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phenytoin and Acute Kidney Failure

phenytoin has been researched along with Acute Kidney Failure in 33 studies

Research Excerpts

ExcerptRelevanceReference
"A 38-year old woman receiving phenytoin (diphenylhydantoin) noticed maculopapular erythema as the first manifestation of a syndrome that included acute renal failure and myositis in addition to fever, lymphadenopathy, exfoliative dermatitis, and hepatitis."7.65Reversible renal failure and myositis caused by phenytoin hypersensitivity. ( Michael, JR; Mitch, WE, 1976)
"A 38-year old woman receiving phenytoin (diphenylhydantoin) noticed maculopapular erythema as the first manifestation of a syndrome that included acute renal failure and myositis in addition to fever, lymphadenopathy, exfoliative dermatitis, and hepatitis."3.65Reversible renal failure and myositis caused by phenytoin hypersensitivity. ( Michael, JR; Mitch, WE, 1976)
"The aim of this review was to evaluate current literature for dosing recommendations for the use of antiepileptic medications in patients receiving renal replacement therapy (RRT)."2.53Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. ( Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS, 2016)
"Seizures are commonly encountered in patients who do not have epilepsy."2.40Medical causes of seizures. ( Delanty, N; French, JA; Vaughan, CJ, 1998)
" Although clinicians are aware of the interaction with two widely used antituberculosis agents, rifampin and isoniazid, few reports have described the implications for managing phenytoin dosing in this situation."1.39Phenytoin-rifampin drug interaction in a hypoalbuminemic, renal failure patient: a complex clinical case. ( Hurdle, AC; Twilla, JD; Van Berkel, MA, 2013)
" A loading dose of intravenous phenytoin 2700 mg was administered, followed by maintenance dosing of intravenous phenytoin 150 mg every 8 hours."1.39Phenytoin removal by continuous venovenous hemofiltration. ( Herrmann, DJ; Oltrogge, KM; Peppard, WJ; Regner, KR; Saleh, M, 2013)
"Phenytoin is a commonly used anti-epileptic drug."1.30Early-onset phenytoin toxicity mimicking a renopulmonary syndrome. ( Polman, AJ; Tiebosch, AT; van der Werf, TS; Zijlstra, JG, 1998)
" Serum drug concentration monitoring will be necessary to determine the optimal dosage regimen."1.29Effect of continuous hemofiltration on phenytoin elimination. ( Kronfol, NO; Lau, AH, 1994)
"For phenylbutazone serum binding was decreased in uraemic rabbits, while the binding in homogenates of kidneys and liver was increased."1.26Binding of drugs in serum, blood cells and tissues of rabbits with experimental acute renal failure. ( Belpaire, FM; Bogaert, MG; Van Peer, AP, 1981)
"22 patients with severe preeclampsia-eclampsia were treated in our Intensive Care Unit from 1972 to 1978."1.26[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)]. ( Larsen, R; Radke, J; Turner, E, 1980)
"3 Glycerol-induced acute renal failure produced a significant increase in the unbound fractions of o-methyl red, methyl orange, bromocresol green (BCG), 2-(4'-hydroxybenzeneazo) benzoic acid (HABA), phenytoin and salicylic acid."1.26Decreased binding of drugs and dyes to plasma proteins from rats with acute renal failure: effects of ureter ligation and intramuscular injection of glycerol. ( Bowmer, CJ; Lindup, WE, 1979)
"A case of acute renal failure developing at two separate times after the use of diphenylhydantoin is described."1.26Diphenylhydantoin-induced acute renal failure. ( Agarwal, BN; Cabebe, FG; Hoffman, BI, 1977)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199018 (54.55)18.7374
1990's8 (24.24)18.2507
2000's2 (6.06)29.6817
2010's5 (15.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
von Mässenhausen, A1
Tonnus, W1
Himmerkus, N1
Parmentier, S1
Saleh, D1
Rodriguez, D1
Ousingsawat, J1
Ang, RL1
Weinberg, JM1
Sanz, AB1
Ortiz, A1
Zierleyn, A1
Becker, JU1
Baratte, B1
Desban, N1
Bach, S1
Schiessl, IM1
Nogusa, S1
Balachandran, S1
Anders, HJ1
Ting, AT1
Bleich, M1
Degterev, A1
Kunzelmann, K1
Bornstein, SR1
Green, DR1
Hugo, C1
Linkermann, A1
Van Berkel, MA1
Hurdle, AC1
Twilla, JD1
Velasco, MJ1
McDermott, J1
Oltrogge, KM1
Peppard, WJ1
Saleh, M1
Regner, KR1
Herrmann, DJ1
Smetana, KS1
Cook, AM1
Bastin, ML1
Oyler, DR1
Maslansky, R1
Tutor-Crespo, MJ1
Hermida, J1
Tutor, JC1
Van Peer, AP2
Belpaire, FM2
Rosseel, MT1
Bogaert, MG2
Fichtl, B1
Gerdsmeier, W1
Surman, OS1
Parker, SW1
Larsen, R1
Turner, E1
Radke, J1
Profeta, LM1
Bradbury, K1
Mehl, B1
Lau, AH1
Kronfol, NO1
Polman, AJ1
van der Werf, TS1
Tiebosch, AT1
Zijlstra, JG1
Delanty, N1
Vaughan, CJ1
French, JA1
Roberts, WL1
De, BK1
Coleman, JP1
Annesley, TM1
Gatt, SP1
Trebbin, WM1
Bowmer, CJ2
Lindup, WE3
Ali, M1
Van Peer, A1
Belpaire, F1
Bogaert, M1
Agarwal, BN1
Cabebe, FG1
Hoffman, BI1
Michael, JR1
Mitch, WE1
Maeba, T1
Kondo, S1
Maeda, A1
Ishida, M1
Finan, E1
Trofa, A1
Williams, K1
Itoh, T1
Sawada, Y1
Lin, TH1
Iga, T1
Hanano, M1
Tiula, E1
Haapanen, EJ1
Neuvonen, PJ1
Doherty, JE1
Andreasen, F1
Love, DW1
Salter, FJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Study of Pharmacokinetics of Levetiracetam in Patients Undergoing Intermittent Hemodialysis[NCT04511676]12 participants (Actual)Observational2018-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for phenytoin and Acute Kidney Failure

ArticleYear
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
    Journal of critical care, 2016, Volume: 36

    Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanec

2016
Medical causes of seizures.
    Lancet (London, England), 1998, Aug-01, Volume: 352, Issue:9125

    Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Broncho

1998
Clinical management of established pre-eclampsia and gestational hypertension: an anaesthetist's perspective.
    Bailliere's best practice & research. Clinical obstetrics & gynaecology, 1999, Volume: 13, Issue:1

    Topics: Acute Kidney Injury; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Obstetrical; Anticonvu

1999
Digitalis glycosides. Pharmacokinetics and their clinical implications.
    Annals of internal medicine, 1973, Volume: 79, Issue:2

    Topics: Acute Kidney Injury; Administration, Oral; Arrhythmias, Cardiac; Digitoxin; Digoxin; Drug Interactio

1973

Other Studies

29 other studies available for phenytoin and Acute Kidney Failure

ArticleYear
Phenytoin inhibits necroptosis.
    Cell death & disease, 2018, 03-02, Volume: 9, Issue:3

    Topics: Acute Kidney Injury; Animals; Anticonvulsants; Biopsy; Disease Models, Animal; Gene Knockout Techniq

2018
Phenytoin-rifampin drug interaction in a hypoalbuminemic, renal failure patient: a complex clinical case.
    Pharmacotherapy, 2013, Volume: 33, Issue:6

    Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Dose-Response Relationship, Drug; Drug

2013
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome and hepatitis induced by phenytoin.
    International journal of dermatology, 2014, Volume: 53, Issue:4

    Topics: Acute Kidney Injury; Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Hypersensi

2014
Phenytoin removal by continuous venovenous hemofiltration.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:9

    Topics: Acute Kidney Injury; Anticonvulsants; Critical Illness; Female; Hemofiltration; Humans; Liver Diseas

2013
A prisoner with acute renal failure.
    Lancet (London, England), 2004, May-01, Volume: 363, Issue:9419

    Topics: Acute Kidney Injury; Alcohol Withdrawal Seizures; Anticonvulsants; Humans; Phenytoin

2004
Phenytoin immunoassay measurements in serum samples from patients with renal insufficiency: comparison with high-performance liquid chromatography.
    Journal of clinical laboratory analysis, 2007, Volume: 21, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Female; G

2007
Distribution of antipyrine, phenylbutazone and phenytoin in experimental renal failure.
    Pharmacology, 1981, Volume: 22, Issue:2

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Proteins; Female; Phenylbutazone; Phenytoin; Protein

1981
Binding of drugs in serum, blood cells and tissues of rabbits with experimental acute renal failure.
    Pharmacology, 1981, Volume: 22, Issue:2

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Cells; Blood Proteins; Female; Phenylbutazone; Pheny

1981
Increased plasma protein binding of propranolol in rabbits with acute renal failure.
    Life sciences, 1981, Jan-05, Volume: 28, Issue:1

    Topics: Acute Kidney Injury; Animals; Blood Proteins; Creatinine; Female; Glycerol; Male; Phenytoin; Propran

1981
Complex partial seizures and psychiatric disturbance in end-stage renal disease.
    Psychosomatics, 1981, Volume: 22, Issue:12

    Topics: Acute Kidney Injury; Adult; Anticonvulsants; Electroencephalography; Female; Humans; Methyldopa; Phe

1981
[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)].
    Der Anaesthesist, 1980, Volume: 29, Issue:5

    Topics: Acute Kidney Injury; Adolescent; Adult; Brain Edema; Critical Care; Diazepam; Dihydralazine; Eclamps

1980
Pharmacokinetic considerations in phenytoin pharmacotherapy: preventing overdoses and underdoses.
    The Mount Sinai journal of medicine, New York, 1995, Volume: 62, Issue:4

    Topics: Acute Kidney Injury; Anticonvulsants; Humans; Kidney Failure, Chronic; Monitoring, Physiologic; Phen

1995
Effect of continuous hemofiltration on phenytoin elimination.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Blood Proteins; Hemofiltration; Humans; Male; Phenytoin; Pro

1994
Early-onset phenytoin toxicity mimicking a renopulmonary syndrome.
    The European respiratory journal, 1998, Volume: 11, Issue:2

    Topics: Acute Kidney Injury; Adult; Anticonvulsants; Bronchi; Diagnosis, Differential; Glucocorticoids; Huma

1998
Falsely increased immunoassay measurements of total and unbound phenytoin in critically ill uremic patients receiving fosphenytoin.
    Clinical chemistry, 1999, Volume: 45, Issue:6 Pt 1

    Topics: Acute Kidney Injury; Anticonvulsants; Chromatography, High Pressure Liquid; Critical Illness; Cross

1999
Hemodialysis and pregnancy.
    JAMA, 1979, Apr-27, Volume: 241, Issue:17

    Topics: Acute Kidney Injury; Adolescent; Adult; Chloral Hydrate; Female; Glutethimide; Humans; Infant, Newbo

1979
Decreased binding of drugs and dyes to plasma proteins from rats with acute renal failure: effects of ureter ligation and intramuscular injection of glycerol.
    British journal of pharmacology, 1979, Volume: 66, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Proteins; Coloring Agents; Creatinine; Disease Models, Animal; F

1979
Disposition and pharmacokinetics of phenytoin in rats with acute renal failure [proceedings].
    British journal of pharmacology, 1979, Volume: 66, Issue:3

    Topics: Acute Kidney Injury; Animals; Kinetics; Male; Phenytoin; Rats

1979
Decreased plasma protein binding of o-methyl red, methyl orange and phenytoin (diphenylhydantoin) in rats wtih acute renal failure [proceedings].
    British journal of pharmacology, 1978, Volume: 63, Issue:2

    Topics: Acute Kidney Injury; Animals; Azo Compounds; Blood Proteins; Female; Male; ortho-Aminobenzoates; Phe

1978
Pharmacokinetics of drugs in rabbits with experimental acute renal failure.
    Pharmacology, 1978, Volume: 17, Issue:6

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Proteins; Female; Half-Life; Phenylbutazone; Phenyto

1978
Clinicopathological Conference. Diagnostic difficulties in a case of polypharmacy. Demonstrated at the Royal College of Physicians of London.
    British medical journal, 1977, Jan-22, Volume: 1, Issue:6055

    Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Hepatitis, Vir

1977
Diphenylhydantoin-induced acute renal failure.
    Nephron, 1977, Volume: 18, Issue:4

    Topics: Acute Kidney Injury; Drug Hypersensitivity; Humans; Male; Middle Aged; Phenytoin

1977
Reversible renal failure and myositis caused by phenytoin hypersensitivity.
    JAMA, 1976, Dec-13, Volume: 236, Issue:24

    Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Drug Hypersensitivity; Erythema; Female; Humans

1976
[Acute renal failure associated with miscellaneous drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:6

    Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Cimetidine; Furosemide; Humans; Lithi

1991
Phenytoin hypersensitivity.
    Maryland medical journal (Baltimore, Md. : 1985), 1990, Volume: 39, Issue:6

    Topics: Acute Kidney Injury; Adult; Drug Eruptions; Drug Hypersensitivity; Endocarditis; Humans; Male; Myosi

1990
Kinetic analysis of phenytoin disposition in rats with experimental renal and hepatic diseases.
    Journal of pharmacobio-dynamics, 1988, Volume: 11, Issue:5

    Topics: Acute Kidney Injury; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Male; Models, B

1988
Factors affecting serum protein binding of phenytoin, diazepam and propranolol in acute renal diseases.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:9

    Topics: Acute Kidney Injury; Blood Proteins; Diazepam; Female; Humans; Male; Middle Aged; Phenytoin; Propran

1987
Protein binding of drugs in plasma from patients with acute renal failure.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:6

    Topics: Acute Kidney Injury; Aged; Aspirin; Blood Proteins; Female; Humans; In Vitro Techniques; Male; Middl

1973
Suspected neurotoxicity from intravenous penicillin: a patient case.
    American journal of hospital pharmacy, 1972, Volume: 29, Issue:5

    Topics: Acute Kidney Injury; Ampicillin; Blood Urea Nitrogen; Chronic Disease; Creatine; Diazepam; Gentamici

1972