phenytoin has been researched along with Cancer of Lung in 34 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Agranulocytosis is a rare side effect of phenytoin treatment." | 7.68 | Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction? ( McClune, GL; Sharafuddin, MJ; Spanheimer, RG, 1991) |
| "Phenytoin is an anti-convulsant drug commonly used to prevent seizures in patients with cerebral metastases." | 3.73 | A case of phenytoin toxicity in a patient with advanced lung cancer. ( Jenkins, A, 2006) |
| "There are few reports about Stevens-Johnson syndrome, a bullous form of erythema multiforme, that can develop in patients treated with cranial irradiation and antiepileptic drugs, especially with phenytoin." | 3.72 | Toxic epidermal necrolysis after cranial radiotherapy and phenytoin treatment. ( Demirkesen, C; Koca, S; Oner Dincbas, F; Uzel, O; Yörük, S, 2004) |
| "Agranulocytosis is a rare side effect of phenytoin treatment." | 3.68 | Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction? ( McClune, GL; Sharafuddin, MJ; Spanheimer, RG, 1991) |
| " Following these findings, the influence of hydantoin on carcinogenesis was evaluated by using the model of urethane-induced lung adenomas in SWR mice." | 3.65 | Hydantoin immunosuppression and carcinogenesis. ( Levo, Y; Markowitz, O; Trainin, N, 1975) |
| " Concomitant use of erlotinib and the antiepileptic drug phenytoin, an inducer of CYP3A4, may result in a drug-drug interaction accompanied by changes in the blood concentrations of both drugs." | 1.43 | Drug interaction between erlotinib and phenytoin for brain metastases in a patient with nonsmall cell lung cancer. ( Homma, M; Kaburagi, T; Kurosawa, A; Ohgami, M, 2016) |
| "Brain metastases are a frequent finding in patients with advanced non-small cell lung cancer and concomitant administration of antiepileptic and chemotherapeutic drugs or epidermal growth factor receptor (EGFR) inhibitor is necessary in many cases." | 1.34 | Significant drug interaction: phenytoin toxicity due to erlotinib. ( Gabizon, A; Gipps, M; Grenader, T; Shavit, L, 2007) |
| "Oxazepam was stopped and a second series of dexamethasone pulse therapy was given." | 1.31 | Successful dexamethasone pulse therapy in a toxic epidermal necrolysis (TEN) patient featuring recurrent TEN to oxazepam. ( Beerthuizen, G; de Jong, MC; Jonkman, MF; Kardaun, SH; Nieuwenhuis, P; Schuttelaar, ML; Toth, GG; van der Meer, JB, 2001) |
| "The excess numbers of brain cancer were concentrated within 10 years of hospitalization (RR = 20." | 1.28 | Cancer among epileptic patients exposed to anticonvulsant drugs. ( Boice, JD; Fraumeni, JF; Jensen, JP; Olsen, JH, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (38.24) | 18.7374 |
| 1990's | 9 (26.47) | 18.2507 |
| 2000's | 5 (14.71) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Shyni, V | 1 |
| Leenaraj, DR | 1 |
| Ittyachan, R | 1 |
| Joseph, L | 1 |
| Sajan, D | 1 |
| Ahmed, I | 1 |
| Biswas, A | 1 |
| Krishnamurthy, S | 1 |
| Julka, PK | 1 |
| Vilas-Sueiro, A | 1 |
| Vázquez-Osorio, I | 1 |
| Suárez-Peñaranda, JM | 1 |
| Sánchez-Aguilar, D | 1 |
| Ohgami, M | 1 |
| Kaburagi, T | 1 |
| Kurosawa, A | 1 |
| Homma, M | 1 |
| Miranda, M | 1 |
| Kuester, G | 1 |
| Ríos, L | 1 |
| Basaez, E | 1 |
| Hazard, S | 1 |
| Aydoğan, K | 1 |
| Vatansever, S | 1 |
| Adim, SB | 1 |
| Saricaoglu, H | 1 |
| Pepe, C | 1 |
| Marchionni, C | 1 |
| Aguiar, D | 1 |
| Pazo, R | 1 |
| Durán, I | 1 |
| Terrasa, J | 1 |
| Arrivi, A | 1 |
| Manzano, H | 1 |
| Martín, J | 1 |
| Rifá, J | 1 |
| Oner Dincbas, F | 1 |
| Yörük, S | 1 |
| Demirkesen, C | 1 |
| Uzel, O | 1 |
| Koca, S | 1 |
| Jenkins, A | 1 |
| Grenader, T | 1 |
| Gipps, M | 1 |
| Shavit, L | 1 |
| Gabizon, A | 1 |
| Levo, Y | 3 |
| Jones, DH | 1 |
| Bleehen, NM | 1 |
| Workman, P | 1 |
| Walton, MI | 1 |
| Gabryś, K | 1 |
| Medraś, E | 1 |
| Kowalski, P | 1 |
| Gola, A | 1 |
| Sordillo, P | 1 |
| Matarese, RA | 1 |
| Novich, RK | 1 |
| Zabetakis, PM | 1 |
| Michelis, MF | 1 |
| Diwan, BA | 1 |
| Henneman, JR | 1 |
| Nims, RW | 1 |
| Rice, JM | 1 |
| Kawamura, KI | 1 |
| Grabowski, D | 1 |
| Weizer, K | 1 |
| Bukowski, R | 1 |
| Ganapathi, R | 1 |
| Recuenco, I | 1 |
| Espinosa, E | 1 |
| García, B | 1 |
| Carcas, A | 1 |
| Cockey, GH | 1 |
| Amann, ST | 1 |
| Reents, SB | 1 |
| Lynch, JW | 1 |
| Frangogiannis, NG | 1 |
| Boridy, I | 1 |
| Mazhar, M | 1 |
| Mathews, R | 1 |
| Gangopadhyay, S | 1 |
| Cate, T | 1 |
| Westhoven, GS | 1 |
| Fretzin, S | 1 |
| Lewis, C | 1 |
| van der Meer, JB | 1 |
| Schuttelaar, ML | 1 |
| Toth, GG | 1 |
| Kardaun, SH | 1 |
| Beerthuizen, G | 1 |
| de Jong, MC | 1 |
| Jonkman, MF | 1 |
| Nieuwenhuis, P | 1 |
| Markowitz, O | 1 |
| Trainin, N | 1 |
| Dil'man, VM | 1 |
| Bershteĭn, LM | 1 |
| Tsyrlina, EV | 1 |
| Bobrov, IuF | 1 |
| Kovaleva, IG | 1 |
| van der Graaf, WT | 1 |
| van Loon, AJ | 1 |
| Postmus, PE | 1 |
| Sleijfer, DT | 1 |
| Dyce, M | 1 |
| Sharif, SF | 1 |
| Whalen, GF | 1 |
| Sharafuddin, MJ | 1 |
| Spanheimer, RG | 1 |
| McClune, GL | 1 |
| Olsen, JH | 1 |
| Boice, JD | 1 |
| Jensen, JP | 1 |
| Fraumeni, JF | 1 |
| Keefe, M | 1 |
| Wakeel, RA | 1 |
| Dick, DC | 1 |
| Jones, SN | 1 |
| Stoker, DJ | 1 |
| Hayduk, K | 1 |
| Kaufmann, W | 1 |
| Williams, MH | 1 |
| Hendricks, GL | 1 |
| Barnes, WT | 1 |
| Hood, HL | 1 |
2 reviews available for phenytoin and Cancer of Lung
| Article | Year |
|---|---|
Empact syndrome: a case report and review of the literature.
Topics: Anticonvulsants; Brain Neoplasms; Drug Eruptions; Epilepsy; Humans; Lung Neoplasms; Male; Middle Age | 2010 |
[Schwartz-Bartter syndrome].
Topics: Adrenal Insufficiency; Carcinoma, Bronchogenic; Diagnosis, Differential; Hormones, Ectopic; Humans; | 1972 |
32 other studies available for phenytoin and Cancer of Lung
| Article | Year |
|---|---|
Spectroscopic, density functional theoretical study, molecular docking, and in vitro studies based on anticancer activity studies against A
Topics: A549 Cells; Antineoplastic Agents; Gold; Humans; In Vitro Techniques; Lung Neoplasms; Metal Nanopart | 2021 |
Toxic epidermal necrolysis in a patient receiving concurrent phenytoin and whole brain and thoracic radiotherapy.
Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Male; Middle Age | 2014 |
Erythema Multiforme Associated With Phenytoin and Cranial Radiation Therapy (EMPACT syndrome) in a Patient With Lung Cancer.
Topics: Cranial Irradiation; Erythema Multiforme; Humans; Lung Neoplasms; Male; Middle Aged; Phenytoin | 2016 |
Drug interaction between erlotinib and phenytoin for brain metastases in a patient with nonsmall cell lung cancer.
Topics: Brain; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 CYP1A2 Inducers; Cytochrome | 2016 |
Refractory nonconvulsive status epilepticus responsive to music as an add-on therapy: a second case.
Topics: Aged; Anticonvulsants; Brain Neoplasms; Humans; Lung Neoplasms; Male; Music Therapy; Phenytoin; Stat | 2010 |
A case of phenytoin-induced encephalopathy in a mathematician with Stage IV NSCLC.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Neurotoxicity Syndromes; Pheny | 2011 |
Toxic epidermal necrolysis in patients receiving anticonvulsants and cranial irradiation: a risk to consider.
Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cranial Irradiation; Humans; Lung | 2004 |
Toxic epidermal necrolysis after cranial radiotherapy and phenytoin treatment.
Topics: Aged; Anticonvulsants; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; C | 2004 |
A case of phenytoin toxicity in a patient with advanced lung cancer.
Topics: Anticonvulsants; Brain Neoplasms; Confusion; Fatal Outcome; Humans; Lung Neoplasms; Male; Middle Age | 2006 |
Significant drug interaction: phenytoin toxicity due to erlotinib.
Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Erlotinib Hydro | 2007 |
Immunologic alterations induced by phenytoin.
Topics: Adenoma; Animals; Antibody Formation; Humans; Lung Neoplasms; Mice; Phenytoin; T-Lymphocytes, Regula | 1982 |
The role of dexamethasone in the modification of misonidazole pharmacokinetics.
Topics: Adult; Aged; Dexamethasone; Drug Interactions; Female; Humans; Kinetics; Lung Neoplasms; Male; Metab | 1983 |
[Development of malignant lymphoma during anticonvulsant therapy].
Topics: Epilepsy; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Lymphoma; Male; Middle Aged; Phenytoin | 1983 |
Specific modalities of therapy for inappropriate antidiuretic hormone secretion.
Topics: Aged; Carbamazepine; Demeclocycline; Female; Glucocorticoids; Humans; Inappropriate ADH Syndrome; Lu | 1981 |
Tumor promotion by an anticonvulsant agent, phenytoin, in mouse liver: correlation with CYP2B induction.
Topics: Adenoma; Animals; Body Weight; Carcinogens; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; | 1993 |
Modulation of vinblastine cytotoxicity by dilantin (phenytoin) or the protein phosphatase inhibitor okadaic acid involves the potentiation of anti-mitotic effects and induction of apoptosis in human tumour cells.
Topics: Anticonvulsants; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Drug | 1996 |
Effect of dexamethasone on the decrease of serum phenytoin concentrations.
Topics: Anti-Inflammatory Agents; Anticonvulsants; Carcinoma, Squamous Cell; Dexamethasone; Humans; Lung Neo | 1995 |
Stevens-Johnson syndrome resulting from whole-brain radiation and phenytoin.
Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Squamous Cell; Chemoprevention; Cranial Irradiation; De | 1996 |
Cyclophosphamide in the treatment of toxic epidermal necrolysis.
Topics: Adult; Anticonvulsants; Body Surface Area; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cyclopho | 1996 |
A woman with lung cancer and exfoliative dermatitis. Phenytoin-induced pseudo-mycosis fungoides syndrome (PMFS).
Topics: Anticonvulsants; Dermatitis, Exfoliative; Female; Humans; Lung Neoplasms; Middle Aged; Mycosis Fungo | 1997 |
Successful dexamethasone pulse therapy in a toxic epidermal necrolysis (TEN) patient featuring recurrent TEN to oxazepam.
Topics: Anticonvulsants; Brain Neoplasms; Dexamethasone; Drug Therapy, Combination; Epidermis; Female; Gluco | 2001 |
Hydantoin immunosuppression and carcinogenesis.
Topics: Adenoma; Animals; Concanavalin A; Female; Immune Adherence Reaction; Immunity; Immunosuppression The | 1975 |
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C | 1975 |
[2 patients with brain metastases who became pregnant during phenytoin administration].
Topics: Abortion, Therapeutic; Adult; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Choriocarcinoma; Cont | 1992 |
Search for anti-metastatic therapy: effects of phenytoin on B16 melanoma metastasis.
Topics: Animals; Drug Screening Assays, Antitumor; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Pheny | 1992 |
Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction?
Topics: Agranulocytosis; Brain Neoplasms; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; | 1991 |
Cancer among epileptic patients exposed to anticonvulsant drugs.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Brain Neoplasms; Child; Child, Preschool; Denmark; | 1989 |
Death from metastatic, cutaneous, squamous cell carcinoma in autosomal recessive dystrophic epidermolysis bullosa despite permanent inpatient care.
Topics: Adult; Anti-Bacterial Agents; Carcinoma, Squamous Cell; Epidermolysis Bullosa; Fatty Acids; Female; | 1988 |
Radiology at your fingertips; lesions of the terminal phalanx.
Topics: Bone Cysts; Bone Diseases; Bone Neoplasms; Carcinoma, Bronchogenic; Chondroma; Epidermal Cyst; Finge | 1988 |
The protective effect of hydantoin treatment on carcinogenesis.
Topics: Adenoma; Animals; Lung Neoplasms; Mice; Mice, Inbred Strains; Phenytoin; Urethane | 1974 |
Special problems in respiratory diseases.
Topics: Adrenal Cortex Hormones; Aged; Aging; Anti-Bacterial Agents; Anticoagulants; Asthma; Bronchodilator | 1974 |
Seven-year "cure" of lung cancer with metastasis to the brain.
Topics: Adenocarcinoma; Brain Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Phe | 1972 |