Acid

1973
Inhibition of intestinal absorption of folic acid by phenytoin.
    Acta haematologica, 1974, Volume: 52, Issue:1

    Topics: Adult; Aged; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Hydrogen-Ion Concentration

1974
The dysmorphogenic potential of phenytoin: experimental observations.
    Drugs, 1974, Volume: 8, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Epilepsy; Female; Fetus; Folic Acid; Folic Acid Deficiency; Ha

1974
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. I. Clinical and nutritional study on megalobastic anemia due to anticonvulsants.
    Acta medicinae Okayama, 1971, Volume: 25, Issue:5

    Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Diet; Epilepsy, Temporal Lobe; Folic Acid; Folic Acid De

1971
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. 2. Investigations on patients receiving anticonvulsants and experimental study on the effect of diphenylhydantoin on the absorption of folic acid in rats.
    Acta medicinae Okayama, 1971, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Animals; Anticonvulsants; Cell Nucleus; Depression, Chemical; Epithelial Cells; F

1971
Iatrogenic disorders in epilepsy.
    Modern trends in neurology, 1970, Volume: 5, Issue:0

    Topics: Adrenal Insufficiency; Anemia, Macrocytic; Animals; Anticonvulsants; Cats; Cerebellar Diseases; Drug

1970
Epilepsy.
    British medical journal, 1969, Nov-01, Volume: 4, Issue:5678

    Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, T

1969
Drugs and folic acid absorption.
    Gastroenterology, 1972, Volume: 63, Issue:2

    Topics: Animals; Contraceptives, Oral; Folic Acid; Folic Acid Deficiency; Intestinal Absorption; Methotrexat

1972
Iatrogenic nutritional effects of anticonvulsants.
    The Proceedings of the Nutrition Society, 1974, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Blood Coagulation Disorders; Bone Diseases; Child; Child, Presch

1974
Oral changes in a folic acid deficient patient precipitated by anticonvulsant drug therapy.
    Journal of periodontology, 1973, Volume: 44, Issue:10

    Topics: Adolescent; Female; Folic Acid Deficiency; Gingival Hyperplasia; Humans; Oral Manifestations; Phenyt

1973
[Hydantoins today].
    La Revue du praticien, 1972, Dec-21, Volume: 22, Issue:33

    Topics: Arrhythmias, Cardiac; Carbohydrate Metabolism; Central Nervous System; Diabetic Neuropathies; Epilep

1972
Clinical conference: megaloblastic anemia associated with anticonvulsant drugs.
    Journal of the Tennessee Medical Association, 1972, Volume: 65, Issue:9

    Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Female; Folic Acid; Folic Acid Deficiency; Humans; Pheno

1972
[Nutritional and experimental studies on folic acid deficiency due to anticonvulsants].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1972, Volume: 61, Issue:7

    Topics: Adult; Anemia, Macrocytic; Animals; Anticonvulsants; Diet; Epilepsy; Folic Acid; Folic Acid Deficien

1972
[Editorial: Antiepileptic agents--folic acid].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Jun-30, Volume: 93, Issue:18

    Topics: Anemia, Macrocytic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; P

1973
Effect of diphenylhydantoin administration on single carbon metabolism in folate deficient rats.
    The Tohoku journal of experimental medicine, 1973, Volume: 110, Issue:4

    Topics: Acrylates; Animals; Azo Compounds; Carbon; Carbon Dioxide; Carbon Radioisotopes; Folic Acid Deficien

1973
Effect of anticonvulsive drugs on folate absorption and the cerebrospinal folate pump.
    Scandinavian journal of haematology, 1973, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Carbamazepine; Depression, Chemical; Epilepsy; Female; Folic Acid; Folic Ac

1973
[Folic acid and folate values in plasma and whole blood].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: Acute Disease; Barbiturates; Contraceptives, Oral; Epilepsy; Ethanol; Female; Folic Acid; Folic Acid

1973
Folate metabolism and anticonvulsant therapy.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:1

    Topics: Anticonvulsants; Blood-Brain Barrier; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primi

1974
Folate deficiency after anticonvulsant drugs: an effect of hepatic enzyme induction?
    British medical journal, 1972, Jan-29, Volume: 1, Issue:5795

    Topics: Adipates; Adolescent; Anticonvulsants; Child; Enzyme Induction; Epilepsy; Female; Folic Acid; Folic

1972
Enzyme induction and folate deficiency.
    British medical journal, 1972, Feb-26, Volume: 1, Issue:5799

    Topics: Anticonvulsants; Enzyme Induction; Folic Acid Deficiency; Humans; Liver; Phenytoin

1972
Folate deficiency and anticonvulsant drugs.
    British medical journal, 1972, Apr-15, Volume: 2, Issue:5806

    Topics: Animals; Enzyme Induction; Female; Folic Acid; Folic Acid Deficiency; Liver; Male; Oxidoreductases;

1972
Folate deficiency in malnutrition, malabsorption, and during phenytoin treatment diagnosed by determination of serine synthesis in lymphocytes.
    European journal of clinical investigation, 1972, Volume: 2, Issue:5

    Topics: Adult; Aged; Anemia; Carbon Isotopes; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficie

1972
Serum folic acid and phenytoin levels in permanently hospitalized epileptic patients receiving anticonvulsant drug therapy.
    The Medical journal of Australia, 1971, Aug-14, Volume: 2, Issue:7

    Topics: Central Nervous System Diseases; Epilepsy; Folic Acid; Folic Acid Deficiency; Hospitalization; Human

1971
Drugs and folic acid utilization.
    Nutrition reviews, 1971, Volume: 29, Issue:2

    Topics: Anemia, Macrocytic; Contraceptives, Oral; Female; Folic Acid; Folic Acid Deficiency; Glutamates; Hum

1971
Folate metabolism in epileptic and psychiatric patients.
    Journal of neurology, neurosurgery, and psychiatry, 1971, Volume: 34, Issue:6

    Topics: Adult; Antidepressive Agents; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Hum

1971
Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms.
    Epilepsia, 1966, Volume: 7, Issue:4

    Topics: Adult; Anemia, Macrocytic; Female; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Age

1966
Folate and vitamin B12 in epilepsy.
    British medical journal, 1970, Sep-05, Volume: 3, Issue:5722

    Topics: Animals; Brain Chemistry; Cats; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenytoin; Rats

1970
Gamma glutamyl carboxypeptidase (conjugase), the folic acid-releasing enzyme of intestinal mucosa.
    The American journal of clinical nutrition, 1970, Volume: 23, Issue:7

    Topics: Animals; Bile Acids and Salts; Buffers; Carboxypeptidases; Celiac Disease; Folic Acid; Folic Acid De

1970
CSF and serum folic acid and protein changes with diphenylhydantoin treatment: laboratory and clinical correlations.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Aged; Blood Proteins; Cerebrospinal Fluid Proteins; Electroencephalography; Folic Acid; Folic Acid D

1970
Brain folate concentration in folate-deficient rats receiving diphenylhydantoin.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Erythrocytes; Folic Acid; Folic Acid Deficiency; Intestinal Mucosa;

1970
Jejunal pH and folic acid.
    British medical journal, 1971, Mar-20, Volume: 1, Issue:5750

    Topics: Folic Acid Deficiency; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Jejunum; Phenytoin

1971
Maternal folate deficiency and pregnancy wastage. IV. Effects of folic acid supplements, anticonvulsants, and oral contraceptives.
    American journal of obstetrics and gynecology, 1971, Feb-01, Volume: 109, Issue:3

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anemia, Macrocytic; Anemia, Sickle Cell; Anemia,

1971
Folic acid and the half-life of diphenylhydantoin in man.
    Acta neurologica Scandinavica, 1971, Volume: 47, Issue:1

    Topics: Carbon Isotopes; Female; Folic Acid; Folic Acid Deficiency; Half-Life; Humans; Kidney Diseases; Live

1971
Serum folate deficiency in children receiving anticonvulsant therapy.
    Pediatrics, 1968, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Epilepsy; Erythrocyte Coun

1968
Folic acid deficiency from anticonvulsant therapy.
    Developmental medicine and child neurology, 1968, Volume: 10, Issue:4

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Defic

1968
Gastrointestinal dysfunction in anticonvulsant megaloblastic anaemia.
    Danish medical bulletin, 1968, Volume: 15, Issue:6

    Topics: Adult; Anemia, Macrocytic; Female; Folic Acid Deficiency; Gastrointestinal Diseases; Humans; Phenyto

1968
Mental effects of anticonvulsants, and folic acid metabolism.
    Brain : a journal of neurology, 1968, Volume: 91, Issue:2

    Topics: Age Factors; Anemia, Macrocytic; Anticonvulsants; Brain; Epilepsy; Female; Folic Acid; Folic Acid De

1968
Dilantin and folic acid deficiency.
    Annals of internal medicine, 1969, Volume: 70, Issue:1

    Topics: Anemia, Macrocytic; Folic Acid Deficiency; Humans; Phenytoin

1969
Folic acid and anticonvulsive drugs.
    Archives of neurology, 1969, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Erythrocyte Count; Female; FIGLU Test; Folic Acid; Fol

1969
Anticonvulsant therapy, folic acid deficiency, and neuropsychiatric disorders.
    British medical journal, 1969, Jun-07, Volume: 2, Issue:5657

    Topics: Adolescent; Avitaminosis; Female; Folic Acid Deficiency; Humans; Nervous System Diseases; Phenytoin

1969
Reversible absorptive defects in anticonvulsant megaloblastic anaemia.
    Journal of clinical pathology, 1965, Volume: 18, Issue:5

    Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Blood; Female; FIGLU Test; Folic Acid Deficiency; Humans

1965