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phenytoin and Antibody Deficiency Syndrome

phenytoin has been researched along with Antibody Deficiency Syndrome in 18 studies

Research Excerpts

ExcerptRelevanceReference
"Phenobarbital may cause hyperactivity, behavioral problems, sedation, and even dementia; these effects are dose related to some extent."5.27Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy. ( Iivanainen, M; Savolainen, H, 1983)
"We report a patient who, 3 weeks after initiation of therapy, experienced a hypersensitivity reaction to phenytoin manifested as rash, lymphadenopathy, elevated serum transaminase levels, and subsequent panhypogammaglobulinemia with IgG, 180 mg/dl (control range 639 to 1349); IgA, 15 mg/dl (control range 70 to 312); and IgM, 0 mg/dl (control range 56 to 352)."3.67Permanent intrinsic B cell immunodeficiency caused by phenytoin hypersensitivity. ( Fawcett, WA; Guerra, IC; Lawrence, EC; Redmon, AH; Rosenblatt, HM; Shearer, WT, 1986)
"Phenobarbital may cause hyperactivity, behavioral problems, sedation, and even dementia; these effects are dose related to some extent."1.27Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy. ( Iivanainen, M; Savolainen, H, 1983)
" Maternal Balb/c mice were dosed by gavage on gestation days 9 through 18 with 0, 20, 40, or 60 mg/kg DPH."1.27Humoral immune dysfunction as a result of prenatal exposure to diphenylhydantoin: correlation with the occurrence of physical defects. ( Chapman, JR; Roberts, DW, 1984)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199017 (94.44)18.7374
1990's1 (5.56)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iivanainen, M1
Savolainen, H1
Chapman, JR1
Roberts, DW1
Dosch, HM1
Jason, J1
Gelfand, EW1
Vellucci, A1
Galanti, G1
Pezzella, B1
De Longis, P1
Colacecchi, C1
Lazoglu, AH1
Boglioli, LR1
Dorsett, B1
Macris, NT1
Seager, J1
Jamison, DL1
Wilson, J1
Hayward, AR1
Soothill, JF1
Masi, M1
Paolucci, P1
Perocco, P1
Franceschi, C1
Kanoh, T1
Uchino, H1
Shakir, RA1
Behan, PO1
Dick, H1
Lambie, DG1
Ikeda, T1
Higashi, A1
Matsuda, I1
Miyoshino, S1
Yabuki, S1
Nakaya, K1
Miuller, NR1
Tsyrlina, EV1
Ostroumova, MN1
Shemerovskaia, TG1
Aarli, JA1
Guerra, IC1
Fawcett, WA1
Redmon, AH1
Lawrence, EC1
Rosenblatt, HM1
Shearer, WT1
Ray, A1
Arora, S1
Plaut, AG1
Rocklin, RE1
Ambs, E1
Easton, JD1
Hennemann, G1
Docter, R1
Dolman, A1

Reviews

1 review available for phenytoin and Antibody Deficiency Syndrome

ArticleYear
[Lymphocyte culture and its relation to clinical problems].
    Klinische Wochenschrift, 1969, Aug-01, Volume: 47, Issue:15

    Topics: Antibody Formation; Culture Techniques; Drug Hypersensitivity; gamma-Globulins; Humans; Immunity, Ce

1969

Other Studies

17 other studies available for phenytoin and Antibody Deficiency Syndrome

ArticleYear
Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 97

    Topics: Abnormalities, Drug-Induced; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Endocrine Syst

1983
Humoral immune dysfunction as a result of prenatal exposure to diphenylhydantoin: correlation with the occurrence of physical defects.
    Teratology, 1984, Volume: 30, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Antibodies, Bacterial; Antibody Formation; Bacterial Infection

1984
Transient antibody deficiency and abnormal T suppressor cells induced by phenytoin.
    The New England journal of medicine, 1982, 02-18, Volume: 306, Issue:7

    Topics: Agammaglobulinemia; Child; Humans; Immunoglobulins; Immunologic Deficiency Syndromes; Male; Phenytoi

1982
[Case of "exanthematous pseudolymphoma" due to diphenylhydantoin hypersensitivity with a transitory immunologic deficit].
    La Clinica terapeutica, 1980, Jul-31, Volume: 94, Issue:2

    Topics: Adolescent; Drug Hypersensitivity; Exanthema; Humans; Immunologic Deficiency Syndromes; Lymphoma; Ma

1980
Phenytoin-related immunodeficiency associated with Loeffler's syndrome.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1995, Volume: 74, Issue:6

    Topics: Adult; Female; Humans; Hypersensitivity, Delayed; Immunologic Deficiency Syndromes; Phenytoin; Pulmo

1995
IgA deficiency, epilepsy, and phenytoin treatment.
    Lancet (London, England), 1975, Oct-04, Volume: 2, Issue:7936

    Topics: Adolescent; Cell Membrane; Child; Child, Preschool; Epilepsy; Female; Humans; IgA Deficiency; Immuno

1975
Letter: Immunosuppression by phenytoin.
    Lancet (London, England), 1976, Apr-17, Volume: 1, Issue:7964

    Topics: Child, Preschool; Dysgammaglobulinemia; Epilepsy; Humans; Immunoglobulin A; Immunologic Deficiency S

1976
Letter: Immunodeficiency and epilepsy.
    Lancet (London, England), 1976, Apr-17, Volume: 1, Issue:7964

    Topics: Adolescent; Adult; Agammaglobulinemia; Autoimmune Diseases; Child; Dysgammaglobulinemia; Epilepsy; H

1976
Metabolism of immunoglobulin A, lymphocyte function, and histocompatibility antigens in patients on anticonvulsants.
    Journal of neurology, neurosurgery, and psychiatry, 1978, Volume: 41, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Proteins; Epilepsy; Female; Folic Acid; HLA Antigens; Humans; Immunol

1978
Response to transfer factor to immunodeficiency in handicaps treated with phenytoin.
    European journal of pediatrics, 1979, Volume: 132, Issue:1

    Topics: Adolescent; Child; Female; Humans; Immunologic Deficiency Syndromes; Male; Phenytoin; Transfer Facto

1979
Immunoglobulin abnormalities in epileptic patients treated with diphenylhydantoin.
    Folia psychiatrica et neurologica japonica, 1976, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Dysgammaglobulinemia; Epilepsy; Female; Humans; Immunoglobulin A; Im

1976
[The effect of diphenine on the growth and metastasis of experimental malignant tumors].
    Voprosy onkologii, 1975, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Female; Immunologic

1975
[Drug induced IgA deficiency in epilepsy].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Feb-28, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Child; Dysgammaglobulinemia; Epilepsy; Humans; Immunoglobulin A; Immunologic Defi

1976
Permanent intrinsic B cell immunodeficiency caused by phenytoin hypersensitivity.
    The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:4

    Topics: Adult; Agammaglobulinemia; Antibodies, Monoclonal; B-Lymphocytes; Drug Hypersensitivity; Epilepsy, P

1986
Sustained B-lymphocyte immunodeficiency attributed to phenytoin therapy.
    The Journal of allergy and clinical immunology, 1987, Volume: 80, Issue:5

    Topics: Adolescent; B-Lymphocytes; Humans; Immunologic Deficiency Syndromes; Male; Phenytoin

1987
Potential hazards of hydantoin use.
    Annals of internal medicine, 1972, Volume: 77, Issue:6

    Topics: Epilepsy; Female; Humans; Immunity, Cellular; Immunoglobulins; Immunologic Deficiency Syndromes; Phe

1972
Relationship between total thyroxine and absolute free thyroxine and the influence of absolute free thyroxine on thyroxine disposal in humans.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:1

    Topics: Adult; Child; Female; Humans; Immunologic Deficiency Syndromes; Iodine Isotopes; Male; Pedigree; Phe

1971