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phenytoin and Carcinoma, Squamous Cell

phenytoin has been researched along with Carcinoma, Squamous Cell in 10 studies

Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin."7.70Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 1999)
"Agranulocytosis is a rare side effect of phenytoin treatment."7.68Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction? ( McClune, GL; Sharafuddin, MJ; Spanheimer, RG, 1991)
"A few case reports of oral squamous cell carcinomas arising from regions of phenytoin induced gingival overgrowth (GO), and overexpression of mitogenic factors and p53 have presented this condition as a pathology with potential to transform into malignancy."5.39Comprehensive mutation analysis of PIK3CA, p14ARF, p16INK4a and p21Waf1/Cip1 genes is suggestive of a non- neoplastic nature of phenytoin induced gingival overgrowth. ( Jayesh, RS; Kumar, KS; Muthupalani, RS; Rajendran, S; Ramanathan, A; Swamikannu, B, 2013)
"Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin."3.70Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 1999)
"A case is described of a squamous cell carcinoma arising in an area of phenytoin-induced gingival hyperplasia."3.69Oral squamous cell carcinoma arising in phenytoin-induced hyperplasia. ( Brown, A; McLoughlin, P; Newman, L, 1995)
"Agranulocytosis is a rare side effect of phenytoin treatment."3.68Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction? ( McClune, GL; Sharafuddin, MJ; Spanheimer, RG, 1991)
"A few case reports of oral squamous cell carcinomas arising from regions of phenytoin induced gingival overgrowth (GO), and overexpression of mitogenic factors and p53 have presented this condition as a pathology with potential to transform into malignancy."1.39Comprehensive mutation analysis of PIK3CA, p14ARF, p16INK4a and p21Waf1/Cip1 genes is suggestive of a non- neoplastic nature of phenytoin induced gingival overgrowth. ( Jayesh, RS; Kumar, KS; Muthupalani, RS; Rajendran, S; Ramanathan, A; Swamikannu, B, 2013)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's5 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Swamikannu, B1
Kumar, KS1
Jayesh, RS1
Rajendran, S1
Muthupalani, RS1
Ramanathan, A1
Ahmed, I1
Biswas, A1
Krishnamurthy, S1
Julka, PK1
Moore, JL1
Paterson, IC1
Newman, H1
Venables, S1
McLoughlin, P1
Newman, L1
Brown, A1
Recuenco, I1
Espinosa, E1
GarcĂ­a, B1
Carcas, A1
Cockey, GH1
Amann, ST1
Reents, SB1
Lynch, JW1
Saito, K1
Mori, S1
Tanda, N1
Sakamoto, S1
Miuller, NR1
Tsyrlina, EV1
Ostroumova, MN1
Shemerovskaia, TG1
Sharafuddin, MJ1
Spanheimer, RG1
McClune, GL1
Keefe, M1
Wakeel, RA1
Dick, DC1

Other Studies

10 other studies available for phenytoin and Carcinoma, Squamous Cell

ArticleYear
Comprehensive mutation analysis of PIK3CA, p14ARF, p16INK4a and p21Waf1/Cip1 genes is suggestive of a non- neoplastic nature of phenytoin induced gingival overgrowth.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:5

    Topics: Base Sequence; Carcinoma, Squamous Cell; Class I Phosphatidylinositol 3-Kinases; Cross-Sectional Stu

2013
Toxic epidermal necrolysis in a patient receiving concurrent phenytoin and whole brain and thoracic radiotherapy.
    Saudi medical journal, 2014, Volume: 35, Issue:11

    Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Male; Middle Age

2014
Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients.
    British journal of cancer, 1981, Volume: 44, Issue:4

    Topics: Carcinoma, Squamous Cell; Esophageal Neoplasms; Half-Life; Head and Neck Neoplasms; Humans; Kinetics

1981
Oral squamous cell carcinoma arising in phenytoin-induced hyperplasia.
    British dental journal, 1995, Mar-11, Volume: 178, Issue:5

    Topics: Adult; Carcinoma, Squamous Cell; Fatal Outcome; Gingival Hyperplasia; Gingival Neoplasms; Humans; Ja

1995
Effect of dexamethasone on the decrease of serum phenytoin concentrations.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:9

    Topics: Anti-Inflammatory Agents; Anticonvulsants; Carcinoma, Squamous Cell; Dexamethasone; Humans; Lung Neo

1995
Stevens-Johnson syndrome resulting from whole-brain radiation and phenytoin.
    American journal of clinical oncology, 1996, Volume: 19, Issue:1

    Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Squamous Cell; Chemoprevention; Cranial Irradiation; De

1996
Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin.
    Journal of periodontology, 1999, Volume: 70, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Biomarkers, Tumor; Calcium Channel Blockers; Carcinoma, Squamous

1999
[The effect of diphenine on the growth and metastasis of experimental malignant tumors].
    Voprosy onkologii, 1975, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Female; Immunologic

1975
Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction?
    Acta haematologica, 1991, Volume: 86, Issue:4

    Topics: Agranulocytosis; Brain Neoplasms; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury;

1991
Death from metastatic, cutaneous, squamous cell carcinoma in autosomal recessive dystrophic epidermolysis bullosa despite permanent inpatient care.
    Dermatologica, 1988, Volume: 177, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Carcinoma, Squamous Cell; Epidermolysis Bullosa; Fatty Acids; Female;

1988