Page last updated: 2024-10-21

phenytoin and Congenital Limb Deformities

phenytoin has been researched along with Congenital Limb Deformities in 9 studies

Research Excerpts

ExcerptRelevanceReference
"Phenytoin is one of the most well established and most effective antiepileptic medications for the treatment of focal seizures."3.83Phenytoin toxicity in two-month-old Thai infant with CYP2C9 gene polymorphism--A case report. ( Jaroonvanichkul, V; Netbaramee, W; Phaisarn, P; Uyathanarat, T; Veeravigrom, M, 2016)
"Birth defects associated with phenytoin and phenobarbital taken during pregnancy include craniofacial and limb deformities."3.66Fetal hydantoin syndrome in triplets. A unique experiment of nature. ( Bustamante, SA; Stumpff, LC, 1978)
"A second case of severe limb malformations was observed following maternal use of haloperidol early in the first trimester of pregnancy."3.65Limb malformations following maternal use of haloperidol. ( Heggeness, L; McCullar, FW, 1975)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Veeravigrom, M1
Jaroonvanichkul, V1
Netbaramee, W1
Phaisarn, P1
Uyathanarat, T1
Holmes, LB1
Lorente, CA1
Tassinari, MS1
Keith, DA1
Fantel, AG1
Bustamante, SA1
Stumpff, LC1
Dabee, V1
Hart, AG1
Hurley, RM1
McCullar, FW1
Heggeness, L1
Reisner, SH1
Weitz, R1
Korczyn, AD1
Danielson, MK1
Danielsson, BR1
Marchner, H1
Lundin, M1
Rundqvist, E1
Reiland, S1

Reviews

1 review available for phenytoin and Congenital Limb Deformities

ArticleYear
Teratogen-induced limb defects.
    American journal of medical genetics, 2002, Oct-15, Volume: 112, Issue:3

    Topics: Chorionic Villi Sampling; Female; Humans; Limb Deformities, Congenital; Male; Misoprostol; Phenytoin

2002

Other Studies

8 other studies available for phenytoin and Congenital Limb Deformities

ArticleYear
Phenytoin toxicity in two-month-old Thai infant with CYP2C9 gene polymorphism--A case report.
    Brain & development, 2016, Volume: 38, Issue:1

    Topics: Anal Canal; Anticonvulsants; Cytochrome P-450 CYP2C9; Esophagus; Heart Defects, Congenital; Humans;

2016
The effects of phenytoin on rat development: an animal model system for fetal hydantoin syndrome.
    Teratology, 1981, Volume: 24, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Female; Growth Disorders; Humans; Inte

1981
Vasoactive teratogens and digital blood flow.
    Teratology, 1999, Volume: 60, Issue:3

    Topics: Adolescent; Adult; Animals; Anticonvulsants; Female; Fingers; Humans; Limb Deformities, Congenital;

1999
Fetal hydantoin syndrome in triplets. A unique experiment of nature.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:10

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Epilepsy; Face; Female; Growth Disorder

1978
Teratogenic effects of diphenylhydantoin.
    Canadian Medical Association journal, 1975, Jan-11, Volume: 112, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Breast; Epilepsy; Face; Female; Hernia, Inguinal; Hip Dislocatio

1975
Limb malformations following maternal use of haloperidol.
    JAMA, 1975, Jan-06, Volume: 231, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Drug Therapy, Combination; Female; Fetus; Halo

1975
[Teratogenic effects of anticonvulsants].
    Harefuah, 1976, Feb-15, Volume: 90, Issue:4

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Humans; Infant, Newborn; Limb Deformities, Congenital;

1976
Histopathological and hemodynamic studies supporting hypoxia and vascular disruption as explanation to phenytoin teratogenicity.
    Teratology, 1992, Volume: 46, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Facial Bones; Female; Fetal Hypoxia; Gestational Age; Heart Ra

1992