Page last updated: 2024-10-21

phenytoin and Closed Head Injuries

phenytoin has been researched along with Closed Head Injuries in 5 studies

Research Excerpts

ExcerptRelevanceReference
"We determine the efficacy of prophylactic phenytoin in preventing early posttraumatic seizures in children with moderate to severe blunt head injury."9.11A randomized, double-blinded, placebo-controlled trial of phenytoin for the prevention of early posttraumatic seizures in children with moderate to severe blunt head injury. ( Baren, JM; Huff, KR; Inkelis, SH; Lewis, RJ; McBride, DQ; Okada, PJ; Palchak, MJ; Panacek, EA; Sokolove, PE; Young, KD, 2004)
"We determine the efficacy of prophylactic phenytoin in preventing early posttraumatic seizures in children with moderate to severe blunt head injury."5.11A randomized, double-blinded, placebo-controlled trial of phenytoin for the prevention of early posttraumatic seizures in children with moderate to severe blunt head injury. ( Baren, JM; Huff, KR; Inkelis, SH; Lewis, RJ; McBride, DQ; Okada, PJ; Palchak, MJ; Panacek, EA; Sokolove, PE; Young, KD, 2004)
"The purposes of this study were to examine the current Brain Trauma Foundation recommendation for antiseizure prophylaxis with phenytoin during the first 7 days after traumatic brain injury (TBI) in preventing seizures and to determine if this medication affects functional recovery at discharge."3.80More harm than good: antiseizure prophylaxis after traumatic brain injury does not decrease seizure rates but may inhibit functional recovery. ( Bhullar, IS; Frykberg, ER; Johnson, D; Kerwin, AJ; Paul, JP; Tepas, JJ, 2014)
" The overall conclusions from 2 recent studies in aneurysmal subarachnoid hemorrhage are that 1) many patients receive AEDs but should not; 2) long-term use is associated with worse outcome; and 3) short-term use is safer."2.44Antiepileptic drugs in aneurysmal subarachnoid hemorrhage. ( Wijdicks, EF; Zubkov, AY, 2008)
"Intracranial sinus thrombosis (1ST) after closed head injury is an uncommon but potentially serious complication."1.39[Cerebral vein thrombosis secondary to closed head injury. Report of one case]. ( Godoy F, J; Mellado T, P; Suárez H, F, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhullar, IS1
Johnson, D1
Paul, JP1
Kerwin, AJ1
Tepas, JJ1
Frykberg, ER1
Suárez H, F1
Mellado T, P1
Godoy F, J1
Zubkov, AY1
Wijdicks, EF1
Young, KD1
Okada, PJ1
Sokolove, PE1
Palchak, MJ1
Panacek, EA1
Baren, JM1
Huff, KR1
McBride, DQ1
Inkelis, SH1
Lewis, RJ1
Fish, SS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Short-Term Anti-Seizure Prophylaxis After Traumatic Brain Injury Decrease Seizure Rates?[NCT03054285]Phase 42,300 participants (Anticipated)Interventional2017-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phenytoin and Closed Head Injuries

ArticleYear
Antiepileptic drugs in aneurysmal subarachnoid hemorrhage.
    Reviews in neurological diseases, 2008,Fall, Volume: 5, Issue:4

    Topics: Animals; Anticonvulsants; Electroencephalography; Head Injuries, Closed; Humans; Levetiracetam; Neur

2008

Trials

1 trial available for phenytoin and Closed Head Injuries

ArticleYear
A randomized, double-blinded, placebo-controlled trial of phenytoin for the prevention of early posttraumatic seizures in children with moderate to severe blunt head injury.
    Annals of emergency medicine, 2004, Volume: 43, Issue:4

    Topics: Adolescent; Anticonvulsants; Barbiturates; Bayes Theorem; Benzodiazepines; Child; Child, Preschool;

2004

Other Studies

3 other studies available for phenytoin and Closed Head Injuries

ArticleYear
More harm than good: antiseizure prophylaxis after traumatic brain injury does not decrease seizure rates but may inhibit functional recovery.
    The journal of trauma and acute care surgery, 2014, Volume: 76, Issue:1

    Topics: Adult; Anticonvulsants; Brain Injuries; Female; Glasgow Coma Scale; Head Injuries, Closed; Humans; M

2014
[Cerebral vein thrombosis secondary to closed head injury. Report of one case].
    Revista medica de Chile, 2013, Volume: 141, Issue:12

    Topics: Adult; Anticoagulants; Anticonvulsants; Cerebral Veins; Head Injuries, Closed; Heparin; Humans; Magn

2013
Informed consent: time for a national dialogue?
    Annals of emergency medicine, 2004, Volume: 43, Issue:4

    Topics: Anticonvulsants; Child; Emergency Medicine; Head Injuries, Closed; Humans; Informed Consent; Parenta

2004