phenytoin has been researched along with Carcinoma, Non-Small Cell Lung in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "There are few reports about Stevens-Johnson syndrome, a bullous form of erythema multiforme, that can develop in patients treated with cranial irradiation and antiepileptic drugs, especially with phenytoin." | 3.72 | Toxic epidermal necrolysis after cranial radiotherapy and phenytoin treatment. ( Demirkesen, C; Koca, S; Oner Dincbas, F; Uzel, O; Yörük, S, 2004) |
| " Concomitant use of erlotinib and the antiepileptic drug phenytoin, an inducer of CYP3A4, may result in a drug-drug interaction accompanied by changes in the blood concentrations of both drugs." | 1.43 | Drug interaction between erlotinib and phenytoin for brain metastases in a patient with nonsmall cell lung cancer. ( Homma, M; Kaburagi, T; Kurosawa, A; Ohgami, M, 2016) |
| "Brain metastases are a frequent finding in patients with advanced non-small cell lung cancer and concomitant administration of antiepileptic and chemotherapeutic drugs or epidermal growth factor receptor (EGFR) inhibitor is necessary in many cases." | 1.34 | Significant drug interaction: phenytoin toxicity due to erlotinib. ( Gabizon, A; Gipps, M; Grenader, T; Shavit, L, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohgami, M | 1 |
| Kaburagi, T | 1 |
| Kurosawa, A | 1 |
| Homma, M | 1 |
| Pepe, C | 1 |
| Marchionni, C | 1 |
| Aguiar, D | 1 |
| Pazo, R | 1 |
| Durán, I | 1 |
| Terrasa, J | 1 |
| Arrivi, A | 1 |
| Manzano, H | 1 |
| Martín, J | 1 |
| Rifá, J | 1 |
| Oner Dincbas, F | 1 |
| Yörük, S | 1 |
| Demirkesen, C | 1 |
| Uzel, O | 1 |
| Koca, S | 1 |
| Grenader, T | 1 |
| Gipps, M | 1 |
| Shavit, L | 1 |
| Gabizon, A | 1 |
| Kawamura, KI | 1 |
| Grabowski, D | 1 |
| Weizer, K | 1 |
| Bukowski, R | 1 |
| Ganapathi, R | 1 |
| Frangogiannis, NG | 1 |
| Boridy, I | 1 |
| Mazhar, M | 1 |
| Mathews, R | 1 |
| Gangopadhyay, S | 1 |
| Cate, T | 1 |
| van der Graaf, WT | 1 |
| van Loon, AJ | 1 |
| Postmus, PE | 1 |
| Sleijfer, DT | 1 |
8 other studies available for phenytoin and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Drug interaction between erlotinib and phenytoin for brain metastases in a patient with nonsmall cell lung cancer.
Topics: Brain; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 CYP1A2 Inducers; Cytochrome | 2016 |
A case of phenytoin-induced encephalopathy in a mathematician with Stage IV NSCLC.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Neurotoxicity Syndromes; Pheny | 2011 |
Toxic epidermal necrolysis in patients receiving anticonvulsants and cranial irradiation: a risk to consider.
Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cranial Irradiation; Humans; Lung | 2004 |
Toxic epidermal necrolysis after cranial radiotherapy and phenytoin treatment.
Topics: Aged; Anticonvulsants; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; C | 2004 |
Significant drug interaction: phenytoin toxicity due to erlotinib.
Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Erlotinib Hydro | 2007 |
Modulation of vinblastine cytotoxicity by dilantin (phenytoin) or the protein phosphatase inhibitor okadaic acid involves the potentiation of anti-mitotic effects and induction of apoptosis in human tumour cells.
Topics: Anticonvulsants; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Drug | 1996 |
Cyclophosphamide in the treatment of toxic epidermal necrolysis.
Topics: Adult; Anticonvulsants; Body Surface Area; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cyclopho | 1996 |
[2 patients with brain metastases who became pregnant during phenytoin administration].
Topics: Abortion, Therapeutic; Adult; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Choriocarcinoma; Cont | 1992 |