phenytoin has been researched along with Bradyarrhythmia in 53 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate if phenytoin has the capacity to induce embryonic hypoxia mediated via adverse effects on the embryonic heart." | 7.69 | Initiation of phenytoin teratogenesis: pharmacologically induced embryonic bradycardia and arrhythmia resulting in hypoxia and possible free radical damage at reoxygenation. ( Azarbayjani, F; Danielsson, BR; Sköld, AC; Webster, WS, 1997) |
| "A severe poisoning with intravenous phenytoin in a newborn was treated with peritoneal dialysis in spite of its reported poor effectiveness, the drug being 90% protein-bound." | 7.68 | [Severe poisoning with intravenous phenytoin in the newborn. Value of peritoneal dialysis]. ( Devictor, D; Huault, G; Mersch, JM; Narcy, P; Taburet, AM; Zorza, G, 1990) |
| " Embryonic heart rate was also recorded on individual days after dosing days 9-16." | 5.31 | Phenytoin-induced cleft palate: evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier K+ channels resulting in hypoxia-reoxygenation damage. ( Azarbayjani, F; Danielsson, BR, 2001) |
| "The prodrug fosphenytoin (FOS) was recently introduced as an alternative to phenytoin (PTN) and has since become a first line therapy for status epilepticus." | 3.73 | Fosphenytoin may cause hemodynamically unstable bradydysrhythmias. ( Adams, BD; Buckley, NH; Kim, JY; Tipps, LB, 2006) |
| " Following phenytoin administration, the patient developed acute severe bradycardia, refractory to atropine and adrenaline." | 3.73 | Is phenytoin administration safe in a hypothermic child? ( Arora, R; Bhagat, H; Bithal, PK; Chouhan, RS, 2006) |
| "The aim of this study was to investigate if phenytoin has the capacity to induce embryonic hypoxia mediated via adverse effects on the embryonic heart." | 3.69 | Initiation of phenytoin teratogenesis: pharmacologically induced embryonic bradycardia and arrhythmia resulting in hypoxia and possible free radical damage at reoxygenation. ( Azarbayjani, F; Danielsson, BR; Sköld, AC; Webster, WS, 1997) |
| "A severe poisoning with intravenous phenytoin in a newborn was treated with peritoneal dialysis in spite of its reported poor effectiveness, the drug being 90% protein-bound." | 3.68 | [Severe poisoning with intravenous phenytoin in the newborn. Value of peritoneal dialysis]. ( Devictor, D; Huault, G; Mersch, JM; Narcy, P; Taburet, AM; Zorza, G, 1990) |
| "A number of drugs induced arrhythmias and these appeared to be related to either sodium channel blockade, which resulted in a double atrial beat for each ventricular beat, or I(Kr)/hERG blockade, which caused irregular atrial and ventricular beats." | 1.36 | The effect of drugs with ion channel-blocking activity on the early embryonic rat heart. ( Ababneh, D; Abela, D; Carlsson, K; Gavin, C; Khan, MK; Nilsson, MF; Ritchie, H; Webster, WS, 2010) |
| "Evidence suggests that untreated obstructive sleep apnea (OSA) can lead to hypertension, cardiovascular disease, and stroke." | 1.32 | Transient obstructive sleep apnea and asystole in association with presumed viral encephalopathy. ( Berger, HA; Dyken, ME; Yamada, T, 2003) |
| " Embryonic heart rate was also recorded on individual days after dosing days 9-16." | 1.31 | Phenytoin-induced cleft palate: evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier K+ channels resulting in hypoxia-reoxygenation damage. ( Azarbayjani, F; Danielsson, BR, 2001) |
| "Treatment with phenytoin or carbamazepine resulted in nearly complete resolution of symptoms in all five patients." | 1.28 | Bradycardia and syncope as manifestations of partial epilepsy. ( Constantin, L; Dagli, RD; Fincham, RW; Martins, JB, 1990) |
| "Type II (tonic) seizures are invariably associated with profound transient bradycardia, recovery from which begins about the time the tonic seizure phase ends." | 1.26 | Changes in heart rate associated with high-pressure convulsions in rodents. ( Beaver, RW; Brauer, RW; Fuquay, J, 1979) |
| "Nine of these had ventricular arrhythmia refractory to drugs." | 1.25 | Atrial pacing to control heart rate and rhythm in acute cardiac conditions. ( Friesen, WG, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (73.58) | 18.7374 |
| 1990's | 6 (11.32) | 18.2507 |
| 2000's | 5 (9.43) | 29.6817 |
| 2010's | 3 (5.66) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shihabuddin, BS | 1 |
| Herlopian, AS | 1 |
| Greenfield, LJ | 1 |
| Abela, D | 1 |
| Ritchie, H | 1 |
| Ababneh, D | 1 |
| Gavin, C | 1 |
| Nilsson, MF | 1 |
| Khan, MK | 1 |
| Carlsson, K | 1 |
| Webster, WS | 2 |
| Siebert, WJ | 1 |
| McGavigan, AD | 1 |
| Dyken, ME | 1 |
| Yamada, T | 1 |
| Berger, HA | 1 |
| ABIKO, Y | 1 |
| KONG, Y | 1 |
| HEYMAN, A | 1 |
| ENTMAN, ML | 1 |
| MCINTOSH, HD | 1 |
| CONN, RD | 1 |
| Adams, BD | 1 |
| Buckley, NH | 1 |
| Kim, JY | 1 |
| Tipps, LB | 1 |
| Bhagat, H | 1 |
| Bithal, PK | 1 |
| Chouhan, RS | 1 |
| Arora, R | 1 |
| Danielsson, C | 1 |
| Azarbayjani, F | 3 |
| Sköld, AC | 2 |
| Sjögren, N | 1 |
| Danielsson, BR | 3 |
| Wiriyathian, S | 1 |
| Kaojarern, S | 1 |
| Rosenfeld, CR | 1 |
| Korzets, Z | 1 |
| Ben-Chitrit, S | 1 |
| Bernheim, J | 1 |
| Farag, S | 1 |
| Watson, RD | 1 |
| Honeybourne, D | 1 |
| Taylor, PH | 1 |
| Gray, K | 1 |
| Bicknell, PG | 1 |
| Rees, JR | 1 |
| Beaver, RW | 1 |
| Brauer, RW | 1 |
| Fuquay, J | 1 |
| Barrillon, A | 1 |
| Grand, A | 1 |
| Surawicz, B | 1 |
| Gill, MA | 1 |
| Miscia, VF | 1 |
| Gourley, DR | 1 |
| Steinbach, K | 1 |
| Kennebäck, G | 1 |
| Bergfeldt, L | 1 |
| Narcy, P | 1 |
| Zorza, G | 1 |
| Taburet, AM | 1 |
| Mersch, JM | 1 |
| Devictor, D | 1 |
| Huault, G | 1 |
| Constantin, L | 1 |
| Martins, JB | 1 |
| Fincham, RW | 1 |
| Dagli, RD | 1 |
| Schollmeyer, P | 1 |
| Golochevskaia, VS | 1 |
| Hardewig, A | 1 |
| Diedrich, R | 1 |
| Hartl, O | 1 |
| Clodi, PH | 1 |
| Bender, F | 3 |
| Delius, W | 1 |
| Strubelt, O | 1 |
| Back, G | 1 |
| Uhl, E | 1 |
| Zetler, G | 1 |
| Hensel, G | 1 |
| Zoneraich, S | 1 |
| Zoneraich, O | 1 |
| Chung, EK | 1 |
| Awalt, CH | 1 |
| Vohra, JK | 1 |
| Adamska-Dyniewska, H | 1 |
| Lemberg, L | 1 |
| Castellanos, A | 1 |
| Arcebal, AG | 1 |
| Iyengar, RN | 1 |
| Patton, RD | 1 |
| Singer, DH | 1 |
| Ten Eick, RE | 1 |
| Marriott, HJ | 1 |
| Reynolds, EW | 1 |
| Khero, BA | 1 |
| Mullins, CB | 1 |
| Danzig, R | 1 |
| Huang, TF | 1 |
| Schmidt, E | 1 |
| Gradaus, D | 1 |
| Terry, G | 1 |
| Vellani, CW | 1 |
| Higgins, MR | 1 |
| Doig, A | 1 |
| Esser, H | 1 |
| Fricke, G | 1 |
| Blumsohn, D | 1 |
| Seabrook, M | 1 |
| Escher, DJ | 1 |
| Furman, S | 1 |
| Friesen, WG | 1 |
15 reviews available for phenytoin and Bradyarrhythmia
| Article | Year |
|---|---|
Requirement for cardiac telemetry during intravenous phenytoin infusion: guideline fact or guideline fiction?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Ca | 2013 |
Glossopharyngeal neuralgia with syncope.
Topics: Adult; Aged; Bradycardia; Carbamazepine; Female; Glossopharyngeal Nerve; Humans; Male; Middle Aged; | 1977 |
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects].
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glyc | 1976 |
The treatment of common cardiac arrhythmias.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine | 1976 |
[Cardiac arrhythmias. I. Pathogenesis and clinical significance].
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillat | 1971 |
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
[Modern treatment of cardiac arrhythmias].
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bradycardia; Cell Membrane Permeability; Digitali | 1971 |
Life-threatening arrhythmias.
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Female; Heart | 1973 |
Cardiac arrhythmias. Rationale of drug therapy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Bretylium Compounds; Cardiac Gl | 1973 |
Antiarrhythmic drugs.
Topics: Anesthesia; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digitalis Glycosides; Heart; | 1974 |
[Hydantoinal: new use of an old drug].
Topics: Animals; Arrhythmias, Cardiac; Biological Transport; Bradycardia; Dogs; Humans; Intestinal Absorptio | 1970 |
The treatment of arrhythmias following acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Bradycardia; Coronary Care Units; Digitalis Gly | 1971 |
Management of arrhythmias in acute myocardial infarction.
Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O | 1971 |
Aberrancy: electrophysiologic aspects.
Topics: Action Potentials; Adult; Animals; Arrhythmias, Cardiac; Bradycardia; Bundle-Branch Block; Dogs; Ele | 1971 |
Management of cardiac dysrhythmias complicating acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Bretylium Compound | 1968 |
38 other studies available for phenytoin and Bradyarrhythmia
| Article | Year |
|---|---|
Ictal asystole in epilepsy patients undergoing inpatient video-EEG monitoring.
Topics: Aged; Anticonvulsants; Bradycardia; Electroencephalography; Epilepsy, Temporal Lobe; Female; Heart A | 2014 |
The effect of drugs with ion channel-blocking activity on the early embryonic rat heart.
Topics: Abnormalities, Drug-Induced; Animals; Arrhythmias, Cardiac; Bradycardia; Embryo Culture Techniques; | 2010 |
Transient obstructive sleep apnea and asystole in association with presumed viral encephalopathy.
Topics: Adult; Bradycardia; Continuous Positive Airway Pressure; Encephalitis, Viral; Heart Arrest; Humans; | 2003 |
[Effect of diphenylhydantoin on the toxicity and heart action of strospeside in cats].
Topics: Anesthetics, General; Animals; Bradycardia; Cardiac Glycosides; Cats; Ethers; Heart; Pentobarbital; | 1962 |
GLOSSOPHARYNGEAL NEURALGIA ASSOCIATED WITH BRADYCARDIA, SYNCOPE, AND SEIZURES.
Topics: Atropine; Bradycardia; Drug Therapy; Electrocardiography; Geriatrics; Glossopharyngeal Nerve; Glosso | 1964 |
DIPHENYLHYDANTOIN SODIUM IN CARDIAC ARRHYTHMIAS.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Digitalis Glycosides; Drug T | 1965 |
Fosphenytoin may cause hemodynamically unstable bradydysrhythmias.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anticonvulsants | 2006 |
Is phenytoin administration safe in a hypothermic child?
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Atrioventricular Node; Atropine; Body Temperature; Bradycar | 2006 |
Polytherapy with hERG-blocking antiepileptic drugs: increased risk for embryonic cardiac arrhythmia and teratogenicity.
Topics: Animals; Anticonvulsants; Bradycardia; Dimethadione; Dose-Response Relationship, Drug; Drug Therapy, | 2007 |
Dilantin toxicity in a preterm infant: persistent bradycardia and lethargy.
Topics: Bradycardia; Dose-Response Relationship, Drug; Heart; Humans; Infant, Newborn; Infant, Premature, Di | 1982 |
Bradycardia as a presenting feature of late postpartum eclampsia.
Topics: Adult; Bradycardia; Drug Therapy, Combination; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedip | 1994 |
Symptomatic junctional bradycardia due to lithium intoxication in patient with previously normal electrocardiogram.
Topics: Aged; Bradycardia; Drug Synergism; Electrocardiography; Female; Humans; Lithium; Phenytoin | 1994 |
Initiation of phenytoin teratogenesis: pharmacologically induced embryonic bradycardia and arrhythmia resulting in hypoxia and possible free radical damage at reoxygenation.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cell Culture Techniques; Dose-Re | 1997 |
Phenytoin-induced cleft palate: evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier K+ channels resulting in hypoxia-reoxygenation damage.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bradycardia; Cleft Palate; Delayed Rectifier | 2001 |
Changes in heart rate associated with high-pressure convulsions in rodents.
Topics: Age Factors; Animals; Atmospheric Pressure; Atropine; Bradycardia; Female; Heart Rate; Mice; Phenoba | 1979 |
Arrhythmias and antiarrhythmic therapy in context.
Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Digitalis Glycosides; Hea | 1976 |
[Treatment of arrhythmia in general practice].
Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; H | 1975 |
[Bradyarrhythmias induced by antiepileptics increase frequency of epileptic seizures].
Topics: Aged; Bradycardia; Carbamazepine; Epilepsy; Humans; Male; Phenytoin | 1991 |
[Severe poisoning with intravenous phenytoin in the newborn. Value of peritoneal dialysis].
Topics: Biotransformation; Bradycardia; Humans; Infant, Newborn; Male; Peritoneal Dialysis; Phenytoin; Poiso | 1990 |
Bradycardia and syncope as manifestations of partial epilepsy.
Topics: Adult; Bradycardia; Carbamazepine; Electrocardiography; Electroencephalography; Epilepsy, Temporal L | 1990 |
[What is assured in the treatment of heart arrhythmia?].
Topics: Adrenergic beta-Antagonists; Ajmaline; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; C | 1972 |
[Therapy of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Caffeine; Cardiac Complexes, Prema | 1973 |
[Modern therapy of cardiac arrhythmias].
Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Brady | 1973 |
[Symposium on anti-arrhythmic drugs of the Swedish Society of Cardiology].
Topics: Adrenergic beta-Agonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digit | 1973 |
[Diphenylhydantoin therapy in heart rhythm disorders].
Topics: Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Digitalis Glycosides; Humans; Pheny | 1966 |
Cardiac output, heart rate, and blood pressure as influenced by equi-antiarrhythmic doses of eight antifibrillatory agents.
Topics: Aconitum; Ajmaline; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Bradycard | 1971 |
Medical treatment of cardiac arrhythmias.
Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrilla | 1971 |
Cardiovascular abnormalities following tricyclic antidepressant drug overdosage.
Topics: Acidosis; Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Bradycardia; Heart Rate; Humans | 1974 |
Beta-blocking agents in the management of cardiac arrhythmias.
Topics: Adult; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Cardiac Outp | 1971 |
Cardiac syncope due to glossopharyngeal neuralgia. Treatment with a transvenous pacemaker.
Topics: Adult; Bradycardia; Denervation; Female; Glossopharyngeal Nerve; Heart Arrest; Humans; Neuralgia; Pa | 1971 |
Treatment of arrhythmias associated with acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Humans; Isoproterenol; Lidocaine; | 1971 |
Study on diving bradycardia in toads and ducks.
Topics: Animals; Anura; Atropine; Bradycardia; Diving; Ducks; Heart Rate; Phenytoin; Propranolol; Quinidine; | 1969 |
[Drug therapy of arrhythmias].
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Female; Human | 1969 |
Bretylium tosylate in treatment of refractory ventricular arrhythmias complicating myocardial infarction.
Topics: Adult; Aged; Arrhythmias, Cardiac; Bradycardia; Bretylium Compounds; Electrocardiography; Female; Hu | 1970 |
[Therapy of the most important cardiac arrhythmias].
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Electric Countershock; Gluca | 1970 |
Oral diphenylhydantoin sodium and cardiovascular toxicity.
Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Humans; Phenytoin | 1970 |
Emergency treatment of cardiac arrhythmias. Emphasis on use of electrical pacing.
Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Electric Countershock; Electrocardiography; Electrodes; | 1970 |
Atrial pacing to control heart rate and rhythm in acute cardiac conditions.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Volume; Bradycardia; Cardiac Catheterization | 1971 |