Compounds > phenytoin
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phenytoin and Adiadochokinesis

phenytoin has been researched along with Adiadochokinesis in 41 studies

Research Excerpts

ExcerptRelevanceReference
"Chronic intoxication of phenytoin (PHT) is a well known cause of cerebellar atrophy or irreversible cerebellar ataxia."8.78[Cerebellar atrophy and persistent cerebellar ataxia after acute intoxication of phenytoin]. ( Ejima, A; Imamura, T; Sahara, M; Saito, H; Tsuburaya, K, 1992)
"A 30-year-old man was given high doses of phenytoin together with 4 antituberculous drugs for a seizure associated with a probable brain tuberculoma."7.70[Residual cerebellar ataxia following acute phenytoin intoxication]. ( al Beladi, K; al Jumah, M; Amene, P; Awada, A, 1999)
"A 42-year-old woman who presented phenytoin intoxication induced by acute hypothyroidism was reported."7.68[A case of phenytoin intoxication induced by hypothyroidism]. ( Fujitake, J; Horii, K; Ishikawa, K; Shimbo, S; Tatsuoka, Y, 1991)
"Reversible chronic cerebellar ataxia followed phenytoin treatment in two epileptic women."7.67Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought. ( Attig, E; Botez, MI; Gravel, J; Vézina, JL, 1985)
"Phenytoin has been considered a possible cause of cerebellar degeneration, especially after clinical intoxication."5.29[Cerebellar atrophy and phenytoin poisoning. An MR study]. ( Aichner, F; Bauer, G; Birbamer, G; Felber, S; Luef, G; Marosi, M, 1993)
"Chronic intoxication of phenytoin (PHT) is a well known cause of cerebellar atrophy or irreversible cerebellar ataxia."4.78[Cerebellar atrophy and persistent cerebellar ataxia after acute intoxication of phenytoin]. ( Ejima, A; Imamura, T; Sahara, M; Saito, H; Tsuburaya, K, 1992)
" Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate."4.77Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985)
"This report presents a 30-year-old man who developed subacute phenytoin-induced cerebellar ataxia and parkinsonism that resolved after discontinuation of the phenytoin treatment."3.73Phenytoin-induced parkinsonism. ( Acar, ZU; Ertan, S; Hanimoglu, H; Kafadar, AM; Kiziltan, G; Tanriverdi, T; Ulu, MO, 2006)
"A 30-year-old man was given high doses of phenytoin together with 4 antituberculous drugs for a seizure associated with a probable brain tuberculoma."3.70[Residual cerebellar ataxia following acute phenytoin intoxication]. ( al Beladi, K; al Jumah, M; Amene, P; Awada, A, 1999)
"A 42-year-old woman who presented phenytoin intoxication induced by acute hypothyroidism was reported."3.68[A case of phenytoin intoxication induced by hypothyroidism]. ( Fujitake, J; Horii, K; Ishikawa, K; Shimbo, S; Tatsuoka, Y, 1991)
"Reversible chronic cerebellar ataxia followed phenytoin treatment in two epileptic women."3.67Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought. ( Attig, E; Botez, MI; Gravel, J; Vézina, JL, 1985)
"Clinical signs of ataxia can persist without radiological evidence of cerebellar atrophy, and cerebellar atrophy is seen without any clinical evidence of cerebellar dysfunction."2.82Phenytoin and damage to the cerebellum - a systematic review of published cases. ( Bradberry, SM; Day, R; Ferner, R, 2022)
" The observed cerebellar ataxia might be due to long-term administration of phenytoin."1.35[Case of juvenile myoclonic epilepsy misdiagnosed as simple partial seizure for more than 60 years]. ( Komori, T; Mizoi, Y; Shimazu, K; Sumita, N; Tamura, N; Yamamoto, T, 2009)
" We consider his cerebellar symptoms and peripheral neuropathy could be attributable to the long-term use of multiple anticonvulsants, i."1.29[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy]. ( Kubota, M; Nagata, J, 1993)
"Phenytoin has been considered a possible cause of cerebellar degeneration, especially after clinical intoxication."1.29[Cerebellar atrophy and phenytoin poisoning. An MR study]. ( Aichner, F; Bauer, G; Birbamer, G; Felber, S; Luef, G; Marosi, M, 1993)
" This would be a manifestation of an independent Phenytoin effect in the high toxic dosage respectively in withdrawal."1.26[EEG in phenytoin intoxication (author's transl)]. ( Mayr, N; Wessely, P, 1981)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199027 (65.85)18.7374
1990's11 (26.83)18.2507
2000's2 (4.88)29.6817
2010's0 (0.00)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Ferner, R1
Day, R1
Bradberry, SM1
Mizoi, Y1
Sumita, N1
Yamamoto, T1
Komori, T1
Tamura, N1
Shimazu, K1
Ertan, S1
Ulu, MO1
Hanimoglu, H1
Tanriverdi, T1
Kafadar, AM1
Acar, ZU1
Kiziltan, G1
Feuerstein, T1
von Reutern, GM1
Cramer, H1
Lindvall, O1
Nilsson, B1
Campbell, WW1
Wessely, P2
Mayr, N2
Binder, H1
Klingler, D1
Rosich Pla, A1
Villa, AM1
Sica, RE1
Ng, WK1
Tan, CT1
Young, GB1
Oppenheimer, SR1
Gordon, BA1
Wells, GA1
Assis, LP1
Kreeft, JH1
Lohuis, NA1
Blume, WT1
Kubota, M1
Nagata, J1
Luef, G1
Marosi, M1
Felber, S1
Birbamer, G1
Aichner, F1
Bauer, G1
Awada, A1
Amene, P1
al Jumah, M1
al Beladi, K1
Pulliainen, V1
Jokelainen, M1
Hedman, C1
Pammo, O1
Ziegler, DK1
Livingston, S1
Pruce, I1
Pauli, LL1
Livingston, HL1
Herberg, KP1
Nagayama, M1
Matsumura, K1
Hokazu, Y1
Maruyama, T1
Omame, M1
Okuda, T1
Imamura, T1
Ejima, A1
Sahara, M1
Saito, H1
Tsuburaya, K1
Horii, K1
Fujitake, J1
Tatsuoka, Y1
Ishikawa, K1
Shimbo, S1
Teta, D1
Uldry, PA1
Regli, F1
Avasthi, R1
Jain, AP1
Reynolds, EH1
Trimble, MR1
Ramsay, RE1
Baier, WK1
Beck, U1
Hirsch, W1
Botez, MI1
Gravel, J1
Attig, E1
Vézina, JL1
Afifi, AK1
Van Allen, MW1
Rawson, MD1
Greenberg, JO1
Selhorst, JB1
Kaufman, B1
Horwitz, SJ1
Igata, A1
Riley, CG1
Gerber, N1
Lynn, R1
Oates, J1
Haring, RD1
Simmons, FB1
Thomas, DJ1
Vallarta, JM1
Bell, DB1
Reichert, A1
Ito, K1
Miyagishi, T1
Takahata, N1
Kruse, R1
La Rosa, JC1
Brown, WV1
Frommer, PL1
Levy, RI1

Reviews

6 reviews available for phenytoin and Adiadochokinesis

ArticleYear
Phenytoin and damage to the cerebellum - a systematic review of published cases.
    Expert opinion on drug safety, 2022, Volume: 21, Issue:7

    Topics: Adult; Ataxia; Atrophy; Cerebellar Ataxia; Cerebellar Diseases; Cerebellum; Humans; Phenytoin

2022
Toxicity to the nervous system of diphenylhydantoin: a review.
    International journal of neurology, 1978, Volume: 11, Issue:4

    Topics: Adrenal Cortex Hormones; Animals; Cardiovascular Diseases; Cerebellar Ataxia; Cerebellar Diseases; C

1978
[Cerebellar atrophy and persistent cerebellar ataxia after acute intoxication of phenytoin].
    No to shinkei = Brain and nerve, 1992, Volume: 44, Issue:2

    Topics: Adult; Atrophy; Cerebellar Ataxia; Cerebellum; Humans; Male; Phenytoin; Tomography, X-Ray Computed

1992
Adverse neuropsychiatric effects of anticonvulsant drugs.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba

1985
Use of phenytoin and carbamazepine in treatment of epilepsy.
    Neurologic clinics, 1986, Volume: 4, Issue:3

    Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognitio

1986
[Ataxia associated with infections and toxicosis].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:8

    Topics: Abdomen; Adult; Animals; Ataxia; Cerebellar Ataxia; Cerebrovascular Disorders; Demyelinating Disease

1971

Other Studies

35 other studies available for phenytoin and Adiadochokinesis

ArticleYear
[Case of juvenile myoclonic epilepsy misdiagnosed as simple partial seizure for more than 60 years].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:1

    Topics: Aged; Cerebellar Ataxia; Diagnostic Errors; Electroencephalography; Electromyography; Epilepsies, Pa

2009
Phenytoin-induced parkinsonism.
    Singapore medical journal, 2006, Volume: 47, Issue:11

    Topics: Adult; Anticonvulsants; Cerebellar Ataxia; Humans; Magnetic Resonance Imaging; Male; Parkinsonian Di

2006
[Phenytoin poisoning in a degradation disorder, report of a case with cerebellar atrophy].
    Der Nervenarzt, 1983, Volume: 54, Issue:2

    Topics: Adult; Atrophy; Cerebellar Ataxia; Cerebellum; Cholestyramine Resin; Electroencephalography; Epileps

1983
Cerebellar atrophy following phenytoin intoxication.
    Annals of neurology, 1984, Volume: 16, Issue:2

    Topics: Adult; Atrophy; Cerebellar Ataxia; Cerebellum; Humans; Male; Phenytoin; Tomography, X-Ray Computed

1984
Periodic alternating nystagmus in phenytoin intoxication.
    Archives of neurology, 1980, Volume: 37, Issue:3

    Topics: Alcoholism; Cerebellar Ataxia; Epilepsy, Post-Traumatic; Humans; Male; Middle Aged; Nystagmus, Patho

1980
[EEG in phenytoin intoxication (author's transl)].
    EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1981, Volume: 12, Issue:3

    Topics: Adult; Central Nervous System Diseases; Cerebellar Ataxia; Dose-Response Relationship, Drug; Electro

1981
[Neurological signs in diphenylhydantoin intoxication (case reports and review) (author's transl)].
    Wiener klinische Wochenschrift, 1981, May-15, Volume: 93, Issue:10

    Topics: Adult; Biopsy; Cerebellar Ataxia; Electroencephalography; Epilepsy; Evoked Potentials; Female; Human

1981
[Permanent cerebellar degeneration secondary to diphenylhydantoin (author's transl)].
    Medicina clinica, 1980, Nov-25, Volume: 75, Issue:9

    Topics: Adult; Alcoholism; Cerebellar Ataxia; Humans; Male; Phenytoin; Seizures

1980
[Persistent cerebellar ataxia after toxic administration of diphenylhydantoin].
    Arquivos de neuro-psiquiatria, 1994, Volume: 52, Issue:4

    Topics: Arachnoid Cysts; Brain Diseases; Cerebellar Ataxia; Epilepsy; Humans; Male; Middle Aged; Phenytoin;

1994
Paroxysmal cerebellar ataxia: use of phenytoin as a provocation test.
    Australian and New Zealand journal of medicine, 1994, Volume: 24, Issue:5

    Topics: Adult; Cerebellar Ataxia; Humans; Male; Phenytoin

1994
Ataxia in institutionalized patients with epilepsy.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1994, Volume: 21, Issue:3

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Anticonvulsants; Ataxia; Cerebellar Ataxia; Epilepsy;

1994
[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy].
    No to shinkei = Brain and nerve, 1993, Volume: 45, Issue:7

    Topics: Adult; Anticonvulsants; Brain; Cerebellar Ataxia; Drug Therapy, Combination; Epilepsy, Generalized;

1993
[Cerebellar atrophy and phenytoin poisoning. An MR study].
    Der Nervenarzt, 1993, Volume: 64, Issue:8

    Topics: Adult; Anticonvulsants; Atrophy; Cerebellar Ataxia; Cerebellum; Dose-Response Relationship, Drug; Dr

1993
[Residual cerebellar ataxia following acute phenytoin intoxication].
    Revue neurologique, 1999, Volume: 155, Issue:4

    Topics: Adult; Anticonvulsants; Atrophy; Brain; Brain Neoplasms; Cerebellar Ataxia; Cerebellum; Epilepsy; Hu

1999
[Cerebellar damage caused by phenytoin intoxication].
    Duodecim; laaketieteellinen aikakauskirja, 1997, Volume: 113, Issue:22

    Topics: Adolescent; Anticonvulsants; Cerebellar Ataxia; Drug Monitoring; Epilepsy; Female; Humans; Phenytoin

1997
The medical treatment of epilepsy: managing side effects of antiepileptic drugs.
    Pediatric annals, 1979, Volume: 8, Issue:4

    Topics: Anticonvulsants; Blood; Cerebellar Ataxia; Child; Child, Preschool; Dextroamphetamine; Drug Eruption

1979
Delayed and insidious onset of diphenylhydantoin toxicity.
    Southern medical journal, 1975, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Animals; Cerebellar Ataxia; Drug Interactions; Electroencephalography; Epilepsy;

1975
[Case of acute encephalopathy due to atropine and phenytoin poisoning diagnosed by urine and blood analysis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Nov-10, Volume: 81, Issue:11

    Topics: Acute Disease; Adult; Atropine; Cerebellar Ataxia; Chromatography, High Pressure Liquid; Consciousne

1992
[A case of phenytoin intoxication induced by hypothyroidism].
    Rinsho shinkeigaku = Clinical neurology, 1991, Volume: 31, Issue:5

    Topics: Acute Disease; Adult; Cerebellar Ataxia; Female; Humans; Hypothyroidism; Phenytoin; Thyroid Gland; T

1991
[Reversible ophthalmoplegia, cerebellar syndrome and vigilance disorders following phenytoin poisoning].
    Schweizerische medizinische Wochenschrift, 1990, Oct-13, Volume: 120, Issue:41

    Topics: Adult; Cerebellar Ataxia; Charcoal; Cognition Disorders; Humans; Male; Ophthalmoplegia; Phenytoin; P

1990
Phenytoin--isoniazid interaction.
    The Journal of the Association of Physicians of India, 1989, Volume: 37, Issue:11

    Topics: Adult; Cerebellar Ataxia; Drug Synergism; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans;

1989
CT findings following diphenylhydantoin intoxication.
    Pediatric radiology, 1985, Volume: 15, Issue:4

    Topics: Adult; Cerebellar Ataxia; Child; Epilepsy; Female; Humans; Phenytoin; Tomography, X-Ray Computed

1985
Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought.
    Neurology, 1985, Volume: 35, Issue:8

    Topics: Adolescent; Cerebellar Ataxia; Cerebellum; Chronic Disease; Cognition; Electroencephalography; Elect

1985
Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.
    Journal of neurology, neurosurgery, and psychiatry, 1968, Volume: 31, Issue:2

    Topics: Adult; Brain; Cerebellar Ataxia; Cerebral Ventriculography; Chlorpromazine; Diplopia; Electroconvuls

1968
Diphenylhydantoin intoxication and cerebrospinal fluid protein.
    Neurology, 1968, Volume: 18, Issue:10

    Topics: Adenosine Triphosphatases; Adult; Cerebellar Ataxia; Cerebrospinal Fluid Proteins; Epilepsy; Female;

1968
The neurological effects of methyl bromide poisoning.
    IMS, Industrial medicine and surgery, 1971, Volume: 40, Issue:4

    Topics: Adult; Amobarbital; Brain Diseases; Bromine; Cerebellar Ataxia; Diazepam; Dimercaprol; Electroenceph

1971
Diphenylhydantoin-induced cerebellar degeneration.
    Archives of neurology, 1972, Volume: 27, Issue:5

    Topics: Adolescent; Cerebellar Ataxia; Cerebellar Diseases; Child; Electroencephalography; Epilepsy; Female;

1972
Chronic hydantoin intoxication: case report.
    The New Zealand medical journal, 1972, Volume: 76, Issue:487

    Topics: Adult; Cerebellar Ataxia; Cognition Disorders; Epilepsy; Female; Humans; Nystagmus, Pathologic; Phen

1972
Acute intoxication with 5,5-diphenylhydantoin (Dilantin) associated with impairment of biotransformation. Plasma levels and urinary metabolites; and studies in healthy volunteers.
    Annals of internal medicine, 1972, Volume: 77, Issue:5

    Topics: Administration, Oral; Adult; Biotransformation; Cerebellar Ataxia; Epilepsy, Tonic-Clonic; Female; H

1972
Cerebellar defects detectable by electronystagmography calibration.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1973, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Astrocytoma; Blindness; Brain Diseases; Cerebellar Ataxia; Cerebellar Disea

1973
Brain damage after lithium and phenytoin.
    British medical journal, 1974, Mar-09, Volume: 1, Issue:5905

    Topics: Brain Diseases; Cerebellar Ataxia; Epilepsy; Female; Humans; Lithium; Phenytoin; Purkinje Cells

1974
Progressive encephalopathy due to chronic hydantoin intoxication.
    American journal of diseases of children (1960), 1974, Volume: 128, Issue:1

    Topics: Adolescent; Brain Diseases; Cerebellar Ataxia; Cerebellum; Child; Electroencephalography; Face; Fema

1974
An electron microscopic study of axonal changes in the cerebellum of diphenyl-hydantoin intoxicated rats. The formation of the so-called "honeycomb structure" in the axoplasm.
    Folia psychiatrica et neurologica japonica, 1970, Volume: 24, Issue:1

    Topics: Animals; Axons; Cerebellar Ataxia; Cerebellum; Cytoplasm; Injections, Intramuscular; Male; Microscop

1970
[Unusual but dangerous hydantoin side effects].
    Monatsschrift fur Kinderheilkunde, 1967, Volume: 115, Issue:4

    Topics: Cerebellar Ataxia; Child; Epilepsy, Temporal Lobe; Humans; Male; Phenytoin

1967
Clofibrate-induced ventricular arrhythmia.
    The American journal of cardiology, 1969, Volume: 23, Issue:2

    Topics: Anticholesteremic Agents; Arrhythmias, Cardiac; Catecholamines; Cerebellar Ataxia; Creatine Kinase;

1969