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phenytoin and Anasarca

phenytoin has been researched along with Anasarca in 30 studies

Research Excerpts

ExcerptRelevanceReference
"Purple glove syndrome is a rare and poorly understood complication of phenytoin use, occurring almost always with its intravenous formulation."7.81Purple glove syndrome occurring after oral administration of phenytoin in therapeutic doses: mechanism still a dilemma. ( Handa, R; Jain, RS; Kumar, S; Nagpal, K; Prakash, S, 2015)
"Purple glove syndrome is an uncommon but dreaded complication of intravenous phenytoin administration characterised by pain, oedema and purple-blue discolouration of the limb distal to the site of injection."7.78Purple glove syndrome: a dreadful complication of intravenous phenytoin administration. ( Garg, RK; Lalla, R; Malhotra, HS; Sahu, R, 2012)
"Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb."7.74Purple glove syndrome following intravenous phenytoin administration. ( Chokshi, R; Mehta, NN; Mohler, E; Openshaw, J, 2007)
"A 71-year-old male with history of epilepsy was admitted for seizures and traumatic brain injury and intravenous fosphenytoin and levetiracetam were initiated."3.85Fosphenytoin-induced purple glove syndrome: A case report. ( Blunck, JR; Croom, JE; Fields, RK; Newman, JW, 2017)
"Purple glove syndrome is a rare and poorly understood complication of phenytoin use, occurring almost always with its intravenous formulation."3.81Purple glove syndrome occurring after oral administration of phenytoin in therapeutic doses: mechanism still a dilemma. ( Handa, R; Jain, RS; Kumar, S; Nagpal, K; Prakash, S, 2015)
"Purple glove syndrome is an uncommon but dreaded complication of intravenous phenytoin administration characterised by pain, oedema and purple-blue discolouration of the limb distal to the site of injection."3.78Purple glove syndrome: a dreadful complication of intravenous phenytoin administration. ( Garg, RK; Lalla, R; Malhotra, HS; Sahu, R, 2012)
"Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb."3.74Purple glove syndrome following intravenous phenytoin administration. ( Chokshi, R; Mehta, NN; Mohler, E; Openshaw, J, 2007)
"PGS is a poorly understood, potentially serious local complication of IV phenytoin administration characterized by progressive distal limb edema, discoloration, and pain."3.70Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin. ( Cascino, GD; Hanna, DR; O'Brien, TJ; So, EL, 1998)
"From April 8, 1982, through June 1984, 11 patients in a single hospital experienced 17 episodes of limb edema and discoloration after the intravenous (IV) administration of phenytoin sodium (Dilantin)."3.67Severe soft-tissue injury following intravenous infusion of phenytoin. Patient and drug administration risk factors. ( Arrowsmith, JB; Buchanan, C; Graham, DR; Kilarski, DJ; Spengler, RF; Von Behren, L, 1988)
"Phenytoin (PHT) has been widely used intravenously for the treatment of seizures since 1956, and for many years, it has been considered first-line therapy for status epilepticus."2.70A prospective study of the incidence of the purple glove syndrome. ( Anandan, JV; Barkley, GL; Burneo, JG, 2001)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199010 (33.33)18.7374
1990's3 (10.00)18.2507
2000's5 (16.67)29.6817
2010's12 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ulloora, S1
Shabaraya, R1
Ranganathan, R1
Adhikari, AV1
Tsang, CY1
Ng, JYW1
Yuen, SH1
Lau, IT1
Leung, YF1
Newman, JW1
Blunck, JR1
Fields, RK1
Croom, JE1
Ulubaş Işık, D1
Demirel, N1
Erol, S1
Ünal, S1
Baş, AY1
Jain, RS1
Nagpal, K1
Kumar, S1
Prakash, S1
Handa, R1
Shah, AM1
Dahodwala, A1
Abdel-Aziz, AA1
El-Azab, AS1
Abou-Zeid, LA1
ElTahir, KE1
Abdel-Aziz, NI1
Ayyad, RR1
Al-Obaid, AM1
Warnecke, IC1
Raute-Kreinsen, U1
Schirmer, S1
Kretschmer, F1
Fansa, H1
Chernoff, N1
Rogers, JM1
Prince, NJ1
Hill, C1
Wongkitisophon, P1
Chanprapaph, K1
Rattanakaemakorn, P1
Vachiramon, V1
Lalla, R1
Malhotra, HS1
Garg, RK1
Sahu, R1
Kirsch, S1
Bayard, M1
Darraj, K1
Chokshi, R1
Openshaw, J1
Mehta, NN1
Mohler, E1
Cadenbach, A1
Röttger, K1
Müller, MK1
O'Brien, TJ2
Cascino, GD1
So, EL1
Hanna, DR1
Coplin, WM1
Rhoney, DH1
Lyons, EA1
Murry, KR1
Yoshikawa, H1
Abe, T1
Oda, Y1
Burneo, JG1
Anandan, JV1
Barkley, GL1
Meara, FM1
Matthews, H1
Vajda, FJ1
Bosl, R1
Shideman, JR1
Meyer, RM1
Buselmeier, TJ1
von Hartitzsch, B1
Kjellstrand, CM1
Grinder, D1
Guastella, CP1
Pellegrino, M1
Spengler, RF1
Arrowsmith, JB1
Kilarski, DJ1
Buchanan, C1
Von Behren, L1
Graham, DR1
Robinson, HM1
Stone, JH1
Chikhani, P1
Mick, BA1
Nakamura, H2
Nakatsuji, K2
Nakamura, K2
Bianchi, C1
Bonardi, G1
Kadokawa, T1
Roberts, HJ1

Reviews

1 review available for phenytoin and Anasarca

ArticleYear
Hypoxia and the Edema Syndrome: elucidation of a mechanism of teratogenesis.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2010, Volume: 89, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Blister; Chick Embryo; Cocaine; Edema; Epinephrine; Hematoma;

2010

Trials

2 trials available for phenytoin and Anasarca

ArticleYear
A prospective study of the incidence of the purple glove syndrome.
    Epilepsia, 2001, Volume: 42, Issue:9

    Topics: Aged; Anticonvulsants; Edema; Epilepsy; Female; Forearm; Hand; Humans; Incidence; Infusions, Intrave

2001
Prospective study of local cutaneous reactions in patients receiving IV phenytoin.
    Neurology, 2001, Oct-23, Volume: 57, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Contusions; Edema; Epilepsy; Female; Humans; Incide

2001

Other Studies

27 other studies available for phenytoin and Anasarca

ArticleYear
Synthesis, anticonvulsant and anti-inflammatory studies of new 1,4-dihydropyridin-4-yl-phenoxyacetohydrazones.
    European journal of medicinal chemistry, 2013, Volume: 70

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Carrageenan; Disease Models, Anim

2013
Purple glove syndrome caused by intravenous phenytoin: two case reports.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2019, Volume: 25, Issue:6

    Topics: Administration, Intravenous; Aged, 80 and over; Anticonvulsants; Diagnosis, Differential; Edema; Fem

2019
Fosphenytoin-induced purple glove syndrome: A case report.
    Clinical neurology and neurosurgery, 2017, Volume: 160

    Topics: Aged; Anticonvulsants; Edema; Epilepsy; Humans; Male; Phenytoin; Skin Diseases; Upper Extremity

2017
A Rare Complication of Phenytoin Infusion in Newborn: Purple Glove Syndrome.
    Balkan medical journal, 2017, 12-01, Volume: 34, Issue:6

    Topics: Anticonvulsants; Cesarean Section; Cyanosis; Edema; Epilepsy, Tonic-Clonic; Humans; Infant, Newborn;

2017
Purple glove syndrome occurring after oral administration of phenytoin in therapeutic doses: mechanism still a dilemma.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:1

    Topics: Administration, Oral; Adult; Anticonvulsants; Cyanosis; Edema; Hand; Humans; Male; Phenytoin; Status

2015
Purple glove syndrome following intravenous phenytoin.
    Indian pediatrics, 2014, Volume: 51, Issue:9

    Topics: Edema; Forearm; Hand; Humans; Infant, Newborn; Phenytoin; Skin

2014
Synthesis, anti-inflammatory, analgesic and COX-1/2 inhibition activities of anilides based on 5,5-diphenylimidazolidine-2,4-dione scaffold: Molecular docking studies.
    European journal of medicinal chemistry, 2016, Jun-10, Volume: 115

    Topics: Analgesics; Anilides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase

2016
[Purple glove syndrome - a case report].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2010, Volume: 42, Issue:4

    Topics: Adult; Anticonvulsants; Edema; Endometriosis; Epilepsy, Complex Partial; Erythema; Extravasation of

2010
Purple glove syndrome following intravenous phenytoin administration.
    Archives of disease in childhood, 2011, Volume: 96, Issue:8

    Topics: Anticonvulsants; Child; Cyanosis; Edema; Female; Hand; Humans; Infusions, Intravenous; Phenytoin; St

2011
Six-year retrospective review of drug reaction with eosinophilia and systemic symptoms.
    Acta dermato-venereologica, 2012, Volume: 92, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Anti-HIV Agents; Anti-Inflammatory Agents; Anticonvulsa

2012
Purple glove syndrome: a dreadful complication of intravenous phenytoin administration.
    BMJ case reports, 2012, Aug-24, Volume: 2012

    Topics: Administration, Intravenous; Adult; Anticonvulsants; Drug Eruptions; Edema; Encephalitis; Fatal Outc

2012
Distal upper extremity edema and discoloration.
    American family physician, 2007, Mar-15, Volume: 75, Issue:6

    Topics: Aged; Arm; Diagnosis, Differential; Edema; Female; Humans; Hyperpigmentation; Injections, Intravenou

2007
Purple glove syndrome following intravenous phenytoin administration.
    Vascular medicine (London, England), 2007, Volume: 12, Issue:1

    Topics: Aged; Anticonvulsants; Cyanosis; Edema; Epilepsy, Tonic-Clonic; Hand; Humans; Infusions, Intravenous

2007
["Purple glove syndrome." Severe soft tissue reaction following phenytoin infusion].
    Deutsche medizinische Wochenschrift (1946), 1998, Mar-13, Volume: 123, Issue:11

    Topics: Adult; Anticonvulsants; Edema; Epilepsy, Tonic-Clonic; Female; Forearm; Humans; Inflammation; Infusi

1998
Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin.
    Neurology, 1998, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Edema; Female; Forearm; Hand; Hu

1998
Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin.
    Neurology, 1999, Oct-22, Volume: 53, Issue:7

    Topics: Anticonvulsants; Edema; Extremities; Humans; Injections, Intravenous; Pain; Phenytoin

1999
Purple glove syndrome caused by oral administration of phenytoin.
    Journal of child neurology, 2000, Volume: 15, Issue:11

    Topics: Administration, Oral; Anticonvulsants; Child; Drug Overdose; Edema; Epilepsy; Extremities; Humans; M

2000
Effects and complications of high efficiency dialysis.
    Nephron, 1975, Volume: 15, Issue:2

    Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypote

1975
Soft-tissue damage and intravenous phenytoin.
    Drug intelligence & clinical pharmacy, 1988, Volume: 22, Issue:9

    Topics: Aged; Diabetes Complications; Edema; Female; Humans; Injections, Intravenous; Phenytoin

1988
Severe soft-tissue injury following intravenous infusion of phenytoin. Patient and drug administration risk factors.
    Archives of internal medicine, 1988, Volume: 148, Issue:6

    Topics: Age Factors; Aged; Cardiovascular Diseases; Catheterization; Connective Tissue Diseases; Edema; Fema

1988
Exanthem due to diphenylhydantoin therapy.
    Archives of dermatology, 1970, Volume: 101, Issue:4

    Topics: Adolescent; Alkaline Phosphatase; Blood Chemical Analysis; Blood Urea Nitrogen; Drug Eruptions; Edem

1970
[Use of sodium phenytoin in the treatment of periodontal diseases].
    Actualites odonto-stomatologiques, 1972, Volume: 26, Issue:98

    Topics: Adult; Age Factors; Aged; Edema; Female; Gingival Hypertrophy; Humans; Male; Massage; Middle Aged; O

1972
Diphenylhydantoin and intermittent edema.
    JAMA, 1973, Sep-17, Volume: 225, Issue:12

    Topics: Adolescent; Edema; Female; Fingers; Humans; Leg; Phenytoin

1973
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. 3. Absorption, tissue distribution and metabolic fate.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:11

    Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Carrageenan; Chromatography, Thin Layer; Dogs; Ed

1970
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 3. General pharmacological properties.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Barbiturates; Blood Glucose; Cardiovascular System;

1972
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capill

1970
An inquiry into the pathogenesis, rational treatment and prevention of multiple sclerosis, with emphasis upon the combined role of diabetogenic hyperinsulinism and recurrent edema.
    Journal of the American Geriatrics Society, 1966, Volume: 14, Issue:6

    Topics: Adult; Diet Therapy; Edema; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Male; Methylphe

1966