phenytoin has been researched along with Alexander Disease in 1 studies
Alexander Disease: Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain. Rosenthal fibers are GLIAL FIBRILLARY ACIDIC PROTEIN aggregates found in ASTROCYTES. Juvenile- and adult-onset types show progressive atrophy of the lower brainstem instead. De novo mutations in the GFAP gene are associated with the disease with propensity for paternal inheritance.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ruzza, P | 1 |
| Vitale, RM | 1 |
| Hussain, R | 1 |
| Biondi, B | 1 |
| Amodeo, P | 1 |
| Sechi, G | 1 |
| Siligardi, G | 1 |
1 other study available for phenytoin and Alexander Disease
| Article | Year |
|---|---|
Interactions of GFAP with ceftriaxone and phenytoin: SRCD and molecular docking and dynamic simulation.
Topics: Alexander Disease; alpha-Synuclein; Animals; Astrocytes; Binding Sites; Ceftriaxone; Glial Fibrillar | 2016 |