phenytoin has been researched along with Cerebellar Ataxia in 41 studies
Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic intoxication of phenytoin (PHT) is a well known cause of cerebellar atrophy or irreversible cerebellar ataxia." | 8.78 | [Cerebellar atrophy and persistent cerebellar ataxia after acute intoxication of phenytoin]. ( Ejima, A; Imamura, T; Sahara, M; Saito, H; Tsuburaya, K, 1992) |
| "A 30-year-old man was given high doses of phenytoin together with 4 antituberculous drugs for a seizure associated with a probable brain tuberculoma." | 7.70 | [Residual cerebellar ataxia following acute phenytoin intoxication]. ( al Beladi, K; al Jumah, M; Amene, P; Awada, A, 1999) |
| "A 42-year-old woman who presented phenytoin intoxication induced by acute hypothyroidism was reported." | 7.68 | [A case of phenytoin intoxication induced by hypothyroidism]. ( Fujitake, J; Horii, K; Ishikawa, K; Shimbo, S; Tatsuoka, Y, 1991) |
| "Reversible chronic cerebellar ataxia followed phenytoin treatment in two epileptic women." | 7.67 | Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought. ( Attig, E; Botez, MI; Gravel, J; Vézina, JL, 1985) |
| "Phenytoin has been considered a possible cause of cerebellar degeneration, especially after clinical intoxication." | 5.29 | [Cerebellar atrophy and phenytoin poisoning. An MR study]. ( Aichner, F; Bauer, G; Birbamer, G; Felber, S; Luef, G; Marosi, M, 1993) |
| "Chronic intoxication of phenytoin (PHT) is a well known cause of cerebellar atrophy or irreversible cerebellar ataxia." | 4.78 | [Cerebellar atrophy and persistent cerebellar ataxia after acute intoxication of phenytoin]. ( Ejima, A; Imamura, T; Sahara, M; Saito, H; Tsuburaya, K, 1992) |
| " Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate." | 4.77 | Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985) |
| "This report presents a 30-year-old man who developed subacute phenytoin-induced cerebellar ataxia and parkinsonism that resolved after discontinuation of the phenytoin treatment." | 3.73 | Phenytoin-induced parkinsonism. ( Acar, ZU; Ertan, S; Hanimoglu, H; Kafadar, AM; Kiziltan, G; Tanriverdi, T; Ulu, MO, 2006) |
| "A 30-year-old man was given high doses of phenytoin together with 4 antituberculous drugs for a seizure associated with a probable brain tuberculoma." | 3.70 | [Residual cerebellar ataxia following acute phenytoin intoxication]. ( al Beladi, K; al Jumah, M; Amene, P; Awada, A, 1999) |
| "A 42-year-old woman who presented phenytoin intoxication induced by acute hypothyroidism was reported." | 3.68 | [A case of phenytoin intoxication induced by hypothyroidism]. ( Fujitake, J; Horii, K; Ishikawa, K; Shimbo, S; Tatsuoka, Y, 1991) |
| "Reversible chronic cerebellar ataxia followed phenytoin treatment in two epileptic women." | 3.67 | Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought. ( Attig, E; Botez, MI; Gravel, J; Vézina, JL, 1985) |
| "Clinical signs of ataxia can persist without radiological evidence of cerebellar atrophy, and cerebellar atrophy is seen without any clinical evidence of cerebellar dysfunction." | 2.82 | Phenytoin and damage to the cerebellum - a systematic review of published cases. ( Bradberry, SM; Day, R; Ferner, R, 2022) |
| " The observed cerebellar ataxia might be due to long-term administration of phenytoin." | 1.35 | [Case of juvenile myoclonic epilepsy misdiagnosed as simple partial seizure for more than 60 years]. ( Komori, T; Mizoi, Y; Shimazu, K; Sumita, N; Tamura, N; Yamamoto, T, 2009) |
| " We consider his cerebellar symptoms and peripheral neuropathy could be attributable to the long-term use of multiple anticonvulsants, i." | 1.29 | [Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy]. ( Kubota, M; Nagata, J, 1993) |
| "Phenytoin has been considered a possible cause of cerebellar degeneration, especially after clinical intoxication." | 1.29 | [Cerebellar atrophy and phenytoin poisoning. An MR study]. ( Aichner, F; Bauer, G; Birbamer, G; Felber, S; Luef, G; Marosi, M, 1993) |
| " This would be a manifestation of an independent Phenytoin effect in the high toxic dosage respectively in withdrawal." | 1.26 | [EEG in phenytoin intoxication (author's transl)]. ( Mayr, N; Wessely, P, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (65.85) | 18.7374 |
| 1990's | 11 (26.83) | 18.2507 |
| 2000's | 2 (4.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Ferner, R | 1 |
| Day, R | 1 |
| Bradberry, SM | 1 |
| Mizoi, Y | 1 |
| Sumita, N | 1 |
| Yamamoto, T | 1 |
| Komori, T | 1 |
| Tamura, N | 1 |
| Shimazu, K | 1 |
| Ertan, S | 1 |
| Ulu, MO | 1 |
| Hanimoglu, H | 1 |
| Tanriverdi, T | 1 |
| Kafadar, AM | 1 |
| Acar, ZU | 1 |
| Kiziltan, G | 1 |
| Feuerstein, T | 1 |
| von Reutern, GM | 1 |
| Cramer, H | 1 |
| Lindvall, O | 1 |
| Nilsson, B | 1 |
| Campbell, WW | 1 |
| Wessely, P | 2 |
| Mayr, N | 2 |
| Binder, H | 1 |
| Klingler, D | 1 |
| Rosich Pla, A | 1 |
| Villa, AM | 1 |
| Sica, RE | 1 |
| Ng, WK | 1 |
| Tan, CT | 1 |
| Young, GB | 1 |
| Oppenheimer, SR | 1 |
| Gordon, BA | 1 |
| Wells, GA | 1 |
| Assis, LP | 1 |
| Kreeft, JH | 1 |
| Lohuis, NA | 1 |
| Blume, WT | 1 |
| Kubota, M | 1 |
| Nagata, J | 1 |
| Luef, G | 1 |
| Marosi, M | 1 |
| Felber, S | 1 |
| Birbamer, G | 1 |
| Aichner, F | 1 |
| Bauer, G | 1 |
| Awada, A | 1 |
| Amene, P | 1 |
| al Jumah, M | 1 |
| al Beladi, K | 1 |
| Pulliainen, V | 1 |
| Jokelainen, M | 1 |
| Hedman, C | 1 |
| Pammo, O | 1 |
| Ziegler, DK | 1 |
| Livingston, S | 1 |
| Pruce, I | 1 |
| Pauli, LL | 1 |
| Livingston, HL | 1 |
| Herberg, KP | 1 |
| Nagayama, M | 1 |
| Matsumura, K | 1 |
| Hokazu, Y | 1 |
| Maruyama, T | 1 |
| Omame, M | 1 |
| Okuda, T | 1 |
| Imamura, T | 1 |
| Ejima, A | 1 |
| Sahara, M | 1 |
| Saito, H | 1 |
| Tsuburaya, K | 1 |
| Horii, K | 1 |
| Fujitake, J | 1 |
| Tatsuoka, Y | 1 |
| Ishikawa, K | 1 |
| Shimbo, S | 1 |
| Teta, D | 1 |
| Uldry, PA | 1 |
| Regli, F | 1 |
| Avasthi, R | 1 |
| Jain, AP | 1 |
| Reynolds, EH | 1 |
| Trimble, MR | 1 |
| Ramsay, RE | 1 |
| Baier, WK | 1 |
| Beck, U | 1 |
| Hirsch, W | 1 |
| Botez, MI | 1 |
| Gravel, J | 1 |
| Attig, E | 1 |
| Vézina, JL | 1 |
| Afifi, AK | 1 |
| Van Allen, MW | 1 |
| Rawson, MD | 1 |
| Greenberg, JO | 1 |
| Selhorst, JB | 1 |
| Kaufman, B | 1 |
| Horwitz, SJ | 1 |
| Igata, A | 1 |
| Riley, CG | 1 |
| Gerber, N | 1 |
| Lynn, R | 1 |
| Oates, J | 1 |
| Haring, RD | 1 |
| Simmons, FB | 1 |
| Thomas, DJ | 1 |
| Vallarta, JM | 1 |
| Bell, DB | 1 |
| Reichert, A | 1 |
| Ito, K | 1 |
| Miyagishi, T | 1 |
| Takahata, N | 1 |
| Kruse, R | 1 |
| La Rosa, JC | 1 |
| Brown, WV | 1 |
| Frommer, PL | 1 |
| Levy, RI | 1 |
6 reviews available for phenytoin and Cerebellar Ataxia
| Article | Year |
|---|---|
Phenytoin and damage to the cerebellum - a systematic review of published cases.
Topics: Adult; Ataxia; Atrophy; Cerebellar Ataxia; Cerebellar Diseases; Cerebellum; Humans; Phenytoin | 2022 |
Toxicity to the nervous system of diphenylhydantoin: a review.
Topics: Adrenal Cortex Hormones; Animals; Cardiovascular Diseases; Cerebellar Ataxia; Cerebellar Diseases; C | 1978 |
[Cerebellar atrophy and persistent cerebellar ataxia after acute intoxication of phenytoin].
Topics: Adult; Atrophy; Cerebellar Ataxia; Cerebellum; Humans; Male; Phenytoin; Tomography, X-Ray Computed | 1992 |
Adverse neuropsychiatric effects of anticonvulsant drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba | 1985 |
Use of phenytoin and carbamazepine in treatment of epilepsy.
Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognitio | 1986 |
[Ataxia associated with infections and toxicosis].
Topics: Abdomen; Adult; Animals; Ataxia; Cerebellar Ataxia; Cerebrovascular Disorders; Demyelinating Disease | 1971 |
35 other studies available for phenytoin and Cerebellar Ataxia
| Article | Year |
|---|---|
[Case of juvenile myoclonic epilepsy misdiagnosed as simple partial seizure for more than 60 years].
Topics: Aged; Cerebellar Ataxia; Diagnostic Errors; Electroencephalography; Electromyography; Epilepsies, Pa | 2009 |
Phenytoin-induced parkinsonism.
Topics: Adult; Anticonvulsants; Cerebellar Ataxia; Humans; Magnetic Resonance Imaging; Male; Parkinsonian Di | 2006 |
[Phenytoin poisoning in a degradation disorder, report of a case with cerebellar atrophy].
Topics: Adult; Atrophy; Cerebellar Ataxia; Cerebellum; Cholestyramine Resin; Electroencephalography; Epileps | 1983 |
Cerebellar atrophy following phenytoin intoxication.
Topics: Adult; Atrophy; Cerebellar Ataxia; Cerebellum; Humans; Male; Phenytoin; Tomography, X-Ray Computed | 1984 |
Periodic alternating nystagmus in phenytoin intoxication.
Topics: Alcoholism; Cerebellar Ataxia; Epilepsy, Post-Traumatic; Humans; Male; Middle Aged; Nystagmus, Patho | 1980 |
[EEG in phenytoin intoxication (author's transl)].
Topics: Adult; Central Nervous System Diseases; Cerebellar Ataxia; Dose-Response Relationship, Drug; Electro | 1981 |
[Neurological signs in diphenylhydantoin intoxication (case reports and review) (author's transl)].
Topics: Adult; Biopsy; Cerebellar Ataxia; Electroencephalography; Epilepsy; Evoked Potentials; Female; Human | 1981 |
[Permanent cerebellar degeneration secondary to diphenylhydantoin (author's transl)].
Topics: Adult; Alcoholism; Cerebellar Ataxia; Humans; Male; Phenytoin; Seizures | 1980 |
[Persistent cerebellar ataxia after toxic administration of diphenylhydantoin].
Topics: Arachnoid Cysts; Brain Diseases; Cerebellar Ataxia; Epilepsy; Humans; Male; Middle Aged; Phenytoin; | 1994 |
Paroxysmal cerebellar ataxia: use of phenytoin as a provocation test.
Topics: Adult; Cerebellar Ataxia; Humans; Male; Phenytoin | 1994 |
Ataxia in institutionalized patients with epilepsy.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Anticonvulsants; Ataxia; Cerebellar Ataxia; Epilepsy; | 1994 |
[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy].
Topics: Adult; Anticonvulsants; Brain; Cerebellar Ataxia; Drug Therapy, Combination; Epilepsy, Generalized; | 1993 |
[Cerebellar atrophy and phenytoin poisoning. An MR study].
Topics: Adult; Anticonvulsants; Atrophy; Cerebellar Ataxia; Cerebellum; Dose-Response Relationship, Drug; Dr | 1993 |
[Residual cerebellar ataxia following acute phenytoin intoxication].
Topics: Adult; Anticonvulsants; Atrophy; Brain; Brain Neoplasms; Cerebellar Ataxia; Cerebellum; Epilepsy; Hu | 1999 |
[Cerebellar damage caused by phenytoin intoxication].
Topics: Adolescent; Anticonvulsants; Cerebellar Ataxia; Drug Monitoring; Epilepsy; Female; Humans; Phenytoin | 1997 |
The medical treatment of epilepsy: managing side effects of antiepileptic drugs.
Topics: Anticonvulsants; Blood; Cerebellar Ataxia; Child; Child, Preschool; Dextroamphetamine; Drug Eruption | 1979 |
Delayed and insidious onset of diphenylhydantoin toxicity.
Topics: Adolescent; Adult; Animals; Cerebellar Ataxia; Drug Interactions; Electroencephalography; Epilepsy; | 1975 |
[Case of acute encephalopathy due to atropine and phenytoin poisoning diagnosed by urine and blood analysis].
Topics: Acute Disease; Adult; Atropine; Cerebellar Ataxia; Chromatography, High Pressure Liquid; Consciousne | 1992 |
[A case of phenytoin intoxication induced by hypothyroidism].
Topics: Acute Disease; Adult; Cerebellar Ataxia; Female; Humans; Hypothyroidism; Phenytoin; Thyroid Gland; T | 1991 |
[Reversible ophthalmoplegia, cerebellar syndrome and vigilance disorders following phenytoin poisoning].
Topics: Adult; Cerebellar Ataxia; Charcoal; Cognition Disorders; Humans; Male; Ophthalmoplegia; Phenytoin; P | 1990 |
Phenytoin--isoniazid interaction.
Topics: Adult; Cerebellar Ataxia; Drug Synergism; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; | 1989 |
CT findings following diphenylhydantoin intoxication.
Topics: Adult; Cerebellar Ataxia; Child; Epilepsy; Female; Humans; Phenytoin; Tomography, X-Ray Computed | 1985 |
Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought.
Topics: Adolescent; Cerebellar Ataxia; Cerebellum; Chronic Disease; Cognition; Electroencephalography; Elect | 1985 |
Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.
Topics: Adult; Brain; Cerebellar Ataxia; Cerebral Ventriculography; Chlorpromazine; Diplopia; Electroconvuls | 1968 |
Diphenylhydantoin intoxication and cerebrospinal fluid protein.
Topics: Adenosine Triphosphatases; Adult; Cerebellar Ataxia; Cerebrospinal Fluid Proteins; Epilepsy; Female; | 1968 |
The neurological effects of methyl bromide poisoning.
Topics: Adult; Amobarbital; Brain Diseases; Bromine; Cerebellar Ataxia; Diazepam; Dimercaprol; Electroenceph | 1971 |
Diphenylhydantoin-induced cerebellar degeneration.
Topics: Adolescent; Cerebellar Ataxia; Cerebellar Diseases; Child; Electroencephalography; Epilepsy; Female; | 1972 |
Chronic hydantoin intoxication: case report.
Topics: Adult; Cerebellar Ataxia; Cognition Disorders; Epilepsy; Female; Humans; Nystagmus, Pathologic; Phen | 1972 |
Acute intoxication with 5,5-diphenylhydantoin (Dilantin) associated with impairment of biotransformation. Plasma levels and urinary metabolites; and studies in healthy volunteers.
Topics: Administration, Oral; Adult; Biotransformation; Cerebellar Ataxia; Epilepsy, Tonic-Clonic; Female; H | 1972 |
Cerebellar defects detectable by electronystagmography calibration.
Topics: Adolescent; Adult; Aged; Astrocytoma; Blindness; Brain Diseases; Cerebellar Ataxia; Cerebellar Disea | 1973 |
Brain damage after lithium and phenytoin.
Topics: Brain Diseases; Cerebellar Ataxia; Epilepsy; Female; Humans; Lithium; Phenytoin; Purkinje Cells | 1974 |
Progressive encephalopathy due to chronic hydantoin intoxication.
Topics: Adolescent; Brain Diseases; Cerebellar Ataxia; Cerebellum; Child; Electroencephalography; Face; Fema | 1974 |
An electron microscopic study of axonal changes in the cerebellum of diphenyl-hydantoin intoxicated rats. The formation of the so-called "honeycomb structure" in the axoplasm.
Topics: Animals; Axons; Cerebellar Ataxia; Cerebellum; Cytoplasm; Injections, Intramuscular; Male; Microscop | 1970 |
[Unusual but dangerous hydantoin side effects].
Topics: Cerebellar Ataxia; Child; Epilepsy, Temporal Lobe; Humans; Male; Phenytoin | 1967 |
Clofibrate-induced ventricular arrhythmia.
Topics: Anticholesteremic Agents; Arrhythmias, Cardiac; Catecholamines; Cerebellar Ataxia; Creatine Kinase; | 1969 |