Page last updated: 2024-10-21

phenytoin and Agammaglobulinemia

phenytoin has been researched along with Agammaglobulinemia in 11 studies

Agammaglobulinemia: An immunologic deficiency state characterized by an extremely low level of generally all classes of gamma-globulin in the blood.

Research Excerpts

ExcerptRelevanceReference
"We report the case of a 24-y-old woman who presented with repeated episodes of otitis due to panhypogammaglobulinemia and low levels of mature CD19 + B cells (84 cells/microl) associated with phenytoin treatment."7.71Reversible panhypogammaglobulinemia associated with phenytoin treatment. ( Pereira, LF; Sanchez, JF, 2002)
"We report the case of a 24-y-old woman who presented with repeated episodes of otitis due to panhypogammaglobulinemia and low levels of mature CD19 + B cells (84 cells/microl) associated with phenytoin treatment."3.71Reversible panhypogammaglobulinemia associated with phenytoin treatment. ( Pereira, LF; Sanchez, JF, 2002)
"Phenytoin-induced panhypogammaglobulinemia mimicking the common variable immunodeficiency syndrome is rare."3.67Reversible common variable immunodeficiency syndrome induced by phenytoin. ( Block, JM; Macris, NT; Schwimmer, D; Travin, M, 1989)
"We report a patient who, 3 weeks after initiation of therapy, experienced a hypersensitivity reaction to phenytoin manifested as rash, lymphadenopathy, elevated serum transaminase levels, and subsequent panhypogammaglobulinemia with IgG, 180 mg/dl (control range 639 to 1349); IgA, 15 mg/dl (control range 70 to 312); and IgM, 0 mg/dl (control range 56 to 352)."3.67Permanent intrinsic B cell immunodeficiency caused by phenytoin hypersensitivity. ( Fawcett, WA; Guerra, IC; Lawrence, EC; Redmon, AH; Rosenblatt, HM; Shearer, WT, 1986)
"Various immunological features were measured in 20 patients with epilepsy who had received prolonged treatment with hydantoins."3.65Immunological abnormalities and hydantoins. ( Grob, PJ; Herold, GE, 1972)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pereira, LF1
Sanchez, JF1
Okumura, A1
Tsuge, I1
Kamachi, Y1
Negoro, T1
Watanabe, K1
Dosch, HM1
Jason, J1
Gelfand, EW1
Kanoh, T1
Uchino, H1
Matzner, Y1
Polliack, A1
Joubert, PH1
Aucamp, AK1
Potgieter, GM1
Verster, F1
Britigan, BE1
Travin, M1
Macris, NT1
Block, JM1
Schwimmer, D1
Guerra, IC1
Fawcett, WA1
Redmon, AH1
Lawrence, EC1
Rosenblatt, HM1
Shearer, WT1
De Gast, GC1
The, TH1
Viersma, JW1
Marrink, J1
Arisz, LA1
Grob, PJ1
Herold, GE1

Other Studies

11 other studies available for phenytoin and Agammaglobulinemia

ArticleYear
Reversible panhypogammaglobulinemia associated with phenytoin treatment.
    Scandinavian journal of infectious diseases, 2002, Volume: 34, Issue:10

    Topics: Adult; Agammaglobulinemia; Anticonvulsants; Epilepsy; Female; Follow-Up Studies; Headache; Humans; I

2002
Transient hypogammaglobulinemia after antiepileptic drug hypersensitivity.
    Pediatric neurology, 2007, Volume: 36, Issue:5

    Topics: Agammaglobulinemia; Anticonvulsants; Child, Preschool; Drug Hypersensitivity; Humans; Male; Phenobar

2007
Transient antibody deficiency and abnormal T suppressor cells induced by phenytoin.
    The New England journal of medicine, 1982, 02-18, Volume: 306, Issue:7

    Topics: Agammaglobulinemia; Child; Humans; Immunoglobulins; Immunologic Deficiency Syndromes; Male; Phenytoi

1982
Letter: Immunodeficiency and epilepsy.
    Lancet (London, England), 1976, Apr-17, Volume: 1, Issue:7964

    Topics: Adolescent; Adult; Agammaglobulinemia; Autoimmune Diseases; Child; Dysgammaglobulinemia; Epilepsy; H

1976
Myelomatosis after phenytoin therapy: a chance association?
    Scandinavian journal of haematology, 1978, Volume: 21, Issue:4

    Topics: Agammaglobulinemia; Bone Neoplasms; Humans; Immunoglobulin G; Immunoglobulin lambda-Chains; Male; Mi

1978
Epilepsy and IgA deficiency--the effect of sodium valproate.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Oct-08, Volume: 52, Issue:16

    Topics: Adult; Agammaglobulinemia; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin A; Male; Phenobar

1977
Diphenylhydantoin-induced hypogammaglobulinemia in a patient infected with human immunodeficiency virus.
    The American journal of medicine, 1991, Volume: 90, Issue:4

    Topics: Adult; Agammaglobulinemia; Hepatitis B; HIV Seropositivity; Homosexuality; Humans; Liver Function Te

1991
Reversible common variable immunodeficiency syndrome induced by phenytoin.
    Archives of internal medicine, 1989, Volume: 149, Issue:6

    Topics: Agammaglobulinemia; Humans; IgG Deficiency; Male; Middle Aged; Phenytoin

1989
Permanent intrinsic B cell immunodeficiency caused by phenytoin hypersensitivity.
    The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:4

    Topics: Adult; Agammaglobulinemia; Antibodies, Monoclonal; B-Lymphocytes; Drug Hypersensitivity; Epilepsy, P

1986
Reversible hypogammaglobulinaemia after diphenylhydantoin and hydroxyzine therapy.
    The Netherlands journal of medicine, 1974, Volume: 17, Issue:6

    Topics: Adult; Agammaglobulinemia; Antibody Formation; gamma-Globulins; Glomerulonephritis; Humans; Hydroxyz

1974
Immunological abnormalities and hydantoins.
    British medical journal, 1972, Jun-03, Volume: 2, Issue:5813

    Topics: Adult; Agammaglobulinemia; Antigens; Epilepsy; Female; Humans; Hydantoins; Immunity, Cellular; Immun

1972