phenytoin has been researched along with Chronic Disease in 81 studies
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare topical diphenylhydantoin (phenytoin) with Edinburgh University solution of lime (EUSOL) in terms of rate of ulcer healing, analgesic and antibacterial properties in non-malignant chronic leg ulcers." | 9.10 | Topical phenytoin versus EUSOL in the treatment of non-malignant chronic leg ulcers. ( Carneiro, PM; Nyawawa, ET, 2003) |
| "In view of the reports that phenytoin and honey are useful in the healing of wounds, a comparison of their topical use in the treatment of chronic leg ulcers was carried out." | 9.09 | A comparison of topical honey and phenytoin in the treatment of chronic leg ulcers. ( Olabanji, JK; Oluwatosin, OA; Oluwatosin, OM; Onyechi, HU; Tijani, LA, 2000) |
| "Women with a singleton pregnancy in vertex presentation between 32 and 42 weeks' gestation who required induction of labor for either preeclampsia, preeclampsia superimposed on chronic hypertension, or transient hypertension were randomized to receive either magnesium sulfate or phenytoin (Dilantin) for seizure prophylaxis." | 9.08 | Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension? ( Atkinson, MW; Guinn, D; Hauth, JC; Owen, J, 1995) |
| "The wound healing effects of topical phenytoin powder were compared with those of normal saline in a controlled in-patient study of 100 patients with 110 trophic leprosy ulcers of varying chronicity, over a 4-week study period." | 9.07 | Comparison of topical phenytoin with normal saline in the treatment of chronic trophic ulcers in leprosy. ( Bansal, NK, 1993) |
| "The purpose of this study was to assess the possible role of the (R)- and (S)- enantiomers of the phenytoin metabolite p-HPPH in the pathogenesis of gingival hyperplasia (GH)." | 7.69 | Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study. ( Goto, W; Higuchi, S; Hirata, K; Ieiri, I; Imayama, S; Ohtsubo, K; Ohyama, Y; Toshitani, A; Yamada, H, 1995) |
| " The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene." | 7.68 | Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990) |
| "Reversible chronic cerebellar ataxia followed phenytoin treatment in two epileptic women." | 7.67 | Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought. ( Attig, E; Botez, MI; Gravel, J; Vézina, JL, 1985) |
| "Phenobarbital and MK-801 were superior to phenytoin in suppressing SE and in preventing chronic epilepsy." | 5.31 | Phenobarbital and MK-801, but not phenytoin, improve the long-term outcome of status epilepticus. ( Bertram, EH; Prasad, A; Williamson, JM, 2002) |
| "AVO cream significantly accelerates biological healing of chronic wounds and helps to reduce pain severity with a higher efficacy compared with phenytoin cream." | 5.20 | Comparative trial of Aloe vera/olive oil combination cream versus phenytoin cream in the treatment of chronic wounds. ( Beiraghdar, F; Izadi, M; Jonaidi-Jafari, N; Panahi, Y; Rezaee, R; Sahebkar, A; Sayyadi, N; Zamani, A, 2015) |
| "To compare topical diphenylhydantoin (phenytoin) with Edinburgh University solution of lime (EUSOL) in terms of rate of ulcer healing, analgesic and antibacterial properties in non-malignant chronic leg ulcers." | 5.10 | Topical phenytoin versus EUSOL in the treatment of non-malignant chronic leg ulcers. ( Carneiro, PM; Nyawawa, ET, 2003) |
| "In view of the reports that phenytoin and honey are useful in the healing of wounds, a comparison of their topical use in the treatment of chronic leg ulcers was carried out." | 5.09 | A comparison of topical honey and phenytoin in the treatment of chronic leg ulcers. ( Olabanji, JK; Oluwatosin, OA; Oluwatosin, OM; Onyechi, HU; Tijani, LA, 2000) |
| "Women with a singleton pregnancy in vertex presentation between 32 and 42 weeks' gestation who required induction of labor for either preeclampsia, preeclampsia superimposed on chronic hypertension, or transient hypertension were randomized to receive either magnesium sulfate or phenytoin (Dilantin) for seizure prophylaxis." | 5.08 | Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension? ( Atkinson, MW; Guinn, D; Hauth, JC; Owen, J, 1995) |
| "The wound healing effects of topical phenytoin powder were compared with those of normal saline in a controlled in-patient study of 100 patients with 110 trophic leprosy ulcers of varying chronicity, over a 4-week study period." | 5.07 | Comparison of topical phenytoin with normal saline in the treatment of chronic trophic ulcers in leprosy. ( Bansal, NK, 1993) |
| "Since anticonvulsants have been used for treating neuralgias, an interest has arisen to experimentally test vigabatrin for its gabaergic mechanism of action." | 3.70 | Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain. ( Alves, ND; de Carvalho, AM; de Castro-Costa, CM; Santos, FJ; Silveira, DG, 1999) |
| "The purpose of this study was to assess the possible role of the (R)- and (S)- enantiomers of the phenytoin metabolite p-HPPH in the pathogenesis of gingival hyperplasia (GH)." | 3.69 | Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study. ( Goto, W; Higuchi, S; Hirata, K; Ieiri, I; Imayama, S; Ohtsubo, K; Ohyama, Y; Toshitani, A; Yamada, H, 1995) |
| "We report the case of a young man suffering from epilepsy who developed chronic calcified pancreatitis after ten years of therapy with the anticonvulsant drugs carbamazepine and phenytoin." | 3.68 | Anticonvulsant-induced chronic pancreatitis. A case report. ( Billi, P; Broccoli, PL; Fontana, G; Melandri, R; Pezzilli, R, 1992) |
| " The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene." | 3.68 | Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990) |
| "Reversible chronic cerebellar ataxia followed phenytoin treatment in two epileptic women." | 3.67 | Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought. ( Attig, E; Botez, MI; Gravel, J; Vézina, JL, 1985) |
| "Focal electrographic seizures in this model are resistant to several major antiepileptic drugs." | 1.42 | The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy. ( Bankstahl, M; Klein, S; Löscher, W; Römermann, K; Twele, F, 2015) |
| "Zinc oxide paste per se was not effective, but its role as a vehicle was an asset." | 1.40 | Trophic skin ulceration in leprosy: evaluation of the efficacy of topical phenytoin sodium zinc oxide paste. ( Kaviarasan, PK; Prasad, PV; Rajan, D; Sehgal, VN, 2014) |
| "Carbamazepine was the most common prescribed drug (76." | 1.38 | Trigeminal neuralgia: a retrospective study of 188 Thai cases. ( Aneksuk, V; Jainkittivong, A; Langlais, RP, 2012) |
| "Epileptic seizures drive expression of the blood-brain barrier efflux transporter P-glycoprotein via a glutamate/cyclooxygenase-2 mediated signalling pathway." | 1.36 | COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats. ( Aronica, E; Edelbroek, PM; Gorter, JA; Holtman, L; Pekcec, A; Potschka, H; Schlichtiger, J; van Vliet, EA; Zibell, G, 2010) |
| "We have observed acute dystonias in the absence of antipsychotic treatment and in the context of seizure activity (or paroxysmal dyskinetic activity)." | 1.33 | High vulnerability to acute dystonic reactions: a case of antipsychotic exposure and uncontrolled seizure activity. ( Botts, SR; Coffey, GL; de Leon, J, 2005) |
| "Phenobarbital and MK-801 were superior to phenytoin in suppressing SE and in preventing chronic epilepsy." | 1.31 | Phenobarbital and MK-801, but not phenytoin, improve the long-term outcome of status epilepticus. ( Bertram, EH; Prasad, A; Williamson, JM, 2002) |
| "Primary trigeminal neuralgia (tic douloureux) is characterized by severe paroxysms of pain often initiated by stimuli applied to trigger zones." | 1.27 | Benign chronic orofacial pain. Clinical criteria and therapeutic approaches. ( Dworkin, SF, 1983) |
| "Fifty-nine patients with chronic generalized tonic-clonic or partial seizures refractory to the maximally tolerated daily dosage of single-drug therapy with carbamazepine, phenytoin, phenobarbital, or primidone subsequently received single-drug therapy with another one of these primary anticonvulsant drugs." | 1.27 | Alternative single anticonvulsant drug therapy for refractory epilepsy. ( Richter, K; Schmidt, D, 1986) |
| "The effect of chronic administration of diphenylhydantoin on the fine structures of the rat cerebellum was ultrastructurally investigated." | 1.26 | Neurobiological studies of experimental diphenylhydantoin intoxication. - I. Electron microscopic investigations of the rat cerebellum with chronic diphenylhydantoin intoxication. ( Takeichi, M, 1981) |
| "Phenytoin dosage was increased to study the effect on the frequency of seizures and the serum concentrations of phenytoin and phenobarbitone." | 1.26 | Therapeutic and pharmacokinetic effects of increasing phenytoin in chronic epileptics on multiple drug therapy. ( Johnson, RH; Lambie, DG; Nanda, RN; Shakir, RA, 1976) |
| " (3) Use of well-standardized, yet simplified, mental performance tests in combination with changes in the dosage of medication can help in reaching a compromise between acceptable seizure control and avoidance of excessive slowing of mental activity." | 1.25 | Effects of different dosages of anticonvulsant drugs on mental performance in patients with chronic epilepsy. ( Dekaban, AS; Lehman, EJ, 1975) |
| " Unit dose packaging is used because the oral solid dosage forms (including placebos) are made to look alike." | 1.25 | Drug use and distribution in a pain rehabilitation center. ( Beckner, TF; Idsvoog, P, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (60.49) | 18.7374 |
| 1990's | 12 (14.81) | 18.2507 |
| 2000's | 12 (14.81) | 29.6817 |
| 2010's | 8 (9.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sehgal, VN | 1 |
| Prasad, PV | 1 |
| Kaviarasan, PK | 1 |
| Rajan, D | 1 |
| Twele, F | 1 |
| Bankstahl, M | 1 |
| Klein, S | 1 |
| Römermann, K | 1 |
| Löscher, W | 1 |
| Panahi, Y | 1 |
| Izadi, M | 1 |
| Sayyadi, N | 1 |
| Rezaee, R | 1 |
| Jonaidi-Jafari, N | 1 |
| Beiraghdar, F | 1 |
| Zamani, A | 1 |
| Sahebkar, A | 1 |
| Fang, Z | 1 |
| Chen, S | 1 |
| Qin, J | 1 |
| Chen, B | 1 |
| Ni, G | 1 |
| Chen, Z | 1 |
| Zhou, J | 1 |
| Li, Z | 1 |
| Ning, Y | 1 |
| Wu, C | 1 |
| Zhou, L | 1 |
| van Vliet, EA | 3 |
| Zibell, G | 1 |
| Pekcec, A | 1 |
| Schlichtiger, J | 1 |
| Edelbroek, PM | 3 |
| Holtman, L | 1 |
| Aronica, E | 2 |
| Gorter, JA | 3 |
| Potschka, H | 1 |
| Hokkam, E | 1 |
| El-Labban, G | 1 |
| Shams, M | 1 |
| Rifaat, S | 1 |
| El-Mezaien, M | 1 |
| Jainkittivong, A | 1 |
| Aneksuk, V | 1 |
| Langlais, RP | 1 |
| Blanco-Vidal, MJ | 1 |
| Catalan-Urribarrena, G | 1 |
| Lopez, JI | 1 |
| del Aguila, C | 1 |
| Magnet, A | 1 |
| Pomposo-Gaztelu, I | 1 |
| Montejo, M | 1 |
| Carneiro, PM | 1 |
| Nyawawa, ET | 1 |
| Amin, A | 1 |
| Casey, AT | 1 |
| Etherington, G | 1 |
| Coffey, GL | 1 |
| Botts, SR | 1 |
| de Leon, J | 1 |
| Hui, Z | 1 |
| Guang-Yu, M | 1 |
| Chong-Tao, X | 1 |
| Quan, Y | 1 |
| Xiao-Hu, X | 1 |
| Walker, M | 1 |
| Redeker, S | 1 |
| Studen-Pavlovich, D | 1 |
| Ranalli, DN | 1 |
| Black, JA | 1 |
| Liu, S | 1 |
| Hains, BC | 1 |
| Saab, CY | 1 |
| Waxman, SG | 1 |
| Schaub, C | 1 |
| Uebachs, M | 1 |
| Beck, H | 1 |
| van Schaik, R | 1 |
| da Silva, FH | 1 |
| Wadman, WJ | 1 |
| Zipes, DP | 1 |
| Orgain, ES | 1 |
| Ferlic, RM | 1 |
| Sellers, RD | 1 |
| Lillehei, CW | 1 |
| Eliot, RS | 1 |
| Dostert, P | 1 |
| Benedetti, MS | 1 |
| Garson, A | 1 |
| Gillette, PC | 1 |
| Johnson, JP | 1 |
| Swerdlow, M | 1 |
| Cundill, JG | 1 |
| Dworkin, SF | 1 |
| Tashiro, N | 1 |
| Takeichi, M | 2 |
| Matsushima, M | 1 |
| Kono, R | 1 |
| Ando, S | 1 |
| Mizushima, S | 1 |
| Baraczka, K | 1 |
| Molnár, G | 1 |
| Atkinson, MW | 1 |
| Guinn, D | 1 |
| Owen, J | 1 |
| Hauth, JC | 1 |
| Guerreiro, CA | 1 |
| Ramos, MC | 1 |
| Annes, M | 1 |
| Bansal, NK | 1 |
| Pendse, AK | 1 |
| Sharma, A | 1 |
| Sodani, A | 1 |
| Hada, S | 1 |
| Ieiri, I | 2 |
| Goto, W | 2 |
| Hirata, K | 2 |
| Toshitani, A | 2 |
| Imayama, S | 2 |
| Ohyama, Y | 2 |
| Yamada, H | 2 |
| Ohtsubo, K | 2 |
| Higuchi, S | 2 |
| Holt, P | 1 |
| Alves, ND | 1 |
| de Castro-Costa, CM | 1 |
| de Carvalho, AM | 1 |
| Santos, FJ | 1 |
| Silveira, DG | 1 |
| Oluwatosin, OM | 1 |
| Olabanji, JK | 1 |
| Oluwatosin, OA | 1 |
| Tijani, LA | 1 |
| Onyechi, HU | 1 |
| Prasad, A | 1 |
| Williamson, JM | 1 |
| Bertram, EH | 1 |
| Lambie, DG | 2 |
| Johnson, RH | 2 |
| Nanda, RN | 2 |
| Shakir, RA | 2 |
| Penin, H | 1 |
| Jones, JH | 1 |
| Meistrup-Larsen, KI | 1 |
| Hermann, S | 1 |
| Permin, H | 1 |
| Weisman, Y | 1 |
| Fattal, A | 1 |
| Eisenberg, Z | 1 |
| Harel, S | 1 |
| Spirer, Z | 1 |
| Harell, A | 1 |
| Dekaban, AS | 1 |
| Lehman, EJ | 1 |
| Levine, MI | 1 |
| Beckner, TF | 1 |
| Idsvoog, P | 1 |
| Fong, GR | 1 |
| Vajda, FJ | 1 |
| Merory, J | 1 |
| Bladin, PF | 1 |
| Affrime, M | 1 |
| Reidenberg, MM | 1 |
| Pezzilli, R | 1 |
| Billi, P | 1 |
| Melandri, R | 1 |
| Broccoli, PL | 1 |
| Fontana, G | 1 |
| Berrocal, A | 1 |
| Barón, JM | 1 |
| Artal, A | 1 |
| Feliu, J | 1 |
| Ricart, C | 1 |
| Higes, F | 1 |
| Mallada, J | 1 |
| Kinane, DF | 1 |
| Drummond, JR | 1 |
| Chisholm, DM | 1 |
| Fredericks, CA | 1 |
| Giannotta, SL | 1 |
| Sadun, AA | 1 |
| Beech, J | 1 |
| Fletcher, JE | 1 |
| Lizzo, F | 1 |
| Johnston, J | 1 |
| Miller, WI | 1 |
| Schmidt, D | 1 |
| Richter, K | 1 |
| Botez, MI | 1 |
| Gravel, J | 1 |
| Attig, E | 1 |
| Vézina, JL | 1 |
| Glötzner, FL | 1 |
| Friedman, AP | 1 |
| Robins, AH | 1 |
| Sharpe, JA | 1 |
| Kones, RJ | 1 |
| Phillips, JH | 1 |
| Hersh, J | 1 |
| Simopoulos, AM | 1 |
| Pinto, A | 1 |
| Uhlenhuth, EH | 1 |
| McGee, JJ | 1 |
| DeRosa, ER | 1 |
| Haghshenass, M | 1 |
| Rao, DB | 1 |
| Sharp, HL | 1 |
| Mirkin, BL | 1 |
| Love, DW | 1 |
| Salter, FJ | 1 |
| Porciello, PI | 1 |
| Zanini, S | 1 |
| Poppi, A | 1 |
| Matsuyama, Y | 1 |
| Nakagawa, M | 1 |
| Leary, PM | 1 |
| Francis, J | 1 |
| Stone, N | 1 |
| Klein, MD | 1 |
| Lown, B | 1 |
| Booker, HE | 1 |
| Tormey, A | 1 |
| Toussaint, J | 1 |
| Floris, N | 1 |
| Dam, M | 1 |
| Dimich, I | 1 |
| Steinfeld, L | 1 |
| Richman, R | 1 |
| Lasser, R | 1 |
| Gillen, HW | 1 |
| Pippinger, CE | 1 |
| Kaufmann, G | 1 |
| Hauser, K | 1 |
| Höglmeier, H | 1 |
| Wenzel, U | 1 |
| Kobayashi, K | 1 |
| Takamizawa, M | 1 |
| Kobayashi, T | 1 |
| Otaka, T | 1 |
| Fukuzawa, H | 1 |
3 reviews available for phenytoin and Chronic Disease
| Article | Year |
|---|---|
Status epilepticus: an evidence based guide.
Topics: Anticonvulsants; Chronic Disease; Critical Care; Drug Administration Routes; Emergency Treatment; Ev | 2005 |
[Biochemical mechanisms of the hepatotoxicity of psychotropic drugs].
Topics: Acute Disease; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic | 1984 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Te | 1978 |
10 trials available for phenytoin and Chronic Disease
| Article | Year |
|---|---|
Comparative trial of Aloe vera/olive oil combination cream versus phenytoin cream in the treatment of chronic wounds.
Topics: Aloe; Anti-Infective Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Humans | 2015 |
The use of topical phenytoin for healing of chronic venous ulcerations.
Topics: Administration, Cutaneous; Adult; Chronic Disease; Dermatologic Agents; Drug Administration Schedule | 2011 |
Topical phenytoin versus EUSOL in the treatment of non-malignant chronic leg ulcers.
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Borates; Chronic Disease; Colony Count, Micro | 2003 |
Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension?
Topics: Adolescent; Adult; Anticonvulsants; Cesarean Section; Chi-Square Distribution; Chronic Disease; Fema | 1995 |
Comparison of topical phenytoin with normal saline in the treatment of chronic trophic ulcers in leprosy.
Topics: Administration, Topical; Adult; Chronic Disease; Female; Humans; Leprosy; Male; Middle Aged; Phenyto | 1993 |
Topical phenytoin in wound healing.
Topics: Administration, Topical; Adult; Chronic Disease; Female; Humans; Male; Phenytoin; Skin Ulcer; Wound | 1993 |
The effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic side effects: in vivo and in vitro studies.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Cell Division; Chronic Disease; DNA; Female; Fibroblasts; | 1995 |
A comparison of topical honey and phenytoin in the treatment of chronic leg ulcers.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Child; Chronic Disease; Drug | 2000 |
Diphenylhydantoin effectiveness in the treatment of chronic schizophrenics. A double-blind controlled study with a placebo.
Topics: Administration, Oral; Adult; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, | 1974 |
Effect of phenobarbital on hyperbilirubinemia, bile acid metabolism, and microsomal enzyme activity in chronic intrahepatic cholestasis of childhood.
Topics: Bile; Bile Acids and Salts; Bilirubin; Biopsy; Child; Child, Preschool; Cholestasis; Chronic Disease | 1972 |
68 other studies available for phenytoin and Chronic Disease
| Article | Year |
|---|---|
Trophic skin ulceration in leprosy: evaluation of the efficacy of topical phenytoin sodium zinc oxide paste.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Bacterial Lo | 2014 |
The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy, | 2015 |
Pluronic P85-coated poly(butylcyanoacrylate) nanoparticles overcome phenytoin resistance in P-glycoprotein overexpressing rats with lithium-pilocarpine-induced chronic temporal lobe epilepsy.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chronic Disease; Disease Models, A | 2016 |
COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barri | 2010 |
Trigeminal neuralgia: a retrospective study of 188 Thai cases.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Carbamazepine; Chronic Diseas | 2012 |
[Left-sided hemiparesis in a diabetic patient: chronic granulomatous encephalitis due to Acanthamoeba].
Topics: Acanthamoeba; Aged; Alcoholism; Amebiasis; Anti-Infective Agents; Atrial Fibrillation; Biopsy; Brain | 2013 |
Is there a role for surgery in the management of dropped head syndrome?
Topics: Anticonvulsants; Cervical Vertebrae; Chronic Disease; Epilepsy, Frontal Lobe; Humans; Kyphosis; Magn | 2004 |
High vulnerability to acute dystonic reactions: a case of antipsychotic exposure and uncontrolled seizure activity.
Topics: Anticonvulsants; Antipsychotic Agents; Chronic Disease; Cytochrome P-450 CYP2D6; Dibenzothiazepines; | 2005 |
Phenytoin reverses the chronic stress-induced impairment of memory consolidation for water maze training and depression of LTP in rat hippocampal CA1 region, but does not affect motor activity.
Topics: Animals; Anticonvulsants; Chronic Disease; Data Interpretation, Statistical; Electrophysiology; Evok | 2005 |
Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Casse | 2005 |
Periodontal and soft tissue prevention strategies for the adolescent dental patient.
Topics: Adolescent; Amphetamines; Anticonvulsants; Central Nervous System Stimulants; Chronic Disease; Cyclo | 2006 |
Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE.
Topics: Action Potentials; Administration, Oral; Animals; Axons; Cell Count; Cervical Vertebrae; Chronic Dis | 2006 |
Diminished response of CA1 neurons to antiepileptic drugs in chronic epilepsy.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Chronic Disease; Dentate Gyrus; Disease | 2007 |
Development of tolerance to levetiracetam in rats with chronic epilepsy.
Topics: Animals; Anticonvulsants; Chromatography, Gas; Chronic Disease; Disease Models, Animal; Dose-Respons | 2008 |
Refractory paroxysmal ventricular tachycardia.
Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Electrocardiography; Heart Ventricles; Humans; Hydroc | 1967 |
Cardioversion as an adjunct to cardiac surgery.
Topics: Adult; Anticoagulants; Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Chronic Dis | 1967 |
Treatment of chronic ventricular dysrhythmias in the young.
Topics: Administration, Oral; Adolescent; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Child, | 1981 |
Acquired craniofacial features associated with chronic phenytoin therapy.
Topics: Adult; Chronic Disease; Epilepsy; Face; Female; Humans; Male; Maxillofacial Development; Phenytoin; | 1984 |
Anticonvulsant drugs used in the treatment of lancinating pain. A comparison.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Female; Humans | 1981 |
Benign chronic orofacial pain. Clinical criteria and therapeutic approaches.
Topics: Biofeedback, Psychology; Carbamazepine; Chronic Disease; Humans; Nerve Block; Orthodontic Appliances | 1983 |
Neurobiological studies of experimental diphenylhydantoin intoxication. II. Electrophysiological and electron microscopic studies of the rat cerebellum with chronic diphenylhydantoin intoxication.
Topics: Animals; Cerebellum; Chronaxy; Chronic Disease; Evoked Potentials; Female; Microscopy, Electron; Oli | 1982 |
[Five autopsied cases of chronic diphenylhydantoin intoxication -- with special reference to the distribution of cerebellar degeneration and marked degeneration of nucleus fasciculi dorsalis (author's transl)].
Topics: Adult; Cerebellum; Chronic Disease; Female; Humans; Male; Phenytoin; Spinal Cord | 1980 |
Possible drug interaction in chronic treatment of epileptic patients: serum level studies.
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Chronic Disease; Clonazepam; Drug Interac | 1980 |
Neurobiological studies of experimental diphenylhydantoin intoxication. - I. Electron microscopic investigations of the rat cerebellum with chronic diphenylhydantoin intoxication.
Topics: Animals; Axons; Cerebellar Nuclei; Cerebellum; Chronic Disease; Dendrites; Female; Microscopy, Elect | 1981 |
[Repetitive serum determinations of anticonvulsants in epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Female; Humans; Middle | 1993 |
Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study.
Topics: Adult; Aged; Anticonvulsants; Chronic Disease; Female; Gingival Hyperplasia; Humans; In Vitro Techni | 1995 |
Systemic vasculitis associated with long-term phenytoin therapy.
Topics: Antibodies, Antinuclear; Anticonvulsants; Biopsy; Chronic Disease; Epilepsy; Humans; Male; Middle Ag | 1999 |
Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain.
Topics: Analgesics; Animals; Anticonvulsants; Carbamazepine; Chronic Disease; Neuralgia; Phenytoin; Rats; Ra | 1999 |
Phenobarbital and MK-801, but not phenytoin, improve the long-term outcome of status epilepticus.
Topics: Animals; Anticonvulsants; Behavior, Animal; Chronic Disease; Dizocilpine Maleate; Excitatory Amino A | 2002 |
Therapeutic and pharmacokinetic effects of increasing phenytoin in chronic epileptics on multiple drug therapy.
Topics: Adult; Biological Availability; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Com | 1976 |
Healthy and diseased gingiva.
Topics: Adult; Child; Chronic Disease; Dental Plaque; Diabetes Complications; Gingiva; Gingival Diseases; Gi | 1975 |
Comparative trial of valproate sodium and clonazepam in chronic epilepsy.
Topics: Adult; Ataxia; Benzodiazepinones; Chronic Disease; Clonazepam; Drug Therapy, Combination; Epilepsy; | 1979 |
Chronic diphenyl hydantoin encephalopathy in mentally retarded children and adolescent with severe epilepsy.
Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Chronic Disease; Epilepsy; Female; Human | 1979 |
Decreased serum 24,25-dihydroxy vitamin D concentrations in children receiving chronic anticonvulsant therapy.
Topics: Adolescent; Calcium; Child; Child, Preschool; Chronic Disease; Dihydroxycholecalciferols; Humans; Hy | 1979 |
Effects of different dosages of anticonvulsant drugs on mental performance in patients with chronic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Chronic Disease; Dose-Response Relationship, Drug; Epilep | 1975 |
Chronic urticaria.
Topics: Chronic Disease; Cytoplasmic Granules; Ephedrine; Female; Humans; Mast Cells; Middle Aged; Phenothia | 1975 |
Drug use and distribution in a pain rehabilitation center.
Topics: Adult; Amitriptyline; Barbiturates; Chronic Disease; Diet; Female; Formularies, Hospital as Topic; H | 1975 |
Letter: Drug use in a pain rehabilitation center.
Topics: Amitriptyline; Chronic Disease; Drug Combinations; Humans; Methadone; Pain; Phenytoin; Snake Venoms | 1975 |
Fluctuations of plasma phenytoin levels on single dose and twice daily dose regimes.
Topics: Adolescent; Adult; Child; Chronic Disease; Drug Administration Schedule; Epilepsy; Female; Humans; M | 1975 |
The protein binding of some drugs in plasma from patients with alcoholic liver disease.
Topics: Alcoholism; Blood Proteins; Chronic Disease; Dapsone; Fluoresceins; Humans; Liver Diseases; Pharmace | 1975 |
Anticonvulsant-induced chronic pancreatitis. A case report.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Cytochrome P-450 Enzyme System; Epilepsy; Fr | 1992 |
[A high-grade T-cell non-Hodgkin's lymphoma in a patients with tuberous sclerosis treated with hydantoins].
Topics: Adult; Chronic Disease; Humans; Male; Mediastinal Neoplasms; Phenytoin; Precursor Cell Lymphoblastic | 1991 |
[Chronic encephalopathy induced by phenytoin].
Topics: Aged; Brain Diseases; Chronic Disease; Female; Humans; Phenytoin | 1991 |
Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia.
Topics: Adult; Cell Count; Chronic Disease; Dental Plaque; Gingival Hyperplasia; Gingivitis; Humans; Langerh | 1990 |
Dilantin-induced long-term bilateral total external ophthalmoplegia.
Topics: Adult; Cerebral Angiography; Chronic Disease; Corpus Callosum; Female; Humans; Intracranial Arteriov | 1986 |
Effect of phenytoin on the clinical signs and in vitro muscle twitch characteristics in horses with chronic intermittent rhabdomyolysis and myotonia.
Topics: Administration, Oral; Animals; Chronic Disease; Creatine Kinase; Female; Gait; Horse Diseases; Horse | 1988 |
Phenytoin chronic toxicity and associated psychosis.
Topics: Aged; Chronic Disease; Female; Humans; Phenytoin; Psychoses, Substance-Induced | 1988 |
Alternative single anticonvulsant drug therapy for refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Humans; Phenobarbital; Phenytoin; | 1986 |
Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought.
Topics: Adolescent; Cerebellar Ataxia; Cerebellum; Chronic Disease; Cognition; Electroencephalography; Elect | 1985 |
Intracellular recording of spontaneous local responses in the chronic epileptogenic focus of a rhesus monkey.
Topics: Aluminum Hydroxide; Animals; Cerebral Cortex; Chronic Disease; Electrophysiology; Haplorhini; Macaca | 1974 |
An overview of chronic recurring headache.
Topics: Acute Disease; Analgesics; Antidepressive Agents; Anxiety; Chronic Disease; Cortisone; Diuretics; Er | 1972 |
Skin melanin concentrations in schizophrenia.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Chronic Disease; Female; Humans; Male; Melanins; Phenyt | 1972 |
Editoral: Rebound nystagmus--a cerebellar sign?
Topics: Brain Diseases; Brain Stem; Cerebellar Diseases; Cerebellar Neoplasms; Chronic Disease; Cranial Foss | 1974 |
Mechanism and management of chaotic atrial mechanism.
Topics: Acute Disease; Chronic Disease; Coronary Disease; Digitalis Glycosides; Drug Therapy, Combination; E | 1974 |
Serum folate levels during anticonvulsant therapy with diphenylhydantoin.
Topics: Adult; Age Factors; Aged; Binding Sites; Chronic Disease; Erythrocytes, Abnormal; Folic Acid; Hemato | 1973 |
Suspected neurotoxicity from intravenous penicillin: a patient case.
Topics: Acute Kidney Injury; Ampicillin; Blood Urea Nitrogen; Chronic Disease; Creatine; Diazepam; Gentamici | 1972 |
[Comparison of 2 modern antiarrhythmic drugs: lidocaine and diphenylhydantoin].
Topics: Arrhythmias, Cardiac; Brain; Chronic Disease; Hemodynamics; Humans; Hypotension; Lidocaine; Necrosis | 1972 |
[Autopsy case of chronic diphenylhydantoin poisoning].
Topics: Autopsy; Cerebellum; Chronic Disease; Humans; Male; Middle Aged; Phenytoin; Poisoning | 1972 |
Recurrent convulsions in Cape Town children.
Topics: Age Factors; Brain Damage, Chronic; Child; Child, Preschool; Chronic Disease; Humans; Phenytoin; Sei | 1971 |
Diphenylhydantoin in the prevention of recurring ventricular tachycardia.
Topics: Adult; Chronic Disease; Coronary Disease; Humans; Phenytoin | 1971 |
Concurrent administration of phenobarbital and diphenylhydantoin: lack of an interference effect.
Topics: Adolescent; Adult; Child; Chronic Disease; Drug Antagonism; Epilepsy; Humans; Phenobarbital; Phenoth | 1971 |
[Ultrastructural data on electron microscopy of barbiturate induced hypertrophic gingivitis. I. Changes in the covering epithelium].
Topics: Chronic Disease; Gingival Hypertrophy; Gingivitis; Humans; Microscopy, Electron; Phenytoin | 1969 |
Number of Purkinje cells in patients with grand mal epilepsy treated with diphenylhydantoin.
Topics: Acute Disease; Autopsy; Cell Count; Cerebellum; Chronic Disease; Phenytoin | 1970 |
Treatment of recurrent paroxysmal ventricular tachycardia.
Topics: Child; Chronic Disease; Electrocardiography; Humans; Male; Phenytoin; Procainamide; Propranolol; Tac | 1970 |
Low specific gravity syndrome.
Topics: Adult; Anticonvulsants; Calcium; Chlorides; Chronic Disease; Creatinine; Epilepsy; Female; Humans; I | 1968 |
[Experience with diphenylhydantoin (antisacer) in the management of cardiac arrhythmias].
Topics: Acute Disease; Arrhythmias, Cardiac; Chronic Disease; Digitalis Glycosides; Drug Tolerance; Humans; | 1968 |
[Permanent cerebellar damage through temporary overdase of hydantoin].
Topics: Adult; Cerebellar Diseases; Chronic Disease; Electroencephalography; Epilepsy; Female; Humans; Pheny | 1969 |
[Study on long-active effect of antiepileptic agents].
Topics: Adolescent; Adult; Chronic Disease; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Seizures | 1969 |