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phenytoin and Convulsions, Febrile

phenytoin has been researched along with Convulsions, Febrile in 29 studies

Research Excerpts

ExcerptRelevanceReference
"Fosphenytoin (fPHT) and continuous intravenous midazolam (cMDL) had commonly been used as second-line treatments for pediatric status epilepticus (SE) in Japan."7.88Fosphenytoin vs. continuous midazolam for pediatric febrile status epilepticus. ( Fujita, K; Iijima, K; Ishida, Y; Kurosawa, H; Maruyama, A; Morioka, I; Nagase, H; Nishiyama, M; Nozu, K; Takada, S; Tanaka, T; Taniguchi-Ikeda, M; Tomioka, K; Toyoshima, D; Uetani, Y; Yamaguchi, H, 2018)
"The aim of this study was to determine the efficacy of phenytoin, a sodium channel blocker, in the treatment of febrile status epilepticus in children."7.78Lack of efficacy of phenytoin in children presenting with febrile status epilepticus. ( Carmant, L; Ismail, S; Lévy, A; Sévère, M; Tikkanen, H; Wolters, FJ, 2012)
"Fosphenytoin (fPHT) and continuous intravenous midazolam (cMDL) had commonly been used as second-line treatments for pediatric status epilepticus (SE) in Japan."3.88Fosphenytoin vs. continuous midazolam for pediatric febrile status epilepticus. ( Fujita, K; Iijima, K; Ishida, Y; Kurosawa, H; Maruyama, A; Morioka, I; Nagase, H; Nishiyama, M; Nozu, K; Takada, S; Tanaka, T; Taniguchi-Ikeda, M; Tomioka, K; Toyoshima, D; Uetani, Y; Yamaguchi, H, 2018)
"The aim of this study was to determine the efficacy of phenytoin, a sodium channel blocker, in the treatment of febrile status epilepticus in children."3.78Lack of efficacy of phenytoin in children presenting with febrile status epilepticus. ( Carmant, L; Ismail, S; Lévy, A; Sévère, M; Tikkanen, H; Wolters, FJ, 2012)
"Phenytoin was an ineffective prophylactic agent."2.65Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions. ( Bacon, CJ; Hierons, AM; Mucklow, JC; Rawlins, MD; Webb, JK; Weightman, D, 1981)
"Consequently, interventions to prevent seizures early in the course of a seizures disorder do not alter the natural history of seizure disorders with respect to whether remission will occur in the long term."2.40Do seizures beget seizures? An assessment of the clinical evidence in humans. ( Berg, AT; Shinnar, S, 1997)
"The risk of recurrences was significantly lower in children receiving continuous phenobarbital therapy than placebo (odds ratio 0."2.40A meta-analytic review of the preventive treatment of recurrences of febrile seizures. ( Rantala, H; Tarkka, R; Uhari, M, 1997)
"Severe myoclonic epilepsy of infancy (SMEI, also known as Dravet syndrome) and genetic epilepsy with febrile seizures plus (mild febrile seizures) can both arise due to mutations of SCN1A, the gene encoding alpha 1 pore-forming subunit of the Nav1."1.39Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons. ( Chen, J; Fan, Y; Gao, R; Gao, S; Jiao, J; Liao, W; Shi, Y; Sun, XF; Yang, Y; Yao, H, 2013)
"One hundred twenty-seven cases of seizure (86 GS and 41 FS) patients were analyzed for MDR1 C3435T and GABRG2 C588T gene polymorphisms using restriction fragment length polymorphism-polymerase chain reaction."1.38Role of MDR1 C3435T and GABRG2 C588T gene polymorphisms in seizure occurrence and MDR1 effect on anti-epileptic drug (phenytoin) absorption. ( Bhiladvala, D; Chaudhari, JR; Das, UN; Hasan, Q; Jaleel, MA; Kaipa, PR; Ponnala, S, 2012)
"Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given."1.27[Pharmacotherapy of epilepsy--current problems and controversies]. ( Schmidt, D, 1983)
" Saliva samples were easily obtained and the measured concentrations were a valuable guide to drug dosage during the treatment period."1.26Monitoring of phenobarbitone and phenytoin therapy in small children by salivary samples. ( Bacon, CJ; Hierons, AM; Mucklow, JC; Rawlins, MD; Webb, JK, 1981)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199018 (62.07)18.7374
1990's2 (6.90)18.2507
2000's3 (10.34)29.6817
2010's5 (17.24)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Ragavendran, JV1
Sriram, D1
Kotapati, S1
Stables, J1
Yogeeswari, P1
Dang, LT1
Quinonez, SC1
Becka, BR1
Isom, LL1
Joshi, SM1
Nishiyama, M1
Nagase, H1
Tomioka, K1
Tanaka, T1
Yamaguchi, H1
Ishida, Y1
Toyoshima, D1
Fujita, K1
Maruyama, A1
Kurosawa, H1
Uetani, Y1
Nozu, K1
Taniguchi-Ikeda, M1
Morioka, I1
Takada, S1
Iijima, K1
Jiao, J1
Yang, Y1
Shi, Y1
Chen, J1
Gao, R1
Fan, Y1
Yao, H1
Liao, W1
Sun, XF1
Gao, S1
Ponnala, S1
Chaudhari, JR1
Jaleel, MA1
Bhiladvala, D1
Kaipa, PR1
Das, UN1
Hasan, Q1
Ismail, S1
Lévy, A1
Tikkanen, H1
Sévère, M1
Wolters, FJ1
Carmant, L1
Pujar, SS1
Scott, RC1
Chin, RF1
FRANTZEN, E1
NYGAARD, A1
WULFF, H1
Bacon, CJ3
Hierons, AM3
Mucklow, JC2
Webb, JK3
Rawlins, MD3
Weightman, D1
Nowack, WJ2
Johnson, RN2
Hanna, GR2
Johnson, DD1
Crawford, KD1
Crawford, RD1
Schmidt, D1
Olson, JE1
Scher, MS1
Holtzman, D1
Gram, L1
Bentsen, KD1
Cranage, JD1
Berg, AT1
Shinnar, S1
Rantala, H1
Tarkka, R1
Uhari, M1
Lees, GV1
Jones, EG1
McNamara, J1
Autret-Leca, E1
Ployet, JL1
Jonville-Bera, AP1
Barry, JE1
Fishman, MA1
Livingston, S1
Pauli, LL1
Pruce, I1
Kramer, II1
Swanson, PD1
Wolf, SM1
Wässer, S1
Wässer, R1
Herranz Fernández, JL1

Reviews

4 reviews available for phenytoin and Convulsions, Febrile

ArticleYear
Do seizures beget seizures? An assessment of the clinical evidence in humans.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 1997, Volume: 14, Issue:2

    Topics: Anticonvulsants; Brain Injuries; Epilepsies, Myoclonic; Humans; Phenytoin; Seizures; Seizures, Febri

1997
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
    The Journal of pediatrics, 1997, Volume: 131, Issue:6

    Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Huma

1997
Febrile seizures: the treatment controversy.
    The Journal of pediatrics, 1979, Volume: 94, Issue:2

    Topics: Child; Epilepsy; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Recurrence; Seizures; Se

1979
Febrile convulsions: diagnosis, treatment, and prognosis.
    Pediatric annals, 1979, Volume: 8, Issue:3

    Topics: Child; Epilepsy; Humans; Infant; Intellectual Disability; Intelligence; Meningitis; Phenobarbital; P

1979

Trials

3 trials available for phenytoin and Convulsions, Febrile

ArticleYear
Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions.
    Lancet (London, England), 1981, Sep-19, Volume: 2, Issue:8247

    Topics: Age Factors; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbi

1981
Controlled and comparative trials of valproate performed in Europe and Asia.
    Epilepsia, 1984, Volume: 25 Suppl 1

    Topics: Adolescent; Adult; Asia; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Europe; Humans; P

1984
Behavioural effects of phenobarbitone and phenytoin in small children.
    Archives of disease in childhood, 1981, Volume: 56, Issue:11

    Topics: Child Behavior Disorders; Female; Hospitalization; Humans; Infant; Male; Phenobarbital; Phenytoin; S

1981

Other Studies

22 other studies available for phenytoin and Convulsions, Febrile

ArticleYear
Newer GABA derivatives for the treatment of epilepsy including febrile seizures: a bioisosteric approach.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:12

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Dru

2008
Dramatic Improvement in Seizures With Phenytoin Treatment in an Individual With Refractory Epilepsy and a SCN1B Variant.
    Pediatric neurology, 2020, Volume: 108

    Topics: Anticonvulsants; Child, Preschool; Drug Resistant Epilepsy; Electroencephalography; Epilepsy, Genera

2020
Fosphenytoin vs. continuous midazolam for pediatric febrile status epilepticus.
    Brain & development, 2018, Volume: 40, Issue:10

    Topics: Anticonvulsants; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Male; Midazolam; O

2018
Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons.
    Human molecular genetics, 2013, Nov-01, Volume: 22, Issue:21

    Topics: Action Potentials; Anticonvulsants; Cell Differentiation; Cell Line; Epilepsies, Myoclonic; Gene Exp

2013
Role of MDR1 C3435T and GABRG2 C588T gene polymorphisms in seizure occurrence and MDR1 effect on anti-epileptic drug (phenytoin) absorption.
    Genetic testing and molecular biomarkers, 2012, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding

2012
Lack of efficacy of phenytoin in children presenting with febrile status epilepticus.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:9

    Topics: Anticonvulsants; Emergency Service, Hospital; Humans; Infant; Male; Phenytoin; Retrospective Studies

2012
Lack of efficacy of phenytoin in children presenting with febrile status epilepticus.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:9

    Topics: Anticonvulsants; Humans; Male; Phenytoin; Seizures, Febrile; Status Epilepticus

2012
[FEBRILE CONVULSIONS IN CHILDREN. PROGNOSTIC STUDIES AND AN ATTEMPTED EVALUATION OF THE EFFECTS OF PROLONGED PROPHYLACTIC ANTIEPILEPSY TREATMENT. A PRELIMINARY REPORT].
    Ugeskrift for laeger, 1964, Feb-13, Volume: 126

    Topics: Child; Denmark; Epilepsy; Exanthema Subitum; Fever; Humans; Infant; Phenytoin; Prognosis; Respirator

1964
Prophylaxis of febrile convulsions.
    Lancet (London, England), 1981, Oct-24, Volume: 2, Issue:8252

    Topics: Humans; Infant; Phenobarbital; Phenytoin; Random Allocation; Seizures, Febrile

1981
Effect of hyperthermia on a thalamocortical system in the kitten and the cat: a preliminary study.
    Neurological research, 1983, Volume: 5, Issue:3

    Topics: Animals; Cats; Cerebral Cortex; Fever; Phenytoin; Seizures, Febrile; Thalamus; Valproic Acid

1983
Febrile seizures in epileptic chicks: the effects of phenobarbital, phenytoin and valproate.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1983, Volume: 10, Issue:2

    Topics: Animals; Chickens; Disease Models, Animal; Phenobarbital; Phenytoin; Reaction Time; Seizures, Febril

1983
[Pharmacotherapy of epilepsy--current problems and controversies].
    Fortschritte der Neurologie-Psychiatrie, 1983, Volume: 51, Issue:11

    Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy,

1983
Effects of anticonvulsants on hyperthermia-induced seizures in the rat pup.
    Epilepsia, 1984, Volume: 25, Issue:1

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Differential Threshold; Disease Model

1984
Monitoring of phenobarbitone and phenytoin therapy in small children by salivary samples.
    Therapeutic drug monitoring, 1981, Volume: 3, Issue:3

    Topics: Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Phenytoin; Saliva; Seizures, Febril

1981
Epilepsy.
    Neurobiology of disease, 2000, Volume: 7, Issue:5

    Topics: Animals; Anticonvulsants; Electrophysiology; Epilepsy; Humans; Mutation; Neurons; Phenytoin; Seizure

2000
[Treatment of febrile convulsions].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:1

    Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; D

2002
Epilepsy in childhood.
    The New Zealand medical journal, 1978, Nov-22, Volume: 88, Issue:624

    Topics: Anticonvulsants; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Infant; Infant,

1978
Febrile seizures and thalamocortical activity: a comparison of effects of valproate and phenytoin.
    Transactions of the American Neurological Association, 1979, Volume: 104

    Topics: Animals; Cats; Cerebral Cortex; Neural Pathways; Phenytoin; Seizures; Seizures, Febrile; Thalamus; V

1979
Anticonvulsant therapy. Approaches to some common clinical problems.
    Postgraduate medicine, 1979, Volume: 65, Issue:3

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Eth

1979
Controversies in the treatment of febrile convulsions.
    Neurology, 1979, Volume: 29, Issue:3

    Topics: Child; Epilepsy; Humans; Intelligence; Phenobarbital; Phenytoin; Prognosis; Seizures; Seizures, Febr

1979
[Interval therapy of febrile convulsions for the management of their prognosis. I. Methods and therapeutic advice for interval therapy of febrile convulsions].
    Kinderarztliche Praxis, 1976, Volume: 44, Issue:11

    Topics: Child, Preschool; Epilepsy; Humans; Infant; Periodicity; Phenobarbital; Phenytoin; Recurrence; Seizu

1976
[Convulsive crises in childhood].
    Anales espanoles de pediatria, 1985, Volume: 23, Issue:8

    Topics: Clonazepam; Crying; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Mi

1985