Page last updated: 2024-10-21

phenytoin and Cancer of Pancreas

phenytoin has been researched along with Cancer of Pancreas in 20 studies

Research Excerpts

ExcerptRelevanceReference
"This trial explores SM-88 used with methoxsalen, phenytoin, and sirolimus (MPS) in pretreated metastatic pancreatic ductal adenocarcinoma (mPDAC) METHODS: Forty-nine patients were randomized to daily 460 or 920 mg oral SM-88 with MPS (SM-88 Regimen)."5.51A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond. ( Chung, V; Hartley, ML; Kim, DW; Kim, S; Noel, MS; Ocean, AJ; Philip, PA; Picozzi, VJ; Staszewski, H; Van Tornout, JM; Wang-Gillam, A; Wong, S, 2022)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199018 (90.00)18.7374
1990's1 (5.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Noel, MS1
Kim, S1
Hartley, ML1
Wong, S1
Picozzi, VJ1
Staszewski, H1
Kim, DW1
Van Tornout, JM1
Philip, PA1
Chung, V1
Ocean, AJ1
Wang-Gillam, A1
DESOUSA, RC1
JENNY, M1
Turner, RC1
Dick, R1
Lee, EC1
Machina, T1
Marcus, R1
Levin, SR2
Sato, K1
Ishizuka, J1
Cooper, CW1
Chung, DH1
Tsuchiya, T1
Uchida, T1
Rajaraman, S1
Townsend, CM1
Thompson, JC1
Arnaout, MA1
Salti, I1
Koranyi, L1
Gero, L1
Balachandran, S1
Beierwaltes, WH1
Ice, RD1
Fajans, SS1
Ryo, UY1
Redmond, MJ1
Hetzel, KR1
Mosley, ST1
Feldstein, B1
Hazard, J1
Perlemuter, L1
Aderka, D1
Shaklai, M1
Doron, M1
Laron, Z1
Pinkhas, J1
De Vries, A1
Bricaire, H1
Luton, JP1
Wechsler, B1
Messing, B1
Halaby, G1
Agapova, EN1
Mikhalev, ID1
Lamas Barreiro, JM1
Arsensio Fierro, F1
Salas Puig, J1
Fernández Gutiérrez, I1
de Quirós, JF1
Imanaka, S2
Matsuda, S2
Ito, K2
Matsuoka, T2
Okada, Y2
Cohen, MS1
Bower, RH1
Fidler, SM1
Johnsonbaugh, RE1
Sode, J1
Pelkonen, R1
Taskinen, MR1
Schein, PS1
Vaisrub, S1
Hofeldt, FD1
Dippe, SE1
Karam, JH1
Blum, MR1
Forsham, PH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Phase 2/3 Multi-Center Study of SM-88 in Subjects With Pancreatic Cancer Whose Disease Has Progressed or Recurred[NCT03512756]Phase 2/Phase 3132 participants (Actual)Interventional2018-03-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phenytoin and Cancer of Pancreas

ArticleYear
[Localization of beta-Langerhans tumors secreting hypoglycemics].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1983

    Topics: Adenoma, Islet Cell; Angiography; Diazoxide; Humans; Insulin; Insulinoma; Intraoperative Period; Lap

1983

Trials

1 trial available for phenytoin and Cancer of Pancreas

ArticleYear
A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond.
    Cancer medicine, 2022, Volume: 11, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Humans; Methoxsalen; Pancreatic Neop

2022
A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond.
    Cancer medicine, 2022, Volume: 11, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Humans; Methoxsalen; Pancreatic Neop

2022
A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond.
    Cancer medicine, 2022, Volume: 11, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Humans; Methoxsalen; Pancreatic Neop

2022
A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond.
    Cancer medicine, 2022, Volume: 11, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Humans; Methoxsalen; Pancreatic Neop

2022

Other Studies

18 other studies available for phenytoin and Cancer of Pancreas

ArticleYear
[DILUTION HYPONATREMIA IN A CASE OF PANCREATIC CARCINOMA].
    Schweizerische medizinische Wochenschrift, 1964, Jun-27, Volume: 94

    Topics: Blood Chemical Analysis; Body Fluids; Chlorides; Cortisone; Drug Therapy; Ethanol; Geriatrics; Gluco

1964
[DILUTION HYPONATREMIA IN A CASE OF PANCREATIC CARCINOMA].
    Schweizerische medizinische Wochenschrift, 1964, Jun-27, Volume: 94

    Topics: Blood Chemical Analysis; Body Fluids; Chlorides; Cortisone; Drug Therapy; Ethanol; Geriatrics; Gluco

1964
[DILUTION HYPONATREMIA IN A CASE OF PANCREATIC CARCINOMA].
    Schweizerische medizinische Wochenschrift, 1964, Jun-27, Volume: 94

    Topics: Blood Chemical Analysis; Body Fluids; Chlorides; Cortisone; Drug Therapy; Ethanol; Geriatrics; Gluco

1964
[DILUTION HYPONATREMIA IN A CASE OF PANCREATIC CARCINOMA].
    Schweizerische medizinische Wochenschrift, 1964, Jun-27, Volume: 94

    Topics: Blood Chemical Analysis; Body Fluids; Chlorides; Cortisone; Drug Therapy; Ethanol; Geriatrics; Gluco

1964
Inhibition of glucagon secretion by diphenylhydantoin in a patient with glucagonoma.
    The Western journal of medicine, 1980, Volume: 132, Issue:4

    Topics: Blood Glucose; Female; Glucagon; Humans; Insulin; Middle Aged; Pancreatic Neoplasms; Phenytoin

1980
Inhibitory effect of calcium channel blockers on growth of pancreatic cancer cells.
    Pancreas, 1994, Volume: 9, Issue:2

    Topics: Calcium Channel Blockers; Cell Division; Humans; Pancreatic Neoplasms; Phenytoin; Tumor Cells, Cultu

1994
Letter: Phenytoin in benign insulinoma.
    Lancet (London, England), 1976, Apr-17, Volume: 1, Issue:7964

    Topics: Adenoma, Islet Cell; Adult; Antigens; Blood Glucose; Humans; Insulin; Insulin Secretion; Male; Pancr

1976
Influence of diphenylhydantoin on the effect of streptozotocin.
    British medical journal, 1979, Jan-13, Volume: 1, Issue:6156

    Topics: Adult; Apudoma; Drug Interactions; Humans; Insulin; Male; Neoplasm Metastasis; Pancreatic Neoplasms;

1979
Tissue distribution of 14C-, 125I-, and 131I-diphenylhydantoin in the toadfish, rat, and human with insulinomas.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1975, Volume: 16, Issue:8

    Topics: Adenoma, Islet Cell; Animals; Carbon Radioisotopes; Female; Fishes; Humans; In Vitro Techniques; Iod

1975
[Action of phenytoin on glycoregulation].
    La Nouvelle presse medicale, 1975, Sep-27, Volume: 4, Issue:31

    Topics: Adenoma, Islet Cell; Adolescent; Animals; Blood Pressure; Child; Child, Preschool; Depression, Chemi

1975
Letter: Phenytoin in metastatic insulinoma.
    JAMA, 1975, Dec-15, Volume: 234, Issue:11

    Topics: Adenoma, Islet Cell; Female; Humans; Middle Aged; Pancreatic Neoplasms; Phenytoin

1975
[Inappropriate secretion of insulin by an islet cell adenoma. Trial treatment with diphenylhydantoin].
    Annales de medecine interne, 1976, Volume: 127, Issue:5

    Topics: Adenoma, Islet Cell; Aged; Humans; Hypoglycemia; Male; Pancreatectomy; Pancreatic Neoplasms; Phenyto

1976
[Effectiveness of the use of diphenin in insuloma].
    Terapevticheskii arkhiv, 1977, Volume: 49, Issue:9

    Topics: Adenoma, Islet Cell; Adult; Drug Evaluation; Humans; Insulin Antagonists; Male; Pancreatic Neoplasms

1977
[Insulinoma, complex partial seizures and diphenylhydantoin].
    Revista clinica espanola, 1987, Volume: 181, Issue:1

    Topics: Adenoma, Islet Cell; Electroencephalography; Epilepsies, Partial; Female; Humans; Insulinoma; Middle

1987
[Studies on the medical treatment of non-operable insulinoma. Clinical usefulness of diphenylhydantoin-calcium antagonist].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1985, Volume: 74, Issue:5

    Topics: Adenoma, Islet Cell; Aged; Benzazepines; Diltiazem; Drug Therapy, Combination; Female; Humans; Insul

1985
Medical treatment for inoperable insulinoma: clinical usefulness of diphenylhydantoin and diltiazem.
    Japanese journal of clinical oncology, 1986, Volume: 16, Issue:1

    Topics: Adenoma, Islet Cell; Aged; Benzazepines; Blood Glucose; C-Peptide; Celiac Artery; Diltiazem; Female;

1986
Inhibition of insulin release by diphenylhydantoin and diazoxide in a patient with benign insulinoma.
    Lancet (London, England), 1973, Jan-06, Volume: 1, Issue:7793

    Topics: Adenoma, Islet Cell; Aged; Depression, Chemical; Diazoxide; Glucose; Humans; Insulin; Insulin Secret

1973
Effect of diphenylhydantoin on plasma-insulin in insulinoma.
    Lancet (London, England), 1973, Mar-17, Volume: 1, Issue:7803

    Topics: Adenoma; Adolescent; Adult; Carcinoma; Female; Humans; Insulin; Male; Pancreatic Neoplasms; Phenytoi

1973
Islet cell tumors: current concepts and management.
    Annals of internal medicine, 1973, Volume: 79, Issue:2

    Topics: Adenoma, Islet Cell; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Asparaginase; Child; Chil

1973
Diphenylhydantoin and insulin-secreting tumors.
    JAMA, 1973, Jan-29, Volume: 223, Issue:5

    Topics: Adenoma, Islet Cell; Humans; Hyperglycemia; Insulin; Insulin Antagonists; Insulin Secretion; Pancrea

1973
Effects of diphenylhydantoin upon glucose-induced insulin secretion in three patients with insulinoma.
    Diabetes, 1974, Volume: 23, Issue:3

    Topics: Adenoma, Islet Cell; Administration, Oral; Adult; Blood Glucose; Diazoxide; Drug Evaluation; Drug Th

1974