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phenytoin and Arthritis, Rheumatoid

phenytoin has been researched along with Arthritis, Rheumatoid in 16 studies

Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

Research Excerpts

ExcerptRelevanceReference
"To evaluate efficacy of phenytoin in modifying the course of rheumatoid arthritis (RA) by comparing it to gold (auranofin) and chloroquine."9.08Comparison of phenytoin with auranofin and chloroquine in rheumatoid arthritis--a double blind study. ( Ahmed, N; Askar, MA; Kumar, TR; Menon, GN; Naidu, MU; Rao, UR; Sarada, P; Shantaram, V; Shobha, U; Venubabu, K, 1995)
"In an open study, thirty-five patients with active rheumatoid arthritis were treated with phenytoin."9.07Evaluation of phenytoin in rheumatoid arthritis--an open study. ( Anuradha, RT; Naidu, MU; Ramesh Kumar, T; Rao, UR, 1991)
"The anticonvulsant drug phenytoin has several interesting immunological properties which could theoretically be of benefit in the treatment of rheumatoid arthritis."9.06Pilot study of phenytoin in rheumatoid arthritis. ( Clark, B; Macfarlane, DG; Panayi, GS, 1986)
"Phenytoin has known immunosuppressive properties, and a recent pilot study has indicated that it may have a second line effect in rheumatoid arthritis (RA)."9.06Comparison of phenytoin and gold as second line drugs in rheumatoid arthritis. ( Capell, HA; Fraser, SM; Hunter, JA; Richards, IM, 1987)
"In a prospective open study, 18 patients with active rheumatoid arthritis were treated with phenytoin (300 mg/day) for 32 weeks."7.67Phenytoin in rheumatoid arthritis. ( Grindulis, KA; Nichol, FE; Oldham, R, 1986)
"To evaluate efficacy of phenytoin in modifying the course of rheumatoid arthritis (RA) by comparing it to gold (auranofin) and chloroquine."5.08Comparison of phenytoin with auranofin and chloroquine in rheumatoid arthritis--a double blind study. ( Ahmed, N; Askar, MA; Kumar, TR; Menon, GN; Naidu, MU; Rao, UR; Sarada, P; Shantaram, V; Shobha, U; Venubabu, K, 1995)
"In an open study, thirty-five patients with active rheumatoid arthritis were treated with phenytoin."5.07Evaluation of phenytoin in rheumatoid arthritis--an open study. ( Anuradha, RT; Naidu, MU; Ramesh Kumar, T; Rao, UR, 1991)
"The anticonvulsant drug phenytoin has several interesting immunological properties which could theoretically be of benefit in the treatment of rheumatoid arthritis."5.06Pilot study of phenytoin in rheumatoid arthritis. ( Clark, B; Macfarlane, DG; Panayi, GS, 1986)
"Phenytoin has known immunosuppressive properties, and a recent pilot study has indicated that it may have a second line effect in rheumatoid arthritis (RA)."5.06Comparison of phenytoin and gold as second line drugs in rheumatoid arthritis. ( Capell, HA; Fraser, SM; Hunter, JA; Richards, IM, 1987)
"In a prospective open study, 18 patients with active rheumatoid arthritis were treated with phenytoin (300 mg/day) for 32 weeks."3.67Phenytoin in rheumatoid arthritis. ( Grindulis, KA; Nichol, FE; Oldham, R, 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's2 (12.50)18.2507
2000's0 (0.00)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Parada-Turska, J1
Nowicka-Stążka, P1
Majdan, M1
Jabłoński, M1
Turski, WA1
Rzeski, W1
Hart, C1
Kinney, MO1
McCarron, MO1
Furst, DE1
Bobrove, AM1
Isobe, T1
Tomita, M1
Matsumoto, J1
Itoh, T1
Fujita, T1
Rao, UR2
Naidu, MU2
Kumar, TR1
Shobha, U1
Askar, MA1
Ahmed, N1
Sarada, P1
Venubabu, K1
Shantaram, V1
Menon, GN1
Ramesh Kumar, T1
Anuradha, RT1
Grindulis, KA2
Nichol, FE2
Oldham, R2
Macfarlane, DG1
Clark, B1
Panayi, GS1
Richards, IM1
Fraser, SM1
Hunter, JA1
Capell, HA1
Harpey, JP1
Moore, DS1
Nally, FF1
Stern, LZ1
Gruener, R1
Amundsen, P1
Markkanen, T1
Peltola, O1
Naess, K1

Reviews

1 review available for phenytoin and Arthritis, Rheumatoid

ArticleYear
Lupus-like syndromes induced by drugs.
    Annals of allergy, 1974, Volume: 33, Issue:5

    Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stra

1974

Trials

4 trials available for phenytoin and Arthritis, Rheumatoid

ArticleYear
Comparison of phenytoin with auranofin and chloroquine in rheumatoid arthritis--a double blind study.
    The Journal of rheumatology, 1995, Volume: 22, Issue:7

    Topics: Adult; Analysis of Variance; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Chloroquine; Do

1995
Evaluation of phenytoin in rheumatoid arthritis--an open study.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:5

    Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Phenytoin

1991
Pilot study of phenytoin in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1986, Volume: 45, Issue:11

    Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Phe

1986
Comparison of phenytoin and gold as second line drugs in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1987, Volume: 46, Issue:9

    Topics: Arthritis, Rheumatoid; Gold; Humans; Phenytoin; Random Allocation; Rheumatoid Factor

1987

Other Studies

11 other studies available for phenytoin and Arthritis, Rheumatoid

ArticleYear
Anti-epileptic drugs inhibit viability of synoviocytes in vitro.
    Annals of agricultural and environmental medicine : AAEM, 2013, Volume: 20, Issue:3

    Topics: Animals; Anticonvulsants; Arthritis, Rheumatoid; Carbamazepine; Cell Proliferation; Cell Survival; C

2013
Posterior reversible encephalopathy syndrome and oral methotrexate.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:6

    Topics: Aged; Anticonvulsants; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Brain; Female;

2012
Use of ibuprofen in unusual circumstances.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersens

1984
Possible beneficial effects of phenytoin for rheumatoid arthritis.
    Arthritis and rheumatism, 1983, Volume: 26, Issue:1

    Topics: Arthritis, Rheumatoid; Humans; Phenytoin

1983
Hematologic and immunologic aberrations in patients under diphenylhydantoin administration.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1983, Volume: 46, Issue:1

    Topics: Adolescent; Aged; Anticonvulsants; Arthritis, Rheumatoid; Female; Humans; Infectious Mononucleosis;

1983
Phenytoin in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1988, Volume: 47, Issue:3

    Topics: Arthritis, Rheumatoid; Humans; Phenytoin

1988
Phenytoin in rheumatoid arthritis.
    The Journal of rheumatology, 1986, Volume: 13, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Viscosity; C-Reactive Protein; F

1986
The diagnosis and management of paroxysmal trigeminal neuralgia in association with a temporomandibular joint dysfunction.
    Oral surgery, oral medicine, and oral pathology, 1974, Volume: 38, Issue:6

    Topics: Arthritis, Rheumatoid; Autonomic Nerve Block; Carbamazepine; Dermatitis; Female; Humans; Indomethaci

1974
Diphenylhydantoin for steroid-induced muscle weakness.
    JAMA, 1973, Mar-12, Volume: 223, Issue:11

    Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Muscular Diseases; Phenytoin; Prednisolone

1973
Pentose-phosphate pathway of leucocytes.
    Acta haematologica, 1971, Volume: 46, Issue:1

    Topics: Adult; Aged; Alcoholism; Anemia, Aplastic; Arthritis, Rheumatoid; Asthma; Diabetes Mellitus; Female;

1971
[Vitamins and medicines. New and complicated relations].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Mar-30, Volume: 92, Issue:9

    Topics: Arthritis, Rheumatoid; Aspirin; Drug Combinations; Drug Interactions; Epilepsy; Humans; Phenytoin; P

1972