phenytoin has been researched along with Adverse Drug Event in 72 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate topiramate (TPM) and phenytoin (PHT) monotherapy following rapid oral initiation in new-onset epilepsy." | 9.14 | Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: a randomized double-blind clinical trial. ( Faught, E; Hulihan, J; Krumholz, A; Mao, L; Naritoku, D; Privitera, M; Ramsay, E; Schwarzman, L; Wiegand, F, 2010) |
| "To evaluate the efficacy and tolerability of the treatment with valproic acid (VPA) in patients with status epilepticus (SE) or acute repetitive seizures (ARS) comparing it with phenytoin (PHT) treatment." | 9.13 | Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin. ( Dabby, R; Gilad, R; Izkovitz, N; Lampl, Y; Rapoport, A; Sadeh, M; Weller, B, 2008) |
| "Simultaneous administration of phenytoin and isoniazid (INH) in tuberculous meningitis (TBM) or tuberculoma patients with seizures results in higher plasma phenytoin level and thus phenytoin intoxication." | 7.83 | N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study. ( Adole, PS; Kharbanda, PS; Sharma, S, 2016) |
| " This is only the ninth case reported in literature regarding this rare and potentially serious adverse effect of levetiracetam." | 5.51 | Rhabdomyolysis: a rare adverse effect of levetiracetam. ( Ahmed, N; Mirza, MMF; Shaikh, NA; Thomas, L, 2019) |
| "To evaluate topiramate (TPM) and phenytoin (PHT) monotherapy following rapid oral initiation in new-onset epilepsy." | 5.14 | Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: a randomized double-blind clinical trial. ( Faught, E; Hulihan, J; Krumholz, A; Mao, L; Naritoku, D; Privitera, M; Ramsay, E; Schwarzman, L; Wiegand, F, 2010) |
| "To evaluate the efficacy and tolerability of the treatment with valproic acid (VPA) in patients with status epilepticus (SE) or acute repetitive seizures (ARS) comparing it with phenytoin (PHT) treatment." | 5.13 | Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin. ( Dabby, R; Gilad, R; Izkovitz, N; Lampl, Y; Rapoport, A; Sadeh, M; Weller, B, 2008) |
| "Simultaneous administration of phenytoin and isoniazid (INH) in tuberculous meningitis (TBM) or tuberculoma patients with seizures results in higher plasma phenytoin level and thus phenytoin intoxication." | 3.83 | N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study. ( Adole, PS; Kharbanda, PS; Sharma, S, 2016) |
| "Both levetiracetam (LEV) and phenytoin (PHT) were associated with a low risk of early postoperative seizures and a moderate risk of later epilepsy." | 3.74 | Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery. ( Bromfield, EB; Hurwitz, S; Milligan, TA, 2008) |
| "An increased risk for isolated CL/P was found in cases born to mothers treated with amoxicillin, phenytoin, oxprenolol, and thiethylperazine during the second and third month of pregnancy, i." | 3.74 | Drug treatment during pregnancy and isolated orofacial clefts in hungary. ( Czeizel, AE; Métneki, J; Puhó, EH; Szunyogh, M, 2007) |
| "A generalized tonic-clonic seizure (GTCS) is the most severe form of common epileptic seizure and carries the greatest risk of harm." | 2.58 | Antiepileptic drug treatment of generalized tonic-clonic seizures: An evaluation of regulatory data and five criteria for drug selection. ( Bermejo, PE; Gibbs, AA; Huberfeld, G; Kälviäinen, R; Shorvon, SD, 2018) |
| " Recent advancement in bioavailability enhancement of drugs by compounds of herbal origin has produced a revolutionary shift in the way of therapeutics." | 2.48 | A comprehensive review on pharmacotherapeutics of herbal bioenhancers. ( Awale, MM; Chauhan, BN; Dudhatra, GB; Kamani, DR; Kumar, A; Modi, CM; Mody, SK; Patel, HB, 2012) |
| "Moreover, the seizure and the epilepsy type may have been incorrectly diagnosed." | 2.40 | Antiepileptic drug-induced worsening of seizures in children. ( Belmonte, A; Genton, P; Guerrini, R, 1998) |
| "Seizures are commonly encountered in patients who do not have epilepsy." | 2.40 | Medical causes of seizures. ( Delanty, N; French, JA; Vaughan, CJ, 1998) |
| " This is only the ninth case reported in literature regarding this rare and potentially serious adverse effect of levetiracetam." | 1.51 | Rhabdomyolysis: a rare adverse effect of levetiracetam. ( Ahmed, N; Mirza, MMF; Shaikh, NA; Thomas, L, 2019) |
| "Treatment of tacrolimus toxicity includes holding tacrolimus and supportive care." | 1.51 | Treatment of prolonged tacrolimus toxicity using phenytoin in a haemodialysis patient. ( Hamid, M; McGowan, M; Meaney, CJ; O'Connor, M; Su, W, 2019) |
| "Phenytoin (PHT) is an effective and inexpensive antiepileptic drug (AED)." | 1.46 | Risk factors of early adverse drug reactions with phenytoin: A prospective inpatient cohort. ( Ciampi, E; Godoy, J; Mellado, P; Plaza, J; Uribe-San-Martín, R; Uslar, W; Villagra, S, 2017) |
| " We describe a unique adjunct to standard safety assessment wherein the metabolite profile of treated animals is compared with the MetaMap Tox metabolomics database in order to predict the potential for a wide variety of adverse events, including DIKI." | 1.39 | Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling. ( Bush, ED; Fabian, E; Herold, M; Kamp, HG; Krennrich, G; Looser, R; Mattes, WB; Mellert, W; Moeller, N; Nadanaciva, S; Naraoka, H; Omura, K; Piccoli, SP; Prokoudine, A; Ruiz-Noppinger, P; Schuppe-Koistinen, I; Strauss, V; van Ravenzwaay, B; Walk, T, 2013) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects." | 1.32 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004) |
| "Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases." | 1.27 | [Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. ( Wollina, U, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (47.22) | 18.7374 |
| 1990's | 5 (6.94) | 18.2507 |
| 2000's | 12 (16.67) | 29.6817 |
| 2010's | 18 (25.00) | 24.3611 |
| 2020's | 3 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Pedersen, JM | 1 |
| Matsson, P | 1 |
| Bergström, CA | 1 |
| Norinder, U | 1 |
| Hoogstraate, J | 1 |
| Artursson, P | 1 |
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Shervani, S | 1 |
| Madden, W | 1 |
| Gleason, LJ | 1 |
| John, S | 1 |
| Canyuk, B | 1 |
| Anand, TCV | 1 |
| Sukasem, C | 1 |
| Pattharachayakul, S | 1 |
| Alvarado-Alvarado, JA | 3 |
| Salas-Villela, RA | 3 |
| Reyes-Guerrero, JA | 3 |
| Ezquerra-Osorio, A | 3 |
| Thomas, L | 1 |
| Mirza, MMF | 1 |
| Shaikh, NA | 1 |
| Ahmed, N | 1 |
| Uribe-San-Martín, R | 1 |
| Ciampi, E | 1 |
| Uslar, W | 1 |
| Villagra, S | 1 |
| Plaza, J | 1 |
| Godoy, J | 1 |
| Mellado, P | 1 |
| Gillinder, L | 1 |
| Lehn, A | 1 |
| Brown, H | 1 |
| Dionisio, S | 1 |
| Shorvon, SD | 1 |
| Bermejo, PE | 1 |
| Gibbs, AA | 1 |
| Huberfeld, G | 1 |
| Kälviäinen, R | 1 |
| Kwon, SJ | 1 |
| Barletta, JF | 1 |
| Hall, ST | 1 |
| Mangram, AJ | 1 |
| Dzandu, JK | 1 |
| Abdulhamid, M | 1 |
| Zach, V | 1 |
| Meaney, CJ | 1 |
| O'Connor, M | 1 |
| McGowan, M | 1 |
| Hamid, M | 1 |
| Su, W | 1 |
| Mattes, WB | 1 |
| Kamp, HG | 1 |
| Fabian, E | 1 |
| Herold, M | 1 |
| Krennrich, G | 1 |
| Looser, R | 1 |
| Mellert, W | 1 |
| Prokoudine, A | 1 |
| Strauss, V | 1 |
| van Ravenzwaay, B | 1 |
| Walk, T | 1 |
| Naraoka, H | 1 |
| Omura, K | 1 |
| Schuppe-Koistinen, I | 1 |
| Nadanaciva, S | 1 |
| Bush, ED | 1 |
| Moeller, N | 1 |
| Ruiz-Noppinger, P | 1 |
| Piccoli, SP | 1 |
| Polat, I | 1 |
| Karaoglu, P | 1 |
| Ayanoglu, M | 1 |
| Yis, U | 1 |
| Hiz, S | 1 |
| Fuh, L | 1 |
| Hays, H | 1 |
| Brown, N | 1 |
| Shirk, MB | 1 |
| Adole, PS | 1 |
| Kharbanda, PS | 1 |
| Sharma, S | 1 |
| Churchwell, MD | 1 |
| Pasko, DA | 1 |
| Smoyer, WE | 1 |
| Mueller, BA | 1 |
| Milligan, TA | 1 |
| Hurwitz, S | 1 |
| Bromfield, EB | 1 |
| Gilad, R | 1 |
| Izkovitz, N | 1 |
| Dabby, R | 1 |
| Rapoport, A | 1 |
| Sadeh, M | 1 |
| Weller, B | 1 |
| Lampl, Y | 1 |
| Hung, SI | 1 |
| Chung, WH | 1 |
| Liu, ZS | 1 |
| Chen, CH | 1 |
| Hsih, MS | 1 |
| Hui, RC | 1 |
| Chu, CY | 1 |
| Chen, YT | 1 |
| Ramsay, E | 1 |
| Faught, E | 1 |
| Krumholz, A | 1 |
| Naritoku, D | 1 |
| Privitera, M | 1 |
| Schwarzman, L | 1 |
| Mao, L | 1 |
| Wiegand, F | 1 |
| Hulihan, J | 1 |
| Kamiguchi, N | 1 |
| Aoyama, E | 1 |
| Okuda, T | 1 |
| Moriwaki, T | 1 |
| Phillips, EJ | 1 |
| Mallal, SA | 1 |
| Dudhatra, GB | 1 |
| Mody, SK | 1 |
| Awale, MM | 1 |
| Patel, HB | 1 |
| Modi, CM | 1 |
| Kumar, A | 1 |
| Kamani, DR | 1 |
| Chauhan, BN | 1 |
| Winn, LM | 1 |
| Kim, PM | 1 |
| Nickoloff, JA | 1 |
| MOLING, JH | 1 |
| POSCH, JJ | 1 |
| BURNS, JJ | 1 |
| CUCINELL, SA | 1 |
| KOSTER, R | 1 |
| CONNEY, AH | 1 |
| Glick, TH | 1 |
| Workman, TP | 1 |
| Gaufberg, SV | 1 |
| Lin, MS | 1 |
| Dai, YS | 1 |
| Pwu, RF | 1 |
| Chen, YH | 1 |
| Chang, NC | 1 |
| Jose, J | 1 |
| Rao, PG | 1 |
| Puhó, EH | 1 |
| Szunyogh, M | 1 |
| Métneki, J | 1 |
| Czeizel, AE | 1 |
| Jinjuvadia, K | 1 |
| Kwan, W | 1 |
| Fontana, RJ | 1 |
| Leonard, CE | 1 |
| Haynes, K | 1 |
| Localio, AR | 1 |
| Hennessy, S | 1 |
| Tjia, J | 1 |
| Cohen, A | 1 |
| Kimmel, SE | 1 |
| Feldman, HI | 1 |
| Metlay, JP | 1 |
| DeSwarte, RD | 1 |
| D'Arcy, PF | 1 |
| Wollina, U | 1 |
| Roots, I | 1 |
| Knipping, W | 1 |
| Brignola, GP | 1 |
| De Boever, J | 1 |
| Ciancio, SG | 1 |
| Guerrini, R | 1 |
| Belmonte, A | 1 |
| Genton, P | 1 |
| Delanty, N | 1 |
| Vaughan, CJ | 1 |
| French, JA | 1 |
| Fuhs, DW | 1 |
| Wiederholt, JB | 1 |
| Sorkness, CA | 1 |
| Pitterle, ME | 1 |
| Walter, E | 1 |
| Hammond, KB | 1 |
| Windorfer, A | 1 |
| Stünkel, S | 1 |
| Miller, RW | 2 |
| Hashem, N | 1 |
| Shawki, R | 1 |
| Hausmann, K | 2 |
| Skrandies, G | 2 |
| Sachtleben, P | 2 |
| Chabot, F | 1 |
| Aymard, B | 1 |
| Lesur, O | 1 |
| Kheir, A | 1 |
| Moreau, L | 1 |
| Cornette, A | 1 |
| Gerard, H | 1 |
| Delorme, N | 1 |
| Polu, JM | 1 |
| Cramarossa, L | 1 |
| D'Angelo, D | 1 |
| Galassi, A | 1 |
| Puletti, M | 1 |
| Schaefer, O | 1 |
| Stella, VJ | 1 |
| Charman, WN | 1 |
| Naringrekar, VH | 1 |
| Hadnagy, C | 1 |
| Macavei, I | 1 |
| Bornuz, F | 1 |
| Marinca, E | 1 |
| Sass, G | 1 |
| Vesell, ES | 1 |
| Thoenes, W | 1 |
| Thoenes, G | 1 |
| Ansorge, R | 1 |
| Harpey, JP | 1 |
| Parsonage, M | 1 |
| Pochedly, C | 1 |
| Ente, G | 1 |
| Eipe, J | 1 |
| Fraumeni, JF | 1 |
| Cohen, SN | 1 |
| Weber, WW | 1 |
| Fishbein, L | 1 |
| Flamm, WG | 1 |
| Lien, EJ | 1 |
| Gudauskas, GA | 1 |
| Goedde, W | 1 |
| Remmer, H | 1 |
| Kaeser, HE | 1 |
| Brettner, A | 1 |
| Heitzman, ER | 1 |
| Woodin, WG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| A Double-blind Trial Comparing the Efficacy, Tolerability and Safety of Monotherapy Topiramate Versus Phenytoin in Subjects With Seizures Indicative of New Onset Epilepsy[NCT00210782] | Phase 3 | 262 participants (Actual) | Interventional | 2004-06-30 | Completed | ||
| A Retrospective Study to Evaluate Retention Rate of Topiramate With That of Levetiracetam and Oxcarbazepine in a Long-term Epilepsy Treatment[NCT02098941] | 2,500 participants (Anticipated) | Observational | 2014-03-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
17 reviews available for phenytoin and Adverse Drug Event
| Article | Year |
|---|---|
Antiepileptic drug treatment of generalized tonic-clonic seizures: An evaluation of regulatory data and five criteria for drug selection.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug and Narcotic Control; Drug-Related Side Effect | 2018 |
A comprehensive review on pharmacotherapeutics of herbal bioenhancers.
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Benzodioxoles; Biological Availability; Curcu | 2012 |
Vaccine-drug interactions.
Topics: Aminopyrine; BCG Vaccine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans | 1984 |
[Drug-induced gingival proliferation: overview of etiology and treatment].
Topics: Adolescent; Adult; Anticonvulsants; Cyclosporins; Dihydropyridines; Drug-Related Side Effects and Ad | 1995 |
Medications as risk factors for periodontal disease.
Topics: Aging; Alveolar Process; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvuls | 1996 |
Antiepileptic drug-induced worsening of seizures in children.
Topics: Acute Disease; Anticonvulsants; Child; Drug Overdose; Drug-Related Side Effects and Adverse Reaction | 1998 |
Medical causes of seizures.
Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Broncho | 1998 |
Drugs and children: methods for therapeutic monitoring.
Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Ther | 1977 |
[Drugs and the thyroid gland].
Topics: Adrenergic beta-Antagonists; Amiodarone; Carbamazepine; Danazol; Drug-Related Side Effects and Adver | 1987 |
Prodrugs. Do they have advantages in clinical practice?
Topics: Absorption; Adrenal Cortex Hormones; Blood-Brain Barrier; Chloramphenicol; Drug Stability; Drug Ther | 1985 |
Advances in pharmacogenetics.
Topics: Alcohol Oxidoreductases; Catalase; Cholinesterases; Dicumarol; Diseases in Twins; Drug Hypersensitiv | 1973 |
Lupus-like syndromes induced by drugs.
Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stra | 1974 |
Adverse hematologic effects of drugs.
Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents | 1972 |
Drugs affecting therapy with anticoagulants.
Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Intera | 1972 |
Drug-induced cancer.
Topics: Alkylating Agents; Animals; Carcinogens; Diethylstilbestrol; Drug-Related Side Effects and Adverse R | 1972 |
Pharmacogenetics.
Topics: Analgesics; Anemia, Hemolytic; Anesthetics; Apnea; Bone Marrow Diseases; Child; Child, Preschool; Ch | 1972 |
Potential environmental chemical hazards. I. Drugs.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Rela | 1972 |
2 trials available for phenytoin and Adverse Drug Event
| Article | Year |
|---|---|
Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin.
Topics: Acute Disease; Adult; Aged; Anticonvulsants; Brain; Drug-Related Side Effects and Adverse Reactions; | 2008 |
Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: a randomized double-blind clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Child; Dose-Response Relationship, D | 2010 |
Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: a randomized double-blind clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Child; Dose-Response Relationship, D | 2010 |
Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: a randomized double-blind clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Child; Dose-Response Relationship, D | 2010 |
Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: a randomized double-blind clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Child; Dose-Response Relationship, D | 2010 |
53 other studies available for phenytoin and Adverse Drug Event
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Bi | 2008 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
Electronic Health Record Interoperability-Why Electronically Discontinued Medications Are Still Dispensed.
Topics: Accidental Falls; Aged; Anticonvulsants; Clinical Pharmacy Information Systems; Deprescriptions; Dru | 2021 |
Patient, Disease, and Drug-Related Risk Factors Associated with Phenytoin- Induced Cutaneous Adverse Drug Reactions in South Indian Epileptic Patients - A Prospective Case-Control Study.
Topics: Adult; Anticonvulsants; Case-Control Studies; Drug-Related Side Effects and Adverse Reactions; Epile | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Phenytoin as treatment for bidirectional ventricular tachycardia in a patient with anterior myocardial infarction and digoxin toxicity.
Topics: Digoxin; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial In | 2022 |
Rhabdomyolysis: a rare adverse effect of levetiracetam.
Topics: Anticonvulsants; Creatine Kinase; Drug Substitution; Drug-Related Side Effects and Adverse Reactions | 2019 |
Risk factors of early adverse drug reactions with phenytoin: A prospective inpatient cohort.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Drug-Related Side Effects and Adverse Reactions; Fe | 2017 |
Treatment outcomes after the introduction of a new seizure management protocol.
Topics: Adult; Anticonvulsants; Clinical Protocols; Drug-Related Side Effects and Adverse Reactions; Emergen | 2018 |
Lacosamide versus phenytoin for the prevention of early post traumatic seizures.
Topics: Adult; Aged; Anticonvulsants; Brain Injuries, Traumatic; Drug-Related Side Effects and Adverse React | 2019 |
Treatment of prolonged tacrolimus toxicity using phenytoin in a haemodialysis patient.
Topics: Darunavir; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Immunosuppres | 2019 |
Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling.
Topics: Animals; Captopril; Cyclosporine; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Fema | 2013 |
Life-Threatening and Rare Adverse Effects of Phenytoin.
Topics: Anaphylaxis; Anticonvulsants; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions | 2015 |
Characterization of drug overdoses in an Ohio incarcerated population.
Topics: Adult; Aged; Anticonvulsants; Cohort Studies; Critical Care; Drug Overdose; Drug-Related Side Effect | 2016 |
N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.
Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Drug Combinations; Drug-Related Side Effects and | 2016 |
Enhanced clearance of highly protein-bound drugs by albumin-supplemented dialysate during modeled continuous hemodialysis.
Topics: Albumins; Animals; Carbamazepine; Cattle; Drug-Related Side Effects and Adverse Reactions; Hemodialy | 2009 |
Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain; Brain Injuries; Drug Tolerance; Drug-Related | 2008 |
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anticonvulsants; Asian People; Carbamazepine; C | 2010 |
A 96-well plate assay for CYP4503A induction using cryopreserved human hepatocytes.
Topics: Biological Assay; Carbamazepine; Cell Culture Techniques; Cell Membrane; Cells, Cultured; Cryopreser | 2010 |
HLA-B*1502 screening and toxic effects of carbamazepine.
Topics: Anticonvulsants; Asian People; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; HLA-B | 2011 |
Oxidative stress-induced homologous recombination as a novel mechanism for phenytoin-initiated toxicity.
Topics: Animals; CHO Cells; Cricetinae; DNA; DNA Damage; Drug-Related Side Effects and Adverse Reactions; Fe | 2003 |
Acute diphenylhydantoin intoxication: report of two cases.
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Hydantoins; Phenytoin; Psychoses, Substance | 1957 |
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adve | 1965 |
Preventing phenytoin intoxication: safer use of a familiar anticonvulsant.
Topics: Anticonvulsants; Drug-Related Side Effects and Adverse Reactions; Humans; Patient Education as Topic | 2004 |
Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: a case-control study.
Topics: Adult; Allopurinol; Analgesics, Non-Narcotic; Anticonvulsants; Antimetabolites; Carbamazepine; Case- | 2005 |
Pattern of adverse drug reactions notified by spontaneous reporting in an Indian tertiary care teaching hospital.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An | 2006 |
Drug treatment during pregnancy and isolated orofacial clefts in hungary.
Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Amoxicillin; Anti-Bacterial Agents; Antico | 2007 |
Searching for a needle in a haystack: use of ICD-9-CM codes in drug-induced liver injury.
Topics: Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Chemical and Drug Induced Li | 2007 |
Diagnostic E-codes for commonly used, narrow therapeutic index medications poorly predict adverse drug events.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Anti-Arrhythmia Agents; Anticoagulants; Anticonvulsan | 2008 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons | 1984 |
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus | 1984 |
[Genetic causes for the variability of effects and side effects of drugs].
Topics: Debrisoquin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydroxylation; Kinetic | 1982 |
[Problems of evaluating rare adverse drug reactions using as an example agranulocytosis induced by anti-arrhythmia agents].
Topics: Aged; Agranulocytosis; Ajmaline; Anti-Arrhythmia Agents; Drug Therapy, Combination; Drug-Related Sid | 1980 |
The use of serum drug concentrations in a private ambulatory clinic and its affiliated health maintenance organization.
Topics: Adult; Ambulatory Care Facilities; Digoxin; Drug-Related Side Effects and Adverse Reactions; Female; | 1988 |
[Problems and possible errors in monitoring drug side effects at the hospital (author's transl)].
Topics: Adult; Aged; Cholestasis; Diabetes Mellitus; Drug-Related Side Effects and Adverse Reactions; Epilep | 1978 |
[Significance of pharmacogenic liver reactions for metabolism of endogenous and exogenous substances].
Topics: Carbamazepine; Diazepam; Drug-Related Side Effects and Adverse Reactions; Female; Fenoterol; Humans; | 1979 |
Advances in understanding causes of childhood cancer.
Topics: Asbestos; Child; Diethylstilbestrol; Drug-Related Side Effects and Adverse Reactions; Environmental | 1979 |
Cultured peripheral lymphocytes: one biologic indicator of potential drug hazard.
Topics: Adolescent; Antimony; Antimony Potassium Tartrate; Child; Child, Preschool; Chromosomes, Human; Drug | 1976 |
[Current aspects of iatrogenic lesions of the bone marrow].
Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Chloramphenicol; | 1976 |
[Drug-induced pulmonary diseases: diagnostic, therapeutic and prognostic aspects. Apropos of 10 personal case reports].
Topics: Adrenal Cortex Hormones; Adult; Aged; Amiodarone; Ampicillin; Antihypertensive Agents; Benzothiadiaz | 1992 |
Adverse reactions to drugs and metabolic problems perceived in Northern Canadian Indians and Eskimos.
Topics: Adaptation, Biological; Canada; Drug-Related Side Effects and Adverse Reactions; Ethanol; Humans; In | 1986 |
[Bone marrow-damaging effect of various drugs].
Topics: Antitubercular Agents; Bone Marrow; Chloramphenicol; Drug Hypersensitivity; Drug Therapy, Combinatio | 1985 |
Drugs and genes.
Topics: Acetyltransferases; Drug Antagonism; Drug Hypersensitivity; Drug Interactions; Drug-Related Side Eff | 1973 |
[Drug-induced lupus-nephritis light-, electron- and immunfluorescence-microscopic investigations on kidney biopsies (author's transl)].
Topics: Adolescent; Anticonvulsants; Biopsy; Child; Drug-Related Side Effects and Adverse Reactions; Female; | 1972 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec | 1974 |
[Present aspects of bone marrow lesions due to drugs (author's transl)].
Topics: Anemia, Aplastic; Bone Marrow Diseases; Chloramphenicol; Drug-Related Side Effects and Adverse React | 1974 |
Structure side-effect sorting of drugs. I. Extrapyramidal syndrome.
Topics: Anticonvulsants; Basal Ganglia Diseases; Benzamides; Computers; Diazepam; Drug-Related Side Effects | 1973 |
[Pharmacologic basis of metabolic disturbances and drug incompatibilities].
Topics: Cholinesterases; Drug-Related Side Effects and Adverse Reactions; Isoniazid; Pharmacogenetics; Pheny | 1973 |
[The metabolic effect of drugs on their effective strength and duration].
Topics: Animals; Dogs; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Endoplasmic Retic | 1972 |
[Neurotoxicity of drugs].
Topics: Arsenic; Drug-Related Side Effects and Adverse Reactions; Humans; Nervous System Diseases; Nitrofura | 1972 |
Pulmonary complications of drug therapy.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Busulfan; Child; Drug-Related Side Effects and Advers | 1970 |