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phenytoin and Anoxia, Fetal

phenytoin has been researched along with Anoxia, Fetal in 9 studies

Research Excerpts

ExcerptRelevanceReference
"There is evidence that drug-induced embryonic arrhythmia initiates phenytoin (PHT) teratogenicity."3.71Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs? ( Azarbayjani, F; Danielsson, BR, 2002)
"The aim of this study was to test the effect of supranutritional dosage of the natural antioxidant vitamin E (VitE) on phenytoin (PHT) induced developmental toxicity and possible long-term effects in rat offspring."1.33Vitamin E supplementation in phenytoin induced developmental toxicity in rats: postnatal study. ( Dubovický, M; Kovacovský, P; Mach, M; Navarová, J; Ujházy, E, 2006)
" Pharmacokinetic data correlated well with pregnancy outcome data."1.31Pharmacokinetic data support pharmacologically induced embryonic dysrhythmia as explanation to Fetal Hydantoin Syndrome in rats. ( Azarbayjani, F; Danielsson, B; Ohman, I; Sköld, AC; Webster, W, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's3 (33.33)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Webster, WS1
Howe, AM1
Abela, D1
Oakes, DJ1
Mach, M1
Dubovický, M1
Navarová, J1
Kovacovský, P1
Ujházy, E1
Harned, HS1
Lampley, EC1
Mishra, OP1
Graham, E1
Delivoria-Papadopoulos, M1
Danielsson, B1
Sköld, AC1
Azarbayjani, F2
Ohman, I1
Webster, W1
Danielsson, BR3
Teramo, K1
Hiilesmaa, V1
Bardy, A1
Saarikoski, S1
Danielson, MK1
Marchner, H1
Lundin, M1
Rundqvist, E2
Reiland, S2
Danielson, M1

Reviews

2 reviews available for phenytoin and Anoxia, Fetal

ArticleYear
The relationship between cleft lip, maxillary hypoplasia, hypoxia and phenytoin.
    Current pharmaceutical design, 2006, Volume: 12, Issue:12

    Topics: Animals; Anticonvulsants; Cleft Lip; Female; Fetal Hypoxia; Humans; Maxilla; Organogenesis; Phenytoi

2006
Cardiovascular problems of the newborn and their etiologies.
    Progress in clinical and biological research, 1983, Volume: 140

    Topics: Amphetamines; Animals; Cardiovascular Diseases; Estrogens; Ethanol; Female; Fetal Hypoxia; Heart Def

1983

Other Studies

7 other studies available for phenytoin and Anoxia, Fetal

ArticleYear
Vitamin E supplementation in phenytoin induced developmental toxicity in rats: postnatal study.
    Neuro endocrinology letters, 2006, Volume: 27 Suppl 2

    Topics: Animals; Animals, Newborn; Dietary Supplements; Female; Fetal Hypoxia; Fetal Viability; Growth and D

2006
Neuroprotective effect of phenytoin against in utero hypoxic brain injury in fetal guinea pigs.
    Neuroscience letters, 1995, Feb-17, Volume: 186, Issue:2-3

    Topics: Animals; Cell Membrane; Chromatography, High Pressure Liquid; Female; Fetal Hypoxia; Guinea Pigs; Hy

1995
Pharmacokinetic data support pharmacologically induced embryonic dysrhythmia as explanation to Fetal Hydantoin Syndrome in rats.
    Toxicology and applied pharmacology, 2000, Mar-01, Volume: 163, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Arrhythmias, Cardiac; Culture Techniques; Dose-Response Relati

2000
Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs?
    Epilepsia, 2002, Volume: 43, Issue:5

    Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Anticonvulsants; Arrhythmias, Cardiac; Cation Tra

2002
Fetal heart rate during a maternal grand mal epileptic seizure.
    Journal of perinatal medicine, 1979, Volume: 7, Issue:1

    Topics: Adult; Epilepsy, Tonic-Clonic; Female; Fetal Heart; Fetal Hypoxia; Fetal Monitoring; Heart Rate; Hum

1979
Histopathological and hemodynamic studies supporting hypoxia and vascular disruption as explanation to phenytoin teratogenicity.
    Teratology, 1992, Volume: 46, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Facial Bones; Female; Fetal Hypoxia; Gestational Age; Heart Ra

1992
Identical phalangeal defects induced by phenytoin and nifedipine suggest fetal hypoxia and vascular disruption behind phenytoin teratogenicity.
    Teratology, 1992, Volume: 45, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Blood Vessels; Female; Fetal Hypoxia; Gestational Age; Heart R

1992