phenytoin has been researched along with Anxiety in 20 studies
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ro 5-4864, a selective ligand for the benzodiazepine micromolar and peripheral receptors, had a significant dose-related (5-20 mg/kg) anxiogenic action in the social interaction test of anxiety." | 3.66 | The anxiogenic action of Ro 5-4864 is reversed by phenytoin. ( File, SE; Lister, RG, 1983) |
| "Nortriptyline was reported in one study as superior for men with alcohol dependency on mean number of drinking days and on alcohol dependence, but not for severity of alcohol misuse or on the patient's or clinician's rating of drinking." | 2.46 | Pharmacological interventions for antisocial personality disorder. ( Duggan, C; Ferriter, M; Huband, N; Khalifa, N; Lieb, K; Stoffers, J; Völlm, BA, 2010) |
| "Phenytoin has two important properties that are advantageous for assessing the validity of the theta suppression model: 1) it is a standard antiepileptic drug with no known anxiolytic effects, and 2) its primary mechanism of action is through suppression of the persistent sodium current, an effect that should also suppress hippocampal theta." | 1.38 | A critical test of the hippocampal theta model of anxiolytic drug action. ( Dickson, CT; Treit, D; Yeung, M, 2012) |
| "Patient compliance can be improved by reducing the complexity of drug dosage and by better labeling, packaging and informational exchange." | 1.26 | Once-a-day drug regimen for psychiatric patients. ( Hasan, MK; Mooney, RP, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (70.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomczuk, BE | 1 |
| Taylor, CR | 1 |
| Moses, LM | 1 |
| Sutherland, DB | 1 |
| Lo, YS | 1 |
| Johnson, DN | 1 |
| Kinnier, WB | 1 |
| Kilpatrick, BF | 1 |
| Khalifa, NR | 1 |
| Gibbon, S | 1 |
| Völlm, BA | 2 |
| Cheung, NH | 1 |
| McCarthy, L | 1 |
| Khalifa, N | 1 |
| Duggan, C | 1 |
| Stoffers, J | 1 |
| Huband, N | 1 |
| Ferriter, M | 1 |
| Lieb, K | 1 |
| Garg, A | 1 |
| Agarwal, A | 1 |
| Jiloha, RC | 1 |
| Yeung, M | 1 |
| Treit, D | 1 |
| Dickson, CT | 1 |
| Hasan, MK | 1 |
| Mooney, RP | 1 |
| File, SE | 1 |
| Lister, RG | 1 |
| Freed, ED | 1 |
| Warneke, LB | 1 |
| Altshuler, LL | 1 |
| Devinsky, O | 1 |
| Post, RM | 1 |
| Theodore, W | 1 |
| Stephens, JH | 1 |
| Shaffer, JW | 1 |
| Friedman, AP | 1 |
| Hogg, PS | 1 |
| Covi, L | 1 |
| Lipman, RS | 1 |
| Pattison, JH | 1 |
| Derogatis, LR | 1 |
| Uhlenhuth, EH | 1 |
| Babington, RG | 1 |
| Horovitz, ZP | 1 |
| Overall, JE | 1 |
| Brown, D | 1 |
| Williams, JD | 1 |
| Neill, LT | 1 |
| Malitz, S | 1 |
| Kanzler, M | 1 |
| Howell, MC | 1 |
| Rever, GW | 1 |
| Scholl, ML | 1 |
| Trowbridge, F | 1 |
| Rutledge, A | 1 |
| Jonas, AD | 1 |
| Monroe, RR | 1 |
| Kramer, MD | 1 |
| Goulding, R | 1 |
| Wise, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Fluoxetine on Measures of Domestic Violence[NCT00011765] | Phase 2 | 104 participants (Actual) | Interventional | 2001-02-22 | Completed | ||
| Medication Development for Cocaine Dependence[NCT00249691] | Phase 3 | 180 participants (Anticipated) | Interventional | 2005-10-31 | Active, not recruiting | ||
| Monitoring of Seizures, EEG and Serum Antiepileptic Drug Concentrations in Patients With Uncontrolled Epilepsy[NCT00001149] | 900 participants | Observational | 1975-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for phenytoin and Anxiety
| Article | Year |
|---|---|
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2020 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2020 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2020 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2020 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2010 |
4 trials available for phenytoin and Anxiety
| Article | Year |
|---|---|
A controlled study of the effects of diphenylhydantoin on anxiety, irritability, and anger in neurotic outpatients.
Topics: Anger; Anxiety; Clinical Trials as Topic; Hostility; Humans; MMPI; Neurotic Disorders; Phenytoin; Ps | 1970 |
Length of treatment with anxiolytic sedatives and response to their sudden withdrawal.
Topics: Adolescent; Adult; Aged; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Drug Tolerance; Female | 1973 |
Drug treatment of anxiety and depression in detoxified alcoholic patients.
Topics: Alcoholism; Amitriptyline; Analysis of Variance; Anxiety; Ascorbic Acid; Chlordiazepoxide; Depressio | 1973 |
Are antidepressants better than placebo?
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Clinical Trials as | 1971 |
14 other studies available for phenytoin and Anxiety
| Article | Year |
|---|---|
2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as non-benzodiazepine anticonvulsants and anxiolytics.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Binding, Competitive; Cereb | 1991 |
Phenytoin dependence syndrome: a case report.
Topics: Adult; Anticonvulsants; Anxiety; Humans; Male; Phenytoin; Substance-Related Disorders | 2010 |
A critical test of the hippocampal theta model of anxiolytic drug action.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Biophysics; Diazepam; Disease Models, A | 2012 |
Once-a-day drug regimen for psychiatric patients.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Depressive Disorder; Drug Administratio | 1981 |
The anxiogenic action of Ro 5-4864 is reversed by phenytoin.
Topics: Animals; Anxiety; Benzodiazepinones; Humans; Interpersonal Relations; Isoquinolines; Male; Motor Act | 1983 |
The drug management of acute behavioural disturbances.
Topics: Acting Out; Acute Disease; Adrenergic beta-Antagonists; Aged; Antidepressive Agents, Tricyclic; Anti | 1975 |
A case of temporal lobe epilepsy with an orgasmic component.
Topics: Adult; Anxiety; Depression; Dominance, Cerebral; Epilepsy, Temporal Lobe; Functional Laterality; Hal | 1976 |
Depression, anxiety, and temporal lobe epilepsy. Laterality of focus and symptoms.
Topics: Adult; Analysis of Variance; Anxiety; Carbamazepine; Depression; Epilepsy, Temporal Lobe; Female; Fu | 1990 |
An overview of chronic recurring headache.
Topics: Acute Disease; Analgesics; Antidepressive Agents; Anxiety; Chronic Disease; Cortisone; Diuretics; Er | 1972 |
Three cases of 'restless legs' or 'Ekbom's syndrome' as seen in general practice.
Topics: Adult; Aged; Anxiety; Depression; Female; Humans; Leg; Male; Middle Aged; MMPI; Movement Disorders; | 1972 |
Neuropharmacology of SQ 10,996, a compound with several therapeutic indications.
Topics: Amides; Animals; Anticonvulsants; Antidepressive Agents; Anxiety; Behavior, Animal; Carbamazepine; C | 1973 |
Hyperactivity in children: types, diagosis, drug therapy, approaches to management.
Topics: Amphetamine; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chroni | 1972 |
Diphenylhydantoin and the treatment of anxiety.
Topics: Anxiety; Humans; Phenytoin | 1969 |
EFG activation of patients receiving phenothiazines and chlordiazepoxide.
Topics: Adult; Anxiety; Cerebral Cortex; Chloralose; Chlordiazepoxide; Chlorpromazine; Depression; Electroen | 1965 |