Page last updated: 2024-10-21

phenytoin and Bed Sores

phenytoin has been researched along with Bed Sores in 15 studies

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of topical phenytoin solution in treating pressure ulcers among patients with spinal cord disorders and to evaluate the systemic absorption of topical phenytoin."9.12Topical phenytoin solution for treating pressure ulcers: a prospective, randomized, double-blind clinical trial. ( Chandy, SJ; Durai, S; George, J; Margaret Shanti, FX; Mathew, BS; Neelakantan, N; Subbanna, PK; Suresh, R; Tharion, G, 2007)
" In this study we compared the therapeutic effects of HD on pressure ulcer healing with two other topical applications, phenytoin cream (PC) and simple dressing (SD)."9.11A randomized clinical trial comparing hydrocolloid, phenytoin and simple dressings for the treatment of pressure ulcers [ISRCTN33429693]. ( Hollisaz, MT; Khedmat, H; Yari, F, 2004)
"To assess the effects of topical phenytoin on the rate of healing of pressure ulcers of any grade, in any care setting."8.95Topical phenytoin for treating pressure ulcers. ( Cai, H; Guo, TK; Hao, XY; Jiang, L; Li, HL; Liu, R; Shen, YF; Su, H, 2017)
"To evaluate the efficacy of topical phenytoin solution in treating pressure ulcers among patients with spinal cord disorders and to evaluate the systemic absorption of topical phenytoin."5.12Topical phenytoin solution for treating pressure ulcers: a prospective, randomized, double-blind clinical trial. ( Chandy, SJ; Durai, S; George, J; Margaret Shanti, FX; Mathew, BS; Neelakantan, N; Subbanna, PK; Suresh, R; Tharion, G, 2007)
" In this study we compared the therapeutic effects of HD on pressure ulcer healing with two other topical applications, phenytoin cream (PC) and simple dressing (SD)."5.11A randomized clinical trial comparing hydrocolloid, phenytoin and simple dressings for the treatment of pressure ulcers [ISRCTN33429693]. ( Hollisaz, MT; Khedmat, H; Yari, F, 2004)
"To assess the effects of topical phenytoin on the rate of healing of pressure ulcers of any grade, in any care setting."4.95Topical phenytoin for treating pressure ulcers. ( Cai, H; Guo, TK; Hao, XY; Jiang, L; Li, HL; Liu, R; Shen, YF; Su, H, 2017)
" Routine use of topical phenytoin, silver preparations, or growth factors in therapy of pressure ulcers cannot be recommended until more data from rigorously designed studies are available."4.86Update on pressure ulcer management and deep tissue injury. ( Mao, CL; Pasko, MT; Rivet, AJ; Sidora, T, 2010)
"Fifteen PHT-treated decubitus ulcer patients healed in 1-3 weeks (one graft) versus 6-8 weeks (five grafts) in the control group."2.66Preliminary experience with topical phenytoin in wound healing in a war zone. ( el Zayat, SG, 1989)
"Dressings are widely used to treat pressure ulcers and promote healing, and there are many options to choose from including alginate, hydrocolloid and protease-modulating dressings."2.55Dressings and topical agents for treating pressure ulcers. ( Dumville, JC; Norman, G; Soares, MO; Stubbs, N; Westby, MJ, 2017)
"Pressure ulcers are more likely in people with reduced mobility and poor skin condition, such as older people or those with vascular disease."2.47Pressure ulcers. ( Reddy, M, 2011)
"Pressure ulcers are more likely in people with reduced mobility and poor skin condition, such as older people or those with vascular disease."2.44Pressure ulcers. ( Cullum, N; Petherick, E, 2008)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's1 (6.67)18.2507
2000's5 (33.33)29.6817
2010's6 (40.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Sheir, MM1
Nasra, MMA1
Abdallah, OY1
Inchingolo, F1
Vermesan, D1
Inchingolo, AD1
Malcangi, G1
Santacroce, L1
Scacco, S1
Benagiano, V1
Girolamo, F1
Cagiano, R1
Caprio, M1
Longo, L1
Abbinante, A1
Inchingolo, AM1
Dipalma, G1
Tarullo, A1
Tattoli, M1
Westby, MJ1
Dumville, JC1
Soares, MO1
Stubbs, N1
Norman, G1
Hao, XY1
Li, HL1
Su, H1
Cai, H1
Guo, TK1
Liu, R1
Jiang, L1
Shen, YF1
Cullum, N1
Petherick, E1
Mao, CL1
Rivet, AJ1
Sidora, T1
Pasko, MT1
Reddy, M1
Nicolas, B1
Moiziard, AS1
Barrois, B1
Colin, D1
Michel, JM1
Passadori, Y1
Ribinik, P1
Hollisaz, MT1
Khedmat, H1
Yari, F1
Arinzon, Z1
Zeilig, G1
Berner, YN1
Adunsky, A1
Subbanna, PK1
Margaret Shanti, FX1
George, J1
Tharion, G1
Neelakantan, N1
Durai, S1
Chandy, SJ1
Mathew, BS1
Suresh, R1
Johnson, TJ1
Rhodes, RS1
Heyneman, CA1
Culbertson, VL1
Wilson, SE1
Phatak, HM1
el Zayat, SG1
Cuzzell, JZ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Effects of Two Different Wound Dressing on the Pressure Injury Patients in Long-term Care Institutions[NCT05667831]160 participants (Actual)Interventional2021-08-13Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for phenytoin and Bed Sores

ArticleYear
Dressings and topical agents for treating pressure ulcers.
    The Cochrane database of systematic reviews, 2017, 06-22, Volume: 6

    Topics: Alginates; Bandages; Bandages, Hydrocolloid; Collagenases; Dermatologic Agents; Egg White; Gels; Glu

2017
Topical phenytoin for treating pressure ulcers.
    The Cochrane database of systematic reviews, 2017, 02-22, Volume: 2

    Topics: Administration, Topical; Anti-Bacterial Agents; Bandages; Bandages, Hydrocolloid; Dermatologic Agent

2017
Pressure ulcers.
    BMJ clinical evidence, 2008, Mar-19, Volume: 2008

    Topics: Animals; Bandages; Beds; Humans; Low-Level Light Therapy; Negative-Pressure Wound Therapy; Phenytoin

2008
Update on pressure ulcer management and deep tissue injury.
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:2

    Topics: Administration, Cutaneous; Aged; Animals; Clinical Trials as Topic; Humans; Intercellular Signaling

2010
Pressure ulcers.
    BMJ clinical evidence, 2011, Apr-28, Volume: 2011

    Topics: Anticonvulsants; Bandages; Bedding and Linens; Beds; Debridement; Humans; Low-Level Light Therapy; N

2011
Which medical devices and/or local drug should be curatively used, as of 2012, for PU patients? How can granulation and epidermidalization be promoted? Developing French guidelines for clinical practice.
    Annals of physical and rehabilitation medicine, 2012, Volume: 55, Issue:7

    Topics: Bandages; Humans; Phenytoin; Phototherapy; Practice Guidelines as Topic; Pressure Ulcer; Wound Heali

2012

Trials

5 trials available for phenytoin and Bed Sores

ArticleYear
Bedsores successfully treated with topical phenytoin.
    Acta bio-medica : Atenei Parmensis, 2017, 04-28, Volume: 88, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Dermatologic Agents; Female; Humans; Male; Middle

2017
A randomized clinical trial comparing hydrocolloid, phenytoin and simple dressings for the treatment of pressure ulcers [ISRCTN33429693].
    BMC dermatology, 2004, Dec-15, Volume: 4, Issue:1

    Topics: Administration, Topical; Adult; Colloids; Humans; Male; Occlusive Dressings; Phenytoin; Pressure Ulc

2004
Topical phenytoin solution for treating pressure ulcers: a prospective, randomized, double-blind clinical trial.
    Spinal cord, 2007, Volume: 45, Issue:11

    Topics: Administration, Topical; Adolescent; Adult; Anticonvulsants; Child; Double-Blind Method; Female; Hum

2007
Topical phenytoin treatment of stage II decubitus ulcers in the elderly.
    The Annals of pharmacotherapy, 2001, Volume: 35, Issue:6

    Topics: Administration, Topical; Aged; Anticonvulsants; Female; Health Services for the Aged; Humans; Male;

2001
Preliminary experience with topical phenytoin in wound healing in a war zone.
    Military medicine, 1989, Volume: 154, Issue:4

    Topics: Administration, Topical; Adult; Humans; Iraq; Military Personnel; Phenytoin; Pressure Ulcer; Warfare

1989

Other Studies

4 other studies available for phenytoin and Bed Sores

ArticleYear
Phenytoin-loaded bioactive nanoparticles for the treatment of diabetic pressure ulcers: formulation and in vitro/in vivo evaluation.
    Drug delivery and translational research, 2022, Volume: 12, Issue:12

    Topics: Animals; Chitosan; Collagen; Diabetes Mellitus, Experimental; Nanoparticles; Phenytoin; Pressure Ulc

2022
Antiepileptic drug use and the occurrence of pressure ulcers among bedridden institutionalized elderly patients: a retrospective chart review.
    The American journal of geriatric pharmacotherapy, 2005, Volume: 3, Issue:3

    Topics: Activities of Daily Living; Administration, Oral; Aged; Anticonvulsants; Female; Humans; Institution

2005
Use of topical phenytoin for wound care.
    South Dakota journal of medicine, 1998, Volume: 51, Issue:10

    Topics: Administration, Topical; Humans; Phenytoin; Polyarteritis Nodosa; Pressure Ulcer; Wound Healing

1998
Wound care forum: Readers' remedies for pressure sores.
    The American journal of nursing, 1986, Volume: 86, Issue:8

    Topics: Administration, Topical; Aloe; Fats; Hot Temperature; Humans; Occlusive Dressings; Petrolatum; Pheny

1986