phenytoin has been researched along with Benign Neoplasms in 29 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of phenytoin (PHT), buprenorphine (Bu), and Bu+PHT for the relief of cancer pain of various etiologies was evaluated in a randomized, double-blind study of 3 groups, each comprised of 25 patients." | 9.07 | Phenytoin as a coanalgesic in cancer pain. ( Kumar, M; Singh, G; Singh, GP; Yajnik, S, 1992) |
| "It was reported that phenytoin can prevent early post traumatic seizures." | 5.22 | Population Pharmacokinetics of Phenytoin Based on NONMEM in Patients with Intracranial Tumor During the First Week of Post-Craniotomy. ( Huang, YA; Lei, Z; Li, L; Li, ZD; Liu, M; Wan, JH, 2016) |
| "The efficacy of phenytoin (PHT), buprenorphine (Bu), and Bu+PHT for the relief of cancer pain of various etiologies was evaluated in a randomized, double-blind study of 3 groups, each comprised of 25 patients." | 5.07 | Phenytoin as a coanalgesic in cancer pain. ( Kumar, M; Singh, G; Singh, GP; Yajnik, S, 1992) |
| "This editorial was prompted by the published association of maternal diethylstilbestrol (DES) ingestion during pregnancy and subsequent development of vaginal adenocarcinoma among female offspring, and explores various factors involved in transplacental chemical carcinogenesis in humans." | 3.65 | Transplacental chemical carcinogenesis in man. ( Miller, RW, 1971) |
| "Free phenytoin was <1 mg/l on 132 occasions (51." | 2.72 | Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients. ( Beijnen, JH; Boogerd, W; Huitema, AD; Joerger, M; Schellens, JH; van der Sande, JJ, 2006) |
| "Cohorts of 3-6 pts with refractory cancer were treated with escalating doses of weekly IV bolus VRL (I -20." | 2.71 | Phase I trial of vinorelbine and diphenylhydantoin in patients with refractory carcinoma. ( Budd, GT; Bukowski, RM; Elson, P; Ganapathi, R; Hutson, TE; Mekhail, T; Olencki, T, 2004) |
| "Phenytoin has been causally implicated in three human cancers: lymphoma, myeloma and neuroblastoma, the latter specifically in the setting of foetal hydantoin syndrome." | 2.43 | Cancer risk in people with epilepsy: the role of antiepileptic drugs. ( Driever, PH; Sander, JW; Singh, G, 2005) |
| " VP-16 concentrations were measured in all plasma samples by high-performance liquid chromatography (HPLC) and electrochemical detection, and the results were analyzed with a pharmacokinetic data analysis system." | 1.29 | Pharmacokinetics of undiluted or diluted high-dose etoposide with or without busulfan administered to patients with hematologic malignancies. ( Bewermeier, P; Hossfeld, DK; Krüger, W; Mross, K; Stockschläder, M; Zander, A, 1994) |
| "The excess numbers of brain cancer were concentrated within 10 years of hospitalization (RR = 20." | 1.28 | Cancer among epileptic patients exposed to anticonvulsant drugs. ( Boice, JD; Fraumeni, JF; Jensen, JP; Olsen, JH, 1989) |
| "The mothers of children who developed cancer reported about 25% more illnesses during pregnancy than mothers of healthy control children." | 1.26 | Childhood cancer and drugs in pregnancy. ( Draper, GJ; Sanders, BM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (55.17) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Stega, J | 1 |
| Noel, MS | 1 |
| Vandell, AG | 1 |
| Stega, D | 1 |
| Del Priore, G | 1 |
| Hoffman, S | 1 |
| Li, ZD | 1 |
| Liu, M | 1 |
| Li, L | 1 |
| Wan, JH | 1 |
| Lei, Z | 1 |
| Huang, YA | 1 |
| MARX, GF | 1 |
| SCHEINBERG, L | 1 |
| ROMNEY, SL | 1 |
| Hutson, TE | 1 |
| Ganapathi, R | 1 |
| Elson, P | 1 |
| Mekhail, T | 1 |
| Olencki, T | 1 |
| Budd, GT | 1 |
| Bukowski, RM | 1 |
| Singh, G | 2 |
| Driever, PH | 1 |
| Sander, JW | 1 |
| Barron, MA | 1 |
| Doyle, J | 1 |
| Zlotkin, S | 1 |
| Joerger, M | 1 |
| Huitema, AD | 1 |
| Boogerd, W | 1 |
| van der Sande, JJ | 1 |
| Schellens, JH | 1 |
| Beijnen, JH | 1 |
| Hoang, BX | 1 |
| Levine, SA | 1 |
| Pham, P | 1 |
| Shaw, DG | 1 |
| Albengres, E | 1 |
| Tillement, JP | 1 |
| Mross, K | 1 |
| Bewermeier, P | 1 |
| Krüger, W | 1 |
| Stockschläder, M | 1 |
| Zander, A | 1 |
| Hossfeld, DK | 1 |
| White, SJ | 1 |
| McLean, AE | 1 |
| Howland, C | 1 |
| Sanders, BM | 1 |
| Draper, GJ | 1 |
| Miller, RW | 3 |
| Jusko, WJ | 1 |
| Gretch, M | 1 |
| Dil'man, VM | 1 |
| Bershteĭn, LM | 1 |
| Tsyrlina, EV | 1 |
| Bobrov, IuF | 1 |
| Kovaleva, IG | 1 |
| Bhatia, MT | 1 |
| Gregory, ER | 1 |
| Grossman, S | 1 |
| Sheidler, VR | 1 |
| Yajnik, S | 1 |
| Singh, GP | 1 |
| Kumar, M | 1 |
| Umstead, GS | 1 |
| Neumann, KH | 1 |
| Olsen, JH | 1 |
| Boice, JD | 1 |
| Jensen, JP | 1 |
| Fraumeni, JF | 2 |
| Tuttlebee, JW | 1 |
| Clemmesen, J | 1 |
| Fuglsang-Frederiksen, V | 1 |
| Plum, CM | 1 |
| Kopec, M | 1 |
| Yoshimasu, F | 1 |
| Kurland, LT | 1 |
| Elveback, LR | 1 |
4 reviews available for phenytoin and Benign Neoplasms
| Article | Year |
|---|---|
Cancer risk in people with epilepsy: the role of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neoplasms; Phenobarbital; Phenytoin; Rats | 2005 |
Plasma and tissue protein binding of drugs in pharmacokinetics.
Topics: Adrenal Cortex Hormones; Age Factors; Aging; Albumins; Animals; Anti-Bacterial Agents; Antibodies; A | 1976 |
Drug-induced cancer.
Topics: Alkylating Agents; Animals; Carcinogens; Diethylstilbestrol; Drug-Related Side Effects and Adverse R | 1972 |
[New data evidencing the role of antigenic stimulation in the pathogenesis of neoplasms of the lymphatic and plasmocytic systems. I. Can drug-induced hypersensitivity reactions lead to neoplastic proliferation in the lymphatic system?].
Topics: Adjuvants, Immunologic; Antigens, Neoplasm; Antistreptolysin; Diagnosis, Differential; Drug Hypersen | 1972 |
5 trials available for phenytoin and Benign Neoplasms
| Article | Year |
|---|---|
A first-in-human study of the novel metabolism-based anti-cancer agent SM-88 in subjects with advanced metastatic cancer.
Topics: Aged; alpha-Methyltyrosine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; E | 2020 |
Population Pharmacokinetics of Phenytoin Based on NONMEM in Patients with Intracranial Tumor During the First Week of Post-Craniotomy.
Topics: Adult; Aged; Anticonvulsants; Asian People; Craniotomy; Cytochrome P-450 CYP2C19; Cytochrome P-450 C | 2016 |
Phase I trial of vinorelbine and diphenylhydantoin in patients with refractory carcinoma.
Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Phytogenic; Cell Line, Tu | 2004 |
Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Algorithms; Analysis of Variance; Antineoplast | 2006 |
Phenytoin as a coanalgesic in cancer pain.
Topics: Adult; Buprenorphine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neoplasms; Pain; | 1992 |
20 other studies available for phenytoin and Benign Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
ANESTHETIC MANAGEMENT OF THE PARTURIENT WITH INTRACRANIAL TUMOR.
Topics: Anesthesia; Anesthesia, Endotracheal; Anesthesia, Spinal; Anesthetics; Angiography; Brain Neoplasms; | 1964 |
Vitamin K deficiency in children pre-bone marrow transplantation.
Topics: Adolescent; Anticonvulsants; Bone Marrow Transplantation; Child; Child, Preschool; Drug Antagonism; | 2006 |
Hypothesis of the cause and development of neoplasms.
Topics: Anti-Infective Agents; Anticonvulsants; Antineoplastic Agents; Artemisia; Artemisinins; Cell Death; | 2007 |
Phenytoin in pregnancy: a review of the reported risks.
Topics: Abnormalities, Drug-Induced; Blood Coagulation Disorders; Epilepsy; Female; Humans; Infant; Infant, | 1983 |
Pharmacokinetics of undiluted or diluted high-dose etoposide with or without busulfan administered to patients with hematologic malignancies.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Chromatography, | 1994 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; | 1977 |
Anticonvulsant drugs and cancer. A cohort study in patients with severe epilepsy.
Topics: Adolescent; Adult; Brain Neoplasms; Child; England; Epilepsy; Female; Follow-Up Studies; Humans; Mal | 1979 |
Childhood cancer and drugs in pregnancy.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Fetus; Humans; Infant; Infant, Newborn | 1979 |
Advances in understanding causes of childhood cancer.
Topics: Asbestos; Child; Diethylstilbestrol; Drug-Related Side Effects and Adverse Reactions; Environmental | 1979 |
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C | 1975 |
Anticonvulsant alone in the relief of cancer pain.
Topics: Adult; Aged; Anticonvulsants; Female; Humans; Male; Middle Aged; Neoplasms; Pain, Intractable; Palli | 1992 |
Grand mal seizures associated with high-dose intravenous morphine infusions: incidence and possible etiology.
Topics: Adult; Aged; Epilepsy, Tonic-Clonic; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Morp | 1992 |
Correlation of free phenytoin to serum albumin in cancer patients.
Topics: Female; Humans; Male; Middle Aged; Neoplasms; Phenytoin; Serum Albumin | 1990 |
Cancer among epileptic patients exposed to anticonvulsant drugs.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Brain Neoplasms; Child; Child, Preschool; Denmark; | 1989 |
Free triiodothyronine in serum in relation to thyroid function.
Topics: Adult; Female; Humans; Male; Middle Aged; Neoplasms; Phenytoin; Pregnancy; Radioimmunoassay; Thyroid | 1985 |
Are anticonvulsants oncogenic?
Topics: Anticonvulsants; Denmark; Epilepsy; Female; Humans; Male; Neoplasms; Phenobarbital; Phenytoin; Primi | 1974 |
Transplacental chemical carcinogenesis in man.
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Chloramphenicol; Diethylstilbestrol; Female; Foll | 1971 |
Tic douloureux in Rochester, Minnesota, 1945-1969.
Topics: Adult; Age Factors; Aged; Analgesics; Carbamazepine; Ethanol; Female; Follow-Up Studies; Humans; Hyp | 1972 |
Immune mechanisms in cancer.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Antigens, Neoplasm; Humans; Immunity, Cellu | 1973 |