phenytoin has been researched along with Coma in 36 studies
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a double-blind trial to determine whether a single intramuscular injection of fosphenytoin prevents seizures and neurologic sequelae in children with acute coma." | 9.17 | Fosphenytoin for seizure prevention in childhood coma in Africa: a randomized clinical trial. ( Chengo, EM; Crawley, J; Fegan, G; Gwer, SA; Idro, RI; Kihara, MN; Kirkham, FJ; Kivaya, E; Mpoya, A; Muchohi, SN; Newton, CR; Ogutu, BR, 2013) |
| "Valproic acid induced coma is presented in an adult patient without a history of metabolic disease." | 7.68 | Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma. ( Colombo, JP; Straver, JS; van der Vijver, JC; van Woerkom, TC; Verbiest, HB, 1992) |
| "He also had visual hallucinations and temporary high blood pressure." | 5.37 | Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report. ( Kato, S; Kobayashi, T; Saito, N; Shioda, K; Suda, S, 2011) |
| "Status epilepticus is one of the most frequent neurological emergencies in the intensive care unit." | 5.29 | Propofol in the management of refractory status epilepticus: a case report. ( Borgeat, A; Jallon, P; Suter, PM; Wilder-Smith, OH, 1994) |
| "We conducted a double-blind trial to determine whether a single intramuscular injection of fosphenytoin prevents seizures and neurologic sequelae in children with acute coma." | 5.17 | Fosphenytoin for seizure prevention in childhood coma in Africa: a randomized clinical trial. ( Chengo, EM; Crawley, J; Fegan, G; Gwer, SA; Idro, RI; Kihara, MN; Kirkham, FJ; Kivaya, E; Mpoya, A; Muchohi, SN; Newton, CR; Ogutu, BR, 2013) |
| "To report a case of hyperammonemia without hepatic dysfunction as a possible cause of lethargy, stupor, and coma in a woman after valproic acid (VPA) administration, and discuss the possible different mechanisms of ammonia elevation and coma." | 4.78 | Valproate-induced coma: case report and literature review. ( Clavería, LE; Coria, F; Duarte, J; Fernandez, E; Macias, S, 1993) |
| "Valproic acid induced coma is presented in an adult patient without a history of metabolic disease." | 3.68 | Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma. ( Colombo, JP; Straver, JS; van der Vijver, JC; van Woerkom, TC; Verbiest, HB, 1992) |
| "Total (bound + unbound) and unbound phenytoin serum concentrations were measured in ten male comatose head trauma patients and ten male epileptic patients." | 3.66 | Importance of unbound phenytoin serum levels in head trauma patients. ( Bauer, LA; Brennan, C; Dellinger, EP; Edwards, WA; Raisys, VA, 1983) |
| "Total external ophthalmoplegia was observed in five patients consequent to the oral or intravenous administration of phenytoin." | 3.65 | Phenytoin-induced ophthalmoplegia. ( Davidoff, RA; Schwartzman, RJ; Spector, RH, 1976) |
| "ECTR is suggested if prolonged coma is present or expected (graded 2D) and it would be reasonable if prolonged incapacitating ataxia is present or expected (graded 3D)." | 2.53 | Extracorporeal Treatment in Phenytoin Poisoning: Systematic Review and Recommendations from the EXTRIP (Extracorporeal Treatments in Poisoning) Workgroup. ( Anseeuw, K; Burdmann, EA; Ghannoum, M; Gosselin, S; Hoffman, RS; Lavergne, V; Mowry, JB; Nolin, TD, 2016) |
| "Seizures are commonly encountered in patients who do not have epilepsy." | 2.40 | Medical causes of seizures. ( Delanty, N; French, JA; Vaughan, CJ, 1998) |
| "He also had visual hallucinations and temporary high blood pressure." | 1.37 | Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report. ( Kato, S; Kobayashi, T; Saito, N; Shioda, K; Suda, S, 2011) |
| "A 75-year-old man suffered a cardiac arrest and severe anoxic encephalopathy." | 1.30 | Periodic complexes, absence-like status and suppression-burst pattern in coma following cardiorespiratory arrest. ( Chemmale, J; Devrajan, VN; Ganji, SS; McDonald, L; Palliyath, S, 1997) |
| "Status epilepticus is one of the most frequent neurological emergencies in the intensive care unit." | 1.29 | Propofol in the management of refractory status epilepticus: a case report. ( Borgeat, A; Jallon, P; Suter, PM; Wilder-Smith, OH, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (66.67) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (19.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gwer, SA | 1 |
| Idro, RI | 1 |
| Fegan, G | 1 |
| Chengo, EM | 1 |
| Mpoya, A | 1 |
| Kivaya, E | 1 |
| Crawley, J | 1 |
| Muchohi, SN | 1 |
| Kihara, MN | 1 |
| Ogutu, BR | 1 |
| Kirkham, FJ | 1 |
| Newton, CR | 1 |
| Anseeuw, K | 1 |
| Mowry, JB | 1 |
| Burdmann, EA | 1 |
| Ghannoum, M | 1 |
| Hoffman, RS | 1 |
| Gosselin, S | 1 |
| Lavergne, V | 1 |
| Nolin, TD | 1 |
| Nelsen, JL | 1 |
| Lapoint, J | 1 |
| Hodgman, MJ | 1 |
| Aldous, KM | 1 |
| Suresh Chandran, CJ | 1 |
| Saddiq, MH | 1 |
| Joji, P | 1 |
| Unni, M | 1 |
| Maconochie, I | 1 |
| Ross, M | 1 |
| Bischoff, K | 1 |
| Jaeger, R | 1 |
| Ebel, JG | 1 |
| Kobayashi, T | 1 |
| Saito, N | 1 |
| Suda, S | 1 |
| Shioda, K | 1 |
| Kato, S | 1 |
| FROMMEL, E | 1 |
| RADOUCO-THOMAS, C | 1 |
| CELESIA, GG | 1 |
| ANDERMANN, F | 1 |
| LIEBERMAN, A | 1 |
| RIZZUTO, VJ | 1 |
| INGLESBY, TV | 1 |
| GRACE, WJ | 1 |
| Perez del Cerro, M | 1 |
| Snider, RS | 1 |
| Levy, RS | 1 |
| Jankovic, J | 1 |
| Sabato, AF | 1 |
| Pala, F | 1 |
| Sammartino, M | 1 |
| Barbi, S | 1 |
| Beccia, F | 1 |
| Lüscher, TF | 1 |
| Siegenthaler-Zuber, G | 1 |
| Kuhlmann, U | 1 |
| Bauer, LA | 1 |
| Edwards, WA | 1 |
| Dellinger, EP | 1 |
| Raisys, VA | 1 |
| Brennan, C | 1 |
| Albertson, TE | 1 |
| Fisher, CJ | 1 |
| Shragg, TA | 1 |
| Baselt, RC | 1 |
| Borgeat, A | 1 |
| Wilder-Smith, OH | 1 |
| Jallon, P | 1 |
| Suter, PM | 1 |
| Duarte, J | 1 |
| Macias, S | 1 |
| Coria, F | 1 |
| Fernandez, E | 1 |
| Clavería, LE | 1 |
| Ganji, SS | 1 |
| Palliyath, S | 1 |
| Chemmale, J | 1 |
| Devrajan, VN | 1 |
| McDonald, L | 1 |
| Delanty, N | 1 |
| Vaughan, CJ | 1 |
| French, JA | 1 |
| Besser, R | 1 |
| Schuster, CJ | 1 |
| Spector, RH | 1 |
| Davidoff, RA | 1 |
| Schwartzman, RJ | 1 |
| Verbiest, HB | 1 |
| Straver, JS | 1 |
| Colombo, JP | 1 |
| van der Vijver, JC | 1 |
| van Woerkom, TC | 1 |
| Fahn, S | 1 |
| Goto, K | 1 |
| Suekawa, M | 1 |
| Aburada, M | 1 |
| Hosoya, E | 1 |
| Aitkenhead, A | 1 |
| Lehtovaara, R | 1 |
| Karch, SB | 1 |
| Moss-Herjanic, B | 1 |
| Madden, JS | 1 |
| Jones, D | 1 |
| Frisch, EP | 1 |
| Viukari, NM | 1 |
| Aho, K | 1 |
| Riddell, D | 1 |
| Leonard, BE | 1 |
| Sampson, D | 1 |
| Harasymiv, I | 1 |
| Hensley, WJ | 1 |
| Tenckhoff, H | 1 |
| Sherrard, DJ | 1 |
| Hickman, RO | 1 |
| Ladda, RL | 1 |
| Goldberg, EM | 1 |
| Sanbar, SS | 1 |
5 reviews available for phenytoin and Coma
| Article | Year |
|---|---|
Extracorporeal Treatment in Phenytoin Poisoning: Systematic Review and Recommendations from the EXTRIP (Extracorporeal Treatments in Poisoning) Workgroup.
Topics: Coma; Education; Humans; Phenytoin; Practice Guidelines as Topic; Renal Dialysis; Treatment Outcome | 2016 |
Head injury (moderate to severe).
Topics: Acute Disease; Anticonvulsants; Brain Injuries; Brain Ischemia; Coma; Craniocerebral Trauma; Glasgow | 2010 |
Valproate-induced coma: case report and literature review.
Topics: Ammonia; Coma; Epilepsy, Complex Partial; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Val | 1993 |
Medical causes of seizures.
Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Broncho | 1998 |
Posthypoxic action myoclonus: literature review update.
Topics: Adult; Clonazepam; Coma; Electroencephalography; Female; Functional Laterality; Heart Arrest; Humans | 1986 |
1 trial available for phenytoin and Coma
| Article | Year |
|---|---|
Fosphenytoin for seizure prevention in childhood coma in Africa: a randomized clinical trial.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Coma; Double-Blind Method; Electroencephalogra | 2013 |
30 other studies available for phenytoin and Coma
| Article | Year |
|---|---|
Seizure and coma following Kratom (Mitragynina speciosa Korth) exposure.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Coma; Glasgow Coma Scale; Humans; Intubation, | 2010 |
Hemi brain demyelination--a variant of acute disseminated encephalomyelitis.
Topics: Acyclovir; Anti-Inflammatory Agents; Anticonvulsants; Antiviral Agents; Brain; Child; Coma; Encephal | 2010 |
An unusual case of relay pentobarbital toxicosis in a dog.
Topics: Adipose Tissue; Animals; Anticonvulsants; Coma; Dog Diseases; Dogs; Female; Gas Chromatography-Mass | 2011 |
Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report.
Topics: Anticonvulsants; Bipolar Disorder; Coma; Diazepam; Drug Overdose; Drug Resistance; Hallucinations; H | 2011 |
[Effects of phenobarbital, acylureas and diphenylhydantoin on coma during electric epileptic crisis in guinea pig. II..].
Topics: Anticonvulsants; Barbiturates; Coma; Electricity; Epilepsy; Guinea Pigs; Phenobarbital; Phenytoin; S | 1953 |
SOME OBSERVATIONS ON THE ELECTROGRAPHIC CORRELATES OF THE DECEREBRATE ATTACK.
Topics: Child; Coma; Decerebrate State; Electroencephalography; Epilepsy; Humans; Hypoxia, Brain; Infusions, | 1964 |
INTERMITTENT CEREBRAL INSUFFICIENCY. REPORT OF CASE WITH COMPLETE CLINICAL RECOVERY BETWEEN EPISODES OF COMA.
Topics: Arteriosclerosis; Autonomic Nerve Block; Carotid Artery Thrombosis; Cerebral Angiography; Cerebral I | 1965 |
PROBENECID (BENEMID) INTOXICATION WITH STATUS EPILEPTICUS.
Topics: Coma; Drug Therapy; Epilepsy; Gout; Phenobarbital; Phenytoin; Poisoning; Probenecid; Status Epilepti | 1965 |
Studies on Dilantin intoxication. I. Ultrastructural analogies with the lipoidoses.
Topics: Animals; Ataxia; Cerebellar Cortex; Coma; Cytoplasmic Granules; Lipidoses; Male; Microscopy, Electro | 1967 |
Placebo-induced conversion reaction: a neurobehavioral and EEG study of hysterical aphasia, seizure, and coma.
Topics: Adult; Aphasia; Coma; Conversion Disorder; Female; Humans; Phenytoin; Seizures; Set, Psychology | 1983 |
The brain amino acid pattern in experimental coma due to phenytoin in guinea pigs.
Topics: Amino Acids; Animals; Brain; Chromatography, Ion Exchange; Coma; Guinea Pigs; Phenytoin | 1984 |
Severe hypernatremic coma due to diphenylhydantoin intoxication.
Topics: Adult; Coma; Epilepsy, Tonic-Clonic; Female; Humans; Hypernatremia; Phenytoin | 1983 |
Importance of unbound phenytoin serum levels in head trauma patients.
Topics: Adult; Coma; Craniocerebral Trauma; Epilepsy, Post-Traumatic; Humans; Immunoenzyme Techniques; Male; | 1983 |
A prolonged severe intoxication after ingestion of phenytoin and phenobarbital.
Topics: Adult; Coma; Confusion; Female; Gastric Lavage; Humans; Nystagmus, Pathologic; Phenobarbital; Phenyt | 1981 |
Propofol in the management of refractory status epilepticus: a case report.
Topics: Clonazepam; Coma; Drug Therapy, Combination; Electroencephalography; Glasgow Coma Scale; Humans; Inf | 1994 |
Periodic complexes, absence-like status and suppression-burst pattern in coma following cardiorespiratory arrest.
Topics: Aged; Anticonvulsants; Brain; Coma; Diazepam; Electroencephalography; Epilepsy, Absence; Heart Arres | 1997 |
[Influence of diphenylhydantoine on delta sharp-waves in coma. A clinical contribution (author's transl)].
Topics: Coma; Delta Rhythm; Humans; Male; Middle Aged; Narcotics; Phenytoin; Poisoning | 1979 |
Phenytoin-induced ophthalmoplegia.
Topics: Adolescent; Adult; Coma; Epilepsy, Tonic-Clonic; Humans; Male; Middle Aged; Ophthalmoplegia; Phenyto | 1976 |
Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Atrophy; Carbamoyl-Phosphate Synthase (Ammonia | 1992 |
[Pharmacological study of TJ-8007 (Tsumura-Zokumeito) (I): Protective effects of TJ-8007 against anoxic brain damage].
Topics: Animals; Brain Damage, Chronic; Coma; Drugs, Chinese Herbal; Hypoxia, Brain; Male; Medicine, Chinese | 1987 |
Cerebral protection.
Topics: Adrenal Cortex Hormones; Barbiturates; Blood Glucose; Brain Edema; Brain Ischemia; Calcium Channel B | 1986 |
[Therapy in traumatic epilepsy].
Topics: Adult; Barbiturates; Bromides; Carbamazepine; Coma; Disabled Persons; Drug Resistance; Epilepsy, Pos | 1971 |
Methsuximide overdose. Delayed onset of profound coma.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Central Nervous System; Coma; Drug Synergism; Ele | 1973 |
Prolonged unconsciousness following electroconvulsive therapy.
Topics: Adult; Aged; Coma; Craniocerebral Trauma; Depression; Electroconvulsive Therapy; Epilepsies, Partial | 1967 |
Chlormethiazole and trifluoperazine in alcohol withdrawal.
Topics: Alcoholism; Chlormethiazole; Coma; Depression; Feeding and Eating Disorders; Female; Headache; Human | 1969 |
Digoxin-phenytoin interaction.
Topics: Ataxia; Cerebellar Diseases; Coma; Digoxin; Humans; Male; Middle Aged; Phenytoin | 1970 |
Some properties of a coma producing material obtained from mammalian brain.
Topics: Amylases; Animals; Blood Pressure; Brain Chemistry; Carbamazepine; Cats; Cerebral Cortex; Chromatogr | 1970 |
Gas chromatographic assay of underivatized 5,5-diphenylhydantoin (dilantin) in plasma extracts.
Topics: Carbamazepine; Chloroform; Chromatography, Gas; Coma; Epilepsy; Humans; Hydrogen-Ion Concentration; | 1971 |
Acute diphenylhydantoin intoxication.
Topics: Child, Preschool; Coma; Decerebrate State; Humans; Male; Peritoneal Dialysis; Phenytoin | 1968 |
Hyperglycemic, nonketotic coma following administration of Dilantin (Diphenylhydantoin).
Topics: Animals; Blood Glucose; Blood Pressure; Coma; Dogs; Fatty Acids, Nonesterified; Humans; Hyperglycemi | 1969 |