phenytoin has been researched along with Allergy, Drug in 206 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenytoin hypersensitivity syndrome (PHS) is a rare delayed hypersensitivity reaction which occurs following exposure to phenytoin sodium." | 8.79 | Bronchiolitis obliterans with organizing pneumonia and cold agglutinin disease associated with phenytoin hypersensitivity syndrome. ( Angle, P; Chiu, B; Freedman, J; Thomas, P, 1997) |
| "The clinical manifestations of the phenytoin hypersensitivity syndrome are reviewed." | 8.77 | Phenytoin hypersensitivity syndrome. ( Araujo, OE; Flowers, FP; Hamm, KA, 1987) |
| "Phenytoin, one of the most common antiepileptic drugs, is a major cause of antiepileptic drug hypersensitivity syndrome (AHS), which is a rare but potentially fatal complication." | 7.75 | Agranulocytosis following phenytoin-induced hypersensitivity syndrome. ( Imai, K; Ito, S; Oguni, H; Osawa, M; Sasaki, K; Shioda, M, 2009) |
| "Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome associated with anticonvulsant drugs is a rare but potentially life-threatening disease that occurs in response to arene oxide producing anticonvulsant such as phenytoin and carbamazepine." | 7.73 | Drug hypersensitivity to previously tolerated phenytoin by carbamazepine-induced DRESS syndrome. ( Choi, GS; Kim, CW; Kim, DI; Yun, CH, 2006) |
| "We report a 30-year-old female with hypersensitivity syndrome (HS) due to phenytoin." | 7.71 | A case of hypersensitivity syndrome due to phenytoin. ( Hattori, T; Ishikawa, O; Nagai, Y, 2002) |
| "The purpose of the current manuscript is to familiarize the primary physician with the presentation of phenytoin hypersensitivity syndrome, and to discuss management options." | 7.69 | Phenytoin hypersensitivity syndrome. ( Carlton, FB; Sanders, DY; Thompson, JR, 1996) |
| "Four-year-old, 20-kg girl, diagnosed with idiopathic tonic-clonic epilepsy, who developed AHS to phenobarbital and phenytoin and status epilepticus unresponsive to lorazepam." | 7.68 | Diazepam by continuous intravenous infusion for status epilepticus in anticonvulsant hypersensitivity syndrome. ( Bertz, RJ; Howrie, DL, 1993) |
| "We report a life-threatening case of phenytoin hypersensitivity syndrome, a rare reaction primarily characterized by fever, skin eruptions, lymphadenopathy, eosinophilia, and hepatotoxicity." | 7.68 | Phenytoin hypersensitivity syndrome: a case report. ( Dunn, MI; Engen, PL; Howard, PA, 1991) |
| "A 38-year old woman receiving phenytoin (diphenylhydantoin) noticed maculopapular erythema as the first manifestation of a syndrome that included acute renal failure and myositis in addition to fever, lymphadenopathy, exfoliative dermatitis, and hepatitis." | 7.65 | Reversible renal failure and myositis caused by phenytoin hypersensitivity. ( Michael, JR; Mitch, WE, 1976) |
| "In vitro and in vivo immunologic studies were performed on a 28-year-old woman with phenytoin sodium-induced pseudolymphoma syndrome." | 7.65 | Phenytoin-induced pseudolymphoma syndrome: an immunologic study. ( Charlesworth, EN, 1977) |
| "When phenytoin was administered to rats (p." | 5.27 | Immunological studies on delayed hypersensitivity to phenytoin--II. The delayed skin reaction induced by BSA-phenytoin conjugate. ( Kamei, C; Miyake, H; Taska, K; Uokawa, M, 1987) |
| "These infections present frequently as postoperative fever and a change in sensorium." | 5.26 | Phenytoin hypersensitivity presenting as postoperative fever. ( Carpenter, J; Kendrick, M; Newby, N; Sander, G, 1980) |
| "The goals of this study were to determine if the use of phenytoin to prevent early posttraumatic seizures following head injury was associated with significant adverse side effects and also to determine if the reduction in early posttraumatic seizures after phenytoin administration was associated with a change in mortality rates in head-injured patients." | 5.09 | Side effects and mortality associated with use of phenytoin for early posttraumatic seizure prophylaxis. ( Dikmen, SS; Haltiner, AM; Newell, DW; Temkin, NR; Winn, HR, 1999) |
| "The antiepileptic drug hypersensitivity syndrome (AHS) is an adverse drug reaction associated with the aromatic antiepileptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), and primidone." | 4.80 | Antiepileptic drug hypersensitivity syndrome. ( Schlienger, RG; Shear, NH, 1998) |
| "Phenytoin hypersensitivity syndrome (PHS) is a rare delayed hypersensitivity reaction which occurs following exposure to phenytoin sodium." | 4.79 | Bronchiolitis obliterans with organizing pneumonia and cold agglutinin disease associated with phenytoin hypersensitivity syndrome. ( Angle, P; Chiu, B; Freedman, J; Thomas, P, 1997) |
| "Anticonvulsant hypersensitivity syndrome (AHS) is an uncommon but potentially fatal adverse effect that can occur from exposure to phenytoin, carbamazepine, or phenobarbital." | 4.79 | Anticonvulsant hypersensitivity syndrome. ( Miller, MB; Morkunas, AR, 1997) |
| "The clinical manifestations of the phenytoin hypersensitivity syndrome are reviewed." | 4.77 | Phenytoin hypersensitivity syndrome. ( Araujo, OE; Flowers, FP; Hamm, KA, 1987) |
| " With carbamazepine and phenytoin, hepatotoxicity may be due to drug hypersensitivity." | 4.77 | Hepatic considerations in the use of antiepileptic drugs. ( Dreifuss, FE; Langer, DH, 1987) |
| " All had dermatological manifestations, eosinophilia and systemic (haematological and hepatic) manifestations that could be attributed to treatment with aromatic AEDs (carbamazepine, 2 patients; lamotrigine, 3 patients; phenytoin, 3 patients)." | 3.77 | Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs. ( Kochen, S; Pereira de Silva, N; Piquioni, P; Saidon, P, 2011) |
| "Phenytoin, one of the most common antiepileptic drugs, is a major cause of antiepileptic drug hypersensitivity syndrome (AHS), which is a rare but potentially fatal complication." | 3.75 | Agranulocytosis following phenytoin-induced hypersensitivity syndrome. ( Imai, K; Ito, S; Oguni, H; Osawa, M; Sasaki, K; Shioda, M, 2009) |
| "Seven patients who presented with phenytoin-induced maculopapular exanthema with and without fever were included in this study." | 3.74 | Allergen-specific T-cell response in patients with phenytoin hypersensitivity; simultaneous analysis of proliferation and cytokine production by carboxyfluorescein succinimidyl ester (CFSE) dilution assay. ( Itomi, S; Kakami, M; Kawamura, M; Komatsubara, R; Kondo, Y; Nakajima, Y; Okumura, A; Tsuge, I; Urisu, A, 2007) |
| "A previous study conducted in Taiwan found a 100% association between HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome (SJS) in Han Chinese subjects, with an extremely high odds ratio compared with carbamazepine-tolerant subjects (odds ratio = 2,504)." | 3.74 | Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. ( Baum, L; Cheng, AS; Kwan, P; Lau, KM; Man, CB; Ng, MH; Yu, E, 2007) |
| "Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome associated with anticonvulsant drugs is a rare but potentially life-threatening disease that occurs in response to arene oxide producing anticonvulsant such as phenytoin and carbamazepine." | 3.73 | Drug hypersensitivity to previously tolerated phenytoin by carbamazepine-induced DRESS syndrome. ( Choi, GS; Kim, CW; Kim, DI; Yun, CH, 2006) |
| "Aromatic anticonvulsant agents such as carbamazepine and phenytoin can induce anticonvulsant hypersensitivity syndrome (AHS) at a frequency of 1 in 10,000 to 1 in 1,000 treated patients." | 3.73 | Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents. ( Bröcker, EB; Pfeuffer, P; Raith, P; Seitz, CS; Trautmann, A, 2006) |
| "We describe the case of a patient in whom anticonvulsant hypersensitivity syndrome developed during treatment with phenytoin and progressed when therapy was changed to phenobarbital." | 3.72 | Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin. ( Finch, CK; Jones, R; Mostella, J; Pieroni, R, 2004) |
| " The aim of this study was to study the frequency and nature of cutaneous reactions in a cohort of patients being treated with phenytoin sodium for seizures, who were divided into those with a solitary cysticercus granuloma (SCG) and those with a condition other than SCG, to determine if the presence of SCG increases the risk of cutaneous adverse reaction to phenytoin." | 3.72 | Cutaneous reactions in patients with solitary cysticercus granuloma on phenytoin sodium. ( Chander Chopra, S; Gupta, M; Kaushal, S; Singh, G, 2004) |
| "We report a 30-year-old female with hypersensitivity syndrome (HS) due to phenytoin." | 3.71 | A case of hypersensitivity syndrome due to phenytoin. ( Hattori, T; Ishikawa, O; Nagai, Y, 2002) |
| "Phenytoin hypersensitivity syndrome (PHS) is a rare, and important entity characterized by rash, fever, lymphadenopathy, leukocytosis with atypical lymphocytes, eosinophilia and associated hepatitis." | 3.71 | Phenytoin hypersensitivity syndrome. ( Alli, N; Cömcüoğlu, C; Comoğlu, S; Güngör, E, 2001) |
| "This is the report about a very early onset of phenytoin hypersensitivity reaction showing respiratory insufficiency, fever, hepatic and skin reactions in a 68-year-old male patient who was concomitantly treated with high dose dexamethasone/prednisolone because of brain edema." | 3.70 | Development of a pulmonary phenytoin-associated hypersensitivity reaction despite concomitant dexamethasone and prednisolone administration. ( Brandt, W; Röse, W; Tröger, U, 2000) |
| " the LTA by using trypan blue exclusion and to determine the utility of the assay to confirm drug hypersensitivity syndrome (DHS) to sulphonamides (SMX) and aromatic anticonvulsants." | 3.70 | A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes. ( Malkiewicz, IM; Neuman, MG; Shear, NH, 2000) |
| "The purpose of the current manuscript is to familiarize the primary physician with the presentation of phenytoin hypersensitivity syndrome, and to discuss management options." | 3.69 | Phenytoin hypersensitivity syndrome. ( Carlton, FB; Sanders, DY; Thompson, JR, 1996) |
| "Anticonvulsant hypersensitivity syndrome is a potentially fatal drug reaction with cutaneous and systemic reactions (incidence, one in 1000 to one in 10,000 exposures) to the arene oxide-producing anticonvulsants--phenytoin, carbamazepine, and phenobarbital sodium." | 3.69 | Anticonvulsant hypersensitivity syndrome. ( Muglia, JJ; Vittorio, CC, 1995) |
| "Four-year-old, 20-kg girl, diagnosed with idiopathic tonic-clonic epilepsy, who developed AHS to phenobarbital and phenytoin and status epilepticus unresponsive to lorazepam." | 3.68 | Diazepam by continuous intravenous infusion for status epilepticus in anticonvulsant hypersensitivity syndrome. ( Bertz, RJ; Howrie, DL, 1993) |
| "We report a life-threatening case of phenytoin hypersensitivity syndrome, a rare reaction primarily characterized by fever, skin eruptions, lymphadenopathy, eosinophilia, and hepatotoxicity." | 3.68 | Phenytoin hypersensitivity syndrome: a case report. ( Dunn, MI; Engen, PL; Howard, PA, 1991) |
| "We report a patient who, 3 weeks after initiation of therapy, experienced a hypersensitivity reaction to phenytoin manifested as rash, lymphadenopathy, elevated serum transaminase levels, and subsequent panhypogammaglobulinemia with IgG, 180 mg/dl (control range 639 to 1349); IgA, 15 mg/dl (control range 70 to 312); and IgM, 0 mg/dl (control range 56 to 352)." | 3.67 | Permanent intrinsic B cell immunodeficiency caused by phenytoin hypersensitivity. ( Fawcett, WA; Guerra, IC; Lawrence, EC; Redmon, AH; Rosenblatt, HM; Shearer, WT, 1986) |
| "A 71-year-old man had status epilepticus and was treated with phenytoin (Dilantin) sodium." | 3.66 | Fatal benign phenytoin lymphadenopathy. ( Aguilar, JC; McCarthy, LJ; Ransburg, R, 1979) |
| "The case of a 19-year-old patient is reported who during treatment with phenytoin (5,5-dephenylhydantoin) developed a Stevens-Johnson syndrome." | 3.65 | [Stevens-Johnson syndrome as an early allergic reaction to diphenylhydantoin]. ( Marg, E, 1976) |
| "In vitro and in vivo immunologic studies were performed on a 28-year-old woman with phenytoin sodium-induced pseudolymphoma syndrome." | 3.65 | Phenytoin-induced pseudolymphoma syndrome: an immunologic study. ( Charlesworth, EN, 1977) |
| "A 38-year old woman receiving phenytoin (diphenylhydantoin) noticed maculopapular erythema as the first manifestation of a syndrome that included acute renal failure and myositis in addition to fever, lymphadenopathy, exfoliative dermatitis, and hepatitis." | 3.65 | Reversible renal failure and myositis caused by phenytoin hypersensitivity. ( Michael, JR; Mitch, WE, 1976) |
| "Phenytoin is a prototypic drug prescribed for the treatment of a variety of seizure disorders." | 3.01 | Cutaneous Hypersensitivity Reaction After Phenytoin Therapy in a Neonate: A Case Report and Review of Literature Elucidating the Potential Pharmacological Plausibility and Preventive Strategies. ( Prabath, I; Rajendran, P; Rani, J, 2023) |
| " It can cause generalized cutaneous eruptions that include a maculopapular exanthem, Stevens-Johnson syndrome, generalized exfoliative dermatitis, toxic epidermal necrolysis, vasculitis, and fixed-drug eruptions." | 2.42 | Phenytoin in cutaneous medicine: its uses, mechanisms and side effects. ( Scheinfeld, N, 2003) |
| "Drug-induced fever is most commonly the result of a hypersensitivity reaction and its characteristics resemble those of an allergic reaction." | 2.37 | Drug-induced fever. ( Tabor, PA, 1986) |
| "She developed congestive heart failure, with a substantial reduction in ejection fraction (EF) by an echocardiogram and serum cardiac enzyme elevation." | 1.33 | Anticonvulsant hypersensitivity syndrome leading to reversible myocarditis. ( Zaidi, AN, 2005) |
| "This syndrome is accompanied by fever, rash, lymphadenopathy, eosinophilia and affects parenchymal organs." | 1.32 | [Anticonvulsant hypersensitivity syndrome]. ( Papp, Z; Török, L, 2004) |
| " In addition, there was a significant dose-response association between the development of procarbazine hypersensitivity and the presence of therapeutic anticonvulsant serum levels (p = 0." | 1.30 | Anticonvulsant usage is associated with an increased risk of procarbazine hypersensitivity reactions in patients with brain tumors. ( Coyle, TE; Hurteau, TE; Lehmann, DF; Newman, N, 1997) |
| "Phenytoin is a highly effective and widely prescribed anticonvulsant agent." | 1.30 | Anticonvulsant hypersensitivity syndrome occurring as sepsis with multiorgan dysfunction. ( Marik, P, 1999) |
| "Phenytoin was withdrawn and corticosteroid was started in therapeutic doses." | 1.29 | The role of gallium-67-citrate in the detection of phenytoin-induced pneumonitis. ( Brown, SJ; Dadparvar, S; Khan, AS; Krishna, L; Meihoffer, M; Roman, R; Slizofski, WJ, 1994) |
| "T cell analysis of patients with acute drug allergy to carbamazepine, phenytoin, allopurinol, or paracetamol confirms the in vitro data, because all patients had activated CD4+ or CD8+ T cells in the circulation." | 1.29 | Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine. ( Bettens, F; Brander, C; Hunziker, T; Mauri, D; Mauri-Hellweg, D; Pichler, WJ, 1995) |
| "Sorbinil is a hydantoin aldose reductase inhibitor that has shown promise as therapy for patients with diabetic complications such as neuropathy and retinopathy." | 1.28 | In-vitro assessment of a hypersensitivity syndrome associated with sorbinil. ( Cannon, M; Gunderson, K; Hutson, NJ; Shear, NH; Spielberg, SP, 1991) |
| "Hypersensitivity myocarditis is an inflammatory disease of the myocardium usually related to a drug allergy." | 1.27 | Myocarditis related to drug hypersensitivity. ( Lie, JT; Olney, BA; Taliercio, CP, 1985) |
| "We have reported a case of acute hypersensitivity pneumonitis, probably caused by phenytoin, in which the results of bronchoalveolar lavage suggested a predominantly lymphocytic type of alveolitis, comparable to the alveolitis of sarcoidosis or chronic hypersensitivity pneumonitis." | 1.27 | Bronchoalveolar lavage in acute drug-hypersensitivity pneumonitis probably caused by phenytoin. ( Baughman, RP; Bullock, WE; Munn, NJ; Ploysongsang, Y; Wirman, JA, 1984) |
| " DPH withdrawal induced a leftward displacement of the dose-response curves obtained for the convulsive effects of both picrotoxin and metrazol and decreased the latency of 3-mercaptopropionic acid-induced seizures." | 1.27 | Central nervous system supersensitivity and withdrawal from long-term diphenylhydantoin treatment. ( De-Lima, TC; Palermo-Neto, J, 1983) |
| "When phenytoin was administered to rats (p." | 1.27 | Immunological studies on delayed hypersensitivity to phenytoin--II. The delayed skin reaction induced by BSA-phenytoin conjugate. ( Kamei, C; Miyake, H; Taska, K; Uokawa, M, 1987) |
| "The laboratory findings revealed leukocytosis with atypical lymphocytes, eosinophilia and altered liver function." | 1.27 | [Hypersensitivity syndrome caused by phenytoins and phenobarbital]. ( Azulay, DR; Azulay, RD; Fonseca, JC; Rozembau, I, 1984) |
| "Phenytoin was discontinued after admission; however, phenytoin 1 g i." | 1.27 | Phenytoin-induced hypersensitivity reactions. ( Lander, RD; Prosser, TR, 1987) |
| "Acquired immunodeficiency syndrome (AIDS), with its attendant sequelae of opportunistic infections and aggressive lymphatic malignancies, continues to dominate the world's medical literature." | 1.27 | Phenytoin hypersensitivity with pulmonary involvement in a hemophiliac patient with human immunodeficiency virus infection. ( Amundson, D; Hostettler, C; O'Connor, S, 1987) |
| "These infections present frequently as postoperative fever and a change in sensorium." | 1.26 | Phenytoin hypersensitivity presenting as postoperative fever. ( Carpenter, J; Kendrick, M; Newby, N; Sander, G, 1980) |
| "Phenytoin alone was not toxic to cells." | 1.26 | Predisposition to phenytoin hepatotoxicity assessed in vitro. ( Blake, DA; Goldstein, DA; Gordon, GB; Herlong, HF; Spielberg, SP, 1981) |
| "A case of acute renal failure developing at two separate times after the use of diphenylhydantoin is described." | 1.26 | Diphenylhydantoin-induced acute renal failure. ( Agarwal, BN; Cabebe, FG; Hoffman, BI, 1977) |
| "The case of a patient who developed Hodgkin's disease three years after commencement of therapy with phenytoin is presented." | 1.25 | Phenytoin sensitivity in a case of phenytoin-associated Hodgkin's disease. ( Forbes, IJ; Sorrell, TC, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 113 (54.85) | 18.7374 |
| 1990's | 39 (18.93) | 18.2507 |
| 2000's | 40 (19.42) | 29.6817 |
| 2010's | 13 (6.31) | 24.3611 |
| 2020's | 1 (0.49) | 2.80 |
| Authors | Studies |
|---|---|
| Rajendran, P | 1 |
| Prabath, I | 1 |
| Rani, J | 1 |
| Su, SC | 1 |
| Chen, CB | 1 |
| Chang, WC | 1 |
| Wang, CW | 1 |
| Fan, WL | 1 |
| Lu, LY | 1 |
| Nakamura, R | 1 |
| Saito, Y | 2 |
| Ueta, M | 1 |
| Kinoshita, S | 1 |
| Sukasem, C | 1 |
| Yampayon, K | 1 |
| Kijsanayotin, P | 1 |
| Nakkam, N | 1 |
| Saksit, N | 1 |
| Tassaneeyakul, W | 1 |
| Aihara, M | 2 |
| Lin, YJ | 1 |
| Chang, CJ | 1 |
| Wu, T | 1 |
| Hung, SI | 1 |
| Chung, WH | 1 |
| Manuyakorn, W | 1 |
| Siripool, K | 1 |
| Kamchaisatian, W | 1 |
| Pakakasama, S | 1 |
| Visudtibhan, A | 1 |
| Vilaiyuk, S | 1 |
| Rujirawat, T | 1 |
| Benjaponpitak, S | 1 |
| Keel, BR | 1 |
| Payne, CL | 1 |
| Tamura, A | 1 |
| Miyawaki, I | 1 |
| Yamada, T | 2 |
| Kimura, J | 1 |
| Funabashi, H | 1 |
| Topcu, H | 1 |
| Gokcinar, D | 1 |
| Akcaboy, ZN | 1 |
| Karabeyoglu, I | 1 |
| Unal, T | 1 |
| Polat, I | 1 |
| Karaoglu, P | 1 |
| Ayanoglu, M | 1 |
| Yis, U | 1 |
| Hiz, S | 1 |
| Ito, S | 1 |
| Shioda, M | 1 |
| Sasaki, K | 1 |
| Imai, K | 1 |
| Oguni, H | 1 |
| Osawa, M | 1 |
| Yazicioglu, M | 1 |
| Mentes, DA | 1 |
| Turgut, B | 1 |
| Viera, MH | 1 |
| Perez, OA | 1 |
| Patel, JK | 1 |
| Jones, I | 1 |
| Berman, B | 1 |
| Pereira de Silva, N | 1 |
| Piquioni, P | 1 |
| Kochen, S | 1 |
| Saidon, P | 1 |
| Cantarín-Extremera, V | 1 |
| Castaño-De La Mota, C | 1 |
| Alvarez-Coca, J | 1 |
| Rojas, MR | 1 |
| Gutierrez-Solana, LG | 1 |
| García Peñas, JJ | 1 |
| Martínez-Pérez, J | 1 |
| Duat-Rodríguez, A | 1 |
| López-Marín, L | 1 |
| Losada-Del Pozo, R | 1 |
| Watanabe, H | 1 |
| Koide, R | 1 |
| Iijima, M | 1 |
| McCormack, M | 1 |
| Urban, TJ | 1 |
| Shianna, KV | 1 |
| Walley, N | 1 |
| Pandolfo, M | 1 |
| Depondt, C | 1 |
| Chaila, E | 1 |
| O'Conner, GD | 1 |
| Kasperavičiūtė, D | 1 |
| Radtke, RA | 1 |
| Heinzen, EL | 1 |
| Sisodiya, SM | 1 |
| Delanty, N | 1 |
| Cavalleri, GL | 1 |
| Siebert, WJ | 1 |
| McGavigan, AD | 1 |
| Harding, DJ | 1 |
| Subramaniam, K | 1 |
| MacQuillan, G | 1 |
| Davis, J | 1 |
| Nolan, D | 1 |
| Fujino, Y | 1 |
| Nakajima, M | 1 |
| Inoue, H | 1 |
| Kusuhara, T | 1 |
| Nagai, Y | 1 |
| Hattori, T | 1 |
| Ishikawa, O | 1 |
| Monks, G | 1 |
| Crowson, AN | 1 |
| Cornelison, R | 1 |
| Naylor, M | 1 |
| Scheinfeld, N | 2 |
| MELCHIOR, JC | 1 |
| SVENSMARK, O | 1 |
| GOLDSTEIN, N | 1 |
| LEIDER, M | 1 |
| BAER, RL | 1 |
| CRAWFORD, SE | 1 |
| JONES, CK | 1 |
| ROBINOW, M | 1 |
| BRAVERMAN, IM | 1 |
| LEVIN, J | 1 |
| BERLINGHOFF, W | 1 |
| SOENNICHSEN, N | 1 |
| WATANABE, S | 1 |
| HOLLAND, P | 2 |
| MAUER, AM | 2 |
| ROBINSON, DS | 1 |
| MACDONALD, MG | 1 |
| HOBIN, FP | 1 |
| Singh, G | 1 |
| Kaushal, S | 1 |
| Gupta, M | 1 |
| Chander Chopra, S | 1 |
| Mostella, J | 1 |
| Pieroni, R | 1 |
| Jones, R | 1 |
| Finch, CK | 1 |
| Sung, SF | 1 |
| Chiang, PC | 1 |
| Tung, HH | 1 |
| Ong, CT | 1 |
| Papp, Z | 1 |
| Török, L | 1 |
| Zaidi, AN | 1 |
| Bedimo, RJ | 1 |
| Geisler, WM | 1 |
| Sierra, NM | 1 |
| García, B | 1 |
| Marco, J | 1 |
| Plaza, S | 1 |
| Hidalgo, F | 1 |
| Bermejo, T | 1 |
| Subbannan, K | 1 |
| Gujral, JS | 1 |
| Amato, A | 1 |
| Marlowe, KF | 1 |
| Beeler, A | 1 |
| Engler, O | 1 |
| Gerber, BO | 1 |
| Pichler, WJ | 2 |
| Kim, CW | 1 |
| Choi, GS | 1 |
| Yun, CH | 1 |
| Kim, DI | 1 |
| Campoamor Serrano, MT | 1 |
| Gómez Díaz-Castroverde, P | 1 |
| Rodríguez Díaz, B | 1 |
| García-Alcalde Fernández, ML | 1 |
| Seitz, CS | 1 |
| Pfeuffer, P | 1 |
| Raith, P | 1 |
| Bröcker, EB | 1 |
| Trautmann, A | 1 |
| Tsuge, I | 2 |
| Okumura, A | 3 |
| Kondo, Y | 1 |
| Itomi, S | 2 |
| Kakami, M | 1 |
| Kawamura, M | 1 |
| Nakajima, Y | 1 |
| Komatsubara, R | 1 |
| Urisu, A | 1 |
| Man, CB | 1 |
| Kwan, P | 1 |
| Baum, L | 1 |
| Yu, E | 1 |
| Lau, KM | 1 |
| Cheng, AS | 1 |
| Ng, MH | 1 |
| Kamachi, Y | 1 |
| Negoro, T | 2 |
| Watanabe, K | 2 |
| Lemme, KA | 1 |
| Seupaul, RA | 1 |
| Ikuta, T | 1 |
| Suzuki, Y | 1 |
| Kato, T | 1 |
| Maecker, B | 1 |
| Meissner, B | 1 |
| Bettoni da Cunha-Riehm, C | 1 |
| Sauer, M | 1 |
| Welte, K | 1 |
| Sykora, KW | 1 |
| Sánchez-Morillas, L | 1 |
| Laguna-Martínez, JJ | 1 |
| Reaño-Martos, M | 1 |
| Rojo-Andrés, E | 1 |
| Gómez-Tembleque, P | 1 |
| Pellón-González, C | 1 |
| Cvetko, B | 1 |
| Ferlic, RM | 1 |
| Sellers, RD | 1 |
| Lillehei, CW | 1 |
| Eliot, RS | 1 |
| DeSwarte, RD | 2 |
| Dostert, P | 1 |
| Benedetti, MS | 1 |
| Ting, S | 1 |
| Dunsky, EH | 1 |
| Lillie, MA | 1 |
| Yang, LC | 1 |
| Honig, PJ | 1 |
| August, CS | 1 |
| Fonseca, JC | 1 |
| Azulay, DR | 1 |
| Rozembau, I | 1 |
| Azulay, RD | 1 |
| Knutsen, AP | 1 |
| Anderson, J | 1 |
| Satayaviboon, S | 1 |
| Slavin, RG | 1 |
| Furst, DE | 1 |
| Gleichmann, H | 2 |
| Kahn, HD | 1 |
| Faguet, GB | 1 |
| Agee, JF | 1 |
| Middleton, HM | 1 |
| Munn, NJ | 1 |
| Baughman, RP | 1 |
| Ploysongsang, Y | 1 |
| Wirman, JA | 1 |
| Bullock, WE | 1 |
| Harney, J | 1 |
| Glasberg, MR | 1 |
| De-Lima, TC | 1 |
| Palermo-Neto, J | 1 |
| Spielberg, SP | 4 |
| Gordon, GB | 1 |
| Blake, DA | 1 |
| Goldstein, DA | 1 |
| Herlong, HF | 1 |
| Stalnikowicz, R | 1 |
| Mosseri, M | 1 |
| Shalev, O | 1 |
| Cook, IF | 1 |
| Shilkin, KB | 1 |
| Reed, WD | 1 |
| Gleichmann, HI | 1 |
| Kutt, H | 1 |
| Solomon, GE | 1 |
| Maddrey, WC | 1 |
| Fruchter, L | 1 |
| Laptook, A | 1 |
| Carpenter, J | 1 |
| Sander, G | 1 |
| Newby, N | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency[NCT01379469] | Phase 2 | 20 participants (Actual) | Interventional | 2012-01-31 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
29 reviews available for phenytoin and Allergy, Drug
| Article | Year |
|---|---|
Cutaneous Hypersensitivity Reaction After Phenytoin Therapy in a Neonate: A Case Report and Review of Literature Elucidating the Potential Pharmacological Plausibility and Preventive Strategies.
Topics: Anticonvulsants; Child; Drug Hypersensitivity; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; | 2023 |
HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Child; Child, Preschool; | 2019 |
Requirement for cardiac telemetry during intravenous phenytoin infusion: guideline fact or guideline fiction?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Ca | 2013 |
Phenytoin in cutaneous medicine: its uses, mechanisms and side effects.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Dermatologic Agents; Drug Hypersensitivity; Drug Inter | 2003 |
Impact of phenytoin therapy on the skin and skin disease.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Child; Connective Tissue Diseases; Drug Eruptio | 2004 |
[Biochemical mechanisms of the hepatotoxicity of psychotropic drugs].
Topics: Acute Disease; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic | 1984 |
Phenytoin: relevant side effects.
Topics: Animals; Blood Coagulation; Bone and Bones; Calcium; Connective Tissue Diseases; Drug Hypersensitivi | 1980 |
Drug-related acute and chronic hepatitis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Hypersen | 1980 |
[Adverse cutaneous reactions to drugs in neurology].
Topics: Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Gingival Hyperplasia; Humans; Hypertrichosis | 1997 |
Anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Drug Interactions; Felbamate; Humans; Phenoba | 1997 |
Bronchiolitis obliterans with organizing pneumonia and cold agglutinin disease associated with phenytoin hypersensitivity syndrome.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Anticonvulsants; Biopsy; Cryptogenic Organizing Pneumonia; Dia | 1997 |
Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Cytochrome P-450 Enzyme System; Drug Hypersensiti | 1998 |
Antiepileptic drug hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; D | 1998 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Adult; Anticonvulsants; Diagnosis, Differential; Drug Hypersensitivity; Humans; Male; Phenytoin; Syn | 1999 |
[Pharmacogenetic research in clinical psychiatry].
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Chlorpromazine; Cholinesteras | 1976 |
Drug-induced mycosis fungoides-like lesions.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Drug Eruptions; Drug Hypersensiti | 1990 |
Cutaneous and immunologic reactions to phenytoin.
Topics: Carcinogens; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Phenytoin; Pregnancy; Teratogens | 1988 |
Hepatic considerations in the use of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Liv | 1987 |
Phenytoin syndrome developing after administration of dilantin for an enflurane-induced seizure.
Topics: Adult; Anesthesia, Dental; Anesthesia, General; Drug Hypersensitivity; Enflurane; Female; Humans; Ph | 1988 |
Phenytoin hypersensitivity syndrome.
Topics: Aged; Child; Drug Hypersensitivity; Humans; Male; Phenytoin; Prognosis; Syndrome | 1987 |
Drug allergy: an overview.
Topics: Anaphylaxis; Anemia; Boston; Desensitization, Immunologic; Drug Hypersensitivity; Fever; Humans; Liv | 1986 |
Drug-induced fever.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Body Temperature Regulation; Drug Hypersensitivity; Fe | 1986 |
Advances in pharmacogenetics.
Topics: Alcohol Oxidoreductases; Catalase; Cholinesterases; Dicumarol; Diseases in Twins; Drug Hypersensitiv | 1973 |
Lymphadenopathy simulating the malignant lymphomas.
Topics: Animals; Biopsy; Dermatitis; Drug Hypersensitivity; Herpes Zoster; Humans; Hyalin; Hyperplasia; Infe | 1974 |
Recent progress in pharmacogenetics.
Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; C | 1969 |
[Lymphocyte culture and its relation to clinical problems].
Topics: Antibody Formation; Culture Techniques; Drug Hypersensitivity; gamma-Globulins; Humans; Immunity, Ce | 1969 |
[New data evidencing the role of antigenic stimulation in the pathogenesis of neoplasms of the lymphatic and plasmocytic systems. I. Can drug-induced hypersensitivity reactions lead to neoplastic proliferation in the lymphatic system?].
Topics: Adjuvants, Immunologic; Antigens, Neoplasm; Antistreptolysin; Diagnosis, Differential; Drug Hypersen | 1972 |
Idiosyncratic hematologic reactions to drugs.
Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Aspir | 1974 |
[On the clinical features, histology and etiology of gingival hyperplasia and the hydantoins].
Topics: Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Gingival Hyperplasia; Humans; Hydantoins; | 1969 |
1 trial available for phenytoin and Allergy, Drug
| Article | Year |
|---|---|
Side effects and mortality associated with use of phenytoin for early posttraumatic seizure prophylaxis.
Topics: Anticonvulsants; Brain Injuries; Double-Blind Method; Drug Hypersensitivity; Humans; Incidence; Phen | 1999 |
176 other studies available for phenytoin and Allergy, Drug
| Article | Year |
|---|---|
Phenobarbital-induced severe cutaneous adverse drug reactions are associated with CYP2C19*2 in Thai children.
Topics: Adolescent; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Child; Child, Preschool; | 2013 |
Anticonvulsant hypersensitivity syndrome (AHS): a case report.
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Exanthema; Fe | 2013 |
Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensiti
Topics: Administration, Oral; Amoxicillin; Animals; Biomarkers; Carbamazepine; Drug Hypersensitivity; Flow C | 2013 |
Phenytoin induced toxic epidermal necrolysis.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Humans; Male; Middle Aged; Phenytoin; Seizure | 2014 |
Life-Threatening and Rare Adverse Effects of Phenytoin.
Topics: Anaphylaxis; Anticonvulsants; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions | 2015 |
Agranulocytosis following phenytoin-induced hypersensitivity syndrome.
Topics: Agranulocytosis; Anti-Bacterial Agents; Anticonvulsants; Cefepime; Cephalosporins; Chemical and Drug | 2009 |
Phenytoin-induced DRESS.
Topics: Adolescent; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Female; Humans; Lymphocyte Count; P | 2009 |
Phenytoin-associated hypersensitivity syndrome with features of DRESS and TEN/SJS.
Topics: Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Female; Humans; Middle Aged; P | 2010 |
Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; Carbamazepine; Disease Susceptibility; | 2011 |
Procalcitonin, a high acute phase reactant in antiepileptic hypersentivity syndrome in pediatric age.
Topics: Adolescent; Anticonvulsants; Calcitonin; Calcitonin Gene-Related Peptide; Carbamazepine; Drug Erupti | 2012 |
Toxic epidermal necrolysis arising as a sequela of drug-induced hypersensitivity syndrome.
Topics: Anticonvulsants; Drug Hypersensitivity; Eosinophilia; Fatal Outcome; Humans; Male; Middle Aged; Mult | 2012 |
Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
Topics: Biomarkers, Pharmacological; Carbamazepine; Drug Hypersensitivity; Genome-Wide Association Study; HL | 2012 |
Severe drug-induced hypersensitivity syndrome with a shared HLA-B allele.
Topics: Adult; Alleles; Anticonvulsants; Drug Hypersensitivity; Female; HLA-B Antigens; Humans; Male; Phenyt | 2012 |
Human herpesvirus 6 encephalitis associated with hypersensitivity syndrome.
Topics: Anticonvulsants; Antiporters; DNA, Viral; Drug Hypersensitivity; Encephalitis, Viral; Exanthema Subi | 2002 |
A case of hypersensitivity syndrome due to phenytoin.
Topics: Adult; Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Meth | 2002 |
A case of phenytoin hypersensitivity syndrome.
Topics: Adolescent; Anticonvulsants; Drug Hypersensitivity; Exanthema; Female; Humans; Lymphatic Diseases; P | 2002 |
A case of phenytoin hypersensitivity.
Topics: Drug Hypersensitivity; Exanthema; Humans; Phenytoin | 1963 |
Drug eruptions from anticonvulsant drugs. Observations on drug-induced lesions that were fixed and lupus-erythematosus-like, and on cross-reactivity between several drugs involved.
Topics: Anticonvulsants; Barbiturates; Drug Eruptions; Drug Hypersensitivity; Humans; Phenytoin; Primidone | 1963 |
Fatal liver necrosis and diphenylhydantoin sensitivity.
Topics: Drug Hypersensitivity; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Liver Diseases; Phenytoin; Seizures | 1962 |
DIPHENYLHYDANTOIN HYPERSENSITIVITY; TREATMENT WITH 6-MERCAPTOPURINE.
Topics: Child; Drug Hypersensitivity; Hypersensitivity; Mercaptopurine; Phenytoin; Prednisolone; Seizures; T | 1963 |
DILANTIN-INDUCED SERUM SICKNESS. CASE REPORT AND INQUIRY INTO ITS MECHANISM.
Topics: Drug Hypersensitivity; Humans; Phenytoin; Serum Sickness; Toxicology | 1963 |
[DEMONSTRATION OF THE "TRANSFER FACTOR" IN HYDANTOIN ALLERGY PRESENTING AS SUBACUTE LUPUS ERYTHEMATOSUS IN GENUINE EPILEPSY].
Topics: Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Epilepsy; Lupus Erythematosus, Systemic; Phe | 1964 |
[HYPERSENSITIVITY ANGIITIS FROM DIPHENYLHYDANTOIN].
Topics: Alopecia; Dexamethasone; Drug Hypersensitivity; Ecchymosis; Humans; Pathology; Phenytoin; Toxicology | 1964 |
DRUG-INDUCED IN-VITRO STIMULATION OF PERIPHERAL LYMPHOCYTES.
Topics: Antigen-Antibody Reactions; Child; Dermatitis; Drug Hypersensitivity; Epilepsy; Fever; Hepatomegaly; | 1964 |
DIPHENYLHYDANOIN-INDUCED HYPERSENSITIVITY REACTION.
Topics: Blood Cell Count; Child; Drug Eruptions; Drug Hypersensitivity; Drug Therapy; Epilepsy; Epilepsy, Te | 1965 |
SODIUM DIPHENYLHYDANTOIN REACTION WITH EVIDENCE OF CIRCULATING ANTIBODIES.
Topics: Antibodies; Anticonvulsants; Drug Hypersensitivity; Drug Therapy; Epilepsy; Epilepsy, Tonic-Clonic; | 1965 |
Cutaneous reactions in patients with solitary cysticercus granuloma on phenytoin sodium.
Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Exanthema; Female; Granuloma, Foreign-Body; Humans; M | 2004 |
Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin.
Topics: Adult; Anticonvulsants; Cross Reactions; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Imm | 2004 |
Charcoal hemoperfusion in an elderly man with life-threatening adverse reactions due to poor metabolism of phenytoin.
Topics: Aged; Anticonvulsants; Charcoal; Drug Hypersensitivity; Drug Overdose; Hemoperfusion; Humans; Male; | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug | 2004 |
Anticonvulsant hypersensitivity syndrome leading to reversible myocarditis.
Topics: Aged; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Heart Failure; Humans; Myocardi | 2005 |
Phenytoin hypersensitivity syndrome masquerading as fever and systemic illness of unknown origin in an HIV-infected patient.
Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Female; Fever of Unknown Origin; HIV Infections; Huma | 2005 |
Cross Hypersensitivity Syndrome between Phenytoin and Carbamazepine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; | 2005 |
Necrotizing lymphadenitis associated with the phenytoin-induced hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Female; Humans; Lymph Nodes; Lymphadenitis; Necrosis; | 2005 |
Severe case of phenytoin-induced anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Drug Hypersensitivity; Female; Humans; Middle Aged; Phenytoin; Seizures | 2005 |
Long-lasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions.
Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Enzyme-Linked I | 2006 |
Drug hypersensitivity to previously tolerated phenytoin by carbamazepine-induced DRESS syndrome.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Humans; Male; Phenytoi | 2006 |
[Hypersensitivity syndrome to phenitoin].
Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Humans; Male; Phenytoin | 2006 |
Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Anticonvulsants; Antidepressive A | 2006 |
Allergen-specific T-cell response in patients with phenytoin hypersensitivity; simultaneous analysis of proliferation and cytokine production by carboxyfluorescein succinimidyl ester (CFSE) dilution assay.
Topics: Adolescent; Allergens; Anticonvulsants; Case-Control Studies; CD4 Antigens; Cell Proliferation; Cell | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Transient hypogammaglobulinemia after antiepileptic drug hypersensitivity.
Topics: Agammaglobulinemia; Anticonvulsants; Child, Preschool; Drug Hypersensitivity; Humans; Male; Phenobar | 2007 |
Anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Female; Humans; Phenytoin; Pruritus | 2007 |
[Drug-induced hypersensitivity due to phenytoin].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Hypersensitivity; Epilepsy; Humans; Male; | 2007 |
Severe graft failure presumably due to phenytoin-induced hypersensitivity syndrome in two patients after bone marrow transplantation.
Topics: Anemia, Sickle Cell; Anticonvulsants; Bone Marrow Transplantation; Child; Drug Hypersensitivity; Fem | 2008 |
A case of hypersensitivity syndrome due to phenytoin.
Topics: Adult; Anticonvulsants; Cross Reactions; Drug Hypersensitivity; Humans; Male; Phenytoin | 2008 |
[Intolerance syndrome in diphenylhydantoin therapy].
Topics: Cerebellum; Drug Hypersensitivity; Electroencephalography; Humans; Male; Phenytoin; Psychoses, Subst | 1966 |
Cardioversion as an adjunct to cardiac surgery.
Topics: Adult; Anticoagulants; Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Chronic Dis | 1967 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons | 1984 |
Diphenylhydantoin-induced hepatitis.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Dermatitis, Exfoliative; Drug Hypersensitivity; | 1982 |
Erythroderma, hypogammaglobulinemia, and T-cell lymphocytosis. Occurrence following therapy with phenytoin.
Topics: Adolescent; Dermatitis, Exfoliative; Drug Hypersensitivity; Humans; Immunoglobulins; Lymphocyte Acti | 1983 |
[Hypersensitivity syndrome caused by phenytoins and phenobarbital].
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; | 1984 |
Immunologic aspects of phenobarbital hypersensitivity.
Topics: Adolescent; Child; Child, Preschool; Drug Hypersensitivity; Humans; Infant; Lymphocyte Activation; P | 1984 |
Use of ibuprofen in unusual circumstances.
Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersens | 1984 |
Studies on the mechanism of drug sensitization: T-cell-dependent popliteal lymph node reaction to diphenylhydantoin.
Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Drug Hypersensitivity; Lymph Nodes; Lympho | 1981 |
Drug-induced liver injury. In vitro demonstration of hypersensitivity to both phenytoin and phenobarbital.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Cross Reactions; Drug Hypersensitivity; Female; | 1984 |
Bronchoalveolar lavage in acute drug-hypersensitivity pneumonitis probably caused by phenytoin.
Topics: Acute Disease; Alveolitis, Extrinsic Allergic; Biopsy; Bronchi; Bronchoscopy; Drug Hypersensitivity; | 1984 |
Myopathy and hypersensitivity to phenytoin.
Topics: Adult; Drug Hypersensitivity; Humans; Male; Myositis; Phenytoin; Status Epilepticus | 1983 |
Central nervous system supersensitivity and withdrawal from long-term diphenylhydantoin treatment.
Topics: Animals; Convulsants; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Male; Phenyto | 1983 |
Predisposition to phenytoin hepatotoxicity assessed in vitro.
Topics: Adult; Chemical and Drug Induced Liver Injury; Disease Susceptibility; Drug Hypersensitivity; Epoxid | 1981 |
Phenytoin-induced arthritis.
Topics: Aged; Arthritis; Drug Hypersensitivity; Female; Humans; Phenytoin | 1982 |
Phenytoin induced granulomatous hepatitis.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Granuloma; Humans | 1981 |
T lymphocytes mediate lymphadenopathy and autoimmunization in graft-versus host reactions and hypersensitivity to diphenylhydantoin.
Topics: Autoimmune Diseases; Drug Hypersensitivity; Graft vs Host Reaction; Immunoblastic Lymphadenopathy; M | 1982 |
Diphenylhydantoin hypersensitivity reaction associated with interstitial pulmonary infiltrates and hypereosinophilia.
Topics: Child; Drug Hypersensitivity; Eosinophilia; Humans; Lung Diseases; Male; Phenytoin | 1981 |
Phenytoin hypersensitivity presenting as postoperative fever.
Topics: Adult; Brain; Craniotomy; Diagnosis, Differential; Drug Hypersensitivity; Female; Fever; Humans; Inf | 1980 |
Phenytoin hypersensitivity.
Topics: Candida; Child; Concanavalin A; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Hum | 1980 |
Dyphenylhydantoin induced hypersensitivity reaction with an unusual purpuric skin lesion.
Topics: Child; Conjunctivitis; Disseminated Intravascular Coagulation; Drug Hypersensitivity; Fever; Humans; | 1980 |
[Case of "exanthematous pseudolymphoma" due to diphenylhydantoin hypersensitivity with a transitory immunologic deficit].
Topics: Adolescent; Drug Hypersensitivity; Exanthema; Humans; Immunologic Deficiency Syndromes; Lymphoma; Ma | 1980 |
Anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Fever; Humans; Lymphatic Disea | 1995 |
Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine.
Topics: Anticonvulsants; Carbamazepine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; C | 1995 |
The anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Bronchial Diseases; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Fa | 1993 |
[Phenytoin hypersensitivity syndrome].
Topics: Adolescent; Drug Hypersensitivity; Humans; Male; Phenytoin; Syndrome | 1994 |
The role of gallium-67-citrate in the detection of phenytoin-induced pneumonitis.
Topics: Alveolitis, Extrinsic Allergic; Citrates; Citric Acid; Drug Hypersensitivity; Gallium Radioisotopes; | 1994 |
Anticonvulsant hypersensitivity.
Topics: Carbamazepine; Drug Hypersensitivity; Humans; Male; Middle Aged; Neutropenia; Phenytoin; Skin Diseas | 1994 |
[Hypersensitivity to aromatic anticonvulsive agents. Report of 2 cases].
Topics: Adult; Drug Hypersensitivity; Female; Humans; Phenytoin; Seizures | 1993 |
Human anti-endoplasmic reticulum autoantibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s)
Topics: Adult; Animals; Anticonvulsants; Autoantibodies; Autoantigens; Carbamazepine; Cell Line; Cross React | 1993 |
Diazepam by continuous intravenous infusion for status epilepticus in anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Child, Preschool; Diazepam; Drug Hypersensitivity; Female; Hospitals, Pediatric; Ho | 1993 |
A potentially fatal drug reaction.
Topics: Anticonvulsants; Diagnosis, Differential; Drug Hypersensitivity; Humans; Male; Middle Aged; Phenytoi | 1996 |
Phenytoin hypersensitivity syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Phenyt | 1996 |
Allergic reactions to phenytoin in a general hospital in Singapore.
Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Female; Hospitals, General; Humans; Male; Phenytoin; | 1996 |
Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity; Female; Hospitaliza | 1997 |
Anticonvulsant usage is associated with an increased risk of procarbazine hypersensitivity reactions in patients with brain tumors.
Topics: Adult; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain | 1997 |
Anticonvulsant hypersensitivity: an unfortunate case of triple exposure to phenytoin.
Topics: Aged; Anticonvulsants; Continuity of Patient Care; Drug Hypersensitivity; Emergency Service, Hospita | 1997 |
Anticonvulsant cross-sensitivity.
Topics: Anticonvulsants; Carbamazepine; Cross Reactions; Drug Hypersensitivity; Humans; Phenobarbital; Pheny | 1997 |
Heavy proteinuria, podocyte hypertrophy and severe systemic manifestations in a patient on phenytoin therapy.
Topics: Adult; Drug Hypersensitivity; Humans; Hypertrophy; Kidney; Kidney Glomerulus; Male; Phenytoin; Prote | 1997 |
A 61-year-old woman with thrombocytopenia and a rash.
Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Phenytoin; Purpura, Thrombotic Thrombocytopenic | 1998 |
Allergic hypersensitivity to antiepileptic drugs: past, present, and future.
Topics: Anticonvulsants; Child; Drug Hypersensitivity; Epilepsy; Forecasting; Germany; History, 20th Century | 1998 |
Quantifying the costs of serious adverse drug reactions to antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Direct Service Costs; Drug Costs; Drug Hypersensitivity; Epileps | 1998 |
Phenytoin hypersensitivity syndrome with fatal evolution.
Topics: Anticonvulsants; Drug Hypersensitivity; Fatal Outcome; Female; Humans; Liver Failure; Middle Aged; P | 1999 |
Anticonvulsant hypersensitivity syndrome with an epoxide hydrolase defect.
Topics: Anticonvulsants; Drug Hypersensitivity; Epilepsy; Humans; Male; Middle Aged; Neurocysticercosis; Phe | 1999 |
Anticonvulsant hypersensitivity syndrome occurring as sepsis with multiorgan dysfunction.
Topics: Anticonvulsants; Drug Hypersensitivity; Humans; Male; Middle Aged; Multiple Organ Failure; Phenytoin | 1999 |
Successful treatment with gabapentin in the presence of hypersensitivity syndrome to phenytoin and carbamazepine: a report of three cases.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Hypersens | 1999 |
Fatal phenytoin hypersensitivity syndrome.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Drug Hypersensitivity; Fatal Outcome; Female; Humans; Phen | 1999 |
A very early onset of respiratory failure due to phenytoin-associated hypersensitivity syndrome and concomitant glucocorticoid administration.
Topics: Aged; Anticonvulsants; Dexamethasone; Drug Hypersensitivity; Drug Interactions; Glucocorticoids; Hum | 2000 |
[Phenytoin-induced hypersensitivity reaction with liver failure].
Topics: Anticonvulsants; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Sche | 2000 |
Development of a pulmonary phenytoin-associated hypersensitivity reaction despite concomitant dexamethasone and prednisolone administration.
Topics: Aged; Dexamethasone; Drug Hypersensitivity; Humans; Male; Phenytoin; Prednisolone; Respiratory Insuf | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Surviva | 2000 |
Successful treatment of antiepileptic drug hypersensitivity syndrome with intravenous immune globulin.
Topics: Anticonvulsants; Child; Drug Eruptions; Drug Hypersensitivity; Humans; Immunoglobulins, Intravenous; | 2001 |
Possible atypical cross-sensitivity between phenytoin and carbamazepine in the anticonvulsant hypersensitivity syndrome.
Topics: Aged; Anticonvulsants; Diethylcarbamazine; Drug Hypersensitivity; Female; Humans; Phenytoin; Syndrom | 2001 |
Antiepileptic hypersensitivity syndrome in children.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Anticonvulsants; Child; Diethylcarbamazi | 2001 |
Anticonvulsant hypersensitivity syndrome associated with reactivation of cytomegalovirus.
Topics: Anticonvulsants; Cytomegalovirus; Cytomegalovirus Infections; Drug Eruptions; Drug Hypersensitivity; | 2001 |
Induction of hypersensitivity to a previously tolerated antiepileptic drug by a second antiepileptic drug.
Topics: Adult; Anticonvulsants; Carbamazepine; Cross Reactions; Drug Eruptions; Drug Hypersensitivity; Drug | 2001 |
Phenytoin hypersensitivity syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Drug Hypersensitivity; Eosinophilia; Epidermis; Female; Hepatiti | 2001 |
Cutaneous drug reaction case reports: from the world literature.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Bupropion; Celecoxib; Chlorquinaldol; Cytarabi | 2002 |
[Hypersensitivity reaction to phenytoin].
Topics: Aged; Aged, 80 and over; Anticonvulsants; Drug Hypersensitivity; Female; Humans; Phenytoin | 2001 |
Anticonvulsant hypersensitivity syndrome with marked eosinophilia in treatment of diabetic neuropathy.
Topics: Adult; Anticonvulsants; Carbamazepine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Hypers | 2002 |
Immunoblastic lymphadenopathy, systemic lupus erythematosus, and related disorders. Possible pathogenetic pathways.
Topics: Animals; Autoantibodies; B-Lymphocytes; Drug Hypersensitivity; Graft vs Host Reaction; Humans; Immun | 1979 |
Fatal benign phenytoin hypersensitivity.
Topics: Drug Hypersensitivity; Eosinophilia; Nephritis, Interstitial; Phenytoin; Status Epilepticus | 1977 |
[Lymphadenopathy in phenytoin treatment].
Topics: Adult; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Humans; Lymph Nodes; | 1978 |
Drug-induced lung disease.
Topics: Adult; Anticoagulants; Antihypertensive Agents; Antineoplastic Agents; Arthritis; Cromolyn Sodium; D | 1978 |
Diphenylhydantoin sensitivity. a syndrome resembling infectious mononucleosis with a morbilliform rash and cholestatic hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Child; Cholestasis; Diagnosis, Differential; Drug Eruptions; | 1975 |
[Phenytoin-induced acne].
Topics: Acne Vulgaris; Adult; Cysts; Drug Eruptions; Drug Hypersensitivity; Epilepsy; Female; Humans; Phenyt | 1977 |
Fatal benign phenytoin lymphadenopathy.
Topics: Aged; Drug Hypersensitivity; Eosinophilia; Humans; Kidney; Lymphatic Diseases; Male; Phenytoin; Skin | 1979 |
Phenytoin hypersensitivity: 38 cases.
Topics: Adolescent; Adult; Aged; Anemia; Child; Child, Preschool; Drug Hypersensitivity; Female; Humans; Imm | 1979 |
Phenytoin hypersensitivity.
Topics: Drug Hypersensitivity; Humans; Phenobarbital; Phenytoin; Skin Diseases | 1977 |
Diphenylhydantoin interstitial nephritis. Roles of cellular and humoral immunologic injury.
Topics: Autoantibodies; Basement Membrane; Child; Drug Hypersensitivity; Female; Humans; Immunity, Cellular; | 1978 |
[Stevens-Johnson syndrome as an early allergic reaction to diphenylhydantoin].
Topics: Adult; Drug Hypersensitivity; Epilepsies, Partial; Humans; Male; Phenytoin; Stevens-Johnson Syndrome | 1976 |
[Lymphadenopathy in phenytoin treatment (author's transl)].
Topics: Adolescent; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Female; Hodgkin | 1976 |
Phenytoin-induced pseudolymphoma syndrome: an immunologic study.
Topics: Adult; Antibody Formation; Drug Hypersensitivity; Epilepsy; Female; Humans; Hypersensitivity, Delaye | 1977 |
Diphenylhydantoin-induced acute renal failure.
Topics: Acute Kidney Injury; Drug Hypersensitivity; Humans; Male; Middle Aged; Phenytoin | 1977 |
Interstitial nephritis due to phenytoin hypersensitivity.
Topics: Antibodies; Basement Membrane; Biopsy; Child; Drug Hypersensitivity; Humans; Kidney Tubules; Lymphoc | 1977 |
Reversible renal failure and myositis caused by phenytoin hypersensitivity.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Drug Hypersensitivity; Erythema; Female; Humans | 1976 |
Phenytoin sensitivity in a case of phenytoin-associated Hodgkin's disease.
Topics: Adult; DNA; Drug Hypersensitivity; Hodgkin Disease; Humans; Hypersensitivity, Delayed; Lymphocyte Ac | 1975 |
Letter: Severe hypersensitivity to diphenylhydantoin with circulating antibodies to the drug.
Topics: Adolescent; Antibodies; Drug Hypersensitivity; Humans; Hypersensitivity; Male; Phenytoin; Seizures | 1975 |
Diphenylhydantoin-induced serum sickness with fibrin-platelet thrombi in lymph node microvasculature.
Topics: Acute Disease; Adolescent; Blood Coagulation Disorders; Drug Hypersensitivity; Humans; Lymph Nodes; | 1975 |
Severe phenytoin hypersensitivity with myopathy: a case report.
Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Muscular Diseases; Phenytoin | 1992 |
Familial occurrence of hypersensitivity to phenytoin.
Topics: Adult; Animals; Carbamazepine; Drug Hypersensitivity; Female; Humans; In Vitro Techniques; Mice; Phe | 1991 |
Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cell Death; Drug Hypersensitivity; Female; | 1991 |
Phenytoin hypersensitivity syndrome: a case report.
Topics: Adult; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypersensitivity; Heart | 1991 |
In-vitro assessment of a hypersensitivity syndrome associated with sorbinil.
Topics: Adult; Animals; Biotransformation; Diabetes Mellitus; Drug Hypersensitivity; Female; Humans; Imidazo | 1991 |
Phenytoin hypersensitivity.
Topics: Acute Kidney Injury; Adult; Drug Eruptions; Drug Hypersensitivity; Endocarditis; Humans; Male; Myosi | 1990 |
Phenytoin-carbamazepine cross-sensitivity.
Topics: Adult; Blood Cell Count; Carbamazepine; Cross Reactions; Drug Hypersensitivity; Female; Humans; Live | 1989 |
Phenytoin hepatotoxicity masked by corticosteroids.
Topics: Brain Edema; Chemical and Drug Induced Liver Injury; Dexamethasone; Drug Hypersensitivity; Humans; L | 1989 |
Phenytoin-induced acute respiratory failure with pulmonary eosinophilia.
Topics: Aged; Drug Hypersensitivity; Female; Humans; Phenytoin; Pulmonary Eosinophilia; Respiratory Insuffic | 1989 |
Idiosyncratic reactions to phenytoin.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Eruptions; | 1987 |
Zinc status and delayed cutaneous hypersensitivity in handicapped children treated with anticonvulsants.
Topics: Adolescent; Child; Child, Preschool; Dinitrochlorobenzene; Disabled Persons; Drug Hypersensitivity; | 1987 |
Permanent intrinsic B cell immunodeficiency caused by phenytoin hypersensitivity.
Topics: Adult; Agammaglobulinemia; Antibodies, Monoclonal; B-Lymphocytes; Drug Hypersensitivity; Epilepsy, P | 1986 |
Diphenylhydantoin-induced hypersensitivity reaction with interstitial nephritis.
Topics: Autoantigens; Child; Drug Eruptions; Drug Hypersensitivity; Female; Histiocytes; Humans; Immunity, C | 1985 |
Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; D | 1988 |
[Hypersensitivity myocarditis probably due to phenytoin].
Topics: Drug Hypersensitivity; Female; Humans; Meningeal Neoplasms; Meningioma; Middle Aged; Myocarditis; Ph | 1988 |
Drug fever.
Topics: Allopurinol; Anti-Bacterial Agents; Body Temperature Regulation; Drug Hypersensitivity; Fever; Human | 1986 |
Phenytoin, leukopenia, and remission of eczema.
Topics: Drug Hypersensitivity; Eczema; Female; Humans; Leukopenia; Middle Aged; Phenytoin; Remission, Sponta | 1987 |
Immunological studies on delayed hypersensitivity to phenytoin--II. The delayed skin reaction induced by BSA-phenytoin conjugate.
Topics: Animals; Cell Migration Inhibition; Drug Hypersensitivity; Gingiva; Guinea Pigs; Hypersensitivity, D | 1987 |
Phenytoin-induced hypersensitivity reactions.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Lymphatic Dise | 1987 |
Phenytoin hypersensitivity with pulmonary involvement in a hemophiliac patient with human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Hypersensitivity; Female; Hemophilia A; Humans; Phen | 1987 |
[Severe diphenylhydantoin hypersensitivity: analysis of 11 cases].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Drug Hypersensitivity; Female; Humans; Liver; Lym | 1987 |
Phenytoin hypersensitivity: a case of severe acute rhabdomyolysis.
Topics: Acute Disease; Adult; Drug Hypersensitivity; Humans; Male; Phenytoin; Rhabdomyolysis | 1986 |
[Bone marrow-damaging effect of various drugs].
Topics: Antitubercular Agents; Bone Marrow; Chloramphenicol; Drug Hypersensitivity; Drug Therapy, Combinatio | 1985 |
Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Report of a patient treated with corticosteroid "pulse therapy".
Topics: Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Male; Methylprednisolone; Mid | 1985 |
Diphenylhydantoin-induced hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Liver; Middle Aged; P | 1985 |
Seasonal incidence of phenytoin allergy unrelated to plasma levels.
Topics: Adolescent; Adult; Aged; Child; Drug Hypersensitivity; Erythema; Female; Humans; Male; Middle Aged; | 1985 |
Myocarditis related to drug hypersensitivity.
Topics: Adrenal Cortex Hormones; Adult; Drug Hypersensitivity; Electrocardiography; Eosinophilia; Female; He | 1985 |
Drugs and genes.
Topics: Acetyltransferases; Drug Antagonism; Drug Hypersensitivity; Drug Interactions; Drug-Related Side Eff | 1973 |
Letter: Tests for drug allergy.
Topics: Adult; Carbamazepine; Drug Hypersensitivity; Epilepsy, Temporal Lobe; Humans; Lymphocyte Activation; | 1974 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec | 1974 |
[Pharmacogenetics: variability of drug effects and metabolic reactions].
Topics: Acetyltransferases; Anemia, Hemolytic, Congenital; Anesthesia; Animals; Biopharmaceutics; Cholineste | 1974 |
Diphenylhydantoin--induced hepatic necrosis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Female | 1974 |
[Phenytoin (5,5-diphenylhydantoin) hypersensitivity presenting a clinical picture of scarlatiniform erythroderma].
Topics: Child; Dermatitis, Exfoliative; Drug Hypersensitivity; Epilepsy; Female; Hematopoietic System; Human | 1966 |
[Outpatient therapy of epilepsy].
Topics: Anticonvulsants; Barbiturates; Depression, Chemical; Drug Eruptions; Drug Hypersensitivity; Epilepsi | 1970 |
An unusual dual hypersensitivity reaction induced by diphenylhydantoin.
Topics: Dermatitis, Exfoliative; Drug Hypersensitivity; Female; Humans; Leukocyte Count; Lymphoma; Middle Ag | 1973 |
Leukopenia as an unusual component of diphenylhydantoin hypersensitivity. A case with pruritus, rash, fever, lymphadenopathy, but low leukocyte count.
Topics: Child; Drug Eruptions; Drug Hypersensitivity; Fever; Humans; Leukocyte Count; Leukopenia; Lymphatic | 1973 |
Diphenylhydantoin (Dilantin) hypersensitivity.
Topics: Blood Cell Count; Blood Chemical Analysis; Child; Diagnosis, Differential; Drug Hypersensitivity; Fe | 1970 |
[Hydantoins and neurologic complications].
Topics: Adolescent; Brain Diseases; Cerebrospinal Fluid Proteins; Drug Hypersensitivity; Epilepsy; Humans; H | 1973 |
[What is certain in the therapy of heart diseases?].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Output; Digitalis | 1969 |
[Lymphocyte transformation test in drug hypersensitivity].
Topics: Ampicillin; Drug Hypersensitivity; Exanthema; Humans; Immunologic Techniques; Lymphocyte Activation; | 1972 |
[Complications of medical therapy for epilepsy in children and adolescents].
Topics: Anticonvulsants; Child; Diplopia; Drug Hypersensitivity; Drug Therapy, Combination; Epilepsy; Headac | 1973 |
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocyt | 1974 |
Lymphocytic thyroiditis possibly induced by diphenylhydantoin.
Topics: Adult; Antibodies; Complement Fixation Tests; Drug Hypersensitivity; Female; Fluorescent Antibody Te | 1969 |
[Results of parenteral diphenylhydantoin therapy of status epilepticus from the years 1959-1965].
Topics: Adolescent; Adult; Aged; Autopsy; Brain; Child; Child, Preschool; Drug Hypersensitivity; Epilepsy, T | 1969 |
[Speech disorders in children with cerebral convulsions].
Topics: Adolescent; Barbiturates; Carbamazepine; Drug Hypersensitivity; Electroencephalography; Epilepsy; Et | 1972 |
Adverse effects of hydantoins.
Topics: Ataxia; Drug Hypersensitivity; Folic Acid; Humans; Neurologic Manifestations; Phenytoin; Skin Manife | 1971 |
[Hydantoin-hyperplasia].
Topics: Dentistry; Drug Hypersensitivity; Gingival Hyperplasia; Phenytoin | 1967 |
Digitalis toxicity. How to deal with it.
Topics: Arrhythmias, Cardiac; Digitalis Glycosides; Drug Hypersensitivity; Heart Diseases; Phenytoin; Procai | 1970 |
Pseudolymphoma syndrome. A sensitivity to anticonvulsant drugs.
Topics: Biopsy; Blood Cell Count; Blood Chemical Analysis; Chlordiazepoxide; Drug Hypersensitivity; Female; | 1968 |
Drugs and heredity. Pharmacogenetics--the study of heritable variations in drug response.
Topics: Drug Hypersensitivity; Genetics, Medical; Humans; Isoniazid; Metabolic Diseases; Metabolism, Inborn | 1969 |
Significance of seizures in patients receiving psychotropic drugs.
Topics: Adult; Drug Hypersensitivity; Epilepsy; Humans; Male; Meprobamate; Phenytoin; Schizophrenia; Seizure | 1965 |