phenytoin has been researched along with Craniofacial Abnormalities in 4 studies
Craniofacial Abnormalities: Congenital structural deformities, malformations, or other abnormalities of the cranium and facial bones.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy." | 9.08 | Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997) |
| " The boy was exposed to phenytoin, in combination with carbamazepine, during pregnancy." | 7.71 | Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy. ( Annerén, G; Brandberg, G; Larsson, M; Lönnerholm, T; Wester, U, 2002) |
| "Our objective was to evaluate the patterns of malformations in children exposed in utero to phenytoin (DPH) and carbamazepine (CBZ) monotherapy, and to compare them prospectively with matched mother-child pairs exposed to nonteratogens, and to separate the effects of antiepileptic drugs (AEDs) from those of epilepsy by collecting groups of untreated epileptics and those treated with DPH and CBZ for conditions other than epilepsy." | 5.08 | Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. ( Chitayat, D; Farkas, LD; Koren, G; Nulman, I; Scolnik, D, 1997) |
| " We studied 174 pregnancies in 155 women who used phenytoin throughout their pregnancy, gave birth to a live child and had available stored blood specimens suitable for DNA extraction." | 3.76 | Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations. ( Azzato, EM; Caporaso, NE; Chanock, SJ; Chen, RA; Klebanoff, MA; Wacholder, S, 2010) |
| " The boy was exposed to phenytoin, in combination with carbamazepine, during pregnancy." | 3.71 | Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy. ( Annerén, G; Brandberg, G; Larsson, M; Lönnerholm, T; Wester, U, 2002) |
| "She had growth retardation, mental deficiency, craniofacial dysmorphism and iris colomobata specific to FHS." | 1.30 | Polydactyly and fetal hydantoin syndrome: an additional component of the syndrome? ( Cenani, A; Somay, G; Tüysüz, B; Yalçinkaya, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azzato, EM | 1 |
| Chen, RA | 1 |
| Wacholder, S | 1 |
| Chanock, SJ | 1 |
| Klebanoff, MA | 1 |
| Caporaso, NE | 1 |
| Wester, U | 1 |
| Brandberg, G | 1 |
| Larsson, M | 1 |
| Lönnerholm, T | 1 |
| Annerén, G | 1 |
| Nulman, I | 1 |
| Scolnik, D | 1 |
| Chitayat, D | 1 |
| Farkas, LD | 1 |
| Koren, G | 1 |
| Yalçinkaya, C | 1 |
| Tüysüz, B | 1 |
| Somay, G | 1 |
| Cenani, A | 1 |
1 trial available for phenytoin and Craniofacial Abnormalities
| Article | Year |
|---|---|
Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications.
Topics: Adult; Carbamazepine; Cohort Studies; Craniofacial Abnormalities; Epilepsy; Female; Fingers; Humans; | 1997 |
3 other studies available for phenytoin and Craniofacial Abnormalities
| Article | Year |
|---|---|
Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Confidence Intervals; Craniofacial | 2010 |
Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Chondrodysplasia Punctata; Craniofacial Abnormalit | 2002 |
Polydactyly and fetal hydantoin syndrome: an additional component of the syndrome?
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child, Preschool; Craniofacial Abnormalities; | 1997 |