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phenytoin and Canine Diseases

phenytoin has been researched along with Canine Diseases in 22 studies

Research Excerpts

ExcerptRelevanceReference
" Further, for dogs given phenobarbital, there was a sixfold variation between dosage and achieved serum concentration, whereas dogs given primidone manifested even greater variability between dosage and serum concentration."5.27Serum concentrations and efficacy of phenytoin, phenobarbital, and primidone in canine epilepsy. ( Farnbach, GC, 1984)
" Using a PEG 3350 screen combined with detergents, and developed from our experiments with an IgG2a kappa antibody specific for canine lymphoma cells, crystals have now been obtained of two of these four immunoglobulins, an antiphenytoin and an antiphenobarbital antibody."3.69Crystallization of intact monoclonal antibodies. ( Harris, LJ; McPherson, A; Skaletsky, E, 1995)
"During earlier investigations of the hepatic effects in dogs of long-term administration of phenytoin alone or in combination with primidone, erythrocytic macrocytosis, neutropenia, neutrophilic hypersegmentation, and thrombocytopenia were observed."3.68Hematologic values and plasma and tissue folate concentrations in dogs given phenytoin on a long-term basis. ( Bunch, SE; Cullen, JM; Easley, JR, 1990)
"Dogs with seizure disorders have a decreased lifespan compared to the general population, and epileptic dogs with SE have a significantly abbreviated lifespan compared to epileptics that do not experience SE."2.55Status epilepticus in dogs and cats, part 2: treatment, monitoring, and prognosis. ( Blades Golubovic, S; Rossmeisl, JH, 2017)
"Palatolingual myokymia has only been reported in one human being."1.36Inspiratory stridor secondary to palatolingual myokymia in a Maltese dog. ( Bavegems, V; Bhatti, SF; Gielen, IM; Polis, I; Van Ham, LM; Van Soens, I; Vanhaesebrouck, AE; Vercauteren, G, 2010)
" The dosage of anticonvulsant drug was found to modify certain test results."1.27Compromised hepatic function in dogs treated with anticonvulsant drugs. ( Baldwin, BH; Bunch, SE; Hornbuckle, WE; Tennant, BC, 1984)
" Further, for dogs given phenobarbital, there was a sixfold variation between dosage and achieved serum concentration, whereas dogs given primidone manifested even greater variability between dosage and serum concentration."1.27Serum concentrations and efficacy of phenytoin, phenobarbital, and primidone in canine epilepsy. ( Farnbach, GC, 1984)
"Satisfactory clinical management of myotonia congenita can be achieved with procainamide."1.27Myotonia in a chow chow. ( Amann, JF; Hankison, JK; Tomlinson, J, 1985)
"dog was presented because of a convulsion."1.25Astrocytoma in a dog causing convulsions. ( Berryman, FC; de Lahunta, A, 1975)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199016 (72.73)18.7374
1990's3 (13.64)18.2507
2000's0 (0.00)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blades Golubovic, S1
Rossmeisl, JH1
Vanhaesebrouck, AE1
Bhatti, SF1
Bavegems, V1
Gielen, IM1
Van Soens, I1
Vercauteren, G1
Polis, I1
Van Ham, LM1
Bischoff, K1
Jaeger, R1
Ebel, JG1
Bunch, SE4
Baldwin, BH2
Hornbuckle, WE3
Tennant, BC3
Farnbach, GC1
Schulman, J1
Holliday, TA1
Castleman, WL2
Harris, LJ1
Skaletsky, E1
McPherson, A1
Rost, DR1
Baker, R1
Jenkins, WL1
Clark, DR1
Sanders, JE1
Yeary, RA1
Fenner, WR1
Powers, JD1
Culpin, PA1
Nash, AS1
Thompson, H1
Bogan, JA1
Berryman, FC1
de Lahunta, A1
Overduin, LM1
Easley, JR1
Cullen, JM1
Belpaire, FM1
De Rick, A1
Dello, C1
Fraeyman, N1
Bogaert, MG1
Conway, MB1
Center, SA1
Frey, HH1
Löscher, W1
Amann, JF1
Tomlinson, J1
Hankison, JK1
Averill, DR1

Reviews

4 reviews available for phenytoin and Canine Diseases

ArticleYear
Status epilepticus in dogs and cats, part 2: treatment, monitoring, and prognosis.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2017, Volume: 27, Issue:3

    Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Dog Diseases; Dogs; Electroencephalography; Phenytoin;

2017
Seizure disorders.
    The Veterinary clinics of North America. Small animal practice, 1980, Volume: 10, Issue:1

    Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephob

1980
A review of drugs affecting the heart.
    Journal of the American Veterinary Medical Association, 1977, Jul-01, Volume: 171, Issue:1

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Calcium; Catecholamines; Cats; Digitalis Glycosides; Diu

1977
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
    Journal of veterinary pharmacology and therapeutics, 1985, Volume: 8, Issue:3

    Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; E

1985

Trials

1 trial available for phenytoin and Canine Diseases

ArticleYear
Clinical trial on sustained-release phenytoin. Preliminary results of the open, non-controlled study. The Phenytoin Trial Group on Canine Epilepsy.
    Tijdschrift voor diergeneeskunde, 1992, Volume: 117 Suppl 1

    Topics: Animals; Delayed-Action Preparations; Dog Diseases; Dogs; Epilepsy; Phenytoin

1992

Other Studies

17 other studies available for phenytoin and Canine Diseases

ArticleYear
Inspiratory stridor secondary to palatolingual myokymia in a Maltese dog.
    The Journal of small animal practice, 2010, Volume: 51, Issue:3

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Electromyography; Facial Muscles; Fatal Outcome; Male;

2010
An unusual case of relay pentobarbital toxicosis in a dog.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2011, Volume: 7, Issue:3

    Topics: Adipose Tissue; Animals; Anticonvulsants; Coma; Dog Diseases; Dogs; Female; Gas Chromatography-Mass

2011
Compromised hepatic function in dogs treated with anticonvulsant drugs.
    Journal of the American Veterinary Medical Association, 1984, Feb-15, Volume: 184, Issue:4

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combin

1984
Serum concentrations and efficacy of phenytoin, phenobarbital, and primidone in canine epilepsy.
    Journal of the American Veterinary Medical Association, 1984, May-01, Volume: 184, Issue:9

    Topics: Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidon

1984
Epileptic seizures controlled with paramethadione/primidone.
    Veterinary medicine, small animal clinician : VM, SAC, 1981, Volume: 76, Issue:6

    Topics: Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Male; Oxazoles; Phenytoin; Primido

1981
Hepatic cirrhosis associated with long-term anticonvulsant drug therapy in dogs.
    Journal of the American Veterinary Medical Association, 1982, Aug-15, Volume: 181, Issue:4

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Female; Liver; Liver Cirrhosis; Male; Microscopy, Elec

1982
Crystallization of intact monoclonal antibodies.
    Proteins, 1995, Volume: 23, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antibody Specificity; Crystallization; Crysta

1995
Gingival hyperplasia induced by sodium diphenylhydantoin in the dog: a case report.
    Veterinary medicine, small animal clinician : VM, SAC, 1978, Volume: 73, Issue:5

    Topics: Animals; Dog Diseases; Dogs; Female; Gingival Hyperplasia; Phenytoin

1978
Interaction of phenytoin with chloramphenicol or pentobarbital in the dog.
    Journal of the American Veterinary Medical Association, 1979, Jul-15, Volume: 175, Issue:2

    Topics: Administration, Oral; Animals; Cerebellar Diseases; Chloramphenicol; Dog Diseases; Dogs; Drug Intera

1979
Anaesthetic death in a four-and-a-half-year-old Alsation.
    The Veterinary record, 1978, Sep-16, Volume: 103, Issue:12

    Topics: Anesthesia, Intravenous; Animals; Dog Diseases; Dogs; Female; Heart Arrest; Phenobarbital; Phenytoin

1978
Phenytoin toxicity: a fatal case in a dog with hepatitis and jaundice.
    The Veterinary record, 1977, Apr-02, Volume: 100, Issue:14

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dog Diseases; Dogs; Jaundice; Liver; Male; Phenytoi

1977
Astrocytoma in a dog causing convulsions.
    The Cornell veterinarian, 1975, Volume: 65, Issue:2

    Topics: Animals; Astrocytoma; Brain; Brain Neoplasms; Dexamethasone; Dog Diseases; Dogs; Male; Phenytoin; Se

1975
Hematologic values and plasma and tissue folate concentrations in dogs given phenytoin on a long-term basis.
    American journal of veterinary research, 1990, Volume: 51, Issue:11

    Topics: Animals; Blood Cell Count; Dog Diseases; Dogs; Erythrocytes; Female; Folic Acid; Folic Acid Deficien

1990
Alpha 1-acid glycoprotein and serum binding of drugs in healthy and diseased dogs.
    Journal of veterinary pharmacology and therapeutics, 1987, Volume: 10, Issue:1

    Topics: Animals; Blood Sedimentation; Diazepam; Digitoxin; Dog Diseases; Dogs; Female; Inflammation; Lidocai

1987
Toxic hepatopathy and intrahepatic cholestasis associated with phenytoin administration in combination with other anticonvulsant drugs in three dogs.
    Journal of the American Veterinary Medical Association, 1987, Jan-15, Volume: 190, Issue:2

    Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dog Dis

1987
Myotonia in a chow chow.
    Journal of the American Veterinary Medical Association, 1985, Aug-15, Volume: 187, Issue:4

    Topics: Animals; Biopsy; Dog Diseases; Dogs; Electromyography; Female; Muscles; Myotonia Congenita; Phenytoi

1985
Treatment of status epilepticus in dogs with diazepam sodium.
    Journal of the American Veterinary Medical Association, 1970, Feb-15, Volume: 156, Issue:4

    Topics: Animals; Barbiturates; Diazepam; Dog Diseases; Dogs; Epilepsy; Female; Injections, Intravenous; Male

1970