Page last updated: 2024-10-21

phenytoin and DRESS Syndrome

phenytoin has been researched along with DRESS Syndrome in 17 studies

Research Excerpts

ExcerptRelevanceReference
"A total of 141 drug-event combinations were reported and results of disproportionality analysis indicate the positive signal of DRESS syndrome with clobazam."8.12Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis. ( Kumar, A; Sharma, A, 2022)
" Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a very serious but rare adverse effect of anticonvulsants such as carbamazepine and phenytoin; however, the reported incidence on zonisamide is scant."8.12Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. ( Govindan, R; Sharma, S; Trivedi, A, 2022)
"Phenytoin (PHE) and carbamazepine (CBZ) are first rank causative drugs that can induce drug rash with eosinophilia and systemic symptoms (DRESS) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)."7.88Evaluation of a lymphocyte transformation test and cytokine detection assay to identify phenytoin and carbamazepine provoked DRESS or SJS/TEN in epilepsy patients. ( Kumkamthornkul, P; Srinoulprasert, Y; Tansit, T; Tuchinda, P; Udnaen, S, 2018)
"DRESS syndrome is a hypersensitivity reaction that takes weeks to manifest, and is characterized by rash, leukocytosis with eosinophilia, adenopathies, liver involvement, and reactivation of the herpes virus 6, being more frequent in carbamazepine or phenytoin, and in rare cases to oxcarbazepine."5.05Anticonvulsant hypersensitivity syndrome: clinic case and literature review. ( Fraire, JA; Leonangeli, S; Loza, JL, 2020)
"A total of 141 drug-event combinations were reported and results of disproportionality analysis indicate the positive signal of DRESS syndrome with clobazam."4.12Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis. ( Kumar, A; Sharma, A, 2022)
" Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a very serious but rare adverse effect of anticonvulsants such as carbamazepine and phenytoin; however, the reported incidence on zonisamide is scant."4.12Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. ( Govindan, R; Sharma, S; Trivedi, A, 2022)
"Phenytoin (PHE) and carbamazepine (CBZ) are first rank causative drugs that can induce drug rash with eosinophilia and systemic symptoms (DRESS) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)."3.88Evaluation of a lymphocyte transformation test and cytokine detection assay to identify phenytoin and carbamazepine provoked DRESS or SJS/TEN in epilepsy patients. ( Kumkamthornkul, P; Srinoulprasert, Y; Tansit, T; Tuchinda, P; Udnaen, S, 2018)
"Phenytoin (PHT) is a common cause of severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and drug reaction with eosinophilia and systemic symptoms (DRESS)."3.85Association of HLA-B*15:13 and HLA-B*15:02 with phenytoin-induced severe cutaneous adverse reactions in a Malay population. ( Chang, CC; Choon, SE; Chung, WH; Hussein, SH; Lee, CK; Lim, KS; Murad, S; Ng, CC; Too, CL, 2017)
"Phenytoin (PHT) is a common causative drug for severe cutaneous adverse drug reactions (SCARs) in children."1.56Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children. ( Benjaponpitak, S; Inunchot, W; Kamchaisatian, W; Khongkhatithuml, C; Likkasittipan, P; Mahasirimongkol, S; Manuyakorn, W; Suvichapanich, S; Thampratankul, L; Wattanapokayakit, S; Wichukchinda, N, 2020)
"Phenytoin drug reaction with eosinophilia and systemic symptoms (DRESS) in 3 Aboriginal Australians positive for HLA-B*56:02 has been previously reported."1.51High and variable population prevalence of HLA-B*56:02 in indigenous Australians and relation to phenytoin-associated drug reaction with eosinophilia and systemic symptoms. ( Barratt, DT; Gabb, GM; Ilyas, F; Moore, K; Phillips, EJ; Somogyi, AA, 2019)
"DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs."1.42[DRESS syndrome: Report of nine cases]. ( Barbosa-Moreno, LE; Guerrero-González, GA; Martínez-Villarreal, JD; Ocampo-Candiani, J; Ocampo-Garza, J; Ocampo-Garza, SS, 2015)
"A middle-aged man diagnosed with a drug reaction with eosinophilia and systemic symptom (DRESS) syndrome, secondary to phenytoin use, subsequently developed thrombotic thrombocytopaenic purpura."1.38DRESS syndrome and thrombotic thrombocytopaenic purpura: are they related? ( Alirhayim, Z; Hassan, S; Khoulani, D; Sandouk, Z, 2012)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (70.59)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Sharma, A1
Kumar, A1
Manuyakorn, W1
Likkasittipan, P1
Wattanapokayakit, S1
Suvichapanich, S1
Inunchot, W1
Wichukchinda, N1
Khongkhatithuml, C1
Thampratankul, L1
Kamchaisatian, W1
Benjaponpitak, S1
Mahasirimongkol, S1
Leonangeli, S1
Fraire, JA1
Loza, JL1
Trivedi, A1
Sharma, S1
Govindan, R1
Chung, SJ1
Ahn, KM1
Oh, JH1
Shim, JS1
Park, HW1
Riaz, M1
Ragsdale, BD1
Rahman, ZU1
Nigam, G1
Behera, SK1
Das, S1
Xavier, AS1
Selvarajan, S1
Kumkamthornkul, P1
Udnaen, S1
Tansit, T1
Tuchinda, P1
Srinoulprasert, Y1
Somogyi, AA1
Barratt, DT1
Phillips, EJ1
Moore, K1
Ilyas, F1
Gabb, GM1
Velasco, MJ1
McDermott, J1
Ocampo-Garza, J1
Ocampo-Garza, SS1
Martínez-Villarreal, JD1
Barbosa-Moreno, LE1
Guerrero-González, GA1
Ocampo-Candiani, J1
Gleeson, TP1
Griswold, MK1
Broach, J1
Babu, KM1
Chang, CC1
Ng, CC1
Too, CL1
Choon, SE1
Lee, CK1
Chung, WH1
Hussein, SH1
Lim, KS1
Murad, S1
Deka, NM1
Dass, R1
Das, BK1
Hoque, R1
Gupta, A1
Srivastava, VK1
Rizvi, I1
Aziz, A1
Morita, M1
Komine, M1
Takatsuka, Y1
Hosoda, S1
Onda, H1
Maekawa, T1
Murata, S1
Ohtsuki, M1
Sandouk, Z1
Alirhayim, Z1
Khoulani, D1
Hassan, S1

Reviews

2 reviews available for phenytoin and DRESS Syndrome

ArticleYear
Anticonvulsant hypersensitivity syndrome: clinic case and literature review.
    Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina), 2020, 08-21, Volume: 77, Issue:3

    Topics: Adult; Anticonvulsants; Argentina; Carbamazepine; Drug Hypersensitivity Syndrome; Female; Humans; Ph

2020
DRESS syndrome: a detailed insight.
    Hospital practice (1995), 2018, Volume: 46, Issue:3

    Topics: Adrenal Cortex Hormones; Anticonvulsants; Diagnosis, Differential; Drug Hypersensitivity Syndrome; E

2018

Other Studies

15 other studies available for phenytoin and DRESS Syndrome

ArticleYear
Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis.
    Acta neurologica Scandinavica, 2022, Volume: 146, Issue:5

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Clobazam; Drug Hypersensitivity Syndrome; Eosinophilia; Fema

2022
Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children.
    Epilepsy research, 2020, Volume: 162

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Hypersensitivity Syndrome; Female; Geneti

2020
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide.
    European journal of hospital pharmacy : science and practice, 2022, Volume: 29, Issue:4

    Topics: Child; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Humans; Male; Phenytoin; Zonisamide

2022
Incidence rates of severe cutaneous adverse reactions due to antiseizure medication: A nationwide study using health claims data in Korea.
    Epilepsia, 2021, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Drug Hypersensiti

2021
Drug rash with eosinophilia and systemic symptoms (DRESS) caused by phenytoin.
    BMJ case reports, 2017, Aug-22, Volume: 2017

    Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Diagnosis, Differential; Drug Hypersensitivity Syn

2017
Evaluation of a lymphocyte transformation test and cytokine detection assay to identify phenytoin and carbamazepine provoked DRESS or SJS/TEN in epilepsy patients.
    International immunopharmacology, 2018, Volume: 63

    Topics: Adult; Anticonvulsants; Carbamazepine; Cytokines; Drug Hypersensitivity Syndrome; Epilepsy; Female;

2018
High and variable population prevalence of HLA-B*56:02 in indigenous Australians and relation to phenytoin-associated drug reaction with eosinophilia and systemic symptoms.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:9

    Topics: Adolescent; Adult; Aged; Australia; Biological Variation, Population; Cohort Studies; Cytochrome P-4

2019
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome and hepatitis induced by phenytoin.
    International journal of dermatology, 2014, Volume: 53, Issue:4

    Topics: Acute Kidney Injury; Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Hypersensi

2014
[DRESS syndrome: Report of nine cases].
    Revista medica de Chile, 2015, Volume: 143, Issue:5

    Topics: Adolescent; Adult; Aged; Carbamazepine; Dexamethasone; Drug Hypersensitivity Syndrome; Eosinophilia;

2015
What is This Rash?
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016, Volume: 12, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Anticonvulsants; Drug Hypersensitivity Syndrome; Drug Substitution;

2016
Association of HLA-B*15:13 and HLA-B*15:02 with phenytoin-induced severe cutaneous adverse reactions in a Malay population.
    The pharmacogenomics journal, 2017, Volume: 17, Issue:2

    Topics: Anticonvulsants; Case-Control Studies; Drug Hypersensitivity Syndrome; Female; Gene Frequency; Genet

2017
Phenytoin induced DRESS syndrome.
    Indian journal of pediatrics, 2013, Volume: 80, Issue:3

    Topics: Anticonvulsants; Child; Drug Hypersensitivity Syndrome; Humans; Male; Phenytoin

2013
DRESS syndrome.
    BMJ case reports, 2012, Jul-03, Volume: 2012

    Topics: Administration, Oral; Adolescent; Anticonvulsants; Diagnosis, Differential; Drug Hypersensitivity Sy

2012
Case of drug-induced hypersensitivity syndrome with multiple skin ulcers caused by herpes simplex virus reactivation.
    The Journal of dermatology, 2013, Volume: 40, Issue:2

    Topics: Aged; Anticonvulsants; Drug Hypersensitivity Syndrome; Herpes Simplex; Humans; Male; Phenytoin; Simp

2013
DRESS syndrome and thrombotic thrombocytopaenic purpura: are they related?
    BMJ case reports, 2012, Nov-14, Volume: 2012

    Topics: ADAM Proteins; ADAMTS13 Protein; Anticonvulsants; Cerebral Infarction; Drug Hypersensitivity Syndrom

2012