phenytoin has been researched along with Agranulocytosis in 29 studies
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenytoin, one of the most common antiepileptic drugs, is a major cause of antiepileptic drug hypersensitivity syndrome (AHS), which is a rare but potentially fatal complication." | 7.75 | Agranulocytosis following phenytoin-induced hypersensitivity syndrome. ( Imai, K; Ito, S; Oguni, H; Osawa, M; Sasaki, K; Shioda, M, 2009) |
| "Agranulocytosis is a rare side effect of phenytoin treatment." | 7.68 | Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction? ( McClune, GL; Sharafuddin, MJ; Spanheimer, RG, 1991) |
| "A case of phenytoin-induced agranulocytosis is presented." | 7.66 | Phenytoin-induced agranulocytosis after treatment for a gunshot wound to the face. ( Goldberg, JS; Lazarus, HM; Spetzler, RF; Strickland, RD, 1983) |
| "We have presented two cases of agranulocytosis occurring in patients receiving a combination antiarrhythmic regimen." | 5.26 | Agranulocytosis during combined procainamide and phenytoin therapy. ( Crook, JE; Leftwich, RB; Natelson, EA; Woosley, RL, 1979) |
| "Phenytoin, one of the most common antiepileptic drugs, is a major cause of antiepileptic drug hypersensitivity syndrome (AHS), which is a rare but potentially fatal complication." | 3.75 | Agranulocytosis following phenytoin-induced hypersensitivity syndrome. ( Imai, K; Ito, S; Oguni, H; Osawa, M; Sasaki, K; Shioda, M, 2009) |
| "Agranulocytosis is a rare side effect of phenytoin treatment." | 3.68 | Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction? ( McClune, GL; Sharafuddin, MJ; Spanheimer, RG, 1991) |
| "A case of phenytoin-induced agranulocytosis is presented." | 3.66 | Phenytoin-induced agranulocytosis after treatment for a gunshot wound to the face. ( Goldberg, JS; Lazarus, HM; Spetzler, RF; Strickland, RD, 1983) |
| "Two patients with agranulocytosis associated with diphenylhydantoin (DPH) therapy and clinical data suggesting suppression of granulopoiesis were investigated using in vitro culture techniques for committed granulocyte/macrophage precursors." | 1.26 | Drug-induced agranulocytosis: in vitro evidence for immune suppression of granulopoiesis and a cross-reacting lymphocyte antibody. ( Lane, TA; Mendelsohn, J; Taetle, R, 1979) |
| "We have presented two cases of agranulocytosis occurring in patients receiving a combination antiarrhythmic regimen." | 1.26 | Agranulocytosis during combined procainamide and phenytoin therapy. ( Crook, JE; Leftwich, RB; Natelson, EA; Woosley, RL, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (79.31) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, S | 1 |
| Shioda, M | 1 |
| Sasaki, K | 1 |
| Imai, K | 1 |
| Oguni, H | 1 |
| Osawa, M | 1 |
| SCHOEMPERLEN, CB | 1 |
| TURNER, P | 1 |
| SLAVIN, RG | 1 |
| BROUN, GO | 1 |
| BERNHARDT, H | 1 |
| Strickland, RD | 1 |
| Goldberg, JS | 1 |
| Lazarus, HM | 1 |
| Spetzler, RF | 1 |
| Fleet, S | 1 |
| Knipping, W | 1 |
| Sazie, E | 1 |
| Jaffe, JP | 1 |
| Laurenson, IF | 1 |
| Buckoke, C | 1 |
| Davidson, C | 1 |
| Gutteridge, C | 1 |
| Rawanduzy, A | 1 |
| Sarkis, A | 1 |
| Rovit, RL | 1 |
| Kakar, A | 1 |
| Byotra, SP | 1 |
| Al-Kawas, FH | 1 |
| Lenes, BA | 1 |
| Sacher, RA | 1 |
| Taetle, R | 1 |
| Lane, TA | 1 |
| Mendelsohn, J | 1 |
| Crook, JE | 1 |
| Woosley, RL | 1 |
| Leftwich, RB | 1 |
| Natelson, EA | 1 |
| Kjer, JJ | 1 |
| Tsan, MF | 1 |
| Mehlman, DJ | 1 |
| Green, RS | 1 |
| Bell, WR | 1 |
| Sharafuddin, MJ | 1 |
| Spanheimer, RG | 1 |
| McClune, GL | 1 |
| Matsuzaki, M | 1 |
| Tokioka, T | 1 |
| Suga, K | 1 |
| Sueoka, E | 1 |
| Ono, K | 1 |
| Sano, M | 1 |
| Shimamoto, Y | 1 |
| Yamaguchi, M | 1 |
| Gabl, M | 1 |
| Kostron, H | 1 |
| Golochevskaia, VS | 1 |
| Abendroth, K | 1 |
| Müller, W | 1 |
| Pisciotta, AV | 1 |
| Yunis, AA | 1 |
| Bottomley, WK | 1 |
| Eklind, RR | 1 |
| Moffitt, WC | 1 |
| Bercel, NA | 1 |
| Henstell, HH | 1 |
| Okuda, M | 1 |
| Furusawa, S | 1 |
| Sakurai, T | 1 |
| Shishido, H | 1 |
| Baldwin, RL | 1 |
| Peters, JE | 1 |
3 reviews available for phenytoin and Agranulocytosis
| Article | Year |
|---|---|
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
Idiosyncratic hematologic reactions to drugs.
Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Aspir | 1974 |
Drug--induced bone marrow injury.
Topics: Adult; Agranulocytosis; Anemia, Aplastic; Bone Marrow Diseases; Child, Preschool; Chloramphenicol; H | 1969 |
26 other studies available for phenytoin and Agranulocytosis
| Article | Year |
|---|---|
Agranulocytosis following phenytoin-induced hypersensitivity syndrome.
Topics: Agranulocytosis; Anti-Bacterial Agents; Anticonvulsants; Cefepime; Cephalosporins; Chemical and Drug | 2009 |
Agranulocytosis due to dilantin sodium.
Topics: Agranulocytosis; Humans; Phenytoin; Sodium | 1947 |
Granulocytopenia after treatment with phenytoin sodium.
Topics: Agranulocytosis; Humans; Hydantoins; Phenytoin | 1960 |
Agranulocytosis after diphenylhydantoin and chlorothiazide therapy. A case report and discussion of the evidence for the primary role of diphenylhydantoin.
Topics: Agranulocytosis; Chlorothiazide; Hydantoins; Phenytoin | 1961 |
Fatal granulocytopenia following hydantoins, mesantoin and dilantin; report of a case.
Topics: Agranulocytosis; Hydantoins; Mephenytoin; Phenytoin | 1950 |
Phenytoin-induced agranulocytosis after treatment for a gunshot wound to the face.
Topics: Adult; Agranulocytosis; Humans; Male; Mandibular Fractures; Neck Injuries; Phenytoin; Seizures; Woun | 1983 |
Agranulocytosis, procainamide, and phenytoin.
Topics: Aged; Agranulocytosis; Humans; Male; Phenytoin; Procainamide | 1984 |
[Problems of evaluating rare adverse drug reactions using as an example agranulocytosis induced by anti-arrhythmia agents].
Topics: Aged; Agranulocytosis; Ajmaline; Anti-Arrhythmia Agents; Drug Therapy, Combination; Drug-Related Sid | 1980 |
Severe granulocytopenia with cimetidine and phenytoin.
Topics: Adolescent; Agranulocytosis; Cimetidine; Drug Interactions; Guanidines; Humans; Male; Phenytoin | 1980 |
Delayed fatal agranulocytosis in an epileptic taking primidone and phenytoin.
Topics: Adult; Agranulocytosis; Drug Therapy, Combination; Epilepsy; Fatal Outcome; Humans; Male; Phenytoin; | 1994 |
Severe phenytoin-induced bone marrow depression and agranulocytosis treated with human recombinant granulocyte-macrophage colony-stimulating factor. Case report.
Topics: Aged; Agranulocytosis; Bone Marrow; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans | 1993 |
Phenytoin induced severe agranulocytosis and hepatitis.
Topics: Agranulocytosis; Anticonvulsants; Chemical and Drug Induced Liver Injury; Female; Humans; Middle Age | 1999 |
Cimetidine and agranulocytosis.
Topics: Aged; Agranulocytosis; Cimetidine; Drug Synergism; Female; Guanidines; Humans; Phenytoin | 1979 |
Drug-induced agranulocytosis: in vitro evidence for immune suppression of granulopoiesis and a cross-reacting lymphocyte antibody.
Topics: Agranulocytosis; Bone Marrow Cells; Cell Division; Hematopoiesis; Humans; Immunosuppression Therapy; | 1979 |
Agranulocytosis during combined procainamide and phenytoin therapy.
Topics: Acetylation; Acetyltransferases; Aged; Agranulocytosis; Arrhythmias, Cardiac; Drug Therapy, Combinat | 1979 |
[Phenytoin-induced agranulocytosis].
Topics: Adult; Agranulocytosis; Humans; Male; Phenytoin | 1978 |
Letter: Dilantin, agranulocytosis, and phagocytic marrow histiocytes.
Topics: Adolescent; Agranulocytosis; Bone Marrow; Bone Marrow Cells; Female; Histiocytes; Humans; Phagocytos | 1976 |
Phenytoin-induced agranulocytosis: a nonimmunologic idiosyncratic reaction?
Topics: Agranulocytosis; Brain Neoplasms; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; | 1991 |
[Phenytoin induced agranulocytosis: direct and T cell-mediated mechanisms].
Topics: Agranulocytosis; Colony-Forming Units Assay; Humans; Male; Middle Aged; Phenytoin; Seizures; T-Lymph | 1990 |
Diphenylhydantoin induced granulocytopenia following a seizure prophylaxis after a depressed skull fracture.
Topics: Aged; Agranulocytosis; Brain Concussion; Epilepsy, Post-Traumatic; Humans; Male; Parietal Bone; Phen | 1986 |
[Therapeutic conclusions from the immunologic events in agranulocytosis].
Topics: Adult; Aged; Agranulocytosis; Ampicillin; Antifungal Agents; Barbiturates; Blood Transfusion; Bone M | 1972 |
Case report: diphenylhydantoin sodium-induced thrombocytopenia and leukopenia.
Topics: Agranulocytosis; Dentistry; Phenytoin; Thrombocytopenia | 1971 |
The relationship between some anticonvulsants and tumors of the blood forming organs.
Topics: Adult; Agranulocytosis; Anticonvulsants; Female; Genetics, Medical; Humans; Hydantoins; Leukocytes; | 1970 |
[Correlation between systemic lupus erythematosus and anti-convulsants. Case of systemic lupus erythematosus with aggravated lupus and granulocytopenia caused by diphenyl-hydantoin].
Topics: Adult; Agranulocytosis; Female; Humans; Lupus Erythematosus, Systemic; Phenytoin | 1970 |
Carbamazepine (Tegretol).
Topics: Agranulocytosis; Anemia, Aplastic; Blood Platelet Disorders; Carbamazepine; Dibenzazepines; Hematolo | 1968 |
Hematologic complications from tranquilizers in children.
Topics: Adolescent; Age Factors; Agranulocytosis; Bone Marrow Examination; Brain Damage, Chronic; Brain Dise | 1968 |