phenytoin has been researched along with Alzheimer Disease in 5 studies
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures were generalized tonic-clonic in type and were unassociated with clinical or (in 3 subjects) neuropathologic evidence for epileptogenic factors other than Alzheimer's disease." | 1.28 | Advanced Alzheimer's disease is a risk factor for late-onset seizures. ( Ashkin, K; Coben, LA; Morris, JC; Romanelli, MF, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhikav, V | 1 |
| Jaseja, H | 1 |
| Carter, MD | 1 |
| Weaver, DF | 1 |
| Joudrey, HR | 1 |
| Carter, AO | 1 |
| Rockwood, K | 1 |
| Auchus, AP | 1 |
| Freeman, A | 1 |
| Green, RC | 1 |
| Romanelli, MF | 1 |
| Morris, JC | 1 |
| Ashkin, K | 1 |
| Coben, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Levetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial (LAPSE) - A Phase II Exploratory Study[NCT04004702] | Phase 2 | 65 participants (Anticipated) | Interventional | 2020-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for phenytoin and Alzheimer Disease
| Article | Year |
|---|---|
Can phenytoin prevent Alzheimer's disease?
Topics: Alzheimer Disease; Anticonvulsants; Hippocampus; Humans; Models, Biological; Phenytoin | 2006 |
Does phenytoin play any role in prevention of Alzheimer's disease?
Topics: Alzheimer Disease; Anticonvulsants; Hippocampus; Humans; Phenytoin | 2007 |
Epilepsy and antiepileptic drug use in elderly people as risk factors for dementia.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Anticonvulsants; Cohort Studies; Epilepsy; Female | 2007 |
Agitated behavior relieved following treatment of cervical dystonia in dementia.
Topics: Alzheimer Disease; Botulinum Toxins; Chlorpromazine; Dystonia; Female; Humans; Isoxazoles; Middle Ag | 1995 |
Advanced Alzheimer's disease is a risk factor for late-onset seizures.
Topics: Aged; Alzheimer Disease; Confounding Factors, Epidemiologic; Electroencephalography; Female; Humans; | 1990 |