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phenytoin and Asystole

phenytoin has been researched along with Asystole in 41 studies

Research Excerpts

ExcerptRelevanceReference
"A case of complete atrioventricular block with ventricular asystole in a patient receiving intravenous phenytoin is presented."7.69Complete atrioventricular block with ventricular asystole following infusion of intravenous phenytoin. ( Ciccone, A; Randazzo, DN; Schweitzer, P; Winters, SL, 1995)
"Nine of 10 adults, previously healthy patients who suffered cardiac arrest during or after anesthesia, recovered nearly complete neurological function when given iv phenytoin, 7 mg/kg."5.05Phenytoin for brain resuscitation after cardiac arrest: an uncontrolled clinical trial. ( Aldrete, JA; Mazzia, VD; Romo-Salas, F; Tan, SL, 1981)
"A case of complete atrioventricular block with ventricular asystole in a patient receiving intravenous phenytoin is presented."3.69Complete atrioventricular block with ventricular asystole following infusion of intravenous phenytoin. ( Ciccone, A; Randazzo, DN; Schweitzer, P; Winters, SL, 1995)
" Two families had members who had been treated with phenytoin sodium for seizures and had died suddenly when the medication was discontinued."3.67A family history of seizures associated with sudden cardiac deaths. ( Bricker, JT; Garson, A; Gillette, PC, 1984)
"Evidence suggests that untreated obstructive sleep apnea (OSA) can lead to hypertension, cardiovascular disease, and stroke."1.32Transient obstructive sleep apnea and asystole in association with presumed viral encephalopathy. ( Berger, HA; Dyken, ME; Yamada, T, 2003)
"We conclude that after prolonged cardiac arrest, the already established brain damage mitigating effect of mild immediate postarrest hypothermia might be enhanced by thiopental, and perhaps then further enhanced by adding phenytoin and methylprednisolone."1.31Thiopental combination treatments for cerebral resuscitation after prolonged cardiac arrest in dogs. Exploratory outcome study. ( Capone, A; Ebmeyer, U; Radovsky, A; Safar, P; Stezoski, SW; Tanigawa, K; Xiao, F, 2000)
"A 75-year-old man suffered a cardiac arrest and severe anoxic encephalopathy."1.30Periodic complexes, absence-like status and suppression-burst pattern in coma following cardiorespiratory arrest. ( Chemmale, J; Devrajan, VN; Ganji, SS; McDonald, L; Palliyath, S, 1997)
"In complete global ischemia (cardiac arrest) reperfusion is characterized by an immediate reactive hyperemia followed within 20-30 min by a delayed hypoperfusion state."1.29[Cerebral protection]. ( Cattaneo, AD, 1993)
"We report an additional patient with cardiac arrest during a mesiobasal left temporal lobe seizure discharge."1.28Cardiac arrest due to partial epileptic seizures. ( Gudjonsson, O; Liedholm, LJ, 1992)
"Documentation of the mechanism of sudden death is described in a patient with a prolonged QT interval."1.27Documented sudden cardiac death in prolonged QT syndrome. ( Brown, EJ; Cohn, PF; Mallis, GI; Vlay, SC, 1984)
"should be implemented for each seizure case that requires a decision on the urgent need for therapeutic anticonvulsant levels, whether by mechanical infusion, manual intravenous push, or oral loading."1.27Cardiopulmonary arrest following intravenous phenytoin loading. ( Coleridge, ST; York, RC, 1988)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199027 (65.85)18.7374
1990's7 (17.07)18.2507
2000's4 (9.76)29.6817
2010's3 (7.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shihabuddin, BS1
Herlopian, AS1
Greenfield, LJ1
Siebert, WJ1
McGavigan, AD1
Dyken, ME1
Yamada, T1
Berger, HA1
Keeran, M1
Goldschlager, AW1
Karliner, JS1
Unger, AH1
Sklaroff, HJ1
Stannard, M1
MacKinnon, M1
Vlay, SC1
Mallis, GI1
Brown, EJ1
Cohn, PF1
Bricker, JT1
Garson, A1
Gillette, PC1
Aldrete, JA2
Romo-Salas, F1
Mazzia, VD1
Tan, SL1
Hendricks, HH1
Artru, AA1
Michenfelder, JD1
Randazzo, DN1
Ciccone, A1
Schweitzer, P1
Winters, SL1
Cattaneo, AD1
Ganji, SS1
Palliyath, S1
Chemmale, J1
Devrajan, VN1
McDonald, L1
Berry, JM1
Kowalski, A1
Fletcher, SA1
Lin, SY1
Wu, CT1
Yeh, CC1
Liu, ST1
Ho, ST1
Wong, CS1
Ebmeyer, U1
Safar, P2
Radovsky, A2
Xiao, F1
Capone, A1
Tanigawa, K1
Stezoski, SW1
DeToledo, JC1
Lowe, MR1
Rabinstein, A1
Villaviza, N1
Behringer, W1
Kentner, R1
Wu, X1
Tisherman, SA1
Stezoski, WS1
Henchir, J1
Prueckner, S1
Zoneraich, S1
Zoneraich, O1
Siegel, J1
Culpin, PA1
Liedholm, LJ1
Gudjonsson, O1
Panegyres, PK1
Rischbieth, RH1
Fahn, S1
York, RC1
Coleridge, ST1
Lawrie, DM1
Higgins, MR1
Godman, MJ1
Oliver, MF1
Julian, DG1
Donald, KW1
Wit, AL1
Rosen, MR1
Hoffman, BF1
Raynaud, R1
Brochier, M1
Fauchier, JP1
Raynaud, P1
Gsell, S1
Ossenkopp, G1
Weigeldt, HD1
Kanarek, KS1
Thomson, PD1
Levin, SE1
Sloman, G1
Khero, BA1
Mullins, CB1
Herbinger, W1
Birch, AA1
Mitchell, GD1
Playford, GA1
Lang, CA1
Scriabine, A1
Kostis, J1
Nigri, A1
Bellet, S1
Morgan, G1
Rival, J1
Wood, RA1
Frisius, H1
Beyer, KH1

Reviews

4 reviews available for phenytoin and Asystole

ArticleYear
Requirement for cardiac telemetry during intravenous phenytoin infusion: guideline fact or guideline fiction?
    Internal medicine journal, 2013, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Ca

2013
Posthypoxic action myoclonus: literature review update.
    Advances in neurology, 1986, Volume: 43

    Topics: Adult; Clonazepam; Coma; Electroencephalography; Female; Functional Laterality; Heart Arrest; Humans

1986
Electrophysiology and pharmacology of cardiac arrhythmias. II. Relationship of normal and abnormal electrical activity of cardiac fibers to the genesis of arrhythmias. A Automaticity.
    American heart journal, 1974, Volume: 88, Issue:4

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atrial Function; Atrioventricular Node; Dogs; Elec

1974
Changing concepts in the care of patients with acute myocardial infarction.
    The Medical journal of Australia, 1969, Jun-07, Volume: 1, Issue:23

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Blood Gas Analysis; Bundle-Branch Block; Cardiac Output;

1969

Trials

2 trials available for phenytoin and Asystole

ArticleYear
Phenytoin for brain resuscitation after cardiac arrest: an uncontrolled clinical trial.
    Critical care medicine, 1981, Volume: 9, Issue:6

    Topics: Adult; Anesthesia; Brain Damage, Chronic; Clinical Trials as Topic; Female; Heart Arrest; Humans; Ma

1981
Changes in serum potassium response to succinylcholine following trauma.
    JAMA, 1969, Oct-20, Volume: 210, Issue:3

    Topics: Burns; Carbon Dioxide; Fractures, Bone; Heart Arrest; Humans; Hyperkalemia; Injections, Intravenous;

1969

Other Studies

35 other studies available for phenytoin and Asystole

ArticleYear
Intravenous phenytoin: rate of administration is critical.
    Alberta RN, 2013,Spring, Volume: 69, Issue:1

    Topics: Aged; Anticonvulsants; Canada; Heart Arrest; Humans; Infusions, Intravenous; Medication Errors; Phen

2013
Ictal asystole in epilepsy patients undergoing inpatient video-EEG monitoring.
    Neurosciences (Riyadh, Saudi Arabia), 2014, Volume: 19, Issue:4

    Topics: Aged; Anticonvulsants; Bradycardia; Electroencephalography; Epilepsy, Temporal Lobe; Female; Heart A

2014
Transient obstructive sleep apnea and asystole in association with presumed viral encephalopathy.
    Neurology, 2003, May-27, Volume: 60, Issue:10

    Topics: Adult; Bradycardia; Continuous Positive Airway Pressure; Encephalitis, Viral; Heart Arrest; Humans;

2003
Cardiac arrest following intravenous administration of diphenylhydantoin.
    The Journal of the Oklahoma State Medical Association, 1967, Volume: 60, Issue:6

    Topics: Aged; Female; Heart Arrest; Humans; Injections, Intravenous; Phenytoin

1967
Ventricular standstill after intravenous diphenylhydantoin.
    American heart journal, 1967, Volume: 74, Issue:3

    Topics: Aged; Electrocardiography; Heart Arrest; Humans; Injections, Intravenous; Male; Phenytoin; Tachycard

1967
Fatalities following intravenous use of sodium diphenylhydantoin for cardiac arrhythmias. Report of two cases.
    JAMA, 1967, Apr-24, Volume: 200, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Heart Arrest; Humans; Injections, Intraveno

1967
Resuscitation from cardiac arrest in the presence of acute pulmonary oedema.
    The Medical journal of Australia, 1967, Nov-25, Volume: 2, Issue:22

    Topics: Aged; Cardiac Output; Electrocardiography; Heart Arrest; Heart Massage; Heart Rate; Humans; Male; Ph

1967
Documented sudden cardiac death in prolonged QT syndrome.
    Archives of internal medicine, 1984, Volume: 144, Issue:4

    Topics: Aged; Death, Sudden; Diabetes Complications; Digoxin; Electrocardiography; Epilepsy, Tonic-Clonic; F

1984
A family history of seizures associated with sudden cardiac deaths.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:9

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Child; Death, Sudden; Electrocardiography; Female; Heart Ar

1984
Bias in the treatment of patients after cardiac arrest.
    Critical care medicine, 1982, Volume: 10, Issue:2

    Topics: Heart Arrest; Humans; Phenytoin; Resuscitation

1982
Anoxic cerebral potassium accumulation reduced by phenytoin: mechanism of cerebral protection?
    Anesthesia and analgesia, 1981, Volume: 60, Issue:1

    Topics: Animals; Cisterna Magna; Dose-Response Relationship, Drug; Heart Arrest; Hypothermia, Induced; Hypox

1981
Complete atrioventricular block with ventricular asystole following infusion of intravenous phenytoin.
    Journal of electrocardiology, 1995, Volume: 28, Issue:2

    Topics: Aged; Electrocardiography; Female; Heart Arrest; Heart Block; Humans; Infusions, Intravenous; Phenyt

1995
[Cerebral protection].
    Minerva anestesiologica, 1993, Volume: 59, Issue:9

    Topics: Adrenal Cortex Hormones; Anesthetics; Barbiturates; Benzodiazepines; Brain Ischemia; Calcium Channel

1993
Periodic complexes, absence-like status and suppression-burst pattern in coma following cardiorespiratory arrest.
    Clinical EEG (electroencephalography), 1997, Volume: 28, Issue:2

    Topics: Aged; Anticonvulsants; Brain; Coma; Diazepam; Electroencephalography; Epilepsy, Absence; Heart Arres

1997
Sudden asystole during craniotomy: unrecognized phenytoin toxicity.
    Journal of neurosurgical anesthesiology, 1999, Volume: 11, Issue:1

    Topics: Anticonvulsants; Craniotomy; Diagnosis, Differential; Female; Heart Arrest; Humans; Infusions, Intra

1999
Ephedrine-induced complete atrioventricular block with ventricular asystole during rapid concomitant phenytoin infusion: a case report.
    Acta anaesthesiologica Sinica, 1999, Volume: 37, Issue:1

    Topics: Anticonvulsants; Ephedrine; Female; Heart Arrest; Heart Block; Humans; Middle Aged; Phenytoin

1999
Thiopental combination treatments for cerebral resuscitation after prolonged cardiac arrest in dogs. Exploratory outcome study.
    Resuscitation, 2000, Volume: 45, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Brain Damage, Chronic; Dogs; Drug Therapy, Combination; Heart Arres

2000
Cardiac arrest after fast intravenous infusion of phenytoin mistaken for fosphenytoin.
    Epilepsia, 2001, Volume: 42, Issue:2

    Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Costs;

2001
Thiopental and phenytoin by aortic arch flush for cerebral preservation during exsanguination cardiac arrest of 20 minutes in dogs. An exploratory study.
    Resuscitation, 2001, Volume: 49, Issue:1

    Topics: Animals; Anticonvulsants; Aorta, Thoracic; Brain Ischemia; Cardiopulmonary Resuscitation; Cerebrovas

2001
Sudden death following intravenous sodium diphenylhydantoin.
    American heart journal, 1976, Volume: 91, Issue:3

    Topics: Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Death, Sudden; Female; Heart Arrest; Human

1976
Anaesthetic death in a four-and-a-half-year-old Alsation.
    The Veterinary record, 1978, Sep-16, Volume: 103, Issue:12

    Topics: Anesthesia, Intravenous; Animals; Dog Diseases; Dogs; Female; Heart Arrest; Phenobarbital; Phenytoin

1978
Cardiac arrest due to partial epileptic seizures.
    Neurology, 1992, Volume: 42, Issue:4

    Topics: Adult; Electrocardiography; Electroencephalography; Epilepsies, Partial; Female; Heart Arrest; Human

1992
Fatal phenytoin warfarin interaction.
    Postgraduate medical journal, 1991, Volume: 67, Issue:783

    Topics: Aged; Drug Synergism; Drug Therapy, Combination; Heart Arrest; Humans; Male; Myocardial Infarction;

1991
Phenytoin's value as a neuroplegic drug in brain preservation.
    Resuscitation, 1986, Volume: 13, Issue:2

    Topics: Adult; Aged; Female; Heart Arrest; Humans; Male; Middle Aged; Phenytoin; Pupil; Unconsciousness

1986
Cardiopulmonary arrest following intravenous phenytoin loading.
    The American journal of emergency medicine, 1988, Volume: 6, Issue:3

    Topics: Aged; Female; Heart Arrest; Humans; Infusions, Intravenous; Male; Middle Aged; Phenytoin; Seizures

1988
Ventricular fibrillation complicating acute myocardial infarction.
    Lancet (London, England), 1968, Sep-07, Volume: 2, Issue:7567

    Topics: Age Factors; Arrhythmias, Cardiac; Female; Follow-Up Studies; Heart Arrest; Humans; Lidocaine; Male;

1968
Diphenylhydantoin.
    The Medical letter on drugs and therapeutics, 1971, Jun-11, Volume: 13, Issue:12

    Topics: Affective Symptoms; Arrhythmias, Cardiac; Ataxia; Carbamazepine; Central Nervous System Diseases; Ch

1971
[Adverse effects of recent ventricular anti-arrhythmia drug].
    La Vie medicale au Canada francais, 1972, Volume: 1, Issue:2

    Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Drug Synergism; Electro

1972
[Apnea and heart arrest following distraneurin therapy. Clinical, neurophysiological and neuropathological aspects].
    Der Nervenarzt, 1972, Volume: 43, Issue:12

    Topics: Adult; Apnea; Basal Ganglia; Cerebral Cortex; Chlormethiazole; Drug Synergism; Electroencephalograph

1972
The management of imipramine (Tofranil) intoxication in children.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, May-19, Volume: 47, Issue:19

    Topics: Adult; Anticonvulsants; Arrhythmias, Cardiac; Electrocardiography; Emergencies; Female; Gastric Lava

1973
Cardiac syncope due to glossopharyngeal neuralgia. Treatment with a transvenous pacemaker.
    Archives of internal medicine, 1971, Volume: 128, Issue:5

    Topics: Adult; Bradycardia; Denervation; Female; Glossopharyngeal Nerve; Heart Arrest; Humans; Neuralgia; Pa

1971
[Result report of a control by an apparatus of 208 myocardial infarct patients in an intensive care station. Preliminary report].
    Wiener medizinische Wochenschrift (1946), 1971, Jun-19, Volume: 121, Issue:25

    Topics: Adult; Aged; Arrhythmias, Cardiac; Atropine; Austria; Digitalis Glycosides; Electric Countershock; E

1971
Some aspects of interaction between diphenylhydantoin and digoxin by simultaneous administration to dogs.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3

    Topics: Animals; Aorta; Blood Pressure; Blood Volume; Cardiac Output; Digoxin; Dogs; Electrocardiography; Fe

1970
Sinoatrial arrest: an interaction between phenytoin and lignocaine.
    British medical journal, 1971, Mar-20, Volume: 1, Issue:5750

    Topics: Drug Synergism; Electrocardiography; Heart Arrest; Humans; Lidocaine; Male; Middle Aged; Myocardial

1971
[A severe quinine poisoning: clinic, toxicology and therapy].
    Archiv fur Toxikologie, 1969, Volume: 24, Issue:2

    Topics: Adult; Diuresis; Electrocardiography; Eye Manifestations; Female; Forensic Medicine; Gastric Juice;

1969