Page last updated: 2024-10-21

phenytoin and Burns

phenytoin has been researched along with Burns in 15 studies

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
" Because of the alteration in these variables, wide intraindividual variation of pharmacokinetic parameters occurs depending upon the time since thermal injury and fluid resuscitation."2.44Influence of burns on pharmacokinetics and pharmacodynamics of drugs used in the care of burn patients. ( Blanchet, B; Jullien, V; Tod, M; Vinsonneau, C, 2008)
"Phenytoin appears to be an effective, low-cost and safe method for the treatment of partial-thickness skin graft donor sites, comparing very favourably with, and in some aspects superior to, occlusive dressings."1.29Topical phenytoin in the treatment of split-thickness skin autograft donor sites: a comparative study with polyurethane membrane drape and conventional dressing. ( Garg, S; Kumar, N; Singhvi, AM; Yadav, JK, 1993)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's2 (13.33)18.2507
2000's2 (13.33)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sayar, H1
Gergerlioglu, N1
Seringec, N1
Ozturk, P1
Bulbuloglu, E1
Karabay, G1
Gragnani, A1
Müller, BR1
Oliveira, AF1
Ferreira, LM1
Blanchet, B1
Jullien, V1
Vinsonneau, C1
Tod, M1
Meena, K1
Mohan, AV1
Sharath, B1
Somayaji, SN1
Bairy, KL1
Bhatia, A1
Prakash, S1
Chan, HL1
Perucca, E1
Bowdle, TA1
Neal, GD1
Levy, RH1
Heimbach, DM1
Yadav, JK1
Singhvi, AM1
Kumar, N1
Garg, S1
Fincham, RW1
Wiley, DE1
Schottelius, DD1
Ziegler, MG1
Morrissey, EC1
Marshall, LF1
Pugh, CB1
Houck, JC1
De Hesse, C1
Jacob, R1
Birch, AA1
Mitchell, GD1
Playford, GA1
Lang, CA1
Hall, KV1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Determining Drug Levels of Beta-lactam Antibiotics in Severe Burned Patients[NCT03335137]35 participants (Actual)Observational2014-05-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for phenytoin and Burns

ArticleYear
Burns and epilepsy--review and case report.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:2

    Topics: Adult; Anticonvulsants; Burns; Epilepsy; Female; Humans; Phenytoin

2015
Influence of burns on pharmacokinetics and pharmacodynamics of drugs used in the care of burn patients.
    Clinical pharmacokinetics, 2008, Volume: 47, Issue:10

    Topics: Analgesics; Anesthetics; Animals; Anti-Infective Agents; Anti-Ulcer Agents; Anticonvulsants; Burns;

2008
Topical phenytoin for wound healing.
    Dermatology online journal, 2004, Jul-15, Volume: 10, Issue:1

    Topics: Abscess; Administration, Topical; Burns; Collagenases; Connective Tissue; Diabetic Foot; Drug Evalua

2004
Plasma protein binding of phenytoin in health and disease: relevance to therapeutic drug monitoring.
    Therapeutic drug monitoring, 1980, Volume: 2, Issue:4

    Topics: Aging; Bilirubin; Blood Proteins; Burns; Disease; Drug Interactions; Fatty Acids, Nonesterified; Hum

1980

Trials

1 trial available for phenytoin and Burns

ArticleYear
Changes in serum potassium response to succinylcholine following trauma.
    JAMA, 1969, Oct-20, Volume: 210, Issue:3

    Topics: Burns; Carbon Dioxide; Fractures, Bone; Heart Arrest; Humans; Hyperkalemia; Injections, Intravenous;

1969

Other Studies

10 other studies available for phenytoin and Burns

ArticleYear
Comparison of efficacy of topical phenytoin with hypericin in second-degree burn wound healing: an experimental study in rats.
    Medical science monitor basic research, 2014, Apr-03, Volume: 20

    Topics: Administration, Topical; Animals; Anthracenes; Burns; Epidermis; Immunohistochemistry; Male; Perylen

2014
Effect of topical phenytoin on burn wound healing in rats.
    Indian journal of experimental biology, 2011, Volume: 49, Issue:1

    Topics: Administration, Topical; Animals; Anticonvulsants; Burns; Phenytoin; Rats; Rats, Wistar; Wound Heali

2011
Observations on drug-induced toxic epidermal necrolysis in Singapore.
    Journal of the American Academy of Dermatology, 1984, Volume: 10, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antipyrine; Barbiturates; Burns; Child; Diagnosis, Differenti

1984
Phenytoin pharmacokinetics in burned rats and plasma protein binding of phenytoin in burned patients.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:1

    Topics: Adult; Aged; Animals; Blood Proteins; Burns; Female; Humans; In Vitro Techniques; Kinetics; Male; Mi

1980
Topical phenytoin in the treatment of split-thickness skin autograft donor sites: a comparative study with polyurethane membrane drape and conventional dressing.
    Burns : journal of the International Society for Burn Injuries, 1993, Volume: 19, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Aged; Bandages; Burns; Child; Child, Preschool; Female;

1993
Use of phenytoin serum levels in a case of status epilepticus.
    Neurology, 1976, Volume: 26, Issue:9

    Topics: Adult; Burns; Epilepsy; Female; Humans; Oxacillin; Phenytoin

1976
Catecholamine and thyroid hormones in traumatic injury.
    Critical care medicine, 1990, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Brain Injuries; Burns; Catecholamines; Craniocerebral Trauma; Female; Humans; Mal

1990
Phenytoin and phenobarbital protein binding alterations in a uremic burn patient.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:3

    Topics: Burns; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Seizures; Serum Albumin

1987
The effect of ageing upon collagen metabolism.
    Symposia of the Society for Experimental Biology, 1967, Volume: 21

    Topics: Aging; Animals; Body Weight; Burns; Citrates; Collagen; Cycloheximide; Desoxycorticosterone; Glycine

1967
Encephalopathy complicating burn injuries in children. Two cases showing reversible EEG changes.
    Scandinavian journal of plastic and reconstructive surgery, 1968, Volume: 2, Issue:1

    Topics: Brain Diseases; Burns; Child; Child, Preschool; Electroencephalography; Female; Humans; Male; Neurol

1968