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phenytoin and Amyotrophic Lateral Sclerosis

phenytoin has been researched along with Amyotrophic Lateral Sclerosis in 2 studies

Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anger, T1
Madge, DJ1
Mulla, M1
Riddall, D1
Cordonnier, M1
Delwaide, PJ1

Reviews

1 review available for phenytoin and Amyotrophic Lateral Sclerosis

ArticleYear
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Mo

2001

Other Studies

1 other study available for phenytoin and Amyotrophic Lateral Sclerosis

ArticleYear
[Malignant and benign fasciculations. Apropos of a case of neuromyotonia].
    Revue medicale de Liege, 1979, Oct-15, Volume: 34, Issue:20

    Topics: Amyotrophic Lateral Sclerosis; Electromyography; Fasciculation; Female; Humans; Middle Aged; Movemen

1979