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phenytoin and Cerebral Palsy

phenytoin has been researched along with Cerebral Palsy in 8 studies

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
"Phenytoin-induced gingival overgrowth (PIGO) is a recognized side effect in many cerebral palsy patients using diphenylhydantoin (Dph) for the control of seizures."7.67Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population. ( Jones, JE; McKown, CG; Weddell, JA, 1988)
" A more severe grade of neonatal encephalopathy, a higher number of neonatal seizures, the neonatal use of phenytoin, diffuse abnormalities on imaging, and abnormal findings on neurologic examination at neonatal discharge were all significantly (P<0."3.75The spectrum of abnormal neurologic outcomes subsequent to term intrapartum asphyxia. ( Al-Macki, N; Hall, N; Miller, SP; Shevell, M, 2009)
"Phenytoin-induced gingival overgrowth (PIGO) is a recognized side effect in many cerebral palsy patients using diphenylhydantoin (Dph) for the control of seizures."3.67Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population. ( Jones, JE; McKown, CG; Weddell, JA, 1988)
"Cerebral palsy was not diagnosed in any infant of a hypertensive mother compared with five of the controls."1.30Maternal hypertension and neurodevelopmental outcome in very preterm infants. ( Burns, YR; Gray, PH; King, JF; Mohay, HA; O'Callaghan, MJ, 1998)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Yokoyama, R1
Hayashi, R1
Umemori, Y1
Arimatsu, A1
Yuki, A1
Abe, R1
Al-Macki, N1
Miller, SP1
Hall, N1
Shevell, M1
Gray, PH1
O'Callaghan, MJ1
Mohay, HA1
Burns, YR1
King, JF1
Higashi, A1
Matsuda, I1
Sinosuka, S1
Ohtsuka, H1
Endo, F1
Maeda, T1
Ikeda, T1
Miyoshino, S1
Rodriguez-Segade, S1
de la Peña, CA1
Tutor, JC1
Paz, JM1
Fernandez, MP1
Rozas, I1
Del Río, R1
Jones, JE1
Weddell, JA1
McKown, CG1
Ota, N1
Murakami, H1
Hashimoto, K1
Watanabe, T1
Kasahara, H1
Tokuue, S1
Trojaborg, W1

Other Studies

8 other studies available for phenytoin and Cerebral Palsy

ArticleYear
Refractory Bullous Pemphigoid Improved by Discontinuation of Phenytoin as an CYP3A4 Inducer.
    Acta dermato-venereologica, 2020, 04-06, Volume: 100, Issue:8

    Topics: Aged; Anti-Inflammatory Agents; Anticonvulsants; Cerebral Palsy; Cytochrome P-450 CYP3A Inducers; Dr

2020
The spectrum of abnormal neurologic outcomes subsequent to term intrapartum asphyxia.
    Pediatric neurology, 2009, Volume: 41, Issue:6

    Topics: Anticonvulsants; Asphyxia Neonatorum; Cerebral Palsy; Female; Follow-Up Studies; Humans; Infant, New

2009
Maternal hypertension and neurodevelopmental outcome in very preterm infants.
    Archives of disease in childhood. Fetal and neonatal edition, 1998, Volume: 79, Issue:2

    Topics: Adult; Anticonvulsants; Antihypertensive Agents; Case-Control Studies; Cerebral Palsy; Child, Presch

1998
Delayed cutaneous hypersensitivity in children with severe multiple handicaps treated with phenytoin.
    European journal of pediatrics, 1978, Dec-01, Volume: 129, Issue:4

    Topics: Adolescent; B-Lymphocytes; Cerebral Palsy; Child; Child, Preschool; Disabled Persons; Humans; Immuni

1978
Carnitine deficiency associated with anticonvulsant therapy.
    Clinica chimica acta; international journal of clinical chemistry, 1989, May-15, Volume: 181, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Carnitine; Cerebral Palsy; Drug Therapy, Co

1989
Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1988, Volume: 46, Issue:5

    Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Cerebral

1988
[A case of dilantin hyperplasia associated with cerebral palsy].
    Nihon Shishubyo Gakkai kaishi, 1987, Volume: 29, Issue:1

    Topics: Adult; Cerebral Palsy; Dental Scaling; Gingival Hyperplasia; Humans; Male; Oral Hygiene; Phenytoin;

1987
Focal spike discharges in children, a longitudinal study.
    Acta paediatrica Scandinavica, 1966

    Topics: Adolescent; Aging; Central Nervous System Diseases; Cerebral Palsy; Cerebral Ventriculography; Child

1966