Compounds > phenytoin
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phenytoin and Anemia, Aplastic

phenytoin has been researched along with Anemia, Aplastic in 30 studies

Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.

Research Excerpts

ExcerptRelevanceReference
"Rare, serious adverse effects of antiepileptic drugs (AEDs) include hepatotoxicity and bone marrow suppression."2.38Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy. ( Wyllie, E; Wyllie, R, 1991)
"Aplastic anemia is rare in SLE and the response to immunosuppressants is variable, but here is a success story."1.32Aplastic anemia complicating systemic lupus erythematosus: successful management with cyclosporine. ( Agarwal, SK; Garg, D; Kubba, S; Makhija, A; Pathania, A; Prakash, A; Prakash, N; Singh, NP, 2004)
"A 53-yr-old man sequentially developed aplastic anemia from phenytoin and carbamazepine."1.27Anticonvulsant-induced aplastic anemia: increased susceptibility to toxic drug metabolites in vitro. ( Fine, DG; Gerson, WT; Sensenbrenner, LL; Spielberg, SP, 1983)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199027 (90.00)18.7374
1990's1 (3.33)18.2507
2000's2 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DAWSON, JJ1
ISAACSON, S1
GOLD, JA1
GINSBERG, V1
Singh, NP1
Prakash, A1
Garg, D1
Makhija, A1
Pathania, A1
Prakash, N1
Kubba, S1
Agarwal, SK1
SPARBERG, M1
BRITTINGHAM, TE1
LUTCHER, CL1
MURPHY, DL1
DOAN, CA1
PANTAROTTO, MF1
Gerson, WT1
Fine, DG1
Spielberg, SP1
Sensenbrenner, LL1
Sugimoto, M1
Wakabayashi, Y1
Shiokawa, Y1
Takaku, F1
Hotta, T1
Hirabayashi, N1
Kobayashi, T1
Nakamura, S1
Suzuki, Y1
Blain, H1
Hamdan, KA1
Blain, A1
Jeandel, C1
Huijgens, PC1
Thijs, LG1
den Ottolander, GJ1
Geary, CG1
Pritchard, KI1
Quirt, IC1
Simpson, WJ1
Fleming, JF1
Ohno, Y1
Sato, M1
Kurokawa, I1
Moriyama, Y1
Kinoshita, Y1
Hausmann, K2
Skrandies, G2
Sachtleben, P2
Pisciotta, AV2
Wyllie, E1
Wyllie, R1
Ramsay, RE1
Tomita, S1
Kurokawa, T1
Ueda, K1
Higuchi, S1
Jeong, YG1
Jung, Y1
River, GL1
Yunis, AA1
Muller, C1
Ganzoni, AM1
Markkanen, T1
Peltola, O1
Davis, DG1
Smith, JL1
Recker, RR1
Hynes, HE1
Dameshek, W1

Reviews

6 reviews available for phenytoin and Anemia, Aplastic

ArticleYear
DIAGNOSTICALLY CONFUSING COMPLICATIONS OF DIPHENYLHYDANTOIN THERAPY. A REVIEW.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Adrenal Insufficiency; Anemia; Anemia, Aplastic; Anemia, Macrocytic; Conjunctivitis; Electrocardiogr

1963
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
    Epilepsia, 1991, Volume: 32 Suppl 5

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monit

1991
Use of phenytoin and carbamazepine in treatment of epilepsy.
    Neurologic clinics, 1986, Volume: 4, Issue:3

    Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognitio

1986
Idiosyncratic hematologic reactions to drugs.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Aspir

1974
Drug--induced bone marrow injury.
    Advances in internal medicine, 1969, Volume: 15

    Topics: Adult; Agranulocytosis; Anemia, Aplastic; Bone Marrow Diseases; Child, Preschool; Chloramphenicol; H

1969
[Acquired aplastic anemia, with special consideration of complications and prognosis].
    Schweizerische medizinische Wochenschrift, 1970, Mar-07, Volume: 100, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anemia, Aplastic; Blood Cell Count; Carbutamide; Chloramphenic

1970

Other Studies

24 other studies available for phenytoin and Anemia, Aplastic

ArticleYear
Fatal aplastic anaemia in a patient receiving epanutin (dilantin).
    King's College Hospital gazette, 1947, Volume: 26, Issue:3

    Topics: Anemia, Aplastic; Humans; Phenytoin

1947
Fatal aplastic anemia after therapy with nuvarone (3-methyl-5-phenylhydantoin).
    Journal of the American Medical Association, 1956, Apr-14, Volume: 160, Issue:15

    Topics: Anemia; Anemia, Aplastic; Humans; Hydantoins; Phenytoin

1956
Aplastic anemia complicating systemic lupus erythematosus: successful management with cyclosporine.
    Rheumatology international, 2004, Volume: 24, Issue:1

    Topics: Adult; Anemia, Aplastic; Cyclophosphamide; Cyclosporine; Female; Humans; Lupus Erythematosus, System

2004
REVERSIBLE ERYTHROID APLASIA INDUCED BY DIPHENYLHYDANTOIN.
    Archives of internal medicine, 1964, Volume: 113

    Topics: Adolescent; Anemia; Anemia, Aplastic; Black People; Blood Transfusion; Bone Marrow Examination; Huma

1964
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
    Postgraduate medicine, 1964, Volume: 35

    Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Coba

1964
[A CASE OF TRANSITORY MEDULLARY APLASIA IN A NEWBORN DUE TO ANTICONVULSANT DRUGS ADMINISTERED TO THE MOTHER DURING THE ENTIRE PREGNANCY].
    La Clinica ostetrica e ginecologica, 1965, Volume: 67

    Topics: Anemia; Anemia, Aplastic; Anticonvulsants; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mothe

1965
Anticonvulsant-induced aplastic anemia: increased susceptibility to toxic drug metabolites in vitro.
    Blood, 1983, Volume: 61, Issue:5

    Topics: Anemia, Aplastic; Carbamazepine; Female; Humans; Lymphocytes; Male; Microsomes; Middle Aged; Mutatio

1983
[Bone marrow heme synthesis suppression by diphenylhydantoin in vitro in pure red cell aplasia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1982, Volume: 23, Issue:9

    Topics: Anemia, Aplastic; Bone Marrow; Hemeproteins; Humans; Male; Middle Aged; Phenytoin

1982
[5 cases showing hemoglobinuria and aplastic crisis following administration of diphenylhydantoin after craniotomy (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1980, Volume: 21, Issue:4

    Topics: Adult; Aged; Anemia, Aplastic; Craniotomy; Female; Hemoglobinuria; Humans; Middle Aged; Phenytoin; P

1980
Aplastic anemia induced by phenytoin: a geriatric case with severe folic acid deficiency.
    Journal of the American Geriatrics Society, 2002, Volume: 50, Issue:2

    Topics: Aged; Anemia, Aplastic; Anticonvulsants; Folic Acid Deficiency; Humans; Male; Phenytoin; Pneumonia

2002
Pure red cell aplasia, toxic dermatitis and lymphadenopathy in a patient taking diphenylhydantoin.
    Acta haematologica, 1978, Volume: 59, Issue:1

    Topics: Adolescent; Anemia, Aplastic; Drug Eruptions; Female; Humans; Lymphatic Diseases; Phenytoin; Time Fa

1978
The pathogenesis of aplastic anaemia.
    British journal of hospital medicine, 1979, Volume: 21, Issue:4

    Topics: Adolescent; Anemia, Aplastic; Autoimmune Diseases; Benzene; Child; Chloramphenicol; Chlorpromazine;

1979
Phenytoin-associated reversible red cell aplasia.
    Canadian Medical Association journal, 1979, Dec-08, Volume: 121, Issue:11

    Topics: Adult; Anemia, Aplastic; Female; Humans; Phenytoin

1979
[Drug-induced erythroid aplasia-patient summary and pathogenetic mechanism].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1976, Volume: 17, Issue:1

    Topics: Adult; Anemia, Aplastic; Anti-Bacterial Agents; Female; Humans; Male; Phenytoin; Thiamphenicol; Thio

1976
[Current aspects of iatrogenic lesions of the bone marrow].
    Minerva medica, 1976, Nov-14, Volume: 67, Issue:55

    Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Chloramphenicol;

1976
Hematologic toxicity of carbamazepine.
    Advances in neurology, 1975, Volume: 11

    Topics: Adult; Aged; Anemia, Aplastic; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Hu

1975
Aplastic anaemia induced by intravenous phenytoin and lidocaine administration.
    European journal of pediatrics, 1985, Volume: 144, Issue:2

    Topics: Adolescent; Anemia, Aplastic; Drug Therapy, Combination; Female; Humans; Lidocaine; Phenytoin

1985
[Present aspects of bone marrow lesions due to drugs (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Sep-20, Volume: 116, Issue:38

    Topics: Anemia, Aplastic; Bone Marrow Diseases; Chloramphenicol; Drug-Related Side Effects and Adverse React

1974
Pure RBC aplasia and diphenylhydantoin.
    JAMA, 1974, Jul-15, Volume: 229, Issue:3

    Topics: Acute Disease; Adult; Anemia, Aplastic; Bone Marrow Examination; Diagnosis, Differential; Female; He

1974
Pentose-phosphate pathway of leucocytes.
    Acta haematologica, 1971, Volume: 46, Issue:1

    Topics: Adult; Aged; Alcoholism; Anemia, Aplastic; Arthritis, Rheumatoid; Asthma; Diabetes Mellitus; Female;

1971
Periodic alternating nystagmus. A report of eight cases.
    American journal of ophthalmology, 1971, Volume: 72, Issue:4

    Topics: Adult; Aged; Albinism; Anemia, Aplastic; Anemia, Sickle Cell; Blindness; Demyelinating Diseases; Dia

1971
Carbamazepine (Tegretol).
    The Medical letter on drugs and therapeutics, 1968, Jun-28, Volume: 10, Issue:13

    Topics: Agranulocytosis; Anemia, Aplastic; Blood Platelet Disorders; Carbamazepine; Dibenzazepines; Hematolo

1968
Pure red blood cell aplasia associated with chlorpropamide therapy. Patient summary and review of the literature.
    Archives of internal medicine, 1969, Volume: 123, Issue:4

    Topics: Adolescent; Adult; Aminosalicylic Acids; Anemia, Aplastic; Aspirin; Barbiturates; Child; Child, Pres

1969
Chloramphenicol aplastic anemia in identical twins--a clue to pathogenesis.
    The New England journal of medicine, 1969, Jul-03, Volume: 281, Issue:1

    Topics: Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Chloramphenicol; Chlorpromazine; Diseases in Twins

1969