phenytoin has been researched along with Child Development Deviations in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the first experiment, the lower end of the malformation dose-response curves for diphenylhydantoin (DPH), trimethadione (TMD) and phenobarbital (PB) were established." | 5.27 | Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring. ( Vorhees, CV, 1983) |
| "Between 1999 and 2004, we enrolled pregnant women with epilepsy who were taking a single antiepileptic agent (carbamazepine, lamotrigine, phenytoin, or valproate) in a prospective, observational, multicenter study in the United States and the United Kingdom." | 3.75 | Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. ( Baker, GA; Browning, N; Clayton-Smith, J; Cohen, M; Combs-Cantrell, DT; Kalayjian, LA; Kanner, A; Liporace, JD; Loring, DW; Meador, KJ; Pennell, PB; Privitera, M, 2009) |
| "To compare pregnancy outcome prospectively after phenytoin and carbamazepine monotherapy with outcome in matched mother-child pairs exposed to nonteratogens to evaluate the relative fetal safety of these drugs." | 3.69 | Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy. ( Ashby, P; Czuchta, D; Einarson, T; Gardner, HA; Gladstone, D; Gladstone, R; Nulman, I; Rovet, J; Scolnik, D; Weksberg, R, 1994) |
| "Odds for epilepsy were higher among people who had positive family history (O." | 2.69 | A case control study and one year follow-up of registered epilepsy cases in a resettlement colony of North India, a developing tropical country. ( Chopra, JS; Kaur, P; Sawhney, IM; Singh, A; Suri, G, 1999) |
| "There were 73 children with seizures, 80% of whom had a greater than 50% reduction in seizure frequency following the start of simple anticonvulsant medication." | 1.32 | A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children. ( Allen, S; Burton, KJ, 2003) |
| " In the first experiment, the lower end of the malformation dose-response curves for diphenylhydantoin (DPH), trimethadione (TMD) and phenobarbital (PB) were established." | 1.27 | Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring. ( Vorhees, CV, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verrotti, A | 1 |
| Scaparrotta, A | 1 |
| Cofini, M | 1 |
| Chiarelli, F | 1 |
| Tiboni, GM | 1 |
| Meador, KJ | 2 |
| Baker, GA | 1 |
| Browning, N | 1 |
| Clayton-Smith, J | 1 |
| Combs-Cantrell, DT | 1 |
| Cohen, M | 1 |
| Kalayjian, LA | 1 |
| Kanner, A | 1 |
| Liporace, JD | 1 |
| Pennell, PB | 1 |
| Privitera, M | 1 |
| Loring, DW | 2 |
| Burton, KJ | 1 |
| Allen, S | 1 |
| Chitayat, D | 1 |
| Keisar, N | 1 |
| Legum, C | 1 |
| Vorhees, CV | 1 |
| Scolnik, D | 1 |
| Nulman, I | 1 |
| Rovet, J | 1 |
| Gladstone, D | 1 |
| Czuchta, D | 1 |
| Gardner, HA | 1 |
| Gladstone, R | 1 |
| Ashby, P | 1 |
| Weksberg, R | 1 |
| Einarson, T | 1 |
| Jeret, JS | 1 |
| Thompson, WO | 1 |
| Sawhney, IM | 1 |
| Singh, A | 1 |
| Kaur, P | 1 |
| Suri, G | 1 |
| Chopra, JS | 1 |
| McBride, MC | 1 |
| Laroia, N | 1 |
| Guillet, R | 1 |
| Gaily, E | 1 |
| Kantola-Sorsa, E | 1 |
| Granström, ML | 1 |
| Fowler, GW | 1 |
| Dumars, KW | 1 |
1 review available for phenytoin and Child Development Deviations
| Article | Year |
|---|---|
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabili | 2014 |
2 trials available for phenytoin and Child Development Deviations
| Article | Year |
|---|---|
A case control study and one year follow-up of registered epilepsy cases in a resettlement colony of North India, a developing tropical country.
Topics: Adolescent; Adult; Anticonvulsants; Case-Control Studies; Child; Craniocerebral Trauma; Developmenta | 1999 |
Electrographic seizures in neonates correlate with poor neurodevelopmental outcome.
Topics: Anticonvulsants; Asphyxia Neonatorum; Demography; Developmental Disabilities; Electroencephalography | 2000 |
9 other studies available for phenytoin and Child Development Deviations
| Article | Year |
|---|---|
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Developmental Disabilities; Dose | 2009 |
A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Developmental Disabilities; Fem | 2003 |
[Fetal phenytoin syndrome].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Brain; Developmental Disabilities; Electroence | 1982 |
Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring.
Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Developmental Disabilities; Dose-Response Re | 1983 |
Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy.
Topics: Carbamazepine; Case-Control Studies; Child; Cognition; Developmental Disabilities; Female; Humans; I | 1994 |
Neurodevelopment after in utero exposure to phenytoin and carbamazepine.
Topics: Carbamazepine; Child; Developmental Disabilities; Female; Humans; Phenytoin; Pregnancy; Prenatal Exp | 1994 |
Neurodevelopment after in utero exposure to phenytoin and carbamazepine.
Topics: Carbamazepine; Child; Developmental Disabilities; Female; Humans; Phenytoin; Pregnancy; Prenatal Exp | 1994 |
Intelligence of children of epileptic mothers.
Topics: Child, Preschool; Developmental Disabilities; Epilepsy; Female; Humans; Intelligence; Intelligence T | 1988 |
Cutis aplasia and cerebral malformation.
Topics: Cephalometry; Cerebrospinal Fluid Proteins; Developmental Disabilities; Female; Humans; Hydranenceph | 1973 |