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phenytoin and Coronary Heart Disease

phenytoin has been researched along with Coronary Heart Disease in 42 studies

Research Excerpts

ExcerptRelevanceReference
"Serum low-density lipoprotein cholesterol and high-density lipoprotein cholesterol concentration and the ratio between them, major risk factors of coronary heart disease, and liver size were investigated in 18 subjects who were on enzyme-inducing anticonvulsants, phenytoin alone or in combination with phenobarbital and/or carbamazepine."3.67Serum low-density lipoprotein and high-density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes. ( Luoma, PV; Pelkonen, RO; Pirttiaho, HI; Sotaniemi, EA, 1985)
"The author describes the notions that led to initiation of controlled trials of long-term medication with antiarrhythmic drugs following myocardial infarction, and reviews reports of controlled trials with diphenylhydantoin, alprenolol, and procaine amide."3.65Arrhythmia prophylaxis: Long-term suppressive medication. ( Lovell, RR, 1975)
"After treatment of ischemia and/or failure, specific antiarrhythmic agents, conventional and investigational, alone or in combination, are systematically selected."1.26Ventricular ectopy: etiology, evaluation, and therapy. ( Reid, PR; Vlay, SC, 1982)
"For the therapy of disturbances of the cardiac rhythm with phenytoin 3 different dosage regimes are examined, in which cases an oral application of phenytoin proves as not suitable."1.26[Serum level determination in patients with acute myocardial infarction under diphenylhydantoin therapy]. ( Kettner, W; Quednow, B; Walther, H; Wilckens, H, 1979)
"Nine of these had ventricular arrhythmia refractory to drugs."1.25Atrial pacing to control heart rate and rhythm in acute cardiac conditions. ( Friesen, WG, 1971)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199038 (90.48)18.7374
1990's4 (9.52)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vlay, SC1
Reid, PR1
Hoffmann, A1
Schütz, E1
White, R1
Follath, F1
Burckhardt, D1
Ferro, G1
Chiariello, M1
Tari, MG1
Vigorito, C1
Ungaro, B1
Condorelli, M1
Winkle, RA2
Miller, M1
Burgan, RG1
Osterlund, L1
Segrest, JP1
Garber, DW1
Goerdt, C1
Keith, M1
Rubins, HB1
Quinn, MJ1
Fitzgerald, DJ1
Laurencet, FL1
Corr, PB1
Sobel, BE1
Lovell, RR1
D'Amato, PH1
Taylor, JB1
Rios, JC1
Breithardt, G1
Seipel, L1
Loogen, F1
Lown, B2
Temte, JV1
Reich, P1
Gaughan, C1
Regestein, Q1
Hal, H1
Kettner, W1
Quednow, B1
Wilckens, H1
Walther, H1
Alderman, EL1
Fitzgerald, JW1
Harrison, DC1
Hondeghem, LM2
al-Rubeaan, K1
Ryan, EA1
Maeda, M1
Kitamura, Y1
Takata, M1
Nakamura, Y1
Masuda, S1
Nishida, K1
Hata, F1
Okada, K1
Chinzei, T1
Yamashiro, K1
Lynch, J1
Montgomery, D1
Ventura, A1
Wilber, D1
Lucchesi, BR1
Muuronen, A1
Kaste, M1
Nikkilä, EA1
Tolppanen, EM1
Luoma, PV1
Sotaniemi, EA1
Pelkonen, RO1
Pirttiaho, HI1
Gebauer, D1
Helfant, RH1
Seuffert, GW1
Patton, RD1
Stein, E1
Damato, AN1
McCans, JL1
Brennan, FJ1
Chiong, MA1
Parker, JO1
Valère, PE1
Guérot, C1
Lancelin, B1
Tricot, R1
Rydén, L1
Hjalmarson, A1
Wasir, H1
Werkö, L1
Kones, RJ1
Phillips, JH1
Hersh, J1
Beck, OA1
Wolf, R1
Krämer, KD1
Hochrein, H1
Koch-Weser, J1
Atkinson, AJ1
Davison, R1
Cohen, H1
Langendorf, R1
Pick, A1
Leon-Sotomayor, LA1
Djonlagić, H1
von Kurnatowski, HA1
Diederich, KW1
Kobayashi, T1
Matsumoto, S1
Sloman, G1
Moccetti, T1
Lichtlen, P1
Casaccia, M1
Halter, J1
Mohr, P1
Stone, N1
Klein, MD1
Mckenna, G1
Engle, RP1
Brooks, H1
Dalen, J1
Dhurandhar, RW1
Teasdale, SJ1
Mahon, WA1
Friesen, WG1

Reviews

6 reviews available for phenytoin and Coronary Heart Disease

ArticleYear
Ticlopidine and clopidogrel.
    Circulation, 1999, Oct-12, Volume: 100, Issue:15

    Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angina, Unstable; Aspirin; Bo

1999
[Frequency, prognosis, and treatment of cardiac arrhythmias in coronary heart disease--a review (author's transl)].
    Zeitschrift fur Kardiologie, 1978, Volume: 67, Issue:1

    Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Disease; Germany, West; Humans; Phenyto

1978
Antiarrhythmic prophylaxis in ambulatory patients with coronary heart disease.
    Archives of internal medicine, 1972, Volume: 129, Issue:5

    Topics: Ambulatory Care; Arrhythmias, Cardiac; Coronary Disease; Humans; Injections, Intramuscular; Phenytoi

1972
Diphenylhydantoin as an antiarrhythmic drug.
    Annual review of medicine, 1974, Volume: 25

    Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Ca

1974
[The circulatory system].
    Naika. Internal medicine, 1969, Volume: 23, Issue:1

    Topics: Angiocardiography; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Cardiac Surgic

1969
Changing concepts in the care of patients with acute myocardial infarction.
    The Medical journal of Australia, 1969, Jun-07, Volume: 1, Issue:23

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Blood Gas Analysis; Bundle-Branch Block; Cardiac Output;

1969

Trials

2 trials available for phenytoin and Coronary Heart Disease

ArticleYear
A prospective, randomized trial of phenytoin in nonepileptic subjects with reduced HDL cholesterol.
    Arteriosclerosis, thrombosis, and vascular biology, 1995, Volume: 15, Issue:12

    Topics: Adult; Aged; Cholesterol, HDL; Coronary Disease; Double-Blind Method; Female; Humans; Lipids; Lipopr

1995
Effects of phenytoin on plasma high-density lipoprotein cholesterol levels in men with low levels of high-density lipoprotein cholesterol.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Cholesterol, HDL; Coronary Disease; Double-Blind Method; Drug Admini

1995

Other Studies

34 other studies available for phenytoin and Coronary Heart Disease

ArticleYear
Ventricular ectopy: etiology, evaluation, and therapy.
    The American journal of medicine, 1982, Volume: 73, Issue:6

    Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Aprindine; Arrhyth

1982
Suppression of high-grade ventricular ectopic activity by antiarrhythmic drug treatment as a marker for survival in patients with chronic coronary artery disease.
    American heart journal, 1984, Volume: 107, Issue:6

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Female; Hum

1984
Intropic effects of several antiarrhythmic drugs.
    Japanese heart journal, 1983, Volume: 24, Issue:3

    Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Blood Pressure; Bunaftine; Coronary Disease; Disopyrami

1983
Clinical efficacy of antiarrhythmic drugs in prevention of sudden coronary death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Angiography; Coronary Artery Bypas

1982
[Out patient prophylaxis of arrhythmias due to coronary insufficiency (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1976, Jan-20, Volume: 65, Issue:3

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Humans;

1976
Mechanisms contributing to dysrhythmias induced by ischemia and their therapeutic implications.
    Advances in cardiology, 1978, Issue:22

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease

1978
Arrhythmia prophylaxis: Long-term suppressive medication.
    Circulation, 1975, Volume: 52, Issue:6 Suppl

    Topics: Acute Disease; Aged; Alprenolol; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Diseas

1975
Should premature ventricular beats be treated in the ambulatory patient? An antagonist's view.
    Cardiovascular clinics, 1977, Volume: 8, Issue:1

    Topics: Adult; Aged; Cardiac Complexes, Premature; Coronary Disease; Death, Sudden; Electrocardiography; Fol

1977
Basis for recurring ventricular fibrillation in the absence of coronary heart disease and its management.
    The New England journal of medicine, 1976, Mar-18, Volume: 294, Issue:12

    Topics: Adult; Anti-Arrhythmia Agents; Coronary Disease; Digitalis Glycosides; Drug Therapy, Combination; El

1976
Plasma high-density lipoproteins.
    The New England journal of medicine, 1979, Apr-05, Volume: 300, Issue:14

    Topics: Age Factors; Animals; Coronary Disease; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lipoprote

1979
[Serum level determination in patients with acute myocardial infarction under diphenylhydantoin therapy].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Oct-15, Volume: 34, Issue:20

    Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Coronary Disease; Female;

1979
Treatment of recurrent symptomatic ventricular tachycardia.
    Annals of internal medicine, 1976, Volume: 85, Issue:1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Coronary Disease; Drug Evaluation; Female; He

1976
Effects of lidocaine, phenytoin and quinidine on the ischemic canine myocardium.
    Journal of electrocardiology, 1976, Volume: 9, Issue:3

    Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Electromyography; Heart Rate; Lidocaine; Phenytoin;

1976
Effects of quinidine, lidocaine and phenytoin on the excitability of the ischemic rabbit heart.
    Proceedings of the Western Pharmacology Society, 1976, Volume: 19

    Topics: Animals; Coronary Disease; Electrocardiography; Heart; Lidocaine; Phenytoin; Quinidine; Rabbits; Tim

1976
Phenytoin-induced insulin insensitivity.
    Diabetic medicine : a journal of the British Diabetic Association, 1991, Volume: 8, Issue:10

    Topics: Aged; Aged, 80 and over; C-Peptide; Coronary Artery Bypass; Coronary Disease; Epilepsies, Partial; H

1991
[A case of systemic lupus erythematosus demonstrating basal ganglia calcifications, coronary stenosis and selective IgA deficiency].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1986, Volume: 75, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Calcinosis; Coronary Disease; Dysgammaglobulinemia; Female; Humans; I

1986
Antiarrhythmic vs. antifibrillatory activity of the basic diphenylhydantoin derivative 3-[3-(4-phenyl-1-piperidyl)propyl]-5-(4-methoxyphenyl)-5-phenylhydantoin hydrochloride.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:3

    Topics: Anesthesia, General; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Co

1986
Mortality from ischaemic heart disease among patients using anticonvulsive drugs: a case-control study.
    British medical journal (Clinical research ed.), 1985, Nov-23, Volume: 291, Issue:6507

    Topics: Aged; Anticonvulsants; Barbiturates; Carbamazepine; Cardiovascular Diseases; Cerebrovascular Disorde

1985
Serum low-density lipoprotein and high-density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:6

    Topics: Adult; Carbamazepine; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cytochrome P-450 Enzyme

1985
[Prevention and therapy of cardiac rhythm disorders. Experiences with a diphenylhydantoin-meprobamate preparation (Cusitan)].
    Munchener medizinische Wochenschrift (1950), 1971, Mar-19, Volume: 113, Issue:12

    Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Pre

1971
The clinical use of diphenylhydantoin (dilantin) in the treatment and prevention of cardiac arrhythmias.
    American heart journal, 1969, Volume: 77, Issue:3

    Topics: Anesthesia, General; Anesthesia, Inhalation; Arrhythmias, Cardiac; Atrial Flutter; Blood Pressure De

1969
Effects of ouabain and diphenylhydantoin myocardial potassium balance in man.
    The American journal of cardiology, 1973, Volume: 31, Issue:3

    Topics: Adenosine Triphosphatases; Aortic Valve Stenosis; Blood Pressure; Cardiac Output; Cardiomyopathies;

1973
[Rhythmic disorders due to digitalis overdose].
    Annales de medecine interne, 1972, Volume: 123, Issue:3

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Arrhythmias, Cardiac; Coronary Disease; Digitalis Gl

1972
Effects of a long-acting antiarrhythmic agent--QX-572--on therapy resistant ventricular tachyarrhythmias.
    British heart journal, 1974, Volume: 36, Issue:8

    Topics: Acute Disease; Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure;

1974
Mechanism and management of chaotic atrial mechanism.
    Cardiology, 1974, Volume: 59, Issue:2

    Topics: Acute Disease; Chronic Disease; Coronary Disease; Digitalis Glycosides; Drug Therapy, Combination; E

1974
[Haemodynamic reactions to injection and subsequent infusion of phenytoin (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Nov-08, Volume: 99, Issue:45

    Topics: Blood Pressure; Cardiac Output; Cardiac Volume; Coronary Disease; Heart Rate; Hemodynamics; Humans;

1974
Intermittent parasystole--mechanism of protection.
    Circulation, 1973, Volume: 48, Issue:4

    Topics: Aged; Aminosalicylic Acids; Arrhythmias, Cardiac; Arteriosclerosis; Cerebrovascular Disorders; Coron

1973
Cardiac migraine--report of twelve cases.
    Angiology, 1974, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Angina Pectoris; Angiocardiography; Coronary Disease; Diazepam; Diet Therapy; Ele

1974
[Bidirectional tachycardia caused by digitalis (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Mar-15, Volume: 99, Issue:11

    Topics: Administration, Oral; Coronary Disease; Digoxin; Electrocardiography; Female; Heart Failure; Humans;

1974
[Cardiac toxicity of tricyclic antidepressants].
    Giornale italiano di cardiologia, 1972, Volume: 2, Issue:3

    Topics: Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Female; H

1972
Diphenylhydantoin in the prevention of recurring ventricular tachycardia.
    Circulation, 1971, Volume: 43, Issue:3

    Topics: Adult; Chronic Disease; Coronary Disease; Humans; Phenytoin

1971
Cardiac arrhythmias during electroshock therapy: significance, prevention, and treatment.
    The American journal of psychiatry, 1970, Volume: 127, Issue:4

    Topics: Acidosis, Respiratory; Aged; Arrhythmias, Cardiac; Blood Gas Analysis; Coronary Disease; Electrocard

1970
Bretylium tosylate in the management of refractory ventricular fibrillation.
    Canadian Medical Association journal, 1971, Jul-24, Volume: 105, Issue:2

    Topics: Adult; Age Factors; Aged; Angina Pectoris; Aortic Valve Insufficiency; Aortic Valve Stenosis; Bretyl

1971
Atrial pacing to control heart rate and rhythm in acute cardiac conditions.
    Canadian Medical Association journal, 1971, May-22, Volume: 104, Issue:10

    Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Volume; Bradycardia; Cardiac Catheterization

1971