phenytoin and Ataxia
phenytoin has been researched along with Ataxia in 89 studies
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebellar ataxia is present in 40% of patients with epilepsy and chronic exposure to phenytoin." | 7.88 | Phenytoin-related ataxia in patients with epilepsy: clinical and radiological characteristics. ( Aeschlimann, DP; Aeschlimann, PC; Dennis, GJ; Grünewald, RA; Hadjivassiliou, M; Hoggard, N; Howell, SJ; Reuber, M; Shanmugarajah, PD, 2018) |
| "Acute ataxia is commonly the chief complaint among patients visiting the emergency department (ED)." | 5.72 | A Phenytoin-Induced Ataxia Mimicking a Stroke. ( Urushidani, S, 2022) |
| "We present the case of a 77 year old man who had been treated for twenty years with phenytoin for partial crises secondary to a left frontal hematoma." | 4.80 | [Acute phenytoin poisoning secondary to an interaction with ticlopidine]. ( López-Ariztegui, N; Martín, M; Nevado, C; Ochoà, M; Sánchez-Migallón, MJ, 1998) |
| "Cerebellar ataxia is present in 40% of patients with epilepsy and chronic exposure to phenytoin." | 3.88 | Phenytoin-related ataxia in patients with epilepsy: clinical and radiological characteristics. ( Aeschlimann, DP; Aeschlimann, PC; Dennis, GJ; Grünewald, RA; Hadjivassiliou, M; Hoggard, N; Howell, SJ; Reuber, M; Shanmugarajah, PD, 2018) |
| " When fluconazole, a potent inhibitor of CYP2C9, was added to the treatment regimen, the patient developed ataxia, tremor, fatigue, slurred speech and somnolence, indicating phenytoin intoxication." | 3.76 | Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9. ( Bergman, U; Bertilsson, L; Engström Hellgren, K; Helldén, A; Masquelier, M; Nilsson Remahl, I; Odar-Cederlöf, I; Ramsjö, M, 2010) |
| "Colchicine poisoning is an uncommon, but potentially life-threatening, toxicologic emergency." | 3.74 | Acute colchicine intoxication in a child: a case report. ( Biçer, S; Ctak, A; Karaböcüoğlu, M; Soysal, DD; Uçsel, R; Uzel, N, 2007) |
| "Aromatic and heterocyclic esters of 1-methyl-4-piperidinol and 1,4-dimethyl-4-piperidinol and aromatic esters of (dialkylamino)alkanols were prepared and evaluated for antiepileptic activity by the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole seizure threshold (scMet) assays and for minimal central neurotoxicity by the rotorod ataxia test." | 3.67 | Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters. ( Creveling, CR; Daly, JW; Hollingsworth, EB; Lewandowski, G; Waters, JA, 1986) |
| "A young epileptic presented with spasticity as well as ataxia, diplopia and nystagmus; his serum phenytoin level was very high." | 3.66 | Spasticity due to phenytoin toxicity. ( Stark, RJ, 1979) |
| "Two patients with intractable epilepsy who had been treated with various combinations of anticonvulsant drugs developed phenytoin encephalopathy." | 3.65 | Choreo-athetosis and encephalopathy induced by phenytoin. ( McLellan, DL; Swash, M, 1974) |
| "Clinical signs of ataxia can persist without radiological evidence of cerebellar atrophy, and cerebellar atrophy is seen without any clinical evidence of cerebellar dysfunction." | 2.82 | Phenytoin and damage to the cerebellum - a systematic review of published cases. ( Bradberry, SM; Day, R; Ferner, R, 2022) |
| "Acute ataxia is commonly the chief complaint among patients visiting the emergency department (ED)." | 1.72 | A Phenytoin-Induced Ataxia Mimicking a Stroke. ( Urushidani, S, 2022) |
| "This case suggests that dysphagia related to phenytoin-induced lymphoid hypertrophy may be treated by phenytoin discontinuation followed by a sufficient amount of time to allow symptom resolution rather than by prompt surgery." | 1.46 | Velopharyngeal Incoordination Caused by Phenytoin-Induced Toxicity. ( Hwang, CH, 2017) |
| "1 microg/mL when fluvoxamine was coadministered, although the daily dosage of phenytoin and other drugs had not changed." | 1.31 | Phenytoin intoxication induced by fluvoxamine. ( Higuchi, S; Ieiri, I; Kojima, K; Mamiya, K; Ninomiya, H; Tashiro, N; Yukawa, E, 2001) |
| "In rats aged 18 days or less ataxia of hindlimbs was also marked." | 1.27 | Convulsant action of diphenylhydantoin overdose in young rats. ( Lisková-Bernásková, K; Mares, P; Mudrochová, M, 1987) |
Research
Studies (89)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (77.53) | 18.7374 |
| 1990's | 6 (6.74) | 18.2507 |
| 2000's | 4 (4.49) | 29.6817 |
| 2010's | 8 (8.99) | 24.3611 |
| 2020's | 2 (2.25) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Pavia, MR | 3 |
| Lobbestael, SJ | 3 |
| Taylor, CP | 3 |
| Hershenson, FM | 2 |
| Miskell, DL | 1 |
| Waters, JA | 1 |
| Hollingsworth, EB | 1 |
| Daly, JW | 1 |
| Lewandowski, G | 1 |
| Creveling, CR | 1 |
| Ferner, R | 1 |
| Day, R | 1 |
| Bradberry, SM | 1 |
| Urushidani, S | 1 |
| Shanmugarajah, PD | 1 |
| Hoggard, N | 1 |
| Aeschlimann, DP | 1 |
| Aeschlimann, PC | 1 |
| Dennis, GJ | 1 |
| Howell, SJ | 1 |
| Reuber, M | 1 |
| Grünewald, RA | 1 |
| Hadjivassiliou, M | 1 |
| Watters, M | 1 |
| Wilson, H | 1 |
| Everitt, P | 1 |
| Burns, JM | 1 |
| Marino, A | 1 |
| Manno, M | 1 |
| Rhyee, S | 1 |
| Boyer, EW | 1 |
| Zappia, CP | 1 |
| Piccirillo, B | 1 |
| Hwang, CH | 1 |
| Helldén, A | 1 |
| Bergman, U | 1 |
| Engström Hellgren, K | 1 |
| Masquelier, M | 1 |
| Nilsson Remahl, I | 1 |
| Odar-Cederlöf, I | 1 |
| Ramsjö, M | 1 |
| Bertilsson, L | 1 |
| Shimizu, T | 1 |
| Ambrose, T | 1 |
| Chandra, N | 1 |
| DAVIS, MA | 1 |
| WINTHROP, SO | 1 |
| THOMAS, RA | 1 |
| HERR, F | 1 |
| CHAREST, MP | 1 |
| GAUDRY, R | 1 |
| KUTT, H | 7 |
| WINTERS, W | 3 |
| KOKENGE, R | 2 |
| MCDOWELL, F | 5 |
| SCHERMAN, R | 1 |
| KISHI, Y | 1 |
| MANMARU, S | 1 |
| FUKUI, S | 1 |
| AOKI, Y | 1 |
| SNYDER, CH | 1 |
| Biçer, S | 1 |
| Soysal, DD | 1 |
| Ctak, A | 1 |
| Uçsel, R | 1 |
| Karaböcüoğlu, M | 1 |
| Uzel, N | 1 |
| Hansen, OE | 2 |
| Lund, MA | 1 |
| Perez del Cerro, M | 1 |
| Snider, RS | 1 |
| Frantzen, E | 1 |
| Hansen, JM | 1 |
| Kristensen, M | 1 |
| Berger, JR | 1 |
| Kovacs, AG | 1 |
| Gore, JM | 1 |
| Haffajee, CI | 1 |
| Alpert, JS | 1 |
| Skillrud, DM | 1 |
| Goldstein, NP | 1 |
| Solomon, JG | 1 |
| Ikeda, H | 1 |
| Vincent, FM | 1 |
| Garson, A | 1 |
| Kugler, JD | 1 |
| Gillette, PC | 1 |
| Simonelli, A | 1 |
| McNamara, DG | 1 |
| Abe, K | 1 |
| Okano, M | 1 |
| Sasaki, H | 1 |
| Young, GB | 1 |
| Oppenheimer, SR | 1 |
| Gordon, BA | 1 |
| Wells, GA | 1 |
| Assis, LP | 1 |
| Kreeft, JH | 1 |
| Lohuis, NA | 1 |
| Blume, WT | 1 |
| Katz, AA | 1 |
| Hoffman, RS | 1 |
| Silverman, RA | 1 |
| Fleishaker, JC | 1 |
| Pearson, LK | 1 |
| Peters, GR | 1 |
| López-Ariztegui, N | 1 |
| Ochoà, M | 1 |
| Sánchez-Migallón, MJ | 1 |
| Nevado, C | 1 |
| Martín, M | 1 |
| Sharma, S | 1 |
| Dasroy, SK | 1 |
| Mamiya, K | 1 |
| Kojima, K | 1 |
| Yukawa, E | 1 |
| Higuchi, S | 1 |
| Ieiri, I | 1 |
| Ninomiya, H | 1 |
| Tashiro, N | 1 |
| Stark, RJ | 1 |
| Boldyrev, AI | 1 |
| Fleĭs, EP | 1 |
| Vaĭntrub, MIa | 1 |
| Shakir, RA | 1 |
| Nanda, RN | 1 |
| Lambie, DG | 1 |
| Johnson, RH | 1 |
| Troupin, A | 1 |
| Ojemann, LM | 1 |
| Halpern, L | 1 |
| Dodrill, C | 1 |
| Wilkus, R | 1 |
| Friel, P | 1 |
| Feigl, P | 1 |
| Beier, R | 1 |
| Zschiesche, M | 1 |
| Cammann, R | 1 |
| Krüger, H | 1 |
| Glötzner, FL | 1 |
| Samland, O | 1 |
| Dommasch, D | 1 |
| Shapira, Y | 1 |
| Cederbaum, SD | 1 |
| Cancilla, PA | 1 |
| Nielsen, D | 1 |
| Lippe, BM | 1 |
| Livingston, S | 1 |
| Berman, W | 1 |
| Pauli, LL | 1 |
| Onuma, T | 1 |
| Mares, P | 1 |
| Lisková-Bernásková, K | 1 |
| Mudrochová, M | 1 |
| Finestone, AJ | 1 |
| Williams, FF | 1 |
| Glogner, P | 1 |
| Vessell, ES | 1 |
| Passananti, GT | 1 |
| Clow, D | 1 |
| Stephenson, JB | 1 |
| Logan, RW | 1 |
| Jamieson, EC | 1 |
| Gauchel, FD | 1 |
| Lehr, HJ | 1 |
| Gauchel, G | 1 |
| von Harnack, GA | 1 |
| McLellan, DL | 1 |
| Swash, M | 1 |
| Lund, L | 1 |
| Breithardt, G | 1 |
| Loogen, F | 1 |
| Seipel, L | 1 |
| Edwards, VE | 1 |
| Critchley, EM | 1 |
| Clark, DB | 1 |
| Wikler, A | 1 |
| Brittain, RT | 1 |
| Landy, PJ | 1 |
| Igata, A | 1 |
| Murphy, MJ | 1 |
| Goldstein, MN | 1 |
| Shuttleworth, E | 1 |
| Wise, G | 1 |
| Paulson, G | 1 |
| Booker, HE | 1 |
| Darcey, B | 1 |
| Gallagher, BB | 1 |
| Baumel, IP | 1 |
| Mattson, RH | 1 |
| Woodbury, SG | 1 |
| Juul-Jensen, P | 1 |
| Schou, M | 1 |
| Kooiker, JC | 1 |
| Sumi, SM | 1 |
| Hopkins, IJ | 1 |
| Rooney, JC | 1 |
| Ang, MK | 1 |
| Guiang, R | 1 |
| Berger, AR | 1 |
| Melchior, JC | 1 |
| Buchthal, F | 1 |
| Lennox-Buchthal, M | 1 |
| Holcomb, R | 1 |
| Lynn, R | 1 |
| Harvey, B | 1 |
| Sweetman, BJ | 1 |
| Gerber, N | 1 |
| Fischer, KC | 1 |
| Wilson, WP | 1 |
| Behrman, S | 1 |
| Viukari, NM | 2 |
| Aho, K | 1 |
| Brennan, RW | 1 |
| Dehejia, H | 1 |
| Verebely, K | 1 |
| Kalensky, J | 1 |
| Herzka, HS | 1 |
| Allen, CD | 1 |
| Klipstein, FA | 1 |
| Patel, H | 1 |
| Crichton, JU | 1 |
| Pifferi, G | 1 |
| Consonni, P | 1 |
| Banfi, S | 1 |
| Diena, A | 1 |
| Gordon, N | 1 |
| Garrettson, LK | 1 |
| Perel, JM | 1 |
| Dayton, PG | 1 |
| McDowell, FH | 1 |
Reviews
6 reviews available for phenytoin and Ataxia
| Article | Year |
|---|---|
Phenytoin and damage to the cerebellum - a systematic review of published cases.
Topics: Adult; Ataxia; Atrophy; Cerebellar Ataxia; Cerebellar Diseases; Cerebellum; Humans; Phenytoin | 2022 |
[Acute phenytoin poisoning secondary to an interaction with ticlopidine].
Topics: Acute Disease; Aged; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Ataxia; Cerebrovascular Disorde | 1998 |
Biochemical and genetic factors regulating dilantin metabolism in man.
Topics: Aminosalicylic Acids; Animals; Ataxia; Cats; Chlordan; Cycloserine; DDT; Dicumarol; Disulfiram; Enzy | 1971 |
Utility of clinical chemical determinations of drug concentrations in biological fluids.
Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramin | 1971 |
[Long-term treatment of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Ataxia; Electric Countershock; Gastrointestinal Diseases; Humans; Li | 1974 |
[Ataxia associated with infections and toxicosis].
Topics: Abdomen; Adult; Animals; Ataxia; Cerebellar Ataxia; Cerebrovascular Disorders; Demyelinating Disease | 1971 |
Trials
2 trials available for phenytoin and Ataxia
| Article | Year |
|---|---|
Induction of tirilazad clearance by phenytoin.
Topics: Adult; Anticonvulsants; Antioxidants; Ataxia; Cross-Over Studies; Dizziness; Dose-Response Relations | 1998 |
Carbamazepine--a double-blind comparison with phenytoin.
Topics: Adult; Ataxia; Carbamazepine; Clinical Trials as Topic; Drug Evaluation; Epilepsies, Partial; Hemato | 1977 |
Other Studies
81 other studies available for phenytoin and Ataxia
| Article | Year |
|---|---|
N-phenyl-N'-pyridinylureas as anticonvulsant agents.
Topics: Administration, Oral; Animals; Anticonvulsants; Ataxia; Chemical Phenomena; Chemistry; Dose-Response | 1990 |
6-Alkyl-N,N-disubstituted-2-pyridinamines as anticonvulsant agents.
Topics: Aminopyridines; Animals; Ataxia; Blepharoptosis; Chemical Phenomena; Chemistry; Electroshock; Kindli | 1989 |
Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters.
Topics: Amino Alcohols; Animals; Anticonvulsants; Ataxia; Bridged Bicyclo Compounds; Bridged Bicyclo Compoun | 1986 |
6-Alkoxy-N,N-disubstituted-2-pyridinamines as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Ataxia; Male; Mice; Rats; Structure-Activity Relationship | 1987 |
A Phenytoin-Induced Ataxia Mimicking a Stroke.
Topics: Ataxia; Carbamazepine; Female; Humans; Middle Aged; Phenytoin; Stroke; Valproic Acid | 2022 |
Phenytoin-related ataxia in patients with epilepsy: clinical and radiological characteristics.
Topics: Antibodies; Anticonvulsants; Ataxia; Brain; Epilepsy; Female; Folic Acid; Gliadin; GTP-Binding Prote | 2018 |
Phenytoin-induced hypothermia.
Topics: Aftercare; Ataxia; Cytochrome P-450 CYP1A2 Inducers; Diagnosis, Differential; Humans; Hypothermia; L | 2019 |
Status epilepticus in a child secondary to ingestion of skin-lightening cream.
Topics: Anticonvulsants; Ataxia; Eating; Emergencies; Humans; Hydroquinones; Infant; Intubation, Intratrache | 2013 |
Ataxia and dizziness in a patient on hemodialysis.
Topics: Anticonvulsants; Ataxia; Dizziness; Humans; Kidney Failure, Chronic; Male; Middle Aged; Phenytoin; R | 2014 |
Velopharyngeal Incoordination Caused by Phenytoin-Induced Toxicity.
Topics: Adult; Anticonvulsants; Ataxia; Deglutition Disorders; Gastroesophageal Reflux; Humans; Hypertrophy; | 2017 |
Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.
Topics: Alleles; Angiotensin II Type 1 Receptor Blockers; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; At | 2010 |
[Ataxia].
Topics: Anticonvulsants; Antimetabolites, Antineoplastic; Antipsychotic Agents; Ataxia; Fluorouracil; Humans | 2012 |
The ataxic cirrhotic.
Topics: Anticonvulsants; Ataxia; Female; Humans; Liver Cirrhosis, Alcoholic; Middle Aged; Phenytoin; Seizure | 2012 |
ANTICONVULSANTS. I. DIBENZO(A,D)CYCLOHEPTADIENE-5-CARBOXAMIDE AND RELATED COMPOUNDS.
Topics: Amides; Anticonvulsants; Ataxia; Chemistry, Pharmaceutical; Mice; Pentylenetetrazole; Pharmacology; | 1964 |
DIPHENYLHYDANTOIN METABOLISM, BLOOD LEVELS, AND TOXICITY.
Topics: Ataxia; Blood Chemical Analysis; Drug Tolerance; Humans; Mental Disorders; Metabolism; Nystagmus, Pa | 1964 |
DIPHENYLHYDANTOIN AND PHENOBARBITAL TOXICITY. THE ROLE OF LIVER DISEASE.
Topics: Ataxia; Barbiturates; Blood Chemical Analysis; Chromatography; Drug Tolerance; Hepatitis; Hepatitis | 1964 |
[TREATMENT OF EPILEPSY WITH 3-ETHOXYCARBO-5,5-DIPHENYLHYDANTOIN (P-6127), A NEW ANTICONVULSANT].
Topics: Anticonvulsants; Ataxia; Blood Chemical Analysis; Drug Therapy; Electroencephalography; Epilepsy; Ep | 1964 |
NEUROLOGICAL SEQUELAE FOLLOWING DILANTIN OVERDOSE IN A PATIENT AND IN EXPERIMENTAL ANIMALS.
Topics: Adolescent; Ataxia; Biomedical Research; Cats; Chlordiazepoxide; Drug Therapy; Epilepsy; Humans; Neu | 1965 |
SYNDROME OF GINGIVAL HYPERPLASIA, HIRSUTISM, AND CONVULSIONS; DILANTIN INTOXICATION WITHOUT DILANTIN.
Topics: Ataxia; Brain Diseases; Child; Chlorpheniramine; Diagnosis, Differential; Diencephalon; Drug Therapy | 1965 |
Acute colchicine intoxication in a child: a case report.
Topics: Acute Disease; Alopecia; Ataxia; Blood Transfusion; Case Management; Child, Preschool; Colchicine; C | 2007 |
[Acute cerebellar ataxia associated with infectious mononucleosis].
Topics: Adolescent; Adult; Ataxia; Blood Cell Count; Cerebellar Diseases; Child, Preschool; Encephalitis; Hu | 1967 |
Studies on Dilantin intoxication. I. Ultrastructural analogies with the lipoidoses.
Topics: Animals; Ataxia; Cerebellar Cortex; Coma; Cytoplasmic Granules; Lipidoses; Male; Microscopy, Electro | 1967 |
Phenytoin (Dilantin) intoxication.
Topics: Adolescent; Adult; Aged; Anorexia Nervosa; Ataxia; Child; Epilepsy; Female; Humans; Male; Mental Dis | 1967 |
Downbeat nystagmus with phenytoin.
Topics: Adult; Ataxia; Central Nervous System Diseases; Female; Humans; Male; Middle Aged; Nystagmus, Pathol | 1982 |
Interaction of amiodarone and diphenylhydantoin.
Topics: Aged; Amiodarone; Ataxia; Benzofurans; Drug Interactions; Humans; Male; Myocardial Infarction; Pheny | 1984 |
Paroxysmal limb hemiataxia with crossed facial paresthesias in multiple sclerosis.
Topics: Adult; Ataxia; Carbamazepine; Face; Humans; Male; Multiple Sclerosis; Paresthesia; Phenytoin; Thromb | 1983 |
Drug interactions on an alcohol unit.
Topics: Adult; Alcoholism; Ataxia; Diagnosis, Differential; Drug Interactions; Epilepsy; Humans; Male; Oxaze | 1982 |
[Pharmacological studies on the functional development of the central nervous system in first generation rats born to phenytoin-treated mothers (author's transl)].
Topics: Animals; Animals, Newborn; Ataxia; Birth Rate; Brain; Catalepsy; Diazepam; Eye; Feeding Behavior; Fe | 1982 |
Phenothiazine-induced phenytoin intoxication.
Topics: Adult; Aged; Ataxia; Drug Interactions; Dysarthria; Female; Humans; Male; Nystagmus, Pathologic; Phe | 1980 |
Control of late postoperative ventricular arrhythmias with phenytoin in young patients.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Ataxia; Child; Dose-Response Relationship, Drug; Electrocar | 1980 |
Phenytoin elimination kinetics in two children with drug intoxication.
Topics: Ataxia; Child; Female; Humans; Kinetics; Nystagmus, Pathologic; Phenytoin | 1980 |
Ataxia in institutionalized patients with epilepsy.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Anticonvulsants; Ataxia; Cerebellar Ataxia; Epilepsy; | 1994 |
Phenytoin toxicity from smoking crack cocaine adulterated with phenytoin.
Topics: Adult; Ataxia; Charcoal; Crack Cocaine; Drug Contamination; Gastric Lavage; Humans; Male; Middle Age | 1993 |
Images in clinical medicine. Gingival hyperplasia induced by phenytoin.
Topics: Adolescent; Anticonvulsants; Ataxia; Epilepsy, Tonic-Clonic; Gingiva; Gingival Hyperplasia; Humans; | 2000 |
Phenytoin intoxication induced by fluvoxamine.
Topics: Alleles; Anticonvulsants; Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydroxylases; A | 2001 |
Index of suspicion.
Topics: Adolescent; Anticonvulsants; Ataxia; Cellulitis; Child; Child, Preschool; Creatinine; Diagnosis, Dif | 2002 |
Spasticity due to phenytoin toxicity.
Topics: Adult; Ataxia; Epilepsy, Tonic-Clonic; Humans; Male; Muscle Spasticity; Phenytoin; Reflex, Abnormal | 1979 |
[Neurologic complications following medical treatment of epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Ataxia; Benzodiazepines; Consciousness Disorders; Dysarthria; Ey | 1979 |
Comparative trial of valproate sodium and clonazepam in chronic epilepsy.
Topics: Adult; Ataxia; Benzodiazepinones; Chronic Disease; Clonazepam; Drug Therapy, Combination; Epilepsy; | 1979 |
[Phenytoin intoxication and serum level].
Topics: Adolescent; Adult; Aged; Ataxia; Athetosis; Attention; Child; Child, Preschool; Chorea; Dose-Respons | 1978 |
[Severe cerebellar lesions caused by diphenylhydantoin--a contribution to the problem of hydantoin poisoning].
Topics: Adolescent; Ataxia; Dietary Proteins; Dysarthria; Encephalitis; Epilepsy; Female; Humans; Nystagmus, | 1978 |
[Brain stem seizures with circumscrbed elementary symptoms].
Topics: Adult; Amitriptyline; Ataxia; Brain Neoplasms; Brain Stem; Carbamazepine; Epilepsy; Female; Humans; | 1976 |
Familial poliodystrophy, mitochondrial myopathy, and lactate acidemia.
Topics: Adolescent; Ataxia; Cerebral Cortex; Child; Child, Preschool; Diazepam; Diffuse Cerebral Sclerosis o | 1975 |
Anticonvulsant drug blood levels.
Topics: Anticonvulsants; Ataxia; Diplopia; Drug Therapy, Combination; Epilepsy; Humans; Nystagmus, Pathologi | 1975 |
Deteriorating epilepsies: severely deteriorated cases.
Topics: Adult; Anticonvulsants; Ataxia; Brain Damage, Chronic; Diagnosis, Differential; Drug Therapy, Combin | 1990 |
Convulsant action of diphenylhydantoin overdose in young rats.
Topics: Animals; Animals, Newborn; Ataxia; Disease Susceptibility; Dose-Response Relationship, Drug; Male; P | 1987 |
Generic substitution resulting in toxicity.
Topics: Aged; Ataxia; Biological Availability; Female; Humans; Phenytoin; Therapeutic Equivalency | 1985 |
[Unfavorable and problematic drug combinations. IV].
Topics: Amphetamine; Ataxia; Bone Marrow; Cerebral Hemorrhage; Depression, Chemical; Dicumarol; Dihydroxyphe | 1970 |
Errors in phenytoin dosage.
Topics: Ataxia; Child; Child, Preschool; Epilepsy; Female; Headache; Humans; Male; Medication Errors; Phenyt | 1973 |
[Diphenylhydantoin in children. Clinico-pharmacological studies].
Topics: Adolescent; Alkaline Phosphatase; Ataxia; Body Weight; Calcium; Child; Child, Preschool; Diplopia; D | 1973 |
Choreo-athetosis and encephalopathy induced by phenytoin.
Topics: Adolescent; Adult; Ataxia; Athetosis; Carbamazepine; Chorea; Diplopia; Electroencephalography; Epile | 1974 |
Anticonvulsant effect of diphenylhydantoin relative to plasma levels. A prospective three-year study in ambulant patients with generalized epileptic seizures.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Ataxia; Chromatography, Gas; Epilepsy; Epilepsy, Tonic-Clo | 1974 |
Side effects of clonazepam therapy.
Topics: Adolescent; Adult; Aggression; Ataxia; Benzodiazepinones; Clonazepam; Drug Interactions; Epilepsy; E | 1974 |
An adult form of acanthocytosis.
Topics: Abetalipoproteinemia; Adult; Ataxia; Diazepam; Female; Haloperidol; Humans; Huntington Disease; Hydr | 1967 |
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Ne | 1966 |
"Dilatin" overdosage.
Topics: Anticonvulsants; Ataxia; Brain Neoplasms; Carbamazepine; Diagnosis, Differential; Dibenzazepines; Ep | 1968 |
Diphenylhydantoin.
Topics: Affective Symptoms; Arrhythmias, Cardiac; Ataxia; Carbamazepine; Central Nervous System Diseases; Ch | 1971 |
Diphenylhydantoin-induced asterixis. A clinical study.
Topics: Ataxia; Electroencephalography; Electromyography; Epilepsy; Female; Humans; Male; Middle Aged; Nysta | 1974 |
Choreoathetosis and diphenylhydantoin intoxication.
Topics: Adolescent; Adult; Ataxia; Athetosis; Chorea; Diplopia; Female; Humans; Male; Nystagmus, Pathologic; | 1974 |
Serum concentrations of free diphenylhydantoin and their relationship to clinical intoxication.
Topics: Ataxia; Blood Proteins; Chromatography, Gas; Humans; Methods; Nystagmus, Pathologic; Phenytoin; Prot | 1973 |
Primidone, diphenylhydantoin and phenobarbital. Aspects of acute and chronic toxicity.
Topics: Ataxia; Chromatography, Gas; Drug Tolerance; Epilepsy; Humans; Nystagmus, Pathologic; Phenobarbital; | 1973 |
Letter: Permanent brain damage after lithium intoxication.
Topics: Adult; Ataxia; Brain Damage, Chronic; Diuresis; Female; Humans; Lithium; Middle Aged; Nystagmus, Pat | 1973 |
Movement disorder as a manifestation of diphenylhydantoin intoxication.
Topics: Adult; Ataxia; Athetosis; Chorea; Epilepsy; Female; Humans; Middle Aged; Nystagmus, Pathologic; Phen | 1974 |
Phenytoin intoxication in childhood due to incorrect prescribing, dispensing and administration of suspensions.
Topics: Age Factors; Ataxia; Child; Child, Preschool; Drug Prescriptions; Epilepsy, Tonic-Clonic; Female; Hu | 1969 |
Diphenylhydantoin (Dilantin) neurotoxicity--a deceptive syndrome.
Topics: Aged; Ataxia; Capsules; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Humans; Male; Medication Er | 1969 |
The ineffectiveness of diphenylhydantoin in preventing febrile convulsions in the age of greatest risk, under three years.
Topics: Age Factors; Ataxia; Attention; Child, Preschool; Epilepsy, Absence; Fever; Humans; Infant; Phenytoi | 1971 |
Intoxication with 5,5-diphenylhydantoin (Dilantin): clinical features, blood levels, urinary metabolites, and metabolic changes in a child.
Topics: Ataxia; Child, Preschool; Glucuronates; Half-Life; Humans; Hyperglycemia; Insulin; Male; Movement Di | 1972 |
Adverse effects of hydantoins.
Topics: Ataxia; Drug Hypersensitivity; Folic Acid; Humans; Neurologic Manifestations; Phenytoin; Skin Manife | 1971 |
Methylphenidate and the hyperkinetic state.
Topics: Ataxia; Child; Drug Synergism; Feeding and Eating Disorders; Humans; Hyperkinesis; Hypertension; Met | 1971 |
Delayed phenytoin idiosyncrasy.
Topics: Ataxia; Epilepsy; Humans; Nystagmus, Pathologic; Phenytoin | 1969 |
Intolerance to diphenylhydantoin in five cases of Vogt-Spielmeyer disease.
Topics: Ataxia; Brain; Humans; L-Lactate Dehydrogenase; Lipidoses; Phenobarbital; Phenytoin; Primidone; Seiz | 1969 |
Digoxin-phenytoin interaction.
Topics: Ataxia; Cerebellar Diseases; Coma; Digoxin; Humans; Male; Middle Aged; Phenytoin | 1970 |
Diphenylhydantoin intoxication attendant to slow inactivation of isoniazid.
Topics: Animals; Ataxia; Cats; Drug Tolerance; Epilepsy; Genetics, Medical; Humans; Isoniazid; Nystagmus, Pa | 1970 |
[Therapy of epilepsy in mentally retarded children. Neuropsychiatric disorders caused by diphenylhydantoin].
Topics: Adolescent; Affective Symptoms; Ataxia; Child; Epilepsy; Humans; Intellectual Disability; Male; Musc | 1970 |
Brain folate and diphenylhydantoin (DPH) concentrations in ataxic cats receiving DPH.
Topics: Animals; Ataxia; Brain; Cats; Folic Acid; Liver; Phenytoin | 1970 |
The neurologic hazards of diphenylhydantoin in childhood.
Topics: Adolescent; Ataxia; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Neurologic Mani | 1968 |
Management of epilepsy with diphenylhydantoin sodium. Dosage regulation for problem patients.
Topics: Adult; Antitubercular Agents; Ataxia; Drug Tolerance; Epilepsy; Hospitalization; Humans; Nystagmus, | 1968 |
2,3-benzoxazines. IX. Synthesis and central nervous system depressant activity of some 3,6- and 3,7-disubstituted 1H-3,4-dihydro-2,3-benzoxazines.
Topics: Analgesia; Animals; Aspirin; Ataxia; Barbiturates; Central Nervous System; Chlordiazepoxide; Chlorpr | 1969 |
Use of diphenylhydantoin in epilepsy treatment.
Topics: Ataxia; Chemical and Drug Induced Liver Injury; Epilepsy; Humans; Necrosis; Nervous System Diseases; | 1969 |
Methylphenidate interaction with both anticonvulsants and ethyl biscoumacetate.
Topics: Adult; Anticonvulsants; Ataxia; Brain Diseases; Child, Preschool; Depression, Chemical; Ethyl Biscou | 1969 |
Depression of prahydroxylation of diphenylhydantoin by antituberculosis chemotherapy.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Anticonvulsants; Ataxia; Cycloserine; Drug Incompatib | 1966 |