phenytoin has been researched along with Cholestasis in 12 studies
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenytoin is a highly effective and widely prescribed anticonvulsant agent, but it can be associated with dose-related side effects and hypersensitivity reactions." | 1.32 | Phenytoin-induced toxic cholestatic hepatitis in a patient with skin lesions: case report. ( Altuntaş, Y; Erdem, L; Günes, G; Karul, S; Oztürk, B; Sengül, A; Uçak, S, 2003) |
| "Phenytoin therapy was discontinued again, with complete resolution of the hepatic abnormalities." | 1.27 | Cholestatic liver dysfunction after long-term phenytoin therapy. ( Mitros, FA; Murphy, MJ; Stein, MN; Taylor, JW, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altuntaş, Y | 1 |
| Oztürk, B | 1 |
| Erdem, L | 1 |
| Günes, G | 1 |
| Karul, S | 1 |
| Uçak, S | 1 |
| Sengül, A | 1 |
| Taylor, JW | 1 |
| Stein, MN | 1 |
| Murphy, MJ | 1 |
| Mitros, FA | 1 |
| Spechler, SJ | 1 |
| Sperber, H | 1 |
| Doos, WG | 1 |
| Koff, RS | 1 |
| Epping, J | 1 |
| Fuchshofen, M | 1 |
| Richter, E | 1 |
| de la Serna Higuera, C | 1 |
| Gil Grande, LA | 1 |
| Bárcena Marugán, R | 1 |
| Ziegler, HK | 1 |
| Sinazadeh, M | 1 |
| Walter, E | 1 |
| Weedon, AP | 2 |
| Campbell, CB | 1 |
| McGuffie, C | 1 |
| Powell, LW | 1 |
| Martin, W | 1 |
| Rickers, J | 1 |
| Keane, PM | 1 |
| Pegg, PJ | 1 |
| Johnson, E | 1 |
| Sharp, HL | 1 |
| Mirkin, BL | 1 |
1 review available for phenytoin and Cholestasis
| Article | Year |
|---|---|
[Toxic cholestatic hepatitis due to phenytoin].
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Middle Aged; Phe | 1995 |
1 trial available for phenytoin and Cholestasis
| Article | Year |
|---|---|
Effect of phenobarbital on hyperbilirubinemia, bile acid metabolism, and microsomal enzyme activity in chronic intrahepatic cholestasis of childhood.
Topics: Bile; Bile Acids and Salts; Bilirubin; Biopsy; Child; Child, Preschool; Cholestasis; Chronic Disease | 1972 |
10 other studies available for phenytoin and Cholestasis
| Article | Year |
|---|---|
Phenytoin-induced toxic cholestatic hepatitis in a patient with skin lesions: case report.
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Cholestasis; Dermatitis, Exfoliative; Femal | 2003 |
Cholestatic liver dysfunction after long-term phenytoin therapy.
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Middle Aged; Phenytoin | 1984 |
Cholestasis and toxic epidermal necrolysis associated with phenytoin sodium ingestion: the role of bile duct injury.
Topics: Adult; Bile Ducts; Cholestasis; Humans; Liver; Male; Phenytoin; Skin Diseases | 1981 |
[Enterohepatic circulation in liver diseases].
Topics: Animals; Barbiturates; Bile Acids and Salts; Biotransformation; Bisacodyl; Chloramphenicol; Cholesta | 1980 |
[Anticonvulsant drugs and liver damage (Author's transl)].
Topics: Adult; Anticonvulsants; Antitubercular Agents; Autopsy; Chemical and Drug Induced Liver Injury; Chol | 1975 |
[Problems and possible errors in monitoring drug side effects at the hospital (author's transl)].
Topics: Adult; Aged; Cholestasis; Diabetes Mellitus; Drug-Related Side Effects and Adverse Reactions; Epilep | 1978 |
Diphenylhydantoin sensitivity. a syndrome resembling infectious mononucleosis with a morbilliform rash and cholestatic hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Child; Cholestasis; Diagnosis, Differential; Drug Eruptions; | 1975 |
Cholestatic liver disease associated with diphenylhydantoin therapy. Possible pathogenic importance of altered bile salt metabolism.
Topics: Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Child; Cholestasis; Humans; Hyperlipid | 1977 |
[Cholestatic hepatosis induced by diphenylhydantoin].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Diagnosis, Differential; Drug Eruptions; | 1972 |
Estimation of thyroxine binding protein capacities using a non-electrophoretic technique.
Topics: Barbiturates; Blood Protein Electrophoresis; Buffers; Cholestasis; Female; Humans; Multiple Myeloma; | 1969 |