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phenytoin and Cockayne-Touraine Disease

phenytoin has been researched along with Cockayne-Touraine Disease in 3 studies

Research Excerpts

ExcerptRelevanceReference
"Recessive dystrophic epidermolysis bullosa is an uncommon, severely disabling, heritable disorder characterized by abnormal fragility of the skin."2.67Lack of efficacy of phenytoin in recessive dystrophic epidermolysis bullosa. Epidermolysis Bullosa Study Group. ( Caldwell-Brown, D; Carter, DM; Lin, AN; Stern, RS, 1992)
"Recessive dystrophic epidermolysis bullosa (RDEB) is a group of genetic disorders in which blistering occurs below the basement membrane, in many cases resulting in extensive scar formation, contractures and mitten deformities."1.30Phenytoin reduces the contraction of recessive dystrophic epidermolysis bullosa fibroblast populated collagen gels. ( Adams, TS; Brown, RA; Eastwood, M; Rubio, G; Talas, G, 1997)
"The phenytoin-treated group showed marked decrease in blister count, increase in trauma tolerance, a rise in hemoglobin level, and considerable weight gain."1.28Recessive dystrophic epidermolysis bullosa treated with phenytoin. ( Abahussein, AA; al-Zayir, AA; Mostafa, WZ; Okoro, AN, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Talas, G1
Adams, TS1
Eastwood, M1
Rubio, G1
Brown, RA1
Abahussein, AA1
al-Zayir, AA1
Mostafa, WZ1
Okoro, AN1
Caldwell-Brown, D1
Stern, RS1
Lin, AN1
Carter, DM1

Trials

1 trial available for phenytoin and Cockayne-Touraine Disease

ArticleYear
Lack of efficacy of phenytoin in recessive dystrophic epidermolysis bullosa. Epidermolysis Bullosa Study Group.
    The New England journal of medicine, 1992, Jul-16, Volume: 327, Issue:3

    Topics: Adolescent; Child; Double-Blind Method; Drug Administration Schedule; Epidermolysis Bullosa Dystroph

1992

Other Studies

2 other studies available for phenytoin and Cockayne-Touraine Disease

ArticleYear
Phenytoin reduces the contraction of recessive dystrophic epidermolysis bullosa fibroblast populated collagen gels.
    The international journal of biochemistry & cell biology, 1997, Volume: 29, Issue:1

    Topics: Biomechanical Phenomena; Cell Line; Collagen; Contracture; Epidermolysis Bullosa Dystrophica; Fibrob

1997
Recessive dystrophic epidermolysis bullosa treated with phenytoin.
    International journal of dermatology, 1992, Volume: 31, Issue:10

    Topics: Administration, Oral; Epidermolysis Bullosa Dystrophica; Female; Genes, Recessive; Hemoglobins; Huma

1992