phenytoin has been researched along with Bradycardia in 53 studies
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate if phenytoin has the capacity to induce embryonic hypoxia mediated via adverse effects on the embryonic heart." | 7.69 | Initiation of phenytoin teratogenesis: pharmacologically induced embryonic bradycardia and arrhythmia resulting in hypoxia and possible free radical damage at reoxygenation. ( Azarbayjani, F; Danielsson, BR; Sköld, AC; Webster, WS, 1997) |
| "A severe poisoning with intravenous phenytoin in a newborn was treated with peritoneal dialysis in spite of its reported poor effectiveness, the drug being 90% protein-bound." | 7.68 | [Severe poisoning with intravenous phenytoin in the newborn. Value of peritoneal dialysis]. ( Devictor, D; Huault, G; Mersch, JM; Narcy, P; Taburet, AM; Zorza, G, 1990) |
| " Embryonic heart rate was also recorded on individual days after dosing days 9-16." | 5.31 | Phenytoin-induced cleft palate: evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier K+ channels resulting in hypoxia-reoxygenation damage. ( Azarbayjani, F; Danielsson, BR, 2001) |
| "The prodrug fosphenytoin (FOS) was recently introduced as an alternative to phenytoin (PTN) and has since become a first line therapy for status epilepticus." | 3.73 | Fosphenytoin may cause hemodynamically unstable bradydysrhythmias. ( Adams, BD; Buckley, NH; Kim, JY; Tipps, LB, 2006) |
| " Following phenytoin administration, the patient developed acute severe bradycardia, refractory to atropine and adrenaline." | 3.73 | Is phenytoin administration safe in a hypothermic child? ( Arora, R; Bhagat, H; Bithal, PK; Chouhan, RS, 2006) |
| "The aim of this study was to investigate if phenytoin has the capacity to induce embryonic hypoxia mediated via adverse effects on the embryonic heart." | 3.69 | Initiation of phenytoin teratogenesis: pharmacologically induced embryonic bradycardia and arrhythmia resulting in hypoxia and possible free radical damage at reoxygenation. ( Azarbayjani, F; Danielsson, BR; Sköld, AC; Webster, WS, 1997) |
| "A severe poisoning with intravenous phenytoin in a newborn was treated with peritoneal dialysis in spite of its reported poor effectiveness, the drug being 90% protein-bound." | 3.68 | [Severe poisoning with intravenous phenytoin in the newborn. Value of peritoneal dialysis]. ( Devictor, D; Huault, G; Mersch, JM; Narcy, P; Taburet, AM; Zorza, G, 1990) |
| "A number of drugs induced arrhythmias and these appeared to be related to either sodium channel blockade, which resulted in a double atrial beat for each ventricular beat, or I(Kr)/hERG blockade, which caused irregular atrial and ventricular beats." | 1.36 | The effect of drugs with ion channel-blocking activity on the early embryonic rat heart. ( Ababneh, D; Abela, D; Carlsson, K; Gavin, C; Khan, MK; Nilsson, MF; Ritchie, H; Webster, WS, 2010) |
| "Evidence suggests that untreated obstructive sleep apnea (OSA) can lead to hypertension, cardiovascular disease, and stroke." | 1.32 | Transient obstructive sleep apnea and asystole in association with presumed viral encephalopathy. ( Berger, HA; Dyken, ME; Yamada, T, 2003) |
| " Embryonic heart rate was also recorded on individual days after dosing days 9-16." | 1.31 | Phenytoin-induced cleft palate: evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier K+ channels resulting in hypoxia-reoxygenation damage. ( Azarbayjani, F; Danielsson, BR, 2001) |
| "Treatment with phenytoin or carbamazepine resulted in nearly complete resolution of symptoms in all five patients." | 1.28 | Bradycardia and syncope as manifestations of partial epilepsy. ( Constantin, L; Dagli, RD; Fincham, RW; Martins, JB, 1990) |
| "Type II (tonic) seizures are invariably associated with profound transient bradycardia, recovery from which begins about the time the tonic seizure phase ends." | 1.26 | Changes in heart rate associated with high-pressure convulsions in rodents. ( Beaver, RW; Brauer, RW; Fuquay, J, 1979) |
| "Nine of these had ventricular arrhythmia refractory to drugs." | 1.25 | Atrial pacing to control heart rate and rhythm in acute cardiac conditions. ( Friesen, WG, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (73.58) | 18.7374 |
| 1990's | 6 (11.32) | 18.2507 |
| 2000's | 5 (9.43) | 29.6817 |
| 2010's | 3 (5.66) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shihabuddin, BS | 1 |
| Herlopian, AS | 1 |
| Greenfield, LJ | 1 |
| Abela, D | 1 |
| Ritchie, H | 1 |
| Ababneh, D | 1 |
| Gavin, C | 1 |
| Nilsson, MF | 1 |
| Khan, MK | 1 |
| Carlsson, K | 1 |
| Webster, WS | 2 |
| Siebert, WJ | 1 |
| McGavigan, AD | 1 |
| Dyken, ME | 1 |
| Yamada, T | 1 |
| Berger, HA | 1 |
| ABIKO, Y | 1 |
| KONG, Y | 1 |
| HEYMAN, A | 1 |
| ENTMAN, ML | 1 |
| MCINTOSH, HD | 1 |
| CONN, RD | 1 |
| Adams, BD | 1 |
| Buckley, NH | 1 |
| Kim, JY | 1 |
| Tipps, LB | 1 |
| Bhagat, H | 1 |
| Bithal, PK | 1 |
| Chouhan, RS | 1 |
| Arora, R | 1 |
| Danielsson, C | 1 |
| Azarbayjani, F | 3 |
| Sköld, AC | 2 |
| Sjögren, N | 1 |
| Danielsson, BR | 3 |
| Wiriyathian, S | 1 |
| Kaojarern, S | 1 |
| Rosenfeld, CR | 1 |
| Korzets, Z | 1 |
| Ben-Chitrit, S | 1 |
| Bernheim, J | 1 |
| Farag, S | 1 |
| Watson, RD | 1 |
| Honeybourne, D | 1 |
| Taylor, PH | 1 |
| Gray, K | 1 |
| Bicknell, PG | 1 |
| Rees, JR | 1 |
| Beaver, RW | 1 |
| Brauer, RW | 1 |
| Fuquay, J | 1 |
| Barrillon, A | 1 |
| Grand, A | 1 |
| Surawicz, B | 1 |
| Gill, MA | 1 |
| Miscia, VF | 1 |
| Gourley, DR | 1 |
| Steinbach, K | 1 |
| Kennebäck, G | 1 |
| Bergfeldt, L | 1 |
| Narcy, P | 1 |
| Zorza, G | 1 |
| Taburet, AM | 1 |
| Mersch, JM | 1 |
| Devictor, D | 1 |
| Huault, G | 1 |
| Constantin, L | 1 |
| Martins, JB | 1 |
| Fincham, RW | 1 |
| Dagli, RD | 1 |
| Schollmeyer, P | 1 |
| Golochevskaia, VS | 1 |
| Hardewig, A | 1 |
| Diedrich, R | 1 |
| Hartl, O | 1 |
| Clodi, PH | 1 |
| Bender, F | 3 |
| Delius, W | 1 |
| Strubelt, O | 1 |
| Back, G | 1 |
| Uhl, E | 1 |
| Zetler, G | 1 |
| Hensel, G | 1 |
| Zoneraich, S | 1 |
| Zoneraich, O | 1 |
| Chung, EK | 1 |
| Awalt, CH | 1 |
| Vohra, JK | 1 |
| Adamska-Dyniewska, H | 1 |
| Lemberg, L | 1 |
| Castellanos, A | 1 |
| Arcebal, AG | 1 |
| Iyengar, RN | 1 |
| Patton, RD | 1 |
| Singer, DH | 1 |
| Ten Eick, RE | 1 |
| Marriott, HJ | 1 |
| Reynolds, EW | 1 |
| Khero, BA | 1 |
| Mullins, CB | 1 |
| Danzig, R | 1 |
| Huang, TF | 1 |
| Schmidt, E | 1 |
| Gradaus, D | 1 |
| Terry, G | 1 |
| Vellani, CW | 1 |
| Higgins, MR | 1 |
| Doig, A | 1 |
| Esser, H | 1 |
| Fricke, G | 1 |
| Blumsohn, D | 1 |
| Seabrook, M | 1 |
| Escher, DJ | 1 |
| Furman, S | 1 |
| Friesen, WG | 1 |
15 reviews available for phenytoin and Bradycardia
| Article | Year |
|---|---|
Requirement for cardiac telemetry during intravenous phenytoin infusion: guideline fact or guideline fiction?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Ca | 2013 |
Glossopharyngeal neuralgia with syncope.
Topics: Adult; Aged; Bradycardia; Carbamazepine; Female; Glossopharyngeal Nerve; Humans; Male; Middle Aged; | 1977 |
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects].
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glyc | 1976 |
The treatment of common cardiac arrhythmias.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine | 1976 |
[Cardiac arrhythmias. I. Pathogenesis and clinical significance].
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillat | 1971 |
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
[Modern treatment of cardiac arrhythmias].
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bradycardia; Cell Membrane Permeability; Digitali | 1971 |
Life-threatening arrhythmias.
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Female; Heart | 1973 |
Cardiac arrhythmias. Rationale of drug therapy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Bretylium Compounds; Cardiac Gl | 1973 |
Antiarrhythmic drugs.
Topics: Anesthesia; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digitalis Glycosides; Heart; | 1974 |
[Hydantoinal: new use of an old drug].
Topics: Animals; Arrhythmias, Cardiac; Biological Transport; Bradycardia; Dogs; Humans; Intestinal Absorptio | 1970 |
The treatment of arrhythmias following acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Bradycardia; Coronary Care Units; Digitalis Gly | 1971 |
Management of arrhythmias in acute myocardial infarction.
Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O | 1971 |
Aberrancy: electrophysiologic aspects.
Topics: Action Potentials; Adult; Animals; Arrhythmias, Cardiac; Bradycardia; Bundle-Branch Block; Dogs; Ele | 1971 |
Management of cardiac dysrhythmias complicating acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Bretylium Compound | 1968 |
38 other studies available for phenytoin and Bradycardia
| Article | Year |
|---|---|
Ictal asystole in epilepsy patients undergoing inpatient video-EEG monitoring.
Topics: Aged; Anticonvulsants; Bradycardia; Electroencephalography; Epilepsy, Temporal Lobe; Female; Heart A | 2014 |
The effect of drugs with ion channel-blocking activity on the early embryonic rat heart.
Topics: Abnormalities, Drug-Induced; Animals; Arrhythmias, Cardiac; Bradycardia; Embryo Culture Techniques; | 2010 |
Transient obstructive sleep apnea and asystole in association with presumed viral encephalopathy.
Topics: Adult; Bradycardia; Continuous Positive Airway Pressure; Encephalitis, Viral; Heart Arrest; Humans; | 2003 |
[Effect of diphenylhydantoin on the toxicity and heart action of strospeside in cats].
Topics: Anesthetics, General; Animals; Bradycardia; Cardiac Glycosides; Cats; Ethers; Heart; Pentobarbital; | 1962 |
GLOSSOPHARYNGEAL NEURALGIA ASSOCIATED WITH BRADYCARDIA, SYNCOPE, AND SEIZURES.
Topics: Atropine; Bradycardia; Drug Therapy; Electrocardiography; Geriatrics; Glossopharyngeal Nerve; Glosso | 1964 |
DIPHENYLHYDANTOIN SODIUM IN CARDIAC ARRHYTHMIAS.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Digitalis Glycosides; Drug T | 1965 |
Fosphenytoin may cause hemodynamically unstable bradydysrhythmias.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anticonvulsants | 2006 |
Is phenytoin administration safe in a hypothermic child?
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Atrioventricular Node; Atropine; Body Temperature; Bradycar | 2006 |
Polytherapy with hERG-blocking antiepileptic drugs: increased risk for embryonic cardiac arrhythmia and teratogenicity.
Topics: Animals; Anticonvulsants; Bradycardia; Dimethadione; Dose-Response Relationship, Drug; Drug Therapy, | 2007 |
Dilantin toxicity in a preterm infant: persistent bradycardia and lethargy.
Topics: Bradycardia; Dose-Response Relationship, Drug; Heart; Humans; Infant, Newborn; Infant, Premature, Di | 1982 |
Bradycardia as a presenting feature of late postpartum eclampsia.
Topics: Adult; Bradycardia; Drug Therapy, Combination; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedip | 1994 |
Symptomatic junctional bradycardia due to lithium intoxication in patient with previously normal electrocardiogram.
Topics: Aged; Bradycardia; Drug Synergism; Electrocardiography; Female; Humans; Lithium; Phenytoin | 1994 |
Initiation of phenytoin teratogenesis: pharmacologically induced embryonic bradycardia and arrhythmia resulting in hypoxia and possible free radical damage at reoxygenation.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cell Culture Techniques; Dose-Re | 1997 |
Phenytoin-induced cleft palate: evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier K+ channels resulting in hypoxia-reoxygenation damage.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bradycardia; Cleft Palate; Delayed Rectifier | 2001 |
Changes in heart rate associated with high-pressure convulsions in rodents.
Topics: Age Factors; Animals; Atmospheric Pressure; Atropine; Bradycardia; Female; Heart Rate; Mice; Phenoba | 1979 |
Arrhythmias and antiarrhythmic therapy in context.
Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Digitalis Glycosides; Hea | 1976 |
[Treatment of arrhythmia in general practice].
Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; H | 1975 |
[Bradyarrhythmias induced by antiepileptics increase frequency of epileptic seizures].
Topics: Aged; Bradycardia; Carbamazepine; Epilepsy; Humans; Male; Phenytoin | 1991 |
[Severe poisoning with intravenous phenytoin in the newborn. Value of peritoneal dialysis].
Topics: Biotransformation; Bradycardia; Humans; Infant, Newborn; Male; Peritoneal Dialysis; Phenytoin; Poiso | 1990 |
Bradycardia and syncope as manifestations of partial epilepsy.
Topics: Adult; Bradycardia; Carbamazepine; Electrocardiography; Electroencephalography; Epilepsy, Temporal L | 1990 |
[What is assured in the treatment of heart arrhythmia?].
Topics: Adrenergic beta-Antagonists; Ajmaline; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; C | 1972 |
[Therapy of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Caffeine; Cardiac Complexes, Prema | 1973 |
[Modern therapy of cardiac arrhythmias].
Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Brady | 1973 |
[Symposium on anti-arrhythmic drugs of the Swedish Society of Cardiology].
Topics: Adrenergic beta-Agonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digit | 1973 |
[Diphenylhydantoin therapy in heart rhythm disorders].
Topics: Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Digitalis Glycosides; Humans; Pheny | 1966 |
Cardiac output, heart rate, and blood pressure as influenced by equi-antiarrhythmic doses of eight antifibrillatory agents.
Topics: Aconitum; Ajmaline; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Bradycard | 1971 |
Medical treatment of cardiac arrhythmias.
Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrilla | 1971 |
Cardiovascular abnormalities following tricyclic antidepressant drug overdosage.
Topics: Acidosis; Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Bradycardia; Heart Rate; Humans | 1974 |
Beta-blocking agents in the management of cardiac arrhythmias.
Topics: Adult; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Cardiac Outp | 1971 |
Cardiac syncope due to glossopharyngeal neuralgia. Treatment with a transvenous pacemaker.
Topics: Adult; Bradycardia; Denervation; Female; Glossopharyngeal Nerve; Heart Arrest; Humans; Neuralgia; Pa | 1971 |
Treatment of arrhythmias associated with acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Humans; Isoproterenol; Lidocaine; | 1971 |
Study on diving bradycardia in toads and ducks.
Topics: Animals; Anura; Atropine; Bradycardia; Diving; Ducks; Heart Rate; Phenytoin; Propranolol; Quinidine; | 1969 |
[Drug therapy of arrhythmias].
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Female; Human | 1969 |
Bretylium tosylate in treatment of refractory ventricular arrhythmias complicating myocardial infarction.
Topics: Adult; Aged; Arrhythmias, Cardiac; Bradycardia; Bretylium Compounds; Electrocardiography; Female; Hu | 1970 |
[Therapy of the most important cardiac arrhythmias].
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Electric Countershock; Gluca | 1970 |
Oral diphenylhydantoin sodium and cardiovascular toxicity.
Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Humans; Phenytoin | 1970 |
Emergency treatment of cardiac arrhythmias. Emphasis on use of electrical pacing.
Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Electric Countershock; Electrocardiography; Electrodes; | 1970 |
Atrial pacing to control heart rate and rhythm in acute cardiac conditions.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Volume; Bradycardia; Cardiac Catheterization | 1971 |