Page last updated: 2024-10-21

phenytoin and Collagen Diseases

phenytoin has been researched along with Collagen Diseases in 5 studies

Collagen Diseases: Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that collagen was equivalent to connective tissue, but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term collagen diseases now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)

Research Excerpts

ExcerptRelevanceReference
"Phenytoin, given to a cat in proportions therapeutic for man (5 to 8 mg/kg), induced severe dermal atrophy with excessive fragility of the skin following daily oral administration for 3 weeks."7.66Reversible dermal atrophy in a cat treated with phenytoin. ( Barthold, SW; Kaplan, BJ; Schwartz, A, 1980)
"Phenytoin has a wide range of pharmacologic effects other than its anticonvulsant activity."3.75Phenytoin revisited. ( Finkel, MJ, 1984)
"Phenytoin, given to a cat in proportions therapeutic for man (5 to 8 mg/kg), induced severe dermal atrophy with excessive fragility of the skin following daily oral administration for 3 weeks."3.66Reversible dermal atrophy in a cat treated with phenytoin. ( Barthold, SW; Kaplan, BJ; Schwartz, A, 1980)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaeser, HE1
Finkel, MJ1
Barthold, SW1
Kaplan, BJ1
Schwartz, A1
Podymov, VK1
Gladkikh, SP1
Piruzian, LA1
Dano, P1

Reviews

2 reviews available for phenytoin and Collagen Diseases

ArticleYear
Drug-induced myasthenic syndromes.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 100

    Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Autoimmune Diseas

1984
Phenytoin revisited.
    Clinical therapeutics, 1984, Volume: 6, Issue:5

    Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Cerebrovascular Disorders; Clinical Trials as Topic;

1984

Trials

1 trial available for phenytoin and Collagen Diseases

ArticleYear
Phenytoin revisited.
    Clinical therapeutics, 1984, Volume: 6, Issue:5

    Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Cerebrovascular Disorders; Clinical Trials as Topic;

1984

Other Studies

3 other studies available for phenytoin and Collagen Diseases

ArticleYear
Reversible dermal atrophy in a cat treated with phenytoin.
    Veterinary pathology, 1980, Volume: 17, Issue:4

    Topics: Administration, Oral; Animals; Atrophy; Cat Diseases; Cats; Collagen Diseases; Male; Phenytoin; Skin

1980
[Molecular aspects of connective tissue fibrillogenesis disorders caused by drug ligands].
    Doklady Akademii nauk SSSR, 1979, Volume: 246, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Collagen; Collagen Diseases; Elastin; Humans; Hydralazine; I

1979
Connective tissue disease following anti-epileptic therapy.
    Epilepsia, 1969, Volume: 10, Issue:4

    Topics: Adult; Anticonvulsants; Child; Collagen Diseases; Electroencephalography; Epilepsy, Absence; Epileps

1969