Page last updated: 2024-10-21

phenytoin and Convulsive Generalized Seizure Disorder

phenytoin has been researched along with Convulsive Generalized Seizure Disorder in 62 studies

Research Excerpts

ExcerptRelevanceReference
"To compare the effectiveness of monotherapy clobazam (CLB) to carbamazepine (CBZ) and phenytoin (PHT) in children with epilepsy."9.08Clobazam has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy. Canadian Study Group for Childhood Epilepsy. ( , 1998)
"To evaluate the efficacy, effectiveness, tolerability and safety of clobazam as monotherapy in people with new-onset focal or generalized seizures."8.98Clobazam monotherapy for focal or generalized seizures. ( Anand, V; Arya, R; Garg, SK; Giridharan, N, 2018)
"To review the time to withdrawal, remission and first seizure of phenytoin compared to valproate when used as monotherapy in people with partial onset seizures or generalised tonic-clonic seizures (with or without other generalised seizure types)."8.93Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2016)
"To evaluate the efficacy, effectiveness, tolerability and safety of clobazam as monotherapy in people with new-onset partial or generalized seizures."8.90Clobazam monotherapy for partial-onset or generalized-onset seizures. ( Anand, V; Arya, R; Garg, SK; Michael, BD, 2014)
"To review the best evidence comparing phenytoin and valproate when used as monotherapy in individuals with partial onset seizures or generalised onset tonic-clonic seizures with or without other generalised seizure types."8.89Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures. ( Marson, AG; Nolan, SJ; Pulman, J; Tudur Smith, C, 2013)
"To review the best evidence comparing phenytoin and valproate when used as monotherapy in subjects with partial onset seizures, or generalized onset tonic-clonic seizures with or without other generalized seizure types."8.81Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures. ( Marson, AG; Tudur Smith, C; Williamson, PR, 2001)
"To review the effects of phenobarbitone compared to phenytoin when used as monotherapy in patients with partial onset seizures or generalized tonic-clonic seizures with or without other generalized seizure types."8.81Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalized onset tonic-clonic seizures. ( Marson, AG; Taylor, S; Tudur Smith, C; Williamson, PR, 2001)
"We report a case of young male presented with chorea after two months of starting phenytoin for primary generalised epilepsy with normal therapeutic serum drug level."7.91Phenytoin Induced Chorea: A Rare Adverse Effect of the Drug. ( Gurumukhani, JK; Patel, DM; Patel, GR; Patel, MV, 2019)
"To compare the frequency of seizures and status epilepticus and their response to first-line drugs in patients with idiopathic generalized epilepsies receiving carbamazepine or phenytoin to those receiving other drugs or no treatment."7.70Refractory idiopathic absence status epilepticus: A probable paradoxical effect of phenytoin and carbamazepine. ( Osorio, I; Peltzer, JN; Reed, RC, 2000)
"Valproic acid induced coma is presented in an adult patient without a history of metabolic disease."7.68Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma. ( Colombo, JP; Straver, JS; van der Vijver, JC; van Woerkom, TC; Verbiest, HB, 1992)
"To compare the effectiveness of monotherapy clobazam (CLB) to carbamazepine (CBZ) and phenytoin (PHT) in children with epilepsy."5.08Clobazam has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy. Canadian Study Group for Childhood Epilepsy. ( , 1998)
"To evaluate the efficacy, effectiveness, tolerability and safety of clobazam as monotherapy in people with new-onset focal or generalized seizures."4.98Clobazam monotherapy for focal or generalized seizures. ( Anand, V; Arya, R; Garg, SK; Giridharan, N, 2018)
"Randomised controlled trials (RCTs) comparing monotherapy with either sodium valproate or phenytoin in children or adults with focal onset seizures or generalised onset tonic-clonic seizures DATA COLLECTION AND ANALYSIS: This was an individual participant data (IPD) review."4.98Sodium valproate versus phenytoin monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nevitt, SJ; Tudur Smith, C; Weston, J, 2018)
"To review the time to withdrawal, remission and first seizure of phenytoin compared to valproate when used as monotherapy in people with partial onset seizures or generalised tonic-clonic seizures (with or without other generalised seizure types)."4.93Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2016)
"To evaluate the efficacy, effectiveness, tolerability and safety of clobazam as monotherapy in people with new-onset partial or generalized seizures."4.90Clobazam monotherapy for partial-onset or generalized-onset seizures. ( Anand, V; Arya, R; Garg, SK; Michael, BD, 2014)
"To review the best evidence comparing phenytoin and valproate when used as monotherapy in individuals with partial onset seizures or generalised onset tonic-clonic seizures with or without other generalised seizure types."4.89Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures. ( Marson, AG; Nolan, SJ; Pulman, J; Tudur Smith, C, 2013)
"In this systematic review we present information relating to the effectiveness and safety of the following interventions: monotherapy using carbamazepine, gabapentin, lamotrigine, levetiracetam, phenobarbital, phenytoin, sodium valproate, or topiramate; addition of second-line drugs (lamotrigine or levetiracetam) for drug-resistant epilepsy; and hemispherectomy for drug-resistant epilepsy."4.88Epilepsy (generalised). ( Maguire, M; Marson, AG; Ramaratnam, S, 2012)
"In this systematic review we present information relating to the effectiveness and safety of the following interventions: monotherapy using carbamazepine, gabapentin, lamotrigine, levetiracetam, phenobarbital, phenytoin, sodium valproate, or topiramate; addition of second-line drugs (lamotrigine or levetiracetam) for drug-resistant epilepsy; and hemispherectomy for drug-resistant epilepsy."4.86Epilepsy (generalised). ( Maguire, M; Marson, AG; Ramaratnam, S, 2010)
"To review the best evidence comparing phenytoin and valproate when used as monotherapy in subjects with partial onset seizures, or generalized onset tonic-clonic seizures with or without other generalized seizure types."4.81Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures. ( Marson, AG; Tudur Smith, C; Williamson, PR, 2001)
"To review the effects of phenobarbitone compared to phenytoin when used as monotherapy in patients with partial onset seizures or generalized tonic-clonic seizures with or without other generalized seizure types."4.81Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalized onset tonic-clonic seizures. ( Marson, AG; Taylor, S; Tudur Smith, C; Williamson, PR, 2001)
"We report a case of young male presented with chorea after two months of starting phenytoin for primary generalised epilepsy with normal therapeutic serum drug level."3.91Phenytoin Induced Chorea: A Rare Adverse Effect of the Drug. ( Gurumukhani, JK; Patel, DM; Patel, GR; Patel, MV, 2019)
"From 100 consecutive epilepsy patients we selected those with phenytoin use for more than 2 months and with MRI scan available for volumetric studies."3.72Cerebellar volume and long-term use of phenytoin. ( Cendes, F; De Marcos, FA; Ghizoni, E; Kobayashi, E; Li, LM, 2003)
"To compare the frequency of seizures and status epilepticus and their response to first-line drugs in patients with idiopathic generalized epilepsies receiving carbamazepine or phenytoin to those receiving other drugs or no treatment."3.70Refractory idiopathic absence status epilepticus: A probable paradoxical effect of phenytoin and carbamazepine. ( Osorio, I; Peltzer, JN; Reed, RC, 2000)
" Following treatment with antiepileptic drugs (AEDs), the patient developed several rare complications: after beginning therapy with phenytoin, the patient developed pseudolymphoma; after monotherapy with carbamazepine (CBZ), the patient thereafter developed myoclonic jerks of upper and lower limbs upon awakening; after one year of treatment with valproate (VPA) the patient developed clinical and immuno-haematological signs of SLE."3.69Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p. ( Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G, 1996)
"Valproic acid induced coma is presented in an adult patient without a history of metabolic disease."3.68Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma. ( Colombo, JP; Straver, JS; van der Vijver, JC; van Woerkom, TC; Verbiest, HB, 1992)
"Phenytoin is a prototypic drug prescribed for the treatment of a variety of seizure disorders."3.01Cutaneous Hypersensitivity Reaction After Phenytoin Therapy in a Neonate: A Case Report and Review of Literature Elucidating the Potential Pharmacological Plausibility and Preventive Strategies. ( Prabath, I; Rajendran, P; Rani, J, 2023)
"Ninety four patients of generalised and partial epilepsy were randomly assigned to treatment with sodium valproate (49 cases) or phenytoin (45 cases)."2.67Comparison of sodium valproate and phenytoin as single drug treatment in generalised and partial epilepsy. ( Agarwala, RK; Mehrotra, TN; Rastogi, P; Singh, VS, 1991)
"Epilepsy is a common neurological condition with a worldwide prevalence of around 1%."2.55Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. ( Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J, 2017)
"Epilepsy is a common neurological condition with a worldwide prevalence of around 1%."2.55Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. ( Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J, 2017)
"Carbamazepine is a current first-line treatment for partial onset seizures in the USA and Europe."2.55Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nevitt, SJ; Tudur Smith, C; Weston, J, 2017)
"Carbamazepine is a current first line treatment for partial onset seizures in the USA and Europe."2.52Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2015)
"Topiramate was more likely prescribed for those with comorbid headache or migraine (incident: 335 of 1251 [26."1.51Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy. ( Faught, E; Fishman, J; Kalilani, L; Kim, H; Thurman, DJ, 2019)
"Propofol was the most prescribed third-line treatment."1.40A retrospective observational study of current treatment for generalized convulsive status epilepticus. ( Fountain, NB; Langer, JE, 2014)
"Among those with Idiopathic Generalized Epilepsy (46%), generalized tonic clonic seizure was encountered in 74% and absence seizure was observed in 13%."1.39Antiepileptic drug utilization in Bangladesh: experience from Dhaka Medical College Hospital. ( Chowdhury, AH; Chowdhury, RN; Ghose, SK; Habib, M; Haque, B; Hasan, AT; Hoque, A; Khan, SU; Mohammad, QD; Mondal, BA; Rahman, KM, 2013)
"Epilepsy is a relatively common problem in children, adults and the elderly."1.30Treatment of the epileptic patient in the dental office. ( Haller, JS; Kennedy, BT, 1998)
"When phenytoin was discontinued, valproate levels increased, and he progressively improved."1.30Exceptionally long absence status: multifactorial etiology, drug interactions and complications. ( Andermann, F; Bastos, A; D'Agostino, MD; Dubeau, F; Fedi, M, 1999)
"Idiopathic generalized epilepsy (IGE) was diagnosed in 12 cases and partial epilepsy (PE) in 23 cases."1.29Sex hormones, gonadotropins and prolactin in male epileptic subjects in remission: role of the epileptic syndrome and of antiepileptic drugs. ( Costelli, P; Fonzi, S; Galimberti, CA; Manni, R; Murialdo, G; Parodi, C; Polleri, A; Solinas, GP; Tartara, A; Torre, F, 1994)
" We consider his cerebellar symptoms and peripheral neuropathy could be attributable to the long-term use of multiple anticonvulsants, i."1.29[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy]. ( Kubota, M; Nagata, J, 1993)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's28 (45.16)18.2507
2000's8 (12.90)29.6817
2010's23 (37.10)24.3611
2020's3 (4.84)2.80

Authors

AuthorsStudies
Rajendran, P1
Prabath, I1
Rani, J1
Dang, LT1
Quinonez, SC1
Becka, BR1
Isom, LL1
Joshi, SM1
Wu, K1
Hirsch, LJ2
Babl, FE1
Josephson, SA1
Nevitt, SJ4
Sudell, M2
Weston, J6
Tudur Smith, C9
Marson, AG11
Husain, AM1
Lee, JW1
Kolls, BJ1
Halford, JJ1
Gupta, PK1
Minazad, Y1
Jones, JM1
LaRoche, SM1
Herman, ST1
Swisher, CB1
Sinha, SR1
Palade, A1
Dombrowski, KE1
Gallentine, WB1
Hahn, CD1
Gerard, EE1
Bhapkar, M1
Lokhnygina, Y1
Westover, MB1
Arya, R2
Giridharan, N1
Anand, V2
Garg, SK2
Patel, DM1
Gurumukhani, JK1
Patel, MV1
Patel, GR1
Kim, H1
Faught, E1
Thurman, DJ1
Fishman, J1
Kalilani, L1
Wendell, LC1
Potter, NS1
Roth, JL1
Salloway, SP1
Thompson, BB1
Ekici, MA1
Ekici, A1
Ozdemir, O1
Nolan, SJ3
Pulman, J1
Habib, M1
Khan, SU1
Hoque, A1
Mondal, BA1
Hasan, AT1
Chowdhury, RN1
Haque, B1
Rahman, KM1
Chowdhury, AH1
Ghose, SK1
Mohammad, QD1
Cheuk, DK1
Wong, V1
Langer, JE1
Fountain, NB1
Michael, BD1
Mundlamuri, RC1
Sinha, S1
Subbakrishna, DK1
Prathyusha, PV1
Nagappa, M1
Bindu, PS1
Taly, AB1
Umamaheswara Rao, GS1
Satishchandra, P1
Maguire, M2
Ramaratnam, S2
Igelström, KM1
Shirley, CH1
Heyward, PM1
Naha, K1
Dasari, S1
Vivek, G1
Prabhu, M1
Ovallath, S1
Remya, RK1
Kumar, C1
Nayanar, S1
De Marcos, FA1
Ghizoni, E1
Kobayashi, E1
Li, LM1
Cendes, F1
Brickell, K1
Porter, D1
Thompson, P1
Roach, A1
Roach, E1
Zenkov, LR1
Heller, AJ1
Chesterman, P1
Elwes, RD1
Crawford, P1
Chadwick, D1
Johnson, AL2
Reynolds, EH1
Callaghan, N1
Majeed, T1
O'Connell, A1
Oliveira, DB1
Murialdo, G1
Galimberti, CA1
Fonzi, S1
Manni, R1
Costelli, P1
Parodi, C1
Torre, F1
Solinas, GP1
Polleri, A1
Tartara, A1
Reutens, DC1
Duncan, JS1
Patsalos, PN1
Ono, K1
Baba, H1
Sugai, S1
Gao, L1
Zhou, S1
Wang, J1
Kubota, M1
Nagata, J1
Cascino, GD1
Shulman, LM1
Singer, C1
Weiner, WJ1
Gigli, GL1
Scalise, A1
Silvestri, G1
Diomedi, M1
Placidi, F1
Pomponi, MG1
Masala, C1
Misra, UK1
Kalita, J1
Babu, GN1
Dwivedi, KD1
Knoll, B1
Haefeli, WE1
Ladewig, D1
Stohler, R1
Applegate, CD1
Samoriski, GM1
Ozduman, K1
Kato, H1
Kishikawa, H1
Emura, S1
Takashima, T1
Ohmori, K1
Fujita, H1
Bill, PA1
Vigonius, U2
Pohlmann, H2
Guerreiro, CA1
Kochen, S1
Saffer, D1
Moore, A2
Guerreiro, MM1
de Manreza, ML1
Fejerman, N1
Antoniuk, SA1
Pal, DK1
Das, T1
Chaudhury, G1
Neville, BG1
Kennedy, BT1
Haller, JS1
Yoshida, M1
Kuroda, Y1
Yoshida, T1
Kobayashi, Y1
Yoshino, A1
Supprian, T1
Retz, W1
Deckert, J1
Osorio, I1
Reed, RC1
Peltzer, JN1
D'Agostino, MD1
Andermann, F1
Dubeau, F1
Fedi, M1
Bastos, A1
Kmieć, T1
Jóźwiak, S1
Kuczyński, D1
Karkowska, B1
Bachański, M1
Williamson, PR2
Taylor, S1
McKee, PJ1
Percy-Robb, I1
Brodie, MJ1
Verbiest, HB1
Straver, JS1
Colombo, JP1
van der Vijver, JC1
van Woerkom, TC1
Suzuki, T1
Koizumi, J1
Moroji, T1
Shiraishi, H1
Hori, T1
Baba, A1
Kawai, N1
Tada, K1
Rastogi, P1
Mehrotra, TN1
Agarwala, RK1
Singh, VS1
Altschuler, EM1
Segal, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness and Safety of Thread Embedding Acupuncture for Drug Resistant Epilepsy: a Randomized Clinical Trial[NCT04673071]60 participants (Anticipated)Interventional2020-11-17Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

16 reviews available for phenytoin and Convulsive Generalized Seizure Disorder

ArticleYear
Cutaneous Hypersensitivity Reaction After Phenytoin Therapy in a Neonate: A Case Report and Review of Literature Elucidating the Potential Pharmacological Plausibility and Preventive Strategies.
    Current drug safety, 2023, Volume: 18, Issue:4

    Topics: Anticonvulsants; Child; Drug Hypersensitivity; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized;

2023
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 06-29, Volume: 6

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Parti

2017
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 12-15, Volume: 12

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Parti

2017
Clobazam monotherapy for focal or generalized seizures.
    The Cochrane database of systematic reviews, 2018, 07-11, Volume: 7

    Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Clobazam; Epilepsies, Par

2018
Sodium valproate versus phenytoin monotherapy for epilepsy: an individual participant data review.
    The Cochrane database of systematic reviews, 2018, 08-09, Volume: 8

    Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenytoin; Randomized Controlle

2018
Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures.
    The Cochrane database of systematic reviews, 2013, Aug-23, Issue:8

    Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Phenyto

2013
Acupuncture for epilepsy.
    The Cochrane database of systematic reviews, 2014, May-07, Issue:5

    Topics: Acupuncture Therapy; Anticonvulsants; Child; Combined Modality Therapy; Drugs, Chinese Herbal; Epile

2014
Clobazam monotherapy for partial-onset or generalized-onset seizures.
    The Cochrane database of systematic reviews, 2014, Oct-04, Issue:10

    Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Clobazam; Epilepsies, Par

2014
Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review.
    The Cochrane database of systematic reviews, 2015, Aug-14, Issue:8

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Humans; In

2015
Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures: an individual participant data review.
    The Cochrane database of systematic reviews, 2016, Apr-28, Volume: 4

    Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Phenyto

2016
Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review.
    The Cochrane database of systematic reviews, 2017, 02-27, Volume: 2

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Humans; In

2017
Epilepsy (generalised).
    BMJ clinical evidence, 2010, Jun-22, Volume: 2010

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Generalized; Humans; Incidence; Phenytoin; Remis

2010
Epilepsy (generalised).
    BMJ clinical evidence, 2012, Feb-20, Volume: 2012

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Generalized; Humans; Incidence; Phenytoin; Remis

2012
How to assess phenytoin levels.
    Nursing, 2005, Volume: 35, Issue:11

    Topics: Adult; Anticonvulsants; Drug Interactions; Emergency Nursing; Epilepsy, Generalized; Female; Humans;

2005
Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenytoin; Randomized Controlle

2001
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenobarbital; Phenytoin; Rando

2001

Trials

9 trials available for phenytoin and Convulsive Generalized Seizure Disorder

ArticleYear
Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures.
    Annals of neurology, 2018, Volume: 83, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain Waves; Cross-Over Studies; Electroencephalogr

2018
Management of generalised convulsive status epilepticus (SE): A prospective randomised controlled study of combined treatment with intravenous lorazepam with either phenytoin, sodium valproate or levetiracetam--Pilot study.
    Epilepsy research, 2015, Volume: 114

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Epileps

2015
Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomised comparative monotherapy trial.
    Journal of neurology, neurosurgery, and psychiatry, 1995, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Aged; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female;

1995
A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy.
    Epilepsy research, 1997, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Double-Blind Method; Epi

1997
A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy.
    Epilepsy research, 1997, Volume: 27, Issue:3

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Double-Blind Method; Epilepsies

1997
Randomised controlled trial to assess acceptability of phenobarbital for childhood epilepsy in rural India.
    Lancet (London, England), 1998, Jan-03, Volume: 351, Issue:9095

    Topics: Adolescent; Anticonvulsants; Child; Child Behavior Disorders; Child, Preschool; Developing Countries

1998
Clobazam has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy. Canadian Study Group for Childhood Epilepsy.
    Epilepsia, 1998, Volume: 39, Issue:9

    Topics: Adolescent; Age Factors; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; C

1998
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
    Neurologia i neurochirurgia polska, 2000, Volume: 34 Suppl 7

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combi

2000
Comparison of sodium valproate and phenytoin as single drug treatment in generalised and partial epilepsy.
    The Journal of the Association of Physicians of India, 1991, Volume: 39, Issue:8

    Topics: Adolescent; Adult; Child; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Male; Middle A

1991

Other Studies

37 other studies available for phenytoin and Convulsive Generalized Seizure Disorder

ArticleYear
Dramatic Improvement in Seizures With Phenytoin Treatment in an Individual With Refractory Epilepsy and a SCN1B Variant.
    Pediatric neurology, 2020, Volume: 108

    Topics: Anticonvulsants; Child, Preschool; Drug Resistant Epilepsy; Electroencephalography; Epilepsy, Genera

2020
Choosing Anticonvulsant Medications to Manage Status Epilepticus.
    The New England journal of medicine, 2020, 06-25, Volume: 382, Issue:26

    Topics: Adult; Anticonvulsants; Disease Management; Drug Therapy, Combination; Epilepsy, Generalized; Female

2020
Phenytoin Induced Chorea: A Rare Adverse Effect of the Drug.
    Current drug safety, 2019, Volume: 14, Issue:1

    Topics: Anticonvulsants; Chorea; Epilepsy, Generalized; Humans; Male; Phenytoin; Young Adult

2019
Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.
    JAMA neurology, 2019, 07-01, Volume: 76, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Anxiety Disorders; Comorbidity; Dissociative Disorders; Epilepsi

2019
Successful management of severe neuroinvasive eastern equine encephalitis.
    Neurocritical care, 2013, Volume: 19, Issue:1

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antiviral Agents; Brain Edema; Encephalomyelitis, Eastern Eq

2013
Phenytoin-induced stuttering: an extremely rare association.
    Pediatric neurology, 2013, Volume: 49, Issue:2

    Topics: Anticonvulsants; Child, Preschool; Epilepsy, Generalized; Humans; Male; Phenytoin; Stuttering

2013
Antiepileptic drug utilization in Bangladesh: experience from Dhaka Medical College Hospital.
    BMC research notes, 2013, Nov-18, Volume: 6

    Topics: Adolescent; Adult; Anticonvulsants; Bangladesh; Carbamazepine; Child; Drug Combinations; Epilepsies,

2013
A retrospective observational study of current treatment for generalized convulsive status epilepticus.
    Epilepsy & behavior : E&B, 2014, Volume: 37

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Dru

2014
Low-magnesium medium induces epileptiform activity in mouse olfactory bulb slices.
    Journal of neurophysiology, 2011, Volume: 106, Issue:5

    Topics: Action Potentials; Acute Disease; Animals; Animals, Outbred Strains; Anticonvulsants; Culture Media;

2011
Vitamin B₁₂ deficiency: an unusual cause for recurrent generalised seizures with pancytopaenia.
    BMJ case reports, 2012, Sep-03, Volume: 2012

    Topics: Aged; Anticonvulsants; Cerebral Ventricles; Diagnosis, Differential; Drug Substitution; Epilepsy, Ge

2012
Granulomatous lymphadenopathy secondary to phenytoin therapy.
    Seizure, 2013, Volume: 22, Issue:3

    Topics: Anticonvulsants; Epilepsy, Generalized; Female; Humans; Lymphatic Diseases; Middle Aged; Phenytoin

2013
Cerebellar volume and long-term use of phenytoin.
    Seizure, 2003, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Cerebellum; Child; Child, Preschool; Dose-Response Relatio

2003
Phenytoin toxicity due to fluoropyrimidines (5FU/capecitabine): three case reports.
    British journal of cancer, 2003, Aug-18, Volume: 89, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Aged; Anticonvulsants; Antimetabolites, Antineoplastic; Breast

2003
[Anticonvulsive pharmacotherapy may aggravate epilepsy course].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2005, Volume: 105, Issue:10

    Topics: Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy;

2005
A comparative study of serum F protein and other liver function tests as an index of hepatocellular damage in epileptic patients.
    Acta neurologica Scandinavica, 1994, Volume: 89, Issue:4

    Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Aspartate Aminotransferases; Carbamazepine; Chemical a

1994
Sex hormones, gonadotropins and prolactin in male epileptic subjects in remission: role of the epileptic syndrome and of antiepileptic drugs.
    Neuropsychobiology, 1994, Volume: 30, Issue:1

    Topics: Adult; Androstenedione; Anticonvulsants; Carbamazepine; Dihydrotestosterone; Epilepsies, Partial; Ep

1994
Disabling tremor after lamotrigine with sodium valproate.
    Lancet (London, England), 1993, Jul-17, Volume: 342, Issue:8864

    Topics: Anticonvulsants; Drug Interactions; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigi

1993
A new chronic model of spontaneous nonconvulsive generalized seizures.
    The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2

    Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Corpus Callosum; Electroencephalography; Epilepsy, Absenc

1993
[The effects of phenytoin and carbamazepine on the cognitive function of epileptic patients].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1993, Volume: 24, Issue:3

    Topics: Attention; Carbamazepine; Cognition; Epilepsy, Generalized; Humans; Memory; Phenytoin

1993
[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy].
    No to shinkei = Brain and nerve, 1993, Volume: 45, Issue:7

    Topics: Adult; Anticonvulsants; Brain; Cerebellar Ataxia; Drug Therapy, Combination; Epilepsy, Generalized;

1993
Generalized convulsive status epilepticus.
    Mayo Clinic proceedings, 1996, Volume: 71, Issue:8

    Topics: Adolescent; Adult; Aged; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy, Generalized

1996
Phenytoin-induced focal chorea.
    Movement disorders : official journal of the Movement Disorder Society, 1996, Volume: 11, Issue:1

    Topics: Aged; Anticonvulsants; Athetosis; Basal Ganglia Diseases; Chorea; Epilepsy, Generalized; Humans; Mag

1996
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
    The International journal of neuroscience, 1996, Volume: 87, Issue:3-4

    Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromoso

1996
Clinical psychometry and P3 in patients on phenytoin monotherapy.
    Electromyography and clinical neurophysiology, 1997, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Epilepsy, Generalized; Event-Related Potentials, P300; Female; Humans; Male; Phen

1997
Early recurrence of withdrawal symptoms under phenytoin and chronic alcohol use.
    Pharmacopsychiatry, 1997, Volume: 30, Issue:2

    Topics: Adult; Alcoholism; Epilepsy, Generalized; Humans; Male; Methadone; Opioid-Related Disorders; Phenyto

1997
Effects of valproate, phenytoin, and MK-801 in a novel model of epileptogenesis.
    Epilepsia, 1997, Volume: 38, Issue:6

    Topics: Animals; Anticonvulsants; Behavior, Animal; Brain Stem; Disease Models, Animal; Dizocilpine Maleate;

1997
Treatment of focal status epilepticus with lignocaine.
    Journal of accident & emergency medicine, 1997, Volume: 14, Issue:3

    Topics: Aged; Anticonvulsants; Diazepam; Epilepsies, Partial; Epilepsy, Generalized; Humans; Lidocaine; Male

1997
Treatment of the epileptic patient in the dental office.
    The New York state dental journal, 1998, Volume: 64, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dental Care for Chronically Ill; Emergencies; Ep

1998
Epileptic falling spells after epidural haematoma in adult Down's syndrome.
    Brain injury, 1999, Volume: 13, Issue:3

    Topics: Adult; Anticonvulsants; Down Syndrome; Electroencephalography; Epilepsy, Generalized; Functional Lat

1999
[A case of inv dup (15) mosaic with mental retardation and symptomatic generalized epilepsy].
    No to shinkei = Brain and nerve, 1999, Volume: 51, Issue:3

    Topics: Adult; Anticonvulsants; Chromosomes, Human, Pair 15; Epilepsy, Generalized; Female; Humans; Intellec

1999
Clozapine-induced stuttering: epileptic brain activity?
    The American journal of psychiatry, 1999, Volume: 156, Issue:10

    Topics: Anticonvulsants; Antipsychotic Agents; Brain; Clozapine; Dose-Response Relationship, Drug; Electroen

1999
Refractory idiopathic absence status epilepticus: A probable paradoxical effect of phenytoin and carbamazepine.
    Epilepsia, 2000, Volume: 41, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Res

2000
Exceptionally long absence status: multifactorial etiology, drug interactions and complications.
    Epileptic disorders : international epilepsy journal with videotape, 1999, Volume: 1, Issue:4

    Topics: Aged; Anticonvulsants; Brain Ischemia; Dementia, Vascular; Drug Interactions; Epilepsy, Generalized;

1999
Therapeutic drug monitoring improves seizure control and reduces anticonvulsant side-effects in patients with refractory epilepsy.
    Seizure, 1992, Volume: 1, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Monitoring; Electroencephalog

1992
Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma.
    Acta neurologica Scandinavica, 1992, Volume: 86, Issue:3

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Atrophy; Carbamoyl-Phosphate Synthase (Ammonia

1992
Effects of long-term anticonvulsant therapy on copper, zinc, and magnesium in hair and serum of epileptics.
    Biological psychiatry, 1992, Mar-15, Volume: 31, Issue:6

    Topics: Adult; Anticonvulsants; Carbamazepine; Copper; Drug Therapy, Combination; Epilepsy, Generalized; Fem

1992
Generalized seizures following myelography with iohexol (Omnipaque).
    Journal of spinal disorders, 1990, Volume: 3, Issue:1

    Topics: Electromyography; Epilepsy, Generalized; Fractures, Bone; Humans; Humerus; Iohexol; Male; Middle Age

1990